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Providing you the best range of spegra dolutegravir emtricitabine tenofovir alafenamide tablet, viraday tablet emtricitabine 200 mg + tenofovir disoproxil fumarate 300 mg + efavirenz 600 mg, ricovir em 200 mg/300 mg, trioday tablet (lamivudine 300 mg + tenofovir disoproxil fumarate 300 mg + efavirenz 600 mg), 1200mg telura tablet and vonaday tablet lamivudine & tenofovir disoproxil fumarate & efavirenz with effective & timely delivery.
Spegra Dolutegravir Emtricitabine Tenofovir Alafenamide Tablet
Product Price: Rs 2,000 / BottleGet Best Price
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Product Details:
| Dose Strength | 50 mg/200 mg/25 mg |
| Strength | 50 mg/200 mg/25 mg |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Dolutegravir 50 mg + Emtricitabine 200 mg + Tenofovir Alafenamide 25 mg |
| Brand Name | Spegra Tablets |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Treatment | HIV-1 Infection |
Spegra Dolutegravir Emtricitabine Tenofovir Alafenamide Tablet
Overview:
Spegra is a combination medication that contains Dolutegravir, Emtricitabine, and Tenofovir Alafenamide. It is used for the treatment of HIV-1 infection in adults and pediatric patients. Dolutegravir is an integrase strand transfer inhibitor (INSTI), Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI), and Tenofovir Alafenamide is a nucleotide reverse transcriptase inhibitor (NTRI). This combination works by preventing the replication of the HIV virus in the body, thus reducing the viral load and increasing the number of CD4 cells (immune cells).
Indications:
Spegra is indicated for:
- HIV-1 infection: For the treatment of HIV-1 in adults and children (weighing at least 25 kg) as part of a combination therapy.
Mechanism of Action:
- Dolutegravir: Inhibits the integrase enzyme, preventing viral DNA from integrating into the host cell's genome.
- Emtricitabine: Inhibits reverse transcriptase, preventing the transcription of viral RNA into DNA.
- Tenofovir Alafenamide: Inhibits reverse transcriptase, preventing the replication of viral RNA.
This combined action suppresses the HIV virus and reduces the chances of developing resistance to treatment.
Dosage and Administration:
- Recommended Dose: The usual dose of Spegra is one tablet once daily, taken orally with or without food.
- Missed Dose: If a dose is missed, take it as soon as possible unless it's almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects may include:
- Headache, diarrhea, nausea, and fatigue.
- Serious side effects may include:
- Liver issues: Hepatitis, jaundice.
- Renal issues: Kidney dysfunction or increased creatinine levels.
- Hypersensitivity reactions: Rashes or breathing difficulties.
Precautions:
- Hepatic Impairment: Caution is needed in patients with liver disease. Liver function should be monitored.
- Renal Impairment: Regular kidney function tests are recommended.
- Pregnancy: Spegra is not recommended during pregnancy unless the benefit outweighs the risk. Use appropriate contraception.
Storage:
Store Spegra tablets at room temperature (15°C to 30°C), away from moisture and heat. Keep out of reach of children.
Conclusion:
Spegra is an effective once-daily combination therapy for managing HIV-1 infection, helping reduce viral load and improving immune function. Regular monitoring for side effects, particularly liver and renal function, is necessary for safe use.
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Viraday Tablet Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg
Product Price: Rs 1,200 / BottleGet Best Price
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Product Details:
| Dose/Strength | 200mg/300mg/600mg |
| Composition | Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg |
| Packaging Size | 1x30Tablets |
| Strength | 200 mg/300 mg/600 mg |
| Brand Name | Viraday Tablet |
| Manufacturers | Cipla Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Viraday 110mg Tablet
Overview: Viraday is a combination medication used primarily in the treatment of HIV-1 infection. It contains three active ingredients: Tenofovir Disoproxil Fumarate (300 mg), Lamivudine (150 mg), and Efavirenz (600 mg). This combination works by inhibiting the reverse transcriptase enzyme, a key enzyme that HIV uses to replicate itself. By blocking this enzyme, Viraday helps lower the amount of HIV in the blood, improve the immune system's ability to fight infections, and reduce the risk of transmitting HIV to others.
Indications: Viraday 110mg Tablet is indicated for:
- HIV-1 Infection: Used as a part of combination antiretroviral therapy (ART) for adults and adolescents (aged 12 years or older) who are infected with HIV-1.
Mechanism of Action:
- Tenofovir Disoproxil Fumarate (TDF): An NRTI (nucleoside reverse transcriptase inhibitor) that inhibits reverse transcriptase, reducing HIV replication.
- Lamivudine (3TC): An NRTI that also blocks reverse transcriptase and prevents HIV replication.
- Efavirenz (EFV): A non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to the reverse transcriptase enzyme, further inhibiting viral replication.
Together, these medications work synergistically to suppress viral replication and improve immune function in HIV-infected patients.
Dosage and Administration:
- Recommended Dose: 1 tablet (110 mg) daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It's advised to take it at the same time every day for optimal results.
Side Effects:
- Common Side Effects: Dizziness, headache, nausea, fatigue, insomnia, and rash.
- Serious Side Effects: Liver toxicity, depression, suicidal thoughts, and severe allergic reactions. Regular monitoring of liver function is recommended.
Precautions:
- Liver Disease: Not recommended for patients with severe liver disease.
- Pregnancy: Avoid use during the first trimester due to potential harm to the fetus. Consult your doctor.
- Kidney Function: Regular kidney function tests are necessary.
Storage: Store at room temperature (15°C to 30°C), in a dry place, away from moisture and heat.
