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Pharmaceutical Injections - 1
Our product range includes a wide range of hydroxocobalamin injection(trineurosol hp injection 1000mcg/ml), 440mg trasturel injection, 440mg trumab trastuzumab injections, propofol injection (troypofol 20ml injection), lox 2% ( lidocaine) injection and insulin glargine injection.
Hydroxocobalamin Injection(Trineurosol HP Injection 1000mcg/Ml)
Product Price: Rs 15 / PieceGet Best Price
Minimum Order Quantity: 10 Piece
Product Brochure
Product Details:
| Composition | Hydroxocobalamin |
| Strength | 1000mcg |
| Pack Size | 2 ml |
| Pack Type | Vial |
| Drug Composition | Methylcobalamin 1000mcg |
| Brand Name | Trineurosol |
| Shelf Life | 36 months |
Hydroxocobalamin Injection (Trineurosol HP Injection 1000 mcg/mL)
Overview: Hydroxocobalamin is a form of vitamin B12 used to treat vitamin B12 deficiency and certain types of cyanide poisoning. It is administered via injection.
Uses:
- Vitamin B12 Deficiency: Treats deficiencies that can lead to anemia and neurological issues.
- Cyanide Poisoning: Acts as an antidote in cases of cyanide exposure.
- Dietary Supplement: Used in individuals with absorption issues or specific dietary needs.
Dosage:
- Typical Dose: Varies based on the condition. For vitamin B12 deficiency, a common regimen may start with 1000 mcg intramuscularly, with adjustments made based on lab results.
- Administration: Administered by a healthcare professional, typically via intramuscular or intravenous injection.
Mechanism of Action:
Hydroxocobalamin works by:
- Replenishing vitamin B12 levels in the body.
- Facilitating the conversion of homocysteine to methionine, which is crucial for DNA synthesis and neurological function.
Side Effects:
- Common: Injection site reactions, headache, dizziness, nausea, and gastrointestinal discomfort.
- Serious: Allergic reactions (rare), which can include difficulty breathing, swelling, or rash. Seek immediate medical attention if these occur.
Precautions:
- Allergies: Inform your healthcare provider of any allergies, especially to cobalt or other vitamin B12 formulations.
- Medical History: Discuss any history of Leber’s disease (a hereditary optic neuropathy) or other health issues with your provider.
Contraindications:
- Known hypersensitivity to hydroxocobalamin or any component of the injection.
Drug Interactions:
- May interact with certain medications, including those that affect absorption (e.g., proton pump inhibitors) or medications that affect blood clotting. Always inform your healthcare provider of all medications you are taking.
Storage:
- Store at room temperature, away from moisture and light. Protect from freezing. Keep out of reach of children.
Patient Counseling:
- Ensure proper injection technique is followed if self-administering.
- Discuss potential side effects and the importance of adhering to the prescribed treatment plan.
- Monitor for signs of deficiency or adverse reactions, and report any concerns to your healthcare provider.
Conclusion:
Hydroxocobalamin Injection (Trineurosol HP) is an effective treatment for vitamin B12 deficiency and a critical intervention for cyanide poisoning. Proper administration, monitoring, and patient education are essential for safe and effective use. Always consult a healthcare professional for personalized medical advice.
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440mg TrastuRel Injection
Product Price: Rs 42,500 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 440 mg |
| Physical Form | Lyophilized Powder |
| Drug Type | Standard Trastuzumab |
| Brand Name | Trastuzumab |
| Manufactured By | Reliance Life Sciences |
| Usage | Hospital |
| Packaging Type | Vial |
Trasturel 440 mg Injection
Overview:
Trasturel (Trastuzumab) is a monoclonal antibody used primarily for the treatment of HER2-positive breast cancer and metastatic gastric cancer. By targeting the HER2 (human epidermal growth factor receptor 2) protein, which is overexpressed in certain types of cancer, Trasturel inhibits the growth of cancer cells. Trasturel is used alone or in combination with other chemotherapy drugs to improve the chances of tumor shrinkage and disease progression.
Indications:
Trasturel 440 mg Injection is indicated for:
- Breast Cancer: HER2-positive breast cancer in early-stage, adjuvant therapy, or metastatic disease.
- Gastric Cancer: HER2-positive metastatic gastric cancer or gastroesophageal junction cancer.
- Other Cancers: May be used in combination with other agents for various cancers expressing HER2.
Mechanism of Action:
Trasturel binds to the HER2 protein, preventing its activation and subsequent signaling that leads to uncontrolled cell growth. This blockage reduces tumor growth and may induce immune-mediated cell death. Trasturel also enhances the effectiveness of chemotherapy by targeting cancer cells for destruction by the immune system.
Dosage and Administration:
- Recommended Dose: For breast cancer, the initial dose is 8 mg/kg as a loading dose, followed by 6 mg/kg every three weeks. For gastric cancer, the typical dose is 8 mg/kg initially, followed by 6 mg/kg every three weeks.
- Administration: Administered by intravenous infusion over 90 minutes initially, followed by 30 minutes for subsequent doses. Healthcare providers should monitor for infusion reactions.
Side Effects:
Common side effects include:
- Fever, chills, and nausea.
- Fatigue and headache.
- Diarrhea and rash. Serious side effects may include:
- Cardiotoxicity: Risk of heart failure, particularly with prolonged use.
- Infusion reactions: Fever, chills, difficulty breathing, and hypotension.
- Pulmonary toxicity: Shortness of breath and cough.
Precautions:
- Cardiac function: Monitor heart function, especially in patients with pre-existing heart conditions.
- Pregnancy: Contraindicated during pregnancy as it can cause fetal harm.
- Infusion Reactions: Monitor patients for signs of infusion-related reactions.
Storage:
Store Trasturel 440 mg Injection in the refrigerator (2°C to 8°C). Do not freeze. Protect from light.
Conclusion:
Trasturel 440 mg Injection is an effective targeted therapy for HER2-positive cancers, particularly breast and gastric cancers. Regular monitoring for heart function and infusion reactions is necessary for patient safety.
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440mg Trumab Trastuzumab Injections
Product Price: Rs 45,000 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 440 mg |
| Physical Form | Lyophilized Powder |
| Drug Type | Standard Trastuzumab |
| Brand | Hermab |
| Treatment | Breast Cancer and Stomach Cancer |
| Composition | Trastuzumab (440mg) |
| Pack Size | 20 ml in 1 vial |
| Manufacturer | RPG Life Sciences Ltd |
Overview: 440mg Trastuzumab Injection contains Trastuzumab, a monoclonal antibody used in the treatment of HER2-positive breast cancer and HER2-positive gastric cancer. Trastuzumab works by targeting and binding to the HER2 receptor on cancer cells, inhibiting tumor growth and promoting the immune system's ability to destroy the cancer cells.
Indications: Trastuzumab 440mg Injection is indicated for:
- HER2-positive Breast Cancer: Treatment of early breast cancer (after surgery) and metastatic breast cancer.
- HER2-positive Gastric Cancer: Treatment of advanced or metastatic gastric cancer with HER2 overexpression.
Mechanism of Action: Trastuzumab binds to the HER2 receptor, which is overexpressed in certain types of cancer cells. By blocking HER2 signaling, Trastuzumab inhibits cell growth and induces antibody-dependent cellular cytotoxicity (ADCC), where immune cells destroy cancer cells. This action slows tumor progression and can shrink existing tumors.
Dosage and Administration:
- Breast Cancer:
- Initial dose: 8mg/kg (loading dose) intravenously, followed by 6mg/kg every 3 weeks.
- Gastric Cancer:
- Initial dose: 8mg/kg intravenously, followed by 6mg/kg every 3 weeks.
The 440mg vial is typically used for patients weighing between 73.3kg to 110kg, but the dose is based on the patient's weight and HER2-positive tumor status.
Side Effects: Common side effects include:
- Fever, nausea, fatigue, and headache.
- Cardiotoxicity: Heart failure, particularly in patients with preexisting heart conditions.
- Infusion-related reactions: Fever, chills, nausea, and fatigue.
- Diarrhea and rash.
Serious side effects may include:
- Severe cardiac events (e.g., heart failure), lung toxicity, and allergic reactions.
Precautions:
- Cardiac function: Monitor heart function, especially in patients with prior heart disease.
- Infusion reactions: Premedication may be needed to prevent reactions.
- Pregnancy: Trastuzumab is contraindicated during pregnancy due to fetal harm.
Storage: Store the vial at 2°C to 8°C. Do not freeze. Keep out of reach of children.
Conclusion: 440mg Trastuzumab Injection is an effective treatment for HER2-positive breast and gastric cancer, blocking tumor growth and enhancing immune response. Careful monitoring for heart function and infusion reactions is necessary.
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Propofol Injection (Troypofol 20ml Injection)
Product Price: Rs 85 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 1% |
| Packaging Size | 20ml |
| Vial Volume | 20 ml |
| Pack Type | Glass Vial |
| Manufacturer | Troikaa |
| Brand | Troypofol |
| Country of Origin | Made in India |
| Usage/Application | General Anaesthesia |
Indications: Propofol is primarily indicated for:
- Induction and maintenance of general anesthesia in adults and pediatric patients.
- Sedation for mechanically ventilated patients in an intensive care setting.
- Procedural sedation (e.g., for diagnostic or therapeutic procedures).
Mechanism of Action: Propofol is a short-acting hypnotic agent. It works by enhancing the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to sedation and anesthesia.
Dosage and Administration:
- Typical Dosage: The dosage depends on the clinical situation, the patient's age, and other factors. For induction of anesthesia in adults, a common dose is 1-2.5 mg/kg administered intravenously. For maintenance, it can be given as a continuous infusion or intermittent boluses.
- Administration: Propofol should be administered by a qualified healthcare professional in a setting equipped for anesthesia.
Side Effects:
- Common: Hypotension, respiratory depression, injection site pain, and dizziness.
- Serious: Anaphylaxis, propofol-related infusion syndrome (PRIS), and severe respiratory depression.
Contraindications:
- Hypersensitivity to propofol or any component of the formulation.
- Caution in patients with a history of egg or soy allergies, as the formulation may contain these ingredients.
Warnings and Precautions:
- Cardiovascular Effects: Monitor blood pressure and heart rate closely, as propofol can cause hypotension.
- Respiratory Depression: Be prepared for airway management and monitoring of respiratory function during and after administration.
- PRIS: This syndrome, characterized by metabolic acidosis, cardiac failure, and rhabdomyolysis, can occur with prolonged infusions of propofol.
Drug Interactions: Propofol may interact with other CNS depressants, leading to enhanced sedation and respiratory depression. Always inform healthcare providers of all medications being taken.
Storage: Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from light. Once opened, the product should be used immediately or stored according to guidelines.
Patient Counseling Information:
- Explain the purpose of the medication and what to expect during the procedure.
- Discuss potential side effects and the need for monitoring during and after administration.
- Advise patients about the importance of reporting any unusual symptoms post-procedure.
Propofol Injection (Troypofol 20 mL) is a widely used anesthetic agent with specific indications for various medical procedures. It should be administered by trained professionals in a controlled environment. Always consult a healthcare professional for personalized medical advice.
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Lox 2% ( Lidocaine) Injection
Product Price: Rs 20 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 2% w/v |
| Packaging Size | 30ml |
| Composition | Lidocaine 2% w/v |
| Brand | Lox |
| Manufacturer | Neon Laboratories Ltd |
| Treatment | Local Anesthesia |
Overview: Lox 2% is a formulation of lidocaine, a local anesthetic commonly used to provide temporary pain relief during various medical procedures. The 2% concentration is effective for a range of applications in both local and regional anesthesia.
Indications for UseLox 2% is indicated for:
- Local Anesthesia: Suitable for minor surgical procedures, dental work, and diagnostic tests.
- Regional Anesthesia: Often used in nerve blocks and epidurals for more extensive pain management.
Lidocaine works by blocking sodium channels in nerve membranes, inhibiting the propagation of nerve impulses. This results in a loss of sensation in the targeted area, providing effective pain relief.
Dosage and Administration- Dosage: The specific dosage depends on the procedure and patient factors. Administered by a healthcare professional, typically through injection.
- Administration Techniques: Can be given locally or in regional blocks, depending on the intended effect.
