- Home
- »
- Our Products
- »
- Pharmaceutical Gel
Pharmaceutical Gel
Folitrax LP Methotrexate Gel
Minimum Order Quantity: 10 Box
Product Brochure
| Strength | 1% |
| Dose/Strength | 20 g |
| Packaging Size | 20 gm Gel in 1 Tube |
| Composition | Methotrexate 1% w/w |
| Brand | Folitrax LP |
| Manufacturer | Ipca Laboratories Ltd |
| Treatment | Psoriasis |
Folitrax LP Methotrexate Gel
Overview:
Folitrax LP Methotrexate Gel is a topical formulation of Methotrexate, an immunosuppressive drug commonly used to treat conditions like psoriasis, rheumatoid arthritis, and other autoimmune disorders. Methotrexate works by inhibiting the enzyme dihydrofolate reductase, which is involved in the production of DNA and cell division. By reducing the activity of immune cells, Methotrexate helps decrease inflammation and the overactive immune response that leads to conditions like psoriasis and rheumatoid arthritis.
Indications:
Folitrax LP Methotrexate Gel is primarily indicated for:
- Psoriasis: For the topical treatment of plaque psoriasis, especially in patients with localized lesions that do not respond to other treatments.
- Rheumatoid Arthritis: As an adjunctive therapy in the management of moderate to severe rheumatoid arthritis in adults, though more commonly used in oral or injectable forms.
- Other Autoimmune Disorders: It may be used for other off-label indications such as eczema or certain inflammatory skin conditions.
Mechanism of Action:
Methotrexate, as a folate antagonist, disrupts the production of purines and pyrimidines, which are essential for DNA synthesis and cell proliferation. By inhibiting cell division, Methotrexate reduces the rapid turnover of skin cells in psoriasis and suppresses the inflammatory processes in autoimmune conditions like rheumatoid arthritis.
Dosage and Administration:
- Recommended Dose: Folitrax LP Gel is typically applied once daily to the affected area or as directed by a healthcare professional.
- Application: Apply a thin layer of the gel to the lesion(s), and gently massage it into the skin.
- Administration: For topical use only. Avoid applying the gel on broken or infected skin. Wash hands thoroughly after use.
Side Effects:
Common side effects include:
- Skin irritation at the site of application (redness, burning, or itching)
- Dry skin or peeling
- Photosensitivity: Increased sensitivity to sunlight, leading to a higher risk of sunburn.
Serious side effects may include:
- Systemic toxicity (although rare with topical use): Symptoms can include nausea, fatigue, and liver enzyme abnormalities.
- Skin infections: If used on broken skin, the risk of infection may increase.
- Renal or hepatic dysfunction: Monitor kidney and liver function regularly if using for prolonged periods.
Precautions:
- Pregnancy and Breastfeeding: Methotrexate is contraindicated during pregnancy and breastfeeding due to potential teratogenic effects. It should be used only if clearly needed and under strict medical supervision.
- Liver and Kidney Function: Periodic monitoring of liver and kidney function is recommended, particularly with long-term use.
- Sun Protection: Patients should avoid excessive sun exposure and use sunscreen, as Methotrexate can increase sensitivity to sunlight.
Storage:
Store Folitrax LP Methotrexate Gel at room temperature (20°C to 25°C), away from light and moisture. Keep the cap tightly closed when not in use.
Conclusion:
Folitrax LP Methotrexate Gel is an effective treatment for managing localized psoriasis and other inflammatory skin conditions. It offers the benefit of targeted, topical therapy with fewer systemic side effects compared to oral or injectable Methotrexate. However, it is important to monitor for skin irritation, photosensitivity, and any potential liver or kidney issues during treatment.
Lignoheal Lignocaine Hydrochloride Gel I P 2% Gel
Minimum Order Quantity: 10 Box
Product Brochure
| Strength | 2% |
| Packaging Size | 30gm |
| Composition | Lignocaine Hydrochloride Gel I P 2% |
| Brand Name | Lingoheal 2% Gel |
| Manufacturer By | Healing Pharma |
| Treatment | Nearby Sedation (Numb tissues in a particular region) |
Overview: Lignoheal is a topical gel formulation containing 2% lignocaine (lidocaine hydrochloride), designed to provide localized pain relief. It is often used for various dermatological and medical procedures where temporary numbness is required.
Indications for UseLignoheal Gel is primarily indicated for:
- Local Anesthesia: Provides pain relief for minor surgical procedures, dental work, and other localized interventions.
- Skin Irritations: Can be used to relieve discomfort from conditions such as sunburn, insect bites, or minor burns.
Lignocaine works by blocking sodium channels in nerve membranes, preventing the transmission of pain signals. This results in a localized anesthetic effect, allowing for temporary numbness in the applied area.
Dosage and Administration- Application: Apply a thin layer of the gel to the affected area as directed by a healthcare professional.
- Frequency: Typically applied 2 to 3 times daily, or as needed, depending on the condition being treated.
Common Side Effects:
- Localized skin irritation or redness
- Tingling or burning sensation at the application site
Serious Side Effects:
- Allergic reactions (rare)
- Systemic effects if absorbed in significant amounts (e.g., dizziness, seizures) if used excessively.
- Avoid use on open wounds or broken skin unless directed by a healthcare provider.
- Use with caution in patients with known allergies to local anesthetics.
- Monitor for any signs of adverse reactions, especially during the first application.
- Store at room temperature, away from light and moisture.
- Keep out of reach of children.
Patients should be advised to:
- Follow the application instructions provided by their healthcare provider.
- Report any unusual symptoms or side effects, especially signs of severe irritation or allergic reactions.
- Avoid contact with eyes and mucous membranes.
Lignoheal Lignocaine Hydrochloride Gel I P 2% is an effective topical anesthetic for providing localized pain relief. Proper application and monitoring are essential for maximizing therapeutic benefits while minimizing risks. Always consult a healthcare professional for specific guidance regarding its use.
Dinoprostone Gel (Cerviprime 0.5mg Gel)
Minimum Order Quantity: 10 Piece
Product Brochure
| Strength | 0.5 mg |
| Packaging size | 3 gm |
| Composition | Dinoprostone (0.5mg) |
| Brand Name | Cerviprime 0.5mg Gel |
| Manufacturer | AstraZeneca |
| Uses | Induction of labour |