Conclusion: Viraday 110mg Tablet is an effective HIV treatment that combines three antiretroviral drugs to suppress viral replication. Regular monitoring of liver function and kidney health is recommended during treatment.
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Ricovir EM 200 mg/300 mg
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 200 mg/300 mg |
| Composition | Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Strength | 200 mg/300 mg |
| Brand Name | Ricovir EM |
| Manufacturerd By | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | HIV Infection |
Ricovir EM 200mg/300mg Tablet
Overview: Ricovir EM is a combination antiretroviral medication used to treat HIV-1 infection. It contains two active ingredients: Lamivudine (200 mg) and Emtricitabine (300 mg). Both drugs belong to the class of nucleoside reverse transcriptase inhibitors (NRTIs), which help block the replication of the HIV virus. By reducing the amount of HIV in the blood and improving the immune system, Ricovir EM plays a crucial role in managing HIV infection.
Indications: Ricovir EM 200 mg/300 mg Tablet is indicated for:
- HIV-1 Infection: It is used as a part of combination antiretroviral therapy (ART) for the treatment of HIV-1 infection in adults and pediatric patients who weigh at least 35 kg.
Mechanism of Action:
- Lamivudine (200 mg): A nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, thereby preventing HIV from replicating in the body.
- Emtricitabine (300 mg): Similar to lamivudine, emtricitabine blocks the reverse transcriptase enzyme, preventing the replication of the HIV virus.
Together, these medications help control the HIV virus, reducing viral load and enhancing the effectiveness of the immune system.
Dosage and Administration:
- Recommended Dose: One tablet of Ricovir EM 200 mg/300 mg once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water, at the same time each day for best results.
Side Effects:
- Common Side Effects: Headache, fatigue, nausea, diarrhea, and dizziness.
- Serious Side Effects: Lactic acidosis, liver toxicity, pancreatitis, and severe allergic reactions. Liver function should be monitored regularly.
Precautions:
- Liver Disease: Caution in patients with a history of liver problems.
- Pregnancy: Consult a healthcare provider before use during pregnancy.
- Kidney Function: Kidney function should be monitored during treatment.
Storage: Store Ricovir EM 200 mg/300 mg tablets at room temperature (15°C to 30°C), away from moisture and direct sunlight.
Conclusion: Ricovir EM 200 mg/300 mg Tablet is an effective combination treatment for HIV-1 infection, helping to suppress the virus and support the immune system. Regular monitoring of liver and kidney function is recommended during treatment.
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Trioday Tablet (Lamivudine 300 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg)
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/300 mg/600 mg |
| Composition | Efavirenz 600 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Strength | 300 mg/300 mg/600 mg |
| Brand Name | Trioday Tablet |
| Manufactured | Cipla Ltd |
| Treatment | HIV infection |
Trioday 1200mg Tablet
Overview: Trioday is a combination medication containing Tenofovir Disoproxil Fumarate (300 mg), Emtricitabine (200 mg), and Efavirenz (600 mg). It is used to treat HIV-1 infection and to prevent the progression of the virus in individuals diagnosed with HIV. The three active ingredients in Trioday work together to inhibit the replication of HIV, thereby helping to reduce the viral load and improve immune function in people living with HIV.
Indications: Trioday 1200mg Tablet is indicated for:
- HIV-1 Infection: As a part of a combination antiretroviral regimen in adults and children who weigh at least 35 kg.
Mechanism of Action:
- Tenofovir: A nucleoside reverse transcriptase inhibitor (NRTI) that blocks reverse transcriptase, the enzyme responsible for converting viral RNA into DNA, preventing viral replication.
- Emtricitabine: Another NRTI that works in a similar way to Tenofovir, further inhibiting reverse transcriptase and suppressing HIV replication.
- Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to the reverse transcriptase enzyme and prevents it from functioning, contributing to the inhibition of HIV replication.
Dosage and Administration:
- Recommended Dose: One Trioday 1200mg tablet once daily, taken orally.
- Administration: The tablet should be swallowed whole with or without food. It is recommended to take it at the same time each day.
Side Effects:
- Common Side Effects: Rash, dizziness, headache, nausea, fatigue, and diarrhea.
- Serious Side Effects: Liver toxicity, kidney problems, severe allergic reactions, and central nervous system effects such as depression or vivid dreams.
Precautions:
- Liver Disease: Regular liver function tests are recommended for patients with a history of liver problems.
- Pregnancy: Use during pregnancy should be considered only when necessary; consult a healthcare provider.
- Drug Interactions: Inform the doctor of any other medications being taken to avoid interactions.
Storage: Store Trioday 1200mg tablet at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion: Trioday 1200mg Tablet is an effective combination treatment for managing HIV-1 infection. It should be taken as prescribed, with regular medical check-ups for monitoring any side effects.
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1200mg Telura Tablet
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/300 mg/600 mg |
| Strength | 300 mg/300 mg/600 mg |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Lamivudine 300mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg |
| Brand Name | Telura Tablet |
| Manufacturers | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | Chronic hepatitis B virus (HBV) Infection |
Telura 1200mg Tablet
Overview:Telura is a medication that contains Telbivudine (1200 mg), an antiviral drug used primarily in the treatment of chronic hepatitis B (HBV). Telbivudine is a nucleoside analogue reverse transcriptase inhibitor (NRTI). It works by inhibiting the replication of the hepatitis B virus by blocking the reverse transcriptase enzyme, which is essential for the virus to replicate its genetic material.
Telura 1200mg tablets are specifically used to reduce the viral load in patients with chronic hepatitis B