Common Side Effects:
- Localized swelling or redness at the injection site
- Dizziness or lightheadedness
Serious Side Effects:
- Allergic reactions (rare)
- Systemic toxicity (e.g., seizures, cardiac issues) if absorbed in significant amounts
- Neurological symptoms such as tingling or numbness
- Use with caution in patients with allergies to local anesthetics or those with certain medical conditions (e.g., heart issues, neurological disorders).
- Monitor for signs of toxicity, particularly with higher doses or in sensitive populations.
- Store at room temperature, away from light and moisture.
- Keep out of reach of children.
Patients should be advised to:
- Report any unusual symptoms or side effects to their healthcare provider.
- Understand the procedure and what to expect regarding pain relief and recovery.
Lox 2% (Lidocaine) Injection is an effective local anesthetic for various medical applications. Proper use, monitoring, and patient education are essential to ensure safety and effectiveness. Always consult a healthcare professional for specific advice regarding its administration.
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Insulin Glargine Injection
Product Price: Rs 2,500 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 100 IU/ml |
| Form | Injection |
| Packaging Type | Box |
| Shelf Life | 2 Years |
| Prescription/Non prescription | Prescription |
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Ferric Carboxymaltose Injection (orofer Fcm 500mg / 10ml Injection)
Product Price: Rs 2,260 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 500 mg |
| Brand | Orofer FCM |
| Packaging Type | Single Use Vial |
| Composition | Ferric Carboxymaltose 500mg / 10ml |
| Brand Name | Orofer FCM |
| Manufacturer | Emcure |
| Country of Origin | Made in India |
| Treatment | Lack Of Iron Paleness |
Indications: Ferric carboxymaltose is indicated for:
- Treatment of iron deficiency anemia in adults, particularly in those who have chronic kidney disease (CKD) or are undergoing hemodialysis.
- Management of iron deficiency when oral iron supplementation is inadequate or not tolerated.
Mechanism of Action: Ferric carboxymaltose is an intravenous iron preparation. It provides a source of iron, which is essential for the synthesis of hemoglobin and the formation of red blood cells, thereby improving iron levels and correcting anemia.
Dosage and Administration:
- Typical Dosage: The usual dose for adults is 500 mg (10 mL) administered intravenously. The dosage may vary based on the patient's iron levels and clinical condition.
- Administration: Ferric carboxymaltose can be given as a slow intravenous injection or infusion. The injection should be administered by a healthcare professional.
Side Effects:
- Common: Nausea, vomiting, abdominal pain, and headache.
- Serious: Hypersensitivity reactions (including anaphylaxis), hypotension, and iron overload.
Contraindications:
- Known hypersensitivity to ferric carboxymaltose or any component of the formulation.
- Patients with iron overload syndromes (e.g., hemochromatosis) or non-iron deficiency anemia.
Warnings and Precautions:
- Hypersensitivity: Monitor patients closely for signs of allergic reactions during and after administration.
- Iron Overload: Assess iron status prior to administration and periodically during treatment.
- Injection Site Reactions: Monitor for local reactions at the injection site.
Drug Interactions: Ferric carboxymaltose may interact with other medications, particularly those that affect iron metabolism or may lead to iron overload. Always inform healthcare providers of all medications being taken.
Storage: Store at room temperature (20°C to 25°C / 68°F to 77°F). Protect from light and do not freeze.
Patient Counseling Information:
- Advise patients to report any signs of allergic reactions or severe side effects immediately.
- Discuss the importance of follow-up appointments to monitor iron levels and overall health.
Ferric Carboxymaltose Injection (Orofer FCM 500 mg/10 mL) is an effective treatment for iron deficiency anemia, particularly in specific patient populations. It’s important for patients to be monitored closely during treatment and to communicate any concerns with their healthcare providers. Always consult a healthcare professional for personalized medical advice.
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500mg Maball Rituximab Injection
Product Price: Rs 32,300 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 500 mg |
| Dosage Form | Concentrate |
| Brand | Maball |
| Packaging Size | 50 ml |
| Manufacturer | Hetero |
| Shelf Life | 24 months |
| Packaging Type | Box |
| Composition | Rituximab |
Rituximab 500mg Injection
Overview:
Rituximab is a monoclonal antibody used to treat various cancers and autoimmune diseases, including non-Hodgkin lymphoma (NHL), chronic lymphocytic leukemia (CLL), and rheumatoid arthritis. It targets the CD20 protein on B-cells, leading to B-cell depletion. This helps reduce tumor growth in cancers and modulates immune responses in autoimmune diseases.
Indications:
Rituximab 500mg Injection is indicated for:
- Non-Hodgkin Lymphoma (NHL): Used with chemotherapy for NHL.
- Chronic Lymphocytic Leukemia (CLL): Administered in combination with chemotherapy.
- Rheumatoid Arthritis: For patients who have not responded to other treatments.
- Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA): For induction of remission.
Mechanism of Action:
Rituximab binds to CD20 on B-cells, inducing B-cell depletion. This action inhibits the growth of B-cell malignancies and regulates immune response in diseases like rheumatoid arthritis. Rituximab works by complement-dependent cytotoxicity (CDC), antibody-dependent cellular cytotoxicity (ADCC), and inducing B-cell apoptosis.
Dosage and Administration:
- Recommended Dose: For NHL and CLL, 375 mg/m² is given weekly for several weeks, based on the treatment protocol.
- Administration: Administered intravenously by a healthcare professional. The infusion lasts 4–6 hours.
- Missed Dose: Administer missed doses as soon as possible, unless close to the next dose.
Side Effects:
Common side effects:
- Infusion reactions (fever, chills, rash), fatigue, and nausea.
Serious side effects: - Infections (due to B-cell depletion), tumor lysis syndrome, and cardiovascular issues (arrhythmias).
Precautions:
- Infections: Increased risk of infections; prophylactic measures may be needed.
- Cardiovascular Disease: Caution in patients with heart disease.
- Pregnancy and Breastfeeding: Contraindicated during pregnancy and breastfeeding.
Storage:
Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Keep out of reach of children.
Conclusion:
Rituximab 500mg Injection is effective for treating cancers and autoimmune diseases. Monitoring for side effects is essential.
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Peracetamol + Lignocaine Injection ( Febrinil L Injection )
Product Price: Rs 40 / VialGet Best Price
Minimum Order Quantity: 10 Vial
Product Brochure
Product Details:
| Strength | 2% w/v |
| Pack Size | 20 ml |
| Formulation Type | Injection |
| Packaging Size | 20ml |
| Packaging Type | Ampoule |
| Injection Administeration Type | IM, IV |
| Usage | As local Anesthetic |
| Prescription/Non-Prescription | Prescription |
| Brand Name | Febrinil L |
| Manufacturer By | Svizera |
Overview: Febrinil L Injection is a combination medication that includes paracetamol (acetaminophen) and lignocaine (lidocaine). This dual-action formulation is used for effective pain relief and fever management, making it particularly useful in clinical settings.
Indications for UseFebrinil L Injection is primarily indicated for:
- Pain Management: Effective for treating moderate to severe pain, especially post-operative or procedural pain.
- Fever Reduction: Paracetamol provides antipyretic effects, helping to lower fever and alleviate discomfort.
- Paracetamol: Acts centrally in the brain to inhibit the synthesis of prostaglandins, resulting in analgesic (pain relief) and antipyretic (fever-reducing) effects.
- Lignocaine: Provides local anesthesia by blocking sodium channels in nerve fibers, interrupting the transmission of pain signals.
- Dosage: The specific dosage will depend on the patient's condition, age, and weight. It should be administered by a healthcare professional.
- Administration Route: Typically given via intravenous injection or infusion.
Common Side Effects:
- Nausea or vomiting
- Dizziness
- Local irritation or discomfort at the injection site
Serious Side Effects:
- Allergic reactions (rare)
- Liver damage with high doses of paracetamol
- Neurological symptoms such as seizures or respiratory depression from lignocaine overdose
- Use with caution in patients with liver impairment or allergies to any components.
- Monitor for signs of toxicity, especially in patients with comorbidities or those on other medications.
- Store at room temperature, away from light and moisture.
- Keep out of reach of children.
Patients should be informed to:
- Report any allergies or current medications to their healthcare provider.
- Inform their provider about any unusual symptoms or side effects after administration.
- Understand the importance of follow-up monitoring and care.
Febrinil L Injection effectively combines the analgesic and antipyretic properties of paracetamol with the local anesthetic effects of lignocaine. Proper administration, monitoring, and patient education are essential for achieving the best therapeutic outcomes. Always consult a healthcare professional for specific recommendations regarding its use.
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11.25 Mg Leuprolide Acetate Injection
Product Price: Rs 9,750 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 11.25 mg |
| Formulation Type | Depot |
| Brand | Bdsure |
| Packaging Type | Vial |
| Form | Injection |
| Composition | Leuprolide (11.25mg) |
| Storage | Store in a refrigerator (2 - 8 DegreeC) |
Overview:
11.25mg Leuprolide Acetate Injection contains Leuprolide Acetate, a gonadotropin-releasing hormone (GnRH) agonist used in the treatment of prostate cancer, endometriosis, uterine fibroids, and precocious puberty. Leuprolide works by suppressing the production of sex hormones (testosterone and estrogen) through continuous stimulation of the GnRH receptor, leading to a temporary reduction in hormone levels.
Indications:
11.25mg Leuprolide Acetate Injection is indicated for:
- Prostate Cancer: Treatment of advanced prostate cancer.
- Endometriosis: Management of moderate to severe symptoms of endometriosis.
- Uterine Fibroids: Reduction of symptoms associated with uterine fibroids.
- Precocious Puberty: Treatment of children with early onset of puberty (before age 8 in girls and 9 in boys).
Mechanism of Action:
Leuprolide Acetate, when administered continuously, inhibits the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. This suppression leads to a decrease in testosterone (in men) and estrogen (in women), resulting in the therapeutic effects, such as reducing tumor size, controlling symptoms of endometriosis, or halting premature puberty.
Dosage and Administration:
- Prostate Cancer: 11.25 mg administered as a single intramuscular injection every 3 months.
- Endometriosis: 3.75 mg monthly or 11.25 mg every 3 months.
- Uterine Fibroids: 3.75 mg monthly or 11.25 mg every 3 months.
- Precocious Puberty: Typically 3.75 mg every month, with the 11.25 mg formulation given every 3 months.
Side Effects:
Common side effects include:
- Hot flashes, sweating, and headache.
- Injection site reactions (pain, redness, swelling).
- Mood changes and depression.
Serious side effects may include:
- Cardiovascular issues: Increased risk of cardiovascular events (especially in men with prostate cancer).
- Bone density loss: Long-term use may reduce bone mineral density.
- Ovarian cysts or gastrointestinal discomfort.
Precautions:
- Bone health: Monitor for osteoporosis in patients on long-term therapy.
- Cardiac risk: Monitor for signs of cardiovascular complications, especially in patients with a history of heart disease.
- Pregnancy: Contraindicated during pregnancy due to potential harm to the fetus.
Storage:
Store at room temperature (20°C–25°C). Protect from light and moisture. Do not freeze.
Conclusion:
11.25mg Leuprolide Acetate Injection is a vital treatment for managing hormone-driven conditions such as prostate cancer, endometriosis, and precocious puberty. Close monitoring of bone health and cardiovascular status is recommended during therapy.
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Lignocaine ( Lox Heavy 5% ) Injection
Product Price: Rs 850 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 2% w/v |
| Formulation Type | Injection |
| Packaging Size | 30ml |
| Pack size | 10*5*2 ml |
| Dose/Strength | 5% |
| Composition (Salt) | Lidocaine 5% w/v |
| Brand Name | Lox Heavy |
| Manufacturer By | Neon Laboratories Ltd |
| Treatment | Local anesthesia |
Overview: Lignocaine, also known as lidocaine, is a widely used local anesthetic that provides pain relief for various medical procedures. Lox Heavy 5% refers to a concentrated formulation containing 5% lignocaine, ideal for more extensive anesthetic needs.
Indications for UseLignocaine (Lox Heavy 5%) is primarily indicated for:
- Local Anesthesia: Suitable for minor surgical procedures and dental work.
- Regional Anesthesia: Used in techniques such as epidurals or nerve blocks for surgeries, particularly in the lower body.
Lignocaine works by blocking sodium channels in nerve membranes, inhibiting the propagation of nerve impulses. This action results in localized numbness, effectively reducing pain in the treated area.
Dosage and Administration- Dosage: Administered via injection. The specific dosage will depend on the procedure and the individual patient's needs.
- Administration Techniques: Can be given locally or in regional blocks, depending on the site and extent of anesthesia required.
Common Side Effects:
- Localized swelling or redness at the injection site
- Dizziness or lightheadedness
Serious Side Effects:
- Allergic reactions (rare)
- Systemic toxicity (e.g., seizures, cardiac issues) if absorbed in significant amounts
- Neurological symptoms like tingling or numbness
- Use cautiously in patients with known allergies to local anesthetics or those with specific medical conditions (e.g., heart issues, neurological disorders).
- Monitor patients for signs of toxicity, particularly with higher doses.
- Store at room temperature, away from light.
- Keep out of reach of children.
Patients should be informed to:
- Report any unusual symptoms or side effects to their healthcare provider.
- Understand the procedure and anticipated pain management.
Lignocaine (Lox Heavy 5%) Injection is an effective local anesthetic for various medical applications. Proper use, monitoring, and patient education are essential to maximize safety and effectiveness. Always consult a healthcare professional for specific advice and guidance regarding its administration.
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22.5mg Luprova Leuprolide Acetate Depot Injection
Product Price: Rs 99,900 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 22.5 mg |
| Formulation Type | Depot |
| Packaging Type | Box |
| Brand | Celon Labs |
| Shelf Life | 3 Months |
| Box Contains | Vial And Diluent |
| Form | Injection |
| Usage | Used To Treat Prostate Cancer |
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Streptomycin Injection(Ambistryn-S 0.75gm Injection)
Product Price: Rs 85 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 0.75gm |
| Pack Size | 1 vial |
| Brand | Ambistryn-S |
| Form | Injection |
| Manufacturer | Abbott |
| Packaging Type | Vial |
| Composition | Streptomycin 0.75gm |
| Usage | Tuberculosis (TB) |
Indications: Ambistryn-S (streptomycin) is primarily indicated for:
- Treatment of tuberculosis (TB) as part of a multi-drug regimen.
- Treatment of infections caused by certain susceptible bacteria, including those responsible for plague and tularemia.
- May also be used for other serious infections caused by gram-negative bacteria.
Mechanism of Action: Streptomycin is an aminoglycoside antibiotic that works by inhibiting bacterial protein synthesis. It binds to the 30S ribosomal subunit of bacteria, leading to the misreading of mRNA and ultimately preventing bacterial growth and replication.
Dosage and Administration:
- Typical Dosage: The dosage depends on the type and severity of the infection. For tuberculosis, the usual adult dose is 15 mg/kg (up to 1 gm) intramuscularly once daily.
- Administration: Administered as an intramuscular injection by a healthcare professional. Ensure proper technique to avoid tissue damage.
Side Effects:
- Common: Nausea, vomiting, diarrhea, rash, and dizziness.
- Serious: Nephrotoxicity (kidney damage), ototoxicity (hearing loss), and allergic reactions.
Contraindications:
- Hypersensitivity to streptomycin or any component of the formulation.
- History of significant renal impairment or hearing loss.
Warnings and Precautions:
- Monitoring: Regular monitoring of renal function and hearing is recommended during treatment, especially in patients with pre-existing conditions.
- Pregnancy: Use with caution in pregnant women, as it may cause fetal harm.
Drug Interactions: Streptomycin may interact with other nephrotoxic or ototoxic medications. Inform healthcare providers about all medications being taken, including over-the-counter drugs.
Storage: Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from light. Avoid freezing.
Patient Counseling Information:
- Advise patients on the importance of completing the full course of therapy, even if symptoms improve.
- Discuss potential side effects, especially those related to kidney function and hearing.
- Encourage patients to report any unusual symptoms, particularly changes in hearing or signs of kidney issues.
Ambistryn-S (Streptomycin Injection 0.75 gm) is an effective antibiotic for treating specific bacterial infections, including tuberculosis. Patients should be well-informed about its use, potential side effects, and the importance of adherence to the treatment regimen. Always consult a healthcare provider for personalized medical advice.
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Cetuxa Cetuximab 100 Mg/20 Ml Injection
Product Price: Rs 7,500 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 100 mg |
| Vial Volume | 20 ml |
| Brand | Cetuxa |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging Type | 1 Vial(s) Of 20ml |
| Dose/Strength | 100 mg/20 ml |
| Composition | Cetuximab 100 mg/20 ml |
| Brand Name | Cetuxa |
| Treatment | Cancer |
Overview:
20ml Cetuxa (Cetuximab) Injection contains Cetuximab, a monoclonal antibody used in the treatment of certain head and neck cancers and colorectal cancer. Cetuximab targets the epidermal growth factor receptor (EGFR) on cancer cells, inhibiting the signaling pathways that promote tumor growth. It is typically used in combination with other chemotherapy agents or as a single-agent treatment.
Indications:
20ml Cetuxa (Cetuximab) Injection is indicated for:
- Metastatic Colorectal Cancer (CRC): In combination with chemotherapy for patients whose tumors express EGFR.
- Head and Neck Squamous Cell Carcinoma (HNSCC): For locally advanced or metastatic cases, often in combination with radiation or chemotherapy.
- Non-Small Cell Lung Cancer (NSCLC): In combination with chemotherapy for specific EGFR-expressing tumors.
Mechanism of Action:
Cetuximab binds to the EGFR on cancer cells, blocking the activation of downstream signaling pathways that drive cell division, survival, and tumor progression. By inhibiting EGFR, Cetuximab prevents the growth of tumors and enhances immune system recognition and destruction of cancer cells.
Dosage and Administration:
- Metastatic Colorectal Cancer: Initial dose of 400 mg/m² intravenously, followed by 250 mg/m² weekly.
- Head and Neck Cancer: Initial dose of 400 mg/m² intravenously, followed by 250 mg/m² weekly.
- Non-Small Cell Lung Cancer: Dose varies based on the treatment regimen.
Cetuximab is typically administered intravenously, with infusion rates adjusted based on patient tolerance.
Side Effects:
Common side effects include:
- Infusion reactions (fever, chills, nausea, rash).
- Skin reactions (acneiform rash, dry skin).
- Fatigue, diarrhea, and loss of appetite.
Serious side effects may include:
- Severe allergic reactions (anaphylaxis).
- Lung toxicity, including interstitial lung disease.
- Electrolyte disturbances, such as low magnesium and calcium levels.
Precautions:
- Infusion reactions: Monitor patients during and after infusion, especially during the first dose.
- Cardiopulmonary monitoring: Cetuximab may cause severe reactions, requiring appropriate medical intervention.
- Pregnancy: Cetuximab is contraindicated during pregnancy due to potential harm to the fetus.
Storage:
Store at 2°C to 8°C. Do not freeze. Protect from light.
Conclusion:
20ml Cetuxa (Cetuximab) Injection is a targeted therapy for treating colorectal, head and neck, and certain lung cancers. It works by inhibiting EGFR, blocking tumor growth. Regular monitoring for infusion reactions and skin issues is recommended.
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Thiosol Thiopentone 1mg Injection
Product Price: Rs 35 / VialGet Best Price
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Product Details:
| Strength | 1gm |
| Pack Type | Glass Vial |
| Form | Solution |
| Brand | Thiosol |
| Packaging Size | 1 Injection in 1 Vial |
| Manufacturer | Neon Laboratories Ltd |
| Composition | Thiopentone 1 gm |
| Treatment | Anesthesia |
Overview: Thiosol is an injectable formulation of thiopental sodium, a rapid-acting barbiturate used primarily as an anesthetic. It is known for its sedative and hypnotic properties, making it suitable for various medical procedures.
Indications for UseThiosol Thiopentone Injection is indicated for:
- Induction of Anesthesia: Used for the rapid induction of general anesthesia in surgical procedures.
- Sedation: Provides sedation for patients undergoing procedures that do not require full anesthesia.
- Control of Seizures: May be used in certain cases of status epilepticus to help control seizures.
Thiopental sodium works by enhancing the inhibitory neurotransmitter effects of gamma-aminobutyric acid (GABA) in the central nervous system. This results in sedation and unconsciousness by depressing the activity of the brain.
Dosage and Administration- Dosage: The dosage varies based on the patient's age, weight, and medical condition. Typical induction doses range from 3 to 5 mg/kg intravenously, but the specific amount should be determined by a healthcare professional.
- Administration Route: Given via slow intravenous injection.
Common Side Effects:
- Drowsiness or dizziness
- Hypotension (low blood pressure)
- Respiratory depression
Serious Side Effects:
- Allergic reactions (rare)
- Cardiovascular instability, especially in high-risk patients
- Use with caution in patients with a history of respiratory issues, cardiovascular problems, or hypersensitivity to barbiturates.
- Monitor vital signs closely during administration and recovery.
- Ensure appropriate resuscitation equipment is available, as thiopental can cause respiratory depression.
- Store at room temperature, protected from light.
- Keep out of reach of children.
Patients should be advised to:
- Inform healthcare providers about any allergies or medical conditions prior to the procedure.
- Discuss any medications they are taking to avoid potential interactions.
- Be aware of post-anesthesia recovery instructions and the need for someone to assist them after the procedure.
Thiosol Thiopentone 1 mg Injection is a vital medication for inducing anesthesia and providing sedation. Proper administration and monitoring are crucial to ensure patient safety and effectiveness during medical procedures. Always consult a healthcare professional for specific guidance regarding its use.
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Pemetrexed 100 Mg Injection (Pemetero 100 Mg Injection)
Product Price: Rs 1,200 / VialGet Best Price
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Product Details:
| Strength | 100 mg |
| Pack Type | Vial |
| Brand Name | Pemetero |
| Manufacturer | Hetero Drugs Ltd |
| Packaging Size | 1 Injection in 1 Vial |
Pemetrexed Injection (Pemetero 100 mg)
Indications:
Pemetrexed is indicated for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) and malignant pleural mesothelioma. It is often used in combination with other chemotherapy agents.
Mechanism of Action:
Pemetrexed is an antifolate that inhibits multiple enzymes involved in purine and pyrimidine synthesis, including thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase. This inhibition disrupts DNA and RNA synthesis, leading to cancer cell death.
Dosage and Administration:
- Dosage: The typical recommended dose of pemetrexed for NSCLC is 100 mg/m² administered intravenously. Dosing may vary based on the specific treatment regimen and patient tolerance.
- Administration: Administer via intravenous infusion over 10 minutes. Proper hydration is recommended prior to administration, and premedication with folic acid and vitamin B12 may be used to reduce toxicity.
Contraindications:
- Hypersensitivity to pemetrexed or any component of the formulation.
- History of severe hypersensitivity reactions to other antifolate agents.
Warnings and Precautions:
- Bone Marrow Suppression: Monitor blood counts regularly, as pemetrexed can cause leukopenia, thrombocytopenia, and anemia.
- Renal Impairment: Use with caution in patients with renal dysfunction; dosage adjustments may be necessary based on creatinine clearance.
- Gastrointestinal Toxicity: Be vigilant for signs of gastrointestinal toxicity, such as diarrhea or mucositis.
Side Effects:
Common side effects may include:
- Nausea
- Vomiting
- Fatigue
- Rash
- Anorexia
Serious side effects can include:
- Severe allergic reactions
- Bone marrow suppression
- Renal impairment
Drug Interactions:
Pemetrexed may interact with other medications that affect renal function or hematologic parameters. Patients should inform their healthcare provider about all medications they are taking.
Storage:
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Do not freeze.
Patient Counseling Information:
- Advise patients to report any signs of infection, unusual bruising or bleeding, or gastrointestinal symptoms.
- Emphasize the importance of adhering to the treatment schedule and attending regular follow-up appointments for blood count monitoring.
- Encourage patients to maintain adequate hydration and a balanced diet during treatment.
Conclusion:
Pemetrexed is a valuable treatment option for non-small cell lung cancer and malignant pleural mesothelioma. Ongoing communication with healthcare providers is crucial for managing potential side effects and optimizing treatment outcomes. Always consult with a healthcare professional for personalized medical advice.
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2mg Bortezomib Injection
Product Price: Rs 1,250 / VialGet Best Price
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Product Details:
| Dose/Strength | 2 mg |
| Brand | Bortenat |
| Storage Condition | Store below 25 DegreeC |
| Manufactured By | Natco Pharma Ltd |
| Treatment | Multiple Myeloma |
Bortezomib 2 mg Injection (Bortenat 2 mg Injection)
Indications:
Bortezomib is indicated for the treatment of multiple myeloma and certain types of lymphoma, specifically in patients who have received at least one prior therapy.
Mechanism of Action:
Bortezomib is a proteasome inhibitor that disrupts the proteasome's function, leading to the accumulation of regulatory proteins that promote apoptosis (programmed cell death) in cancer cells. This mechanism helps to inhibit tumor growth and induce cell death.
Dosage and Administration:
- Dosage: The recommended dose of Bortezomib is typically 1.3 mg/m² administered intravenously or subcutaneously on days 1, 4, 8, and 11 of a 21-day treatment cycle. Dosage may vary based on the specific condition and patient response.
- Administration: Administer via intravenous infusion or subcutaneous injection. Rotate injection sites to minimize discomfort.
Contraindications:
- Hypersensitivity to bortezomib or any component of the formulation.
- Caution is advised in patients with a history of neuropathy.
Warnings and Precautions:
- Neuropathy: Monitor for symptoms of peripheral neuropathy and adjust dosing as necessary.
- Infections: Increased risk of infections; monitor patients closely for signs of infection.
- Blood Disorders: Regularly assess blood counts, as bortezomib can cause thrombocytopenia and neutropenia.
Side Effects:
Common side effects may include:
- Nausea
- Fatigue
- Diarrhea
- Peripheral neuropathy
- Thrombocytopenia
Serious side effects can include:
- Severe allergic reactions
- Cardiac issues, including congestive heart failure
- Infections
Drug Interactions:
Bortezomib may interact with other medications, particularly those that affect blood clotting or immune function. Patients should inform their healthcare provider of all medications they are taking.
Storage:
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to report any signs of infection, unusual bruising or bleeding, or symptoms of neuropathy.
- Discuss the importance of adhering to the treatment schedule and regular follow-up appointments.
- Encourage patients to maintain a healthy lifestyle, including proper nutrition and hydration, to support overall health during treatment.
Conclusion:
Bortezomib is an effective treatment option for multiple myeloma and certain lymphomas, helping to improve patient outcomes through its targeted mechanism of action. Ongoing communication with healthcare providers is essential for managing side effects and optimizing therapy. Always consult with a healthcare professional for personalized medical advice.
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Lidocaine (2%) + Adrenaline (0.005MG) Lox 2% Adrenaline Injection
Product Price: Rs 20 / VialGet Best Price
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Product Details:
| Packaging Size | 30ml |
| Dose/Strength | Lidocaine 2%, Adrenaline 0.005mg |
| Pack Size | 30 ml Injection in 1 Vial |
| Composition (salt) | Lidocaine (2%) + Adrenaline (0.005mg) |
| Brand Name | Lox |
| Manufacturer By | Neon Laboratories Ltd |
| Treatment | Local anesthesia (Numb tissues in a specific area) |
Overview: Lox 2% Adrenaline Injection is a combination of lidocaine, a local anesthetic, and adrenaline (epinephrine), a vasoconstrictor. This formulation is used to provide effective pain relief while minimizing bleeding during surgical procedures.
Indications for UseLox 2% Adrenaline Injection is primarily indicated for:
- Local Anesthesia: Provides anesthesia for minor surgical procedures, dental work, and diagnostic tests.
- Hemostasis: The addition of adrenaline helps reduce bleeding in the surgical area by constricting blood vessels.
- Lidocaine (2%): Blocks sodium channels in nerve membranes, inhibiting nerve impulse transmission, which results in localized numbness.
- Adrenaline (0.005 mg): Causes vasoconstriction, reducing blood flow to the area, which prolongs the anesthetic effect and minimizes bleeding during procedures.
- Dosage: The specific dosage depends on the procedure and patient factors. Typical administration involves injecting a small volume into the affected area.
- Administration Route: Usually given via local injection; the total volume and concentration may vary based on the clinical situation.
Common Side Effects:
- Localized swelling or redness at the injection site
- Nausea or dizziness
Serious Side Effects:
- Allergic reactions (rare)
- Systemic toxicity from lidocaine (e.g., seizures, cardiovascular issues) if absorbed in significant amounts.
- Increased heart rate or blood pressure from adrenaline, especially in sensitive patients.
- Use with caution in patients with known allergies to local anesthetics or adrenaline.
- Monitor patients for signs of toxicity, particularly with higher doses or sensitive populations.
- Avoid use in areas with compromised blood flow.
- Store at room temperature, away from light and moisture.
- Keep out of reach of children.
Patients should be advised to:
- Inform healthcare providers about any known allergies or medications they are taking.
- Report any unusual symptoms or side effects, particularly signs of systemic reactions like increased heart rate or allergic responses.
- Understand the importance of follow-up care and monitoring after the procedure.
Lidocaine (2%) + Adrenaline (0.005 mg) (Lox 2% Adrenaline Injection) is an effective local anesthetic for various medical applications, particularly when hemostasis is needed. Proper administration, monitoring, and patient education are crucial for maximizing therapeutic benefits while minimizing risks. Always consult a healthcare professional for specific guidance regarding its use.
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Etomidate Injection (Hypnodate 2mg/ml Injection)
Product Price: Rs 225 / VialGet Best Price
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Product Details:
| Strength | 20 mg/ 10 ml |
| Dose/Strength | 2 mg/ml |
| Pack Size | 10 ml |
| Composition | Etomidate 2 mg/ml |
| Brand Name | Hypnodate |
| Manufacturer By | Neon Laboratories Ltd |
| Usage/Application | General Anesthesia |
Overview: Etomidate is an injectable anesthetic agent known for its rapid onset and short duration of action. It is primarily used for the induction of general anesthesia and sedation in various medical procedures.
Indications for UseHypnodate 2 mg/mL Injection is indicated for:
- Induction of Anesthesia: Used for rapid induction of general anesthesia, especially in patients with cardiovascular instability.
- Procedural Sedation: Provides sedation for short procedures or for patients requiring sedation in critical care settings.
Etomidate works by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor. This results in CNS depression, leading to sedation and loss of consciousness.
Dosage and Administration- Dosage: Typical adult induction doses range from 0.1 to 0.3 mg/kg, administered intravenously. The specific dose should be determined by the healthcare provider based on the patient’s condition and response.
- Administration Route: Given via slow intravenous injection.
Common Side Effects:
- Pain or discomfort at the injection site
- Dizziness or sedation
- Nausea
Serious Side Effects:
- Adrenal suppression: Prolonged use may inhibit adrenal gland function, leading to decreased cortisol production.
- Allergic reactions (rare)
- Use with caution in patients with known adrenal insufficiency or those at risk for adrenal suppression.
- Continuous monitoring of vital signs is essential during and after administration.
- Ensure resuscitation equipment is available, as etomidate can cause respiratory depression in sensitive individuals.
- Store at room temperature, away from light and moisture.
- Keep out of reach of children.
Patients should be advised to:
- Inform healthcare providers about any allergies, especially to medications.
- Discuss any medical conditions, particularly adrenal issues, before administration.
- Understand that sedation may affect their ability to perform tasks afterward and that assistance may be needed.
Etomidate Injection (Hypnodate 2 mg/mL) is a valuable agent for the induction of anesthesia and procedural sedation. Proper administration, monitoring, and patient education are crucial for ensuring safety and effectiveness during medical procedures. Always consult a healthcare professional for personalized guidance regarding its use.
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Zoledronic Acid 4 mg Injection (Zolasta3 4mg Injection)
Product Price: Rs 1,550 / VialGet Best Price
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Product Details:
| Dose/Strength | 4 mg |
| Packaging Size | 1 Injection in 1 vial |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Brand Name | Zolasta |
| Uses | Osteoporosis |
Zoledronic Acid Injection (Zolasta 4 mg)
Indications:
Zoledronic acid is indicated for the treatment and prevention of osteoporosis in postmenopausal women and men, for the treatment of glucocorticoid-induced osteoporosis, for Paget's disease of bone, and to prevent skeletal-related events in patients with bone metastases from solid tumors and in multiple myeloma.
Mechanism of Action:
Zoledronic acid is a bisphosphonate that inhibits osteoclast-mediated bone resorption. By decreasing bone turnover, it helps increase bone mineral density and reduces the risk of fractures and skeletal-related events.
Dosage and Administration:
Dosage: The recommended dose is typically 4 mg administered as an intravenous infusion once a year for osteoporosis, or as specified for other indications.
Administration: Administer via intravenous infusion over at least 15 minutes. Ensure proper hydration before administration.
Contraindications:
Hypersensitivity to zoledronic acid or any component of the formulation.
Severe renal impairment (creatinine clearance <30 mL/min).
Warnings and Precautions:
Renal Function: Monitor renal function before each dose and periodically during treatment. Dose adjustments may be necessary for patients with renal impairment.
Hypocalcemia: Correct hypocalcemia prior to treatment, as zoledronic acid can exacerbate this condition.
Osteonecrosis of the Jaw: Patients should be assessed for dental issues and receive appropriate dental care before initiating treatment.
Side Effects:
Common side effects may include:
Fatigue
Nausea
Fever
Bone pain
Headache
Serious side effects can include:
Renal impairment
Osteonecrosis of the jaw
Severe allergic reactions
Drug Interactions:
Zoledronic acid may interact with other medications affecting renal function or electrolytes. Patients should inform their healthcare provider of all medications they are taking.
Storage:
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Do not freeze.
Patient Counseling Information:
Advise patients to report any signs of jaw pain, swelling, or dental problems, which may indicate osteonecrosis of the jaw.
Discuss the importance of adhering to the treatment schedule and attending regular follow-up appointments for monitoring renal function and bone health.
Encourage patients to maintain adequate hydration and a balanced diet rich in calcium and vitamin D.
Conclusion:
Zoledronic acid is an effective treatment for osteoporosis and related conditions, improving bone health and reducing fracture risk. Continuous communication with healthcare providers is essential for managing potential side effects and ensuring optimal treatment outcomes. Always consult with a healthcare professional for personalized medical advice.
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400mg Bevacizumab Injection
Product Price: Rs 7,250 / VialGet Best Price
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Product Details:
| Strength | 400 mg/16 ml |
| Brand | Bevacirel |
| Manufacturer | Reliance Life Sciences |
| Form | Injection |
| Treatment | Kidney Cancer |
| Composition | Bevacizumab 400mg |
| Storage Condition | 2 DegreeC to 8 DegreeC (36 DegreeF to 46 DegreeF) |
Bavacizumab 400 mg/16 ml Injection (Bevacirel 400 mg/16 ml Injection)
Indications:
Bavacizumab is indicated for the treatment of various cancers, including metastatic colorectal cancer, non-small cell lung cancer, glioblastoma, renal cell carcinoma, and cervical cancer. It is typically used in combination with other chemotherapy agents.
Mechanism of Action:
Bavacizumab is a monoclonal antibody that inhibits vascular endothelial growth factor (VEGF). By binding to VEGF, it prevents the activation of its receptors, thereby inhibiting angiogenesis (the formation of new blood vessels). This action helps to starve tumors of the necessary blood supply for growth and metastasis.
Dosage and Administration:
- Dosage: The recommended dose of Bavacizumab is typically 5 mg/kg or 10 mg/kg administered via intravenous infusion, depending on the specific cancer type and treatment regimen.
- Administration: Administer as an intravenous infusion over 30 to 90 minutes. Initial doses may be given over a longer period to monitor for infusion reactions.
Contraindications:
- Hypersensitivity to bavacizumab or any component of the formulation.
- Recent surgery or active bleeding disorders.
Warnings and Precautions:
- Monitor for signs of gastrointestinal perforation, hemorrhage, and wound healing complications.
- Use caution in patients with a history of cardiovascular disease.
- Regularly assess blood pressure, as hypertension can occur with treatment.
Side Effects:
Common side effects may include:
- Hypertension
- Fatigue
- Headache
- Nausea
- Diarrhea
- Abdominal pain
Serious side effects can include:
- Gastrointestinal perforations
- Arterial thromboembolic events
- Hemorrhage
- Impaired wound healing
Drug Interactions:
Bavacizumab may interact with other medications that affect blood pressure, anticoagulants, and other anti-cancer therapies. Inform your healthcare provider about all medications you are taking.
Storage:
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Patient Counseling Information:
- Advise patients to report any unusual symptoms, such as severe headaches, visual disturbances, or signs of bleeding.
- Discuss the importance of regular monitoring for blood pressure and other potential side effects.
Conclusion:
Bavacizumab is a targeted therapy that can significantly impact cancer treatment through its mechanism of inhibiting angiogenesis. Ongoing communication with healthcare providers is essential for managing side effects and ensuring the best therapeutic outcomes. Always consult with a healthcare professional for personalized medical advice.
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100IU Xeomin Botulinum Neurotoxin Injection
Product Price: Rs 11,650 / PieceGet Best Price
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Product Details:
| Strength | 100 Units |
| Composition | Botulinum Neurotoxin |
| Injectable Form | Lyophilized Powder |
| Packaging Size | Vial |
| Shelf Life | 24 Months |
| Brand Name | Xeomin |
Description:
Botulinum neurotoxin, specifically Xeomin, is a purified protein used for various medical conditions. It works by blocking nerve signals to the muscles, resulting in temporary muscle paralysis. This can help treat specific muscle disorders and reduce symptoms associated with certain neurological conditions.
Indications:
Xeomin is indicated for:
- Chronic Migraines: Reducing the frequency and severity of migraine headaches.
- Cervical Dystonia: Treating severe neck spasms.
- Blepharospasm: Managing involuntary blinking.
- Spasticity: Reducing muscle stiffness in the upper limbs.
Dosage and Administration:
- Dosage: The specific dosage varies based on the condition being treated. For chronic migraines, doses typically range from 155 to 195 units, while cervical dystonia may require doses of 120 units or more, depending on individual response.
- Administration: Administered via intramuscular injection by a qualified healthcare provider. Effects usually take a few days to manifest and can last for several months.
Common Side Effects:
- Pain at the injection site
- Headache
- Muscle weakness
- Dry mouth
- Flu-like symptoms
Precautions:
- Medical History: Inform the healthcare provider of any medical conditions, especially neuromuscular disorders or allergies.
- Pregnancy and Breastfeeding: Consult a healthcare provider before use, as safety during pregnancy and breastfeeding has not been established.
- Avoiding Blood Thinners: Inform the provider about any anticoagulant medications, as these may increase the risk of bruising.
Conclusion:
Botulinum neurotoxin (Xeomin 100 IU) is an effective treatment for various medical conditions, including chronic migraines, cervical dystonia, and spasticity. Administration should be performed by a qualified healthcare professional, with careful monitoring for side effects and individual response to treatment.
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40mg Irinotecan Injection
Product Price: Rs 1,300 / VialGet Best Price
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Product Details:
| Strength | 40 mg/ 2 ml |
| Packaging Type | Vial |
| Brand | Torsirin |
| Storage Condition | Store below 30 DegreeC |
| Manufacturer | Miracalus Pharma Pvt Ltd |
| Treatment | Cancer of Colon and Rectum |
Irinotecan 40 mg/2 ml Injection (Torsirin 40 mg/2 ml Injection)
Indications:
Irinotecan is indicated for the treatment of metastatic colorectal cancer, either as a single agent or in combination with other chemotherapeutic agents. It is particularly effective in patients who have failed prior therapies.
Mechanism of Action:
Irinotecan is a topoisomerase I inhibitor that interferes with DNA replication. It is converted to its active form, SN-38, which binds to and inhibits topoisomerase I, causing DNA damage and apoptosis in cancer cells.
Dosage and Administration:
- Dosage: The recommended dose of Irinotecan is typically 180 mg/m² administered intravenously every two weeks. Dosage may vary based on the specific treatment regimen and patient tolerance.
- Administration: Administer as an intravenous infusion over 30 to 90 minutes. Ensure proper hydration and premedication as necessary.
Contraindications:
- Hypersensitivity to irinotecan or any component of the formulation.
- Diarrhea or bowel obstruction in patients with a history of significant gastrointestinal conditions.
Warnings and Precautions:
- Diarrhea: Monitor closely for severe diarrhea, which can be life-threatening. Administer antidiarrheal agents as needed.
- Bone Marrow Suppression: Regularly assess blood counts, as irinotecan can cause leukopenia, neutropenia, and thrombocytopenia.
- Hepatic Impairment: Dose adjustments may be necessary in patients with liver dysfunction.
Side Effects:
Common side effects may include:
- Diarrhea
- Nausea
- Vomiting
- Fatigue
- Abdominal pain
Serious side effects can include:
- Severe diarrhea
- Neutropenic fever
- Dehydration
Drug Interactions:
Irinotecan may interact with other medications, particularly those affecting liver enzymes and drugs that may exacerbate diarrhea. Patients should inform their healthcare provider of all medications they are taking.
Storage:
Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Protect from light and moisture. Do not freeze.
Patient Counseling Information:
- Advise patients to report any signs of severe diarrhea, nausea, or unusual bleeding.
- Discuss the importance of adhering to the treatment schedule and attending regular follow-up appointments for blood count monitoring.
- Encourage patients to stay well-hydrated and to maintain a balanced diet during treatment.
Conclusion:
Irinotecan is an effective chemotherapy agent for metastatic colorectal cancer, offering patients a treatment option with a targeted mechanism of action. Continuous communication with healthcare providers is essential for managing side effects and ensuring optimal treatment outcomes. Always consult with a healthcare professional for personalized medical advice.
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Phenylephrine Hydrochloride (Phenpres 10mg Injection)
Product Price: Rs 198 / BoxGet Best Price
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Product Details:
| Packaging Size | 1 Ampule of 10ml |
| Strength | 10mg |
| Brand | Phenpres |
| Manufacturer | Neon |
| Composition | Phenylephrine Hcl |
| Form | injection |
| Usage/Application | Hospital |
| Generic Name | Phenylephrine |
Overview: Phenylephrine is a selective alpha-1 adrenergic agonist used primarily as a vasopressor to increase blood pressure and as a decongestant. It is often administered intravenously in clinical settings.
Indications:
- Hypotension: Used to treat acute hypotension, particularly in surgical settings or during anesthesia.
- Nasal Congestion: Sometimes used as a nasal decongestant (though this is more common in oral formulations).
Mechanism of Action: Phenylephrine works by stimulating alpha-1 adrenergic receptors, leading to vasoconstriction (narrowing of blood vessels). This increases systemic vascular resistance and, consequently, blood pressure.
Dosage and Administration:
- Dosage: The usual initial intravenous dose for hypotension is 0.5 to 1 mg, which may be repeated as necessary. Dosage adjustments should be based on the patient’s response.
- Administration: Administered intravenously, typically as a slow injection or continuous infusion. Blood pressure should be monitored closely during administration.
Contraindications:
- Severe hypertension or tachycardia.
- Hypersensitivity to phenylephrine or any component of the formulation.
- Patients taking monoamine oxidase inhibitors (MAOIs).
Warnings and Precautions:
- Use with caution in patients with cardiovascular disease, as it can cause increased blood pressure.
- Monitor for signs of extravasation, which can cause tissue necrosis.
Side Effects:
- Common: Headache, dizziness, anxiety, and palpitations.
- Serious: Hypertension, bradycardia, and potential for reflex bradycardia due to increased blood pressure.
Drug Interactions:
- May interact with other medications affecting blood pressure or those that are MAOIs. Always inform healthcare providers of all medications being taken.
Storage:
- Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from light. Keep out of reach of children.
Patient Counseling:
- Inform patients about the purpose of the injection and potential side effects.
- Advise them to report any unusual symptoms, especially those related to heart function or blood pressure changes.
Conclusion: Phenylephrine Hydrochloride (Phenpres 10 mg Injection) is an effective agent for managing hypotension and is used in various clinical settings. Proper administration and monitoring are essential for safety and effectiveness. Always consult a healthcare professional for personalized medical advice.
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Esentra Denosumab 120mg Injection
Product Price: Rs 18,500 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 120 mg |
| Dose/Strength | 120 mg |
| Packaging Type | Single-dose Vial |
| Brand | Esentra |
| Packaging Size | 1.7 ml |
| Composition | Denosumab 120mg/1.7ml |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Brand Name | Esentra |
| Treatment | Osteoporosis,bone loss,giant cell tumour of the bone,high calcium levels. |
Overview: Esentra is a medication containing denosumab, a monoclonal antibody used primarily to treat bone-related conditions. It works by inhibiting RANKL (Receptor Activator of Nuclear Factor κB Ligand), a protein involved in the formation, function, and survival of osteoclasts, the cells responsible for bone resorption.
Indications:- Osteoporosis: Used to reduce the risk of fractures in postmenopausal women with osteoporosis.
- Bone Loss: Indicated in patients undergoing certain cancer treatments that lead to bone loss.
- Giant Cell Tumor of Bone: For patients with unresectable or metastatic giant cell tumors.
Denosumab inhibits RANKL, preventing it from activating RANK on the surface of osteoclasts and their precursors. This leads to decreased osteoclast formation and activity, resulting in reduced bone resorption and increased bone mass.
Dosage and Administration:- Dosage: The typical dose is 120 mg administered subcutaneously once every month. Adjustments may be made based on individual patient needs.
- Administration: The injection should be given by a healthcare professional or as directed for self-administration.
- Common Side Effects: Back pain, joint pain, muscle pain, and injection site reactions (redness, swelling).
- Serious Side Effects: Hypocalcemia (low calcium levels), osteonecrosis of the jaw, and atypical femur fractures.
- Hypocalcemia: Patients with pre-existing low calcium levels should not use this medication without treatment.
- Severe Allergic Reactions: Known hypersensitivity to denosumab or any components of the formulation.
- Monitoring: Regular monitoring of calcium levels is recommended, especially during the initial phase of treatment.
- Jaw Health: Dental examinations should be conducted before starting therapy, and patients should maintain good oral hygiene.
Inform your healthcare provider about all medications you are taking, particularly calcium and vitamin D supplements, as well as other treatments for osteoporosis.
Storage Instructions:Store in the refrigerator at 2°C to 8°C (36°F to 46°F). Protect from light and do not freeze. Keep out of reach of children.
Patient Counseling:- Educate patients on the purpose of Esentra and its administration.
- Discuss potential side effects and the importance of regular follow-up appointments for monitoring.
- Advise patients to report any unusual symptoms, particularly related to bone pain or dental health.
Esentra (Denosumab) 120 mg Injection is an important treatment option for managing osteoporosis and other bone-related conditions. Always consult a healthcare provider for personalized medical advice and treatment plans.
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Lek Pamidol 370mg Iopamidol Injection
Product Price: Rs 750 / BoxGet Best Price
Product Brochure
Product Details:
| Concentration | 370 mgI/ml |
| Strength | 370 mg |
| Pack Size | 50 ml |
| Indication | CT contrast |
| Brand | Lek Pamidol |
| Packaging Size | 50ml in 1 vial |
| Composition (salt) | Lopamidol 370 mg |
| Manufactured By | J B Chemicals and Pharmaceuticals Ltd |
| Usage / Application | Diagnostic Agent |
Overview: Lek Pamidol is a contrast agent containing Iopamidol, used primarily in medical imaging procedures such as computed tomography (CT) scans and angiography. It helps enhance the visibility of internal structures in the body during imaging.
Indications:- Diagnostic Imaging: Used for various imaging studies, including:
- CT scans of the brain, chest, abdomen, and pelvis.
- Angiographic studies to visualize blood vessels.
- Intravenous Urography: Assists in imaging the urinary tract.
Iopamidol is an iodinated contrast agent that absorbs X-rays more effectively than surrounding tissues. This differential absorption creates clearer images of blood vessels and organs during imaging procedures.
Dosage and Administration:- Dosage: The dosage varies based on the specific procedure, patient's age, weight, and clinical situation. It is typically determined by the healthcare provider.
- Administration: Administered via intravenous injection or infusion, usually in a medical setting.
- Common Side Effects: Mild reactions may include:
- Nausea
- Vomiting
- Warmth or flushing
- Headache
- Serious Side Effects: Rare but can include:
- Allergic reactions (e.g., rash, difficulty breathing)
- Contrast-induced nephropathy (kidney damage)
- Thyroid dysfunction
- Hypersensitivity: Known allergy to Iopamidol or other iodinated contrast agents.
- Severe Kidney Impairment: Caution is advised in patients with renal dysfunction.
- Hydration: Patients may need adequate hydration before and after the procedure to reduce the risk of kidney-related side effects.
- Monitoring: Close monitoring during and after administration is essential, especially in patients with a history of allergies or kidney problems.
Inform your healthcare provider about all medications you are taking, especially those affecting kidney function or other contrast agents.
Storage Instructions:Store at room temperature, away from light and moisture. Follow any specific storage recommendations provided with the medication.
Patient Counseling:- Explain the purpose of Lek Pamidol and its role in diagnostic imaging.
- Discuss potential side effects and the importance of reporting any unusual symptoms.
- Advise patients to inform the healthcare team about any previous reactions to contrast agents.
Lek Pamidol (Iopamidol) 370 mg Injection is a valuable tool for enhancing imaging studies, providing clearer diagnostic information. Always consult healthcare professionals for personalized medical advice and treatment plans.
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Zoledronic Acid Injection
Product Price: Rs 2,500 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 4 mg |
| Dose/Strength | 4 mg |
| Brand | Zoldric |
| Manufacturer | Zee Laboratories Ltd |
| Packaging Size | 5 ml |
| Treatment | Osteoporosis |
| Brand Name | Zoldric |
Zoledronic Acid 4 mg/5 ml Injection (Zoldric 4 mg/5 ml Injection)
Indications:
Zoledronic acid is indicated for the treatment and prevention of osteoporosis in postmenopausal women, for the treatment of glucocorticoid-induced osteoporosis in men and women, and for the treatment of Paget's disease of bone. It is also used in patients with bone metastases from solid tumors and in multiple myeloma to prevent skeletal-related events.
Mechanism of Action:
Zoledronic acid is a bisphosphonate that inhibits osteoclast-mediated bone resorption, leading to a decrease in bone turnover and a subsequent increase in bone mineral density. This action helps to reduce the risk of fractures and other skeletal-related events.
Dosage and Administration:
- Dosage: The recommended dose of zoledronic acid is typically 4 mg administered as an intravenous infusion once a year for osteoporosis, or as directed for other indications.
- Administration: Administer via intravenous infusion over at least 15 minutes. Ensure proper hydration before administration.
Contraindications:
- Hypersensitivity to zoledronic acid or any component of the formulation.
- Patients with severe renal impairment (creatinine clearance <30 mL/min).
Warnings and Precautions:
- Renal Function: Monitor renal function prior to each dose and periodically during treatment. Dose adjustments may be necessary for patients with renal impairment.
- Hypocalcemia: Correct hypocalcemia prior to treatment, as zoledronic acid can exacerbate this condition.
- Osteonecrosis of the Jaw: Patients should be assessed for dental issues and receive appropriate dental care before initiating treatment.
Side Effects:
Common side effects may include:
- Fatigue
- Nausea
- Fever
- Bone pain
- Headache
Serious side effects can include:
- Renal impairment
- Osteonecrosis of the jaw
- Severe allergic reactions
Drug Interactions:
Zoledronic acid may interact with other medications that affect renal function or electrolyte balance. Patients should inform their healthcare provider of all medications they are taking.
Storage:
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Do not freeze.
Patient Counseling Information:
- Advise patients to report any signs of jaw pain, swelling, or dental problems, as these may indicate osteonecrosis of the jaw.
- Discuss the importance of adhering to the treatment schedule and attending regular follow-up appointments for monitoring renal function and bone health.
- Encourage patients to maintain adequate hydration and a balanced diet rich in calcium and vitamin D.
Conclusion:
Zoledronic acid is an effective treatment for osteoporosis and related conditions, providing patients with a means to improve bone health and reduce fracture risk. Continuous communication with healthcare providers is essential for managing potential side effects and ensuring optimal treatment outcomes. Always consult with a healthcare professional for personalized medical advice.
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Naloxone Injection (Nex 400mcg Injection)
Product Price: Rs 85 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 0.4 mg/ml |
| Packaging Size | 1X1 ml Vial |
| Pack Type | Vial |
| Indication | Opioid overdose |
| Packaging Type | Vial |
| Route of Administration | IV, IM, SC |
| Usage/Application | Opioid Toxicity |
| Composition | Naloxone 400mcg |
| Brand | Nex |
| Manufacturer | Neon Laboratories Ltd |
Overview: Naloxone is an opioid antagonist used to reverse the effects of opioid overdose, including respiratory depression and sedation. Nex 400 mcg Injection is typically administered in emergency situations to counteract life-threatening effects of opioids.
Uses:- Opioid Overdose: Primarily indicated for the emergency treatment of known or suspected opioid overdose, including respiratory depression, sedation, and hypotension.
- Typical Dose: The usual initial dose for adults is 0.4 to 2 mg, administered intravenously, intramuscularly, or subcutaneously. If there is no response after 2-3 minutes, additional doses may be given, up to a total of 10 mg. If no response occurs after that, reconsider the diagnosis.
- Administration: Can be given by healthcare professionals in emergency settings. Family members or caregivers may also receive training for administration in community settings.
Naloxone works by:
- Competitively binding to opioid receptors in the central nervous system, reversing the effects of opioid agonists. It displaces opioids from their receptors and inhibits their action.
- Common: Withdrawal symptoms in opioid-dependent individuals (e.g., agitation, nausea, vomiting).
- Serious: Allergic reactions, including rash, itching, or difficulty breathing. Seek immediate medical attention if these occur.
- Opioid Dependence: Use caution in patients who are opioid-dependent, as naloxone may precipitate withdrawal symptoms.
- Respiratory Monitoring: Continuous monitoring of respiratory function is recommended following administration.
- Known hypersensitivity to naloxone or any of its components.
- Naloxone may have interactions with other medications that affect the central nervous system. Always inform healthcare providers of all medications being taken.
- Store at room temperature, away from moisture and light. Keep out of reach of children.
- In emergency situations, naloxone should be administered as quickly as possible in suspected opioid overdoses.
- Educate caregivers and family members about recognizing signs of overdose and the importance of immediate medical attention following naloxone administration.
- Encourage patients to discuss their opioid use with healthcare providers to create a comprehensive pain management plan.
Nex 400 mcg Injection (Naloxone) is a critical medication for reversing opioid overdoses. Proper administration and monitoring are essential for safety and effectiveness. Always consult healthcare professionals for guidance on opioid management and overdose response.
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260mg Paclitaxel Injection
Product Price: Rs 2,500 / VialGet Best Price
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Product Details:
| Formulation Type | Nanoparticle Albumin-Bound |
| Pharmacopoeia Standard | IP |
| Strength | 260 mg |
| Pack Size | 43.4 ml |
| Brand | Pacget |
| Packaging Size | 16.7 ml in 1 vial |
| Composition | Paclitaxel 260 mg |
| Manufactured By | GLS Pharma Ltd. |
| Treatment | Breast disease |
Overview:
260mg Paclitaxel Injection contains Paclitaxel, a chemotherapy drug used to treat a variety of cancers, including ovarian, breast, non-small cell lung cancer, and Kaposi’s sarcoma in immunocompromised patients. Paclitaxel works by stabilizing microtubules, preventing their disassembly and halting cancer cell division. This leads to cell cycle arrest and ultimately cell death, particularly in rapidly dividing cancer cells.
Indications:
260mg Paclitaxel Injection is indicated for the treatment of:
- Ovarian Cancer: For advanced and recurrent cases.
- Breast Cancer: For early-stage and metastatic disease.
- Non-Small Cell Lung Cancer: For advanced stages.
- Kaposi’s Sarcoma: In patients with HIV/AIDS.
Mechanism of Action:
Paclitaxel stabilizes the microtubules inside cells, inhibiting their disassembly. This prevents proper mitosis, resulting in cell cycle arrest and inducing apoptosis (cell death), particularly in dividing tumor cells.
Dosage and Administration:
- Ovarian Cancer: 175 mg/m² intravenously over 3 hours every 3 weeks.
- Breast Cancer: 175 mg/m² intravenously over 3 hours every 3 weeks.
- Non-Small Cell Lung Cancer: 200 mg/m² intravenously over 3 hours every 3 weeks.
- Kaposi’s Sarcoma: 135 mg/m² intravenously over 3 hours every 3 weeks.
The 260mg vial is typically used based on body surface area (m²).
Side Effects:
Common: Hair loss, nausea, vomiting, fatigue, neutropenia.
Serious: Myelosuppression, neuropathy, allergic reactions, cardiotoxicity.
Precautions:
- Bone marrow suppression: Monitor blood counts regularly.
- Hypersensitivity: Premedication may be required to prevent allergic reactions.
- Liver function: Adjust dose for patients with liver impairment.
- Pregnancy: Contraindicated due to teratogenic risks.
Storage:
Store at room temperature (20°C–25°C). Protect from light and do not freeze.
Conclusion:
260mg Paclitaxel Injection is a vital treatment for various cancers, especially in cases of ovarian, breast, and lung cancers. Regular monitoring of blood counts and liver function is necessary to manage potential side effects.
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Nitroplus Nitroglycerin 25MG injection
Product Price: Rs 390 / PieceGet Best Price
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Product Details:
| Strength | 25 mg |
| Vial Volume | 5 ml |
| Packaging Type | Vial |
| Packaging Size | 5 ml |
| Manufacturer | Neon Laboratories Ltd |
| Brand | Nitroplus |
| Usage | Angina (heart-related chest pain) |
| Composition | Anidulafungin 100mg |
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Bortezomib Borviz 2.5 mg Injection
Product Price: Rs 2,500 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 2.5 mg |
| Dose/Strength | 2.5 mg |
| Brand | Borviz |
| Pack Size | Vial |
| Packaging Size | 1 Injection in 1 Vial |
| Composition | Bortezomib 2.5 mg |
| Brand Name | Borviz |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Treatment | Multiple Myeloma |
Overview:
Bortezomib 2.5mg Injection contains Bortezomib, a proteasome inhibitor used in the treatment of multiple myeloma and mantle cell lymphoma. It works by inhibiting the 26S proteasome, a key complex responsible for degrading unneeded or damaged proteins in cells. By blocking the proteasome, Bortezomib disrupts various cellular processes, leading to the accumulation of defective proteins, which induces cell death, particularly in cancer cells. This helps reduce tumor size and slows disease progression.
Indications:
Bortezomib 2.5mg Injection is primarily indicated for:
- Multiple Myeloma: In combination with other drugs for the treatment of relapsed or refractory multiple myeloma.
- Mantle Cell Lymphoma: For the treatment of relapsed or refractory mantle cell lymphoma after prior therapies.
Mechanism of Action:
Bortezomib selectively inhibits the proteasome, a cellular complex responsible for degrading proteins. This inhibition disrupts the regulation of important cellular processes, including cell cycle progression, apoptosis (programmed cell death), and DNA repair. By blocking the proteasome, Bortezomib induces cell stress, leading to the accumulation of misfolded proteins and the activation of cell death pathways, which specifically affect cancer cells.
Dosage and Administration:
- Multiple Myeloma: The usual dose is 1.3 mg/m² of body surface area, administered twice weekly for two weeks in a three-week cycle.
- Mantle Cell Lymphoma: Typically administered at 1.3 mg/m² for two cycles followed by maintenance therapy as needed.
- Administration: Bortezomib 2.5mg Injection is given intravenously (IV) or subcutaneously (SC). The injection is typically administered by a healthcare professional in a clinical setting.
Side Effects:
Common side effects include:
- Fatigue, nausea, diarrhea, and constipation.
- Peripheral neuropathy (numbness or tingling in hands/feet).
- Low blood counts (anemia, thrombocytopenia, neutropenia).
Serious side effects may include:
- Heart issues, including heart failure or arrhythmias.
- Liver damage: Regular liver function monitoring is required.
- Infections: Increased susceptibility to infections due to neutropenia and immunosuppression.
Precautions:
- Pregnancy: Bortezomib may cause harm to a fetus and should not be used during pregnancy.
- Heart Health: Use with caution in patients with existing heart disease or arrhythmias.
- Infections: Monitor for signs of infection, especially during prolonged treatment.
Storage:
Store Bortezomib 2.5mg Injection at room temperature (20°C to 25°C). Do not freeze. Protect from light and moisture.
Conclusion:
Bortezomib 2.5mg Injection is an effective treatment for multiple myeloma and mantle cell lymphoma, particularly in patients with relapsed or refractory disease. Regular monitoring of blood counts, heart function, and liver enzymes is important during treatment.
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Thiosol Thiopentone 500 mg Injection
Product Price: Rs 35 / VialGet Best Price
Product Brochure
Product Details:
| Strength | 500mg |
| Pack Type | Glass Vial |
| Form | Solution |
| Packaging Size | 1 Injection in 1 Vial |
| Brand Name | Thiosol |
| Manufactured By | Neon Laboratories Ltd |
| Composition | Thiopentone Sodium 500 mg |
| Treatment | Anesthesia |
Overview: Thiosol is an injectable formulation of thiopental sodium, a rapid-acting barbiturate used primarily as an anesthetic agent. It is known for its sedative and hypnotic properties, making it suitable for various medical procedures.
Indications for UseThiosol Thiopentone Injection is indicated for:
- Induction of Anesthesia: Commonly used for the rapid induction of general anesthesia in surgical procedures.
- Sedation: Provides sedation for patients undergoing procedures that may not require full anesthesia.
- Control of Seizures: Occasionally used in the management of status epilepticus to help control severe seizures.
Thiopental sodium acts by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) in the central nervous system. This leads to sedation and unconsciousness by depressing neural activity.
Dosage and Administration- Dosage: The specific dosage can vary based on the patient's age, weight, and clinical condition. Typical induction doses range from 3 to 5 mg/kg intravenously, with careful titration as needed.
- Administration Route: Administered via slow intravenous injection.
Common Side Effects:
- Drowsiness or dizziness
- Hypotension (low blood pressure)
- Respiratory depression
Serious Side Effects:
- Allergic reactions (rare)
- Cardiovascular instability, especially in patients with pre-existing conditions
- Use with caution in patients with a history of respiratory issues, cardiovascular problems, or known hypersensitivity to barbiturates.
- Continuous monitoring of vital signs is essential during and after administration.
- Ensure that resuscitation equipment is readily available, as thiopental can cause respiratory depression.
- Store at room temperature, away from light and moisture.
- Keep out of reach of children.
Patients should be advised to:
- Inform healthcare providers about any allergies, medical conditions, or medications they are taking prior to the procedure.
- Understand the recovery process after anesthesia, including the need for assistance after the procedure.
- Report any unusual symptoms during recovery.
Thiosol Thiopentone 500 mg Injection is an essential agent for inducing anesthesia and providing sedation. Proper administration and monitoring are critical to ensure safety and effectiveness during medical procedures. Always consult a healthcare professional for specific guidance regarding its use.
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Zolistra Zoledronic Acid 4mg Injectiion
Product Price: Rs 375 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 4 mg |
| Dose/Strength | 4 mg |
| Brand | Zolistra |
| Manufacturer | Celon Laborataries |
| Packaging Type | Vial |
| Composition | Zoledronic Acid 4mg Injectiion |
| Usage/Application | Hospital |
| Shelf Life | 24 to 36 Month |
| Brand Name | Zolistra |
Overview: Zoledronic acid is a bisphosphonate medication primarily used to treat various conditions related to bone health. It helps to inhibit bone resorption and is used in the management of osteoporosis, Paget's disease, and certain types of cancer that affect the bones.
Uses:- Osteoporosis: Used to increase bone mineral density and reduce the risk of fractures in postmenopausal women and men.
- Paget's Disease of Bone: Helps in the treatment of this chronic disorder that can result in enlarged and deformed bones.
- Bone Metastases: Used in patients with cancers such as breast cancer and prostate cancer to prevent skeletal-related events (e.g., fractures).
- Hypercalcemia of Malignancy: Used to treat elevated calcium levels in the blood due to cancer.
- Typical Dose: The standard dose for osteoporosis is usually 5 mg administered intravenously once a year. For other indications, the dose may vary; for example, 4 mg for treating hypercalcemia or bone metastases, given as a single infusion.
- Administration: Administered as an intravenous infusion over a period of at least 15 minutes. Adequate hydration is recommended before administration.
Zoledronic acid works by:
- Inhibiting osteoclast-mediated bone resorption, which decreases the rate of bone turnover and helps maintain bone density.
- Common: Fever, fatigue, nausea, vomiting, and bone pain.
- Serious: Risk of osteonecrosis of the jaw, renal impairment, and severe allergic reactions. Regular monitoring of kidney function is important.
- Renal Function: Assess renal function before administration, as zoledronic acid can affect kidney function. Avoid in patients with severe renal impairment.
- Dental Health: Patients should have a dental examination prior to treatment due to the risk of osteonecrosis of the jaw.
- Known hypersensitivity to zoledronic acid or any components of the formulation.
- Severe renal impairment (e.g., creatinine clearance < 30 mL/min).
- May interact with other medications affecting renal function. Always inform your healthcare provider of all medications being taken.
- Store at room temperature, away from light and moisture. Keep out of reach of children.
- Follow the prescribed treatment schedule and do not miss appointments for infusions.
- Stay well-hydrated before and after the infusion.
- Report any signs of severe side effects, such as jaw pain or swelling, difficulty in swallowing, or signs of kidney issues, to your healthcare provider.
Zolistra (Zoledronic Acid 4 mg Injection) is an effective treatment for managing bone health in various conditions, including osteoporosis and cancer-related bone issues. Proper administration, monitoring, and patient education are essential for optimal outcomes. Always consult your healthcare professional for personalized medical advice.
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Wosulin Biphasic Isophane Insulin Injection
Product Price: Rs 500 / BoxGet Best Price
Product Brochure
Product Details:
| Insulin Type | 30/70 Premix |
| Strength | 100 IU |
| Pack Size | 3 ml cartridge |
| Pack Type | 3 cartriges in 1 packet |
| Composition | Insulin Isophane (70%) + Human insulin (30%) |
| Brand Name | New Wosulin |
| Manufactured By | Wockhardt Ltd |
| Treatment | Diabetes |
Overview:
Wosulin Biphasic Isophane Insulin Injection contains Isophane insulin, a recombinant human insulin that combines both short-acting and intermediate-acting insulin to help regulate blood glucose levels in patients with diabetes mellitus. This biphasic formulation contains 30% regular insulin (short-acting) and 70% NPH (intermediate-acting) insulin, offering both rapid onset and prolonged action to manage postprandial and fasting blood glucose levels.
Indications:
Wosulin Biphasic Isophane Insulin Injection is indicated for:
- Type 1 Diabetes: Insulin-dependent diabetes, where the body does not produce enough insulin.
- Type 2 Diabetes: In patients with insufficient glycemic control on diet, exercise, and oral antidiabetic agents.
- Diabetic ketoacidosis: Acute complications of diabetes with elevated blood glucose and ketone levels.
Mechanism of Action:
Wosulin Biphasic Isophane Insulin contains a mixture of two types of insulin:
- Regular insulin (short-acting): Starts working within 30 minutes and peaks in 2-3 hours to control postprandial glucose levels.
- NPH insulin (intermediate-acting): Begins working within 1-2 hours and lasts for up to 12-18 hours, helping to control blood sugar levels between meals and overnight.
The combination provides both fast-acting control after meals and prolonged control throughout the day, helping maintain stable blood glucose levels.
Dosage and Administration:
- Dosage is individualized based on blood glucose levels, dietary habits, and physical activity.
- Typically administered subcutaneously in the thigh or abdomen.
- Timing: Usually injected 30 minutes before meals, but the exact timing depends on the specific needs of the patient.
- Dose adjustments: May be necessary based on blood glucose monitoring.
Side Effects:
Common side effects include:
- Hypoglycemia (low blood sugar), headache, dizziness.
- Weight gain, swelling (edema).
- Allergic reactions: Redness, itching, or swelling at the injection site.
Serious side effects may include:
- Severe hypoglycemia: Symptoms include confusion, seizures, or loss of consciousness.
- Lipodystrophy: Changes in fat distribution at the injection site.
- Insulin resistance.
Precautions:
- Hypoglycemia: Patients should monitor blood glucose regularly to prevent low blood sugar episodes, especially during physical activity.
- Renal and hepatic impairment: Dose adjustments may be necessary in patients with kidney or liver disorders.
- Pregnancy and breastfeeding: Consult a healthcare provider before use during pregnancy.
Storage:
- Store unopened vials or pens in the refrigerator at 2°C to 8°C.
- Once opened, it can be kept at room temperature for up to 4 weeks.
- Do not freeze.
Conclusion:
Wosulin Biphasic Isophane Insulin Injection is an effective insulin therapy for managing blood glucose levels in patients with Type 1 and Type 2 diabetes. Regular blood glucose monitoring, proper dose adjustment, and understanding the risk of hypoglycemia are essential to achieving optimal control.
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120mg Degapride Degarelix Injection
Product Price: Rs 17,000 / VialGet Best Price
Product Brochure
Product Details:
| Dosage Strength | 120 mg |
| Strength | 120 mg |
| Treatment | Advanced Prostate Cancer |
| Packaging Type | Box |
| Brand | Sun Pharma |
| Shelf Life | 3 Years |
| Form | Powder |
| Box Contains | 1 Vial |
| Usage | Used In The Treatment Of Advanced Prostate Cancer |
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Megval Melphalan 50mg injection
Product Price: Rs 1,500 / BottleGet Best Price
Product Brochure
Product Details:
| Dosage Form | Solution for Injection |
| Route Of Administration | Intravenous |
| Brand | Megval |
| Strength | 50 mg/vial |
| Packaging Size | Single Vial dose |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Treatment | Multiple myeloma, Ovarian cancer |
| Composition | Melphalan 50mg |
Megval Melphalan 50 mg Injection is a potent chemotherapy medication used primarily in the treatment of multiple myeloma and certain types of ovarian cancer. As an alkylating agent, it works by interfering with DNA replication, ultimately leading to the death of rapidly dividing cancer cells.
IndicationsMegval Melphalan is indicated for:
- Multiple Myeloma: Used as part of a combination chemotherapy regimen for patients with this type of blood cancer.
- Ovarian Cancer: Effective in treating patients with advanced ovarian tumors.
Melphalan acts by:
- Alkylation of DNA: It forms cross-links in DNA, which inhibits DNA replication and transcription, leading to cell death.
- Targeting Rapidly Dividing Cells: Particularly effective against cancer cells that divide quickly, disrupting their growth.
- Dosage: The typical dose of Megval Melphalan varies depending on the type of cancer being treated, the treatment protocol, and the patient’s health status. It is essential to follow the healthcare provider's instructions for dosage.
- Administration: Melphalan is administered intravenously. Careful monitoring during administration is crucial to manage potential adverse effects.
Megval Melphalan is contraindicated in:
- Hypersensitivity: Patients with known allergies to melphalan or any components of the formulation.
- Severe Bone Marrow Suppression: Not suitable for patients with significant bone marrow suppression.
- Myelosuppression: Monitor blood counts regularly, as melphalan can cause significant bone marrow suppression.
- Risk of Infections: Patients should be observed for signs of infection due to neutropenia.
- Potential for Extravasation: Ensure proper IV administration techniques to prevent tissue damage.
Common side effects may include:
- Nausea and vomiting
- Fatigue
- Bone marrow suppression (anemia, leukopenia, thrombocytopenia)
- Alopecia (hair loss)
Serious adverse effects can include:
- Severe allergic reactions
- Infections due to neutropenia
- Hemorrhage related to thrombocytopenia
Megval Melphalan may interact with other medications, particularly those that can also suppress bone marrow function. Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements.
Storage InstructionsStore Megval Melphalan 50 mg Injection at room temperature, protected from light and moisture. Follow specific storage guidelines as indicated on the product label.
Patient Counseling Information- Advise patients to report any side effects, especially symptoms of infection or bleeding.
- Discuss the importance of regular blood tests to monitor blood counts and manage potential side effects.
- Educate patients on supportive care measures to manage nausea and other side effects.
Megval Melphalan 50 mg Injection is an essential treatment option for multiple myeloma and certain ovarian cancers, effectively targeting rapidly dividing cells. Proper management and monitoring are crucial to optimize treatment outcomes and minimize adverse effects. Continuous communication between patients and healthcare providers is vital for successful cancer management.
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Zoleget 4 Zoledronic Acid Injection
Product Price: Rs 2,500 / PieceGet Best Price
Product Brochure
Product Details:
| Strength | 4 mg |
| Dose/Strength | 4 mg |
| Brand | Zoleget |
| Manufacturer | Gls Pharma Ltd |
| Packaging Size | 1 Injection in 1 vial |
| Composition | Zoledronic Acid 4 mg |
| Treatment | Postmenopausal osteoporosis, Pagets disease, Hypercalcemia (high level of calcium) in cancer |
| Brand Name | Zoleget |
Overview:
Zoleget 4 Injection contains Zoledronic Acid, a bisphosphonate used to treat osteoporosis, Paget's disease of bone, and bone complications associated with certain cancers (e.g., metastatic bone disease or hypercalcemia of malignancy). Zoledronic acid works by inhibiting osteoclast-mediated bone resorption, helping to increase bone density and reduce fracture risk. It also reduces calcium levels in the blood by inhibiting the release of calcium from bones.
Indications:
Zoleget 4 Injection is indicated for:
- Osteoporosis: Treatment and prevention of osteoporosis in postmenopausal women and men at risk for fractures.
- Paget’s disease of bone: Treatment to normalize bone turnover and reduce pain and fractures.
- Bone metastases: Prevention of skeletal-related events in patients with cancer metastasizing to bone (e.g., breast, prostate cancer).
- Hypercalcemia of malignancy: Treatment of high blood calcium levels due to cancer.
Mechanism of Action:
Zoledronic acid inhibits osteoclasts, the cells responsible for bone resorption. It binds to bone surfaces, reducing osteoclast activity and preventing excessive bone breakdown. This leads to increased bone mineral density, decreased fracture risk in osteoporotic patients, and prevention of bone complications in cancer patients. In hypercalcemia of malignancy, it helps lower elevated calcium levels by inhibiting the release of calcium from bone.
Dosage and Administration:
- Osteoporosis: 4 mg intravenously once a year.
- Paget’s disease: 5 mg intravenously once, with the possibility of a second dose after 6 months if necessary.
- Bone metastasis: 4 mg intravenously every 3-4 weeks, depending on the type of cancer and skeletal complications.
- Hypercalcemia of malignancy: 4 mg intravenously once, with adjustments based on calcium levels.
Zoleget 4 is administered as an intravenous infusion over at least 15 minutes. Ensure adequate hydration before infusion to reduce the risk of renal toxicity.
Side Effects:
Common side effects include:
- Fever, fatigue, and muscle or joint pain.
- Headache, nausea, and gastrointestinal discomfort.
Serious side effects may include:
- Osteonecrosis of the jaw: A rare but serious condition, often seen in cancer patients.
- Renal toxicity: Kidney function should be monitored before and after infusion.
- Hypocalcemia: Low calcium levels, particularly after the infusion.
Precautions:
- Renal function: Monitor renal function before and during treatment, especially in patients with pre-existing kidney problems.
- Dental care: Perform dental exams before treatment, as zoledronic acid can increase the risk of osteonecrosis of the jaw.
- Pregnancy and breastfeeding: Zoledronic acid is contraindicated in pregnancy and breastfeeding.
Storage:
Store at room temperature (20°C–25°C). Protect from light. Do not freeze.
Conclusion:
Zoleget 4 (Zoledronic Acid) Injection is an effective treatment for bone-related conditions like osteoporosis, Paget’s disease, and cancer-related bone complications. Regular monitoring of kidney function and calcium levels is essential, along with dental assessments to prevent rare side effects like osteonecrosis of the jaw.
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500mg PemPro Pemetrexed Injection
Product Price: Rs 2,800 / BoxGet Best Price
Product Brochure
Product Details:
| Dosage Form | Lyophilized Powder |
| Strength | 500 mg |
| Treatment | Non-Small Cell Lung Cancer |
| Pack Size | 50 ml |
| Pack Type | Box |
| Brand Name | Zydus |
| Usages | Used To Treat Non Small Cell Lung Cancer And Malignant Pleural Mesothelioma |
| Form | Injection |
Overview:
Pempro 500 mg Injection contains Pemetrexed, a folate antimetabolite chemotherapy drug used in the treatment of non-small cell lung cancer (NSCLC) and mesothelioma. Pemetrexed works by interfering with DNA synthesis, RNA synthesis, and cell division, ultimately inhibiting tumor growth. It is typically used as part of combination chemotherapy or as a maintenance therapy for patients with NSCLC.
- Non-Small Cell Lung Cancer (NSCLC): First-line treatment for locally advanced or metastatic NSCLC, usually in combination with cisplatin.
- Malignant Pleural Mesothelioma: Used in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma.
Pemetrexed is a multi-targeted antifolate that inhibits enzymes involved in folate metabolism, such as thymidylate synthase and dihydrofolate reductase. This inhibition prevents the synthesis of thymidine and purine nucleotides, essential building blocks for DNA and RNA. As a result, Pemetrexed blocks the growth and division of cancer cells, causing cell death, particularly in rapidly dividing tumor cells.
Dosage and Administration:- Non-Small Cell Lung Cancer (NSCLC): 500 mg/m² intravenously on day 1 of a 21-day cycle, in combination with cisplatin.
- Malignant Pleural Mesothelioma: 500 mg/m² intravenously on day 1 of a 21-day cycle, in combination with cisplatin.
- Maintenance therapy for NSCLC: Administer 500 mg/m² every 21 days, after initial treatment.
- Renal Impairment: Dosage adjustments may be required in patients with impaired renal function.
Administration:
Administer as an IV infusion over 10 minutes. Pre-medication with dexamethasone is recommended to reduce the risk of skin reactions.
Common: Fatigue, nausea, vomiting, anorexia, anemia, and neutropenia.
Serious: Myelosuppression, pulmonary toxicity, renal toxicity, and liver dysfunction.
Monitor: Complete blood counts, liver function tests, and renal function during treatment.
- Bone Marrow Suppression: Monitor for anemia, neutropenia, and thrombocytopenia.
- Pulmonary Toxicity: Be cautious in patients with pre-existing lung disease.
- Pregnancy and Lactation: Contraindicated during pregnancy and breastfeeding due to potential teratogenic effects.
Store vials at room temperature (15°C to 30°C). Protect from light and moisture. Keep out of reach of children.
Conclusion:Pempro (Pemetrexed 500 mg Injection) is an effective chemotherapy agent for treating NSCLC and malignant pleural mesothelioma. It works by inhibiting folate metabolism, preventing cancer cell growth and division. Regular monitoring of blood counts, liver, and kidney function is essential during treatment.
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Polyxx Polymyxin B 500000IU injection
Product Price: Rs 399 / VialGet Best Price
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Product Details:
| Strength | 500000 IU |
| Pack Size | 1 vial |
| Brand | Polyxx |
| Form | Injection |
| Pack Type | Bottle |
| Brand Name | Polyxx |
| Manufacturer | Celon Laboratories Ltd |
| Usages | Treatment of Severe bacterial infections |
| Packaging Type | Vial |
Overview: Polymyxin B is an antibiotic that belongs to the polymyxin class, primarily used to treat serious infections caused by gram-negative bacteria, particularly multidrug-resistant strains.
Indications:
- Bacterial Infections: Used for the treatment of infections caused by susceptible gram-negative organisms, including:
- Pseudomonas aeruginosa
- Escherichia coli
- Klebsiella pneumoniae
- Topical Infections: May also be used topically for localized infections.
Mechanism of Action: Polymyxin B disrupts the bacterial cell membrane by binding to the lipopolysaccharide component, leading to increased membrane permeability and ultimately causing cell death.
Dosage and Administration:
- Dosage: The typical adult dosage for serious infections may range from 1 to 2 mg/kg/day, divided into multiple doses. Specific dosing can vary based on the severity of the infection and local protocols.
- Administration: Administered intravenously or intramuscularly. Continuous monitoring of kidney function is recommended during treatment.
Contraindications:
- Hypersensitivity to polymyxin B or any component of the formulation.
- Caution in patients with pre-existing kidney issues, as the drug may lead to nephrotoxicity.
Warnings and Precautions:
- Monitor renal function regularly during treatment, as polymyxin B can cause kidney damage.
- Use with caution in patients with respiratory conditions.
Side Effects:
- Common: Nephrotoxicity, neurotoxicity (dizziness, headache), and gastrointestinal disturbances (nausea, vomiting).
- Serious: Risk of severe allergic reactions and respiratory distress.
Drug Interactions:
- May interact with other nephrotoxic medications. Always inform healthcare providers of all medications being taken.
Storage:
- Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from light. Keep out of reach of children.
Patient Counseling:
- Inform patients about the purpose of the injection and potential side effects.
- Advise them to report any unusual symptoms, particularly those related to kidney function or signs of allergic reactions.
Conclusion: Polyxx (Polymyxin B 500,000 IU Injection) is a critical antibiotic for treating serious infections caused by resistant gram-negative bacteria. Proper administration and monitoring are essential to ensure safety and effectiveness. Always consult a healthcare professional for personalized medical advice.
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Dexmedetomidine ( Dextomin 200mcg)
Product Price: Rs 550 / PieceGet Best Price
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Product Details:
| Strength | 200 mcg |
| Brand | Dextomid |
| Packaging Size | 2 ml |
| Composition | Dexmedetomidine 200 mcg |
| Brand Name | Dextomid |
| Manufacturer By | Neon Laboratories Ltd |
| Treatment | Sedation |
Overview:
Dexmedetomidine, marketed as Dextomin, is a sedative and analgesic agent used primarily for sedation in intensive care and procedural settings. It allows for sedation while enabling patients to remain responsive.
- Sedation for Mechanically Ventilated Patients: Used in the ICU for patients on ventilators.
- Procedural Sedation: Administered during short procedures to keep patients comfortable while allowing for some alertness.
- Postoperative Sedation: Helps in recovery by providing sedation after surgical procedures.
Dexmedetomidine selectively binds to alpha-2 adrenergic receptors in the central nervous system, leading to sedation and analgesia. This action reduces the release of norepinephrine, which helps calm patients while allowing them to respond to commands.
Dosage and Administration- Dosage: The initial infusion rate is usually between 0.2 to 0.7 mcg/kg/hour, tailored to patient needs and response.
- Administration: Administered via intravenous infusion, requiring continuous monitoring of the patient.
Common Side Effects:
- Hypotension (low blood pressure)
- Bradycardia (slow heart rate)
- Drowsiness
- Dry mouth
Serious Side Effects:
- Severe hypotension or bradycardia that may require intervention
- Respiratory depression (though rare)
Regular monitoring of vital signs is crucial, especially blood pressure and heart rate, due to potential cardiovascular effects.
Contraindications- Known hypersensitivity to dexmedetomidine or any of its components.
- Caution is advised for patients with significant cardiovascular disease or hypotension.
Inform your healthcare provider about all medications you are taking, particularly:
- CNS Depressants: Opioids and benzodiazepines, which may enhance sedative effects.
- Other medications that can affect blood pressure or heart rate.
Store Dextomin at room temperature, protected from light and moisture, and keep out of reach of children.
Patient Counseling Information- Usage: Emphasize adherence to prescribed doses and administration guidelines.
- Side Effects: Discuss potential side effects, especially those affecting alertness and cardiovascular stability.
- Discontinuation: Advise against stopping the medication suddenly without consulting a healthcare provider to avoid withdrawal symptoms.
Dextomin (dexmedetomidine 200 mcg) is an effective sedative for various medical scenarios. With careful administration and monitoring, it can significantly improve patient comfort and safety. Always consult a healthcare provider for personalized medical advice and treatment plans.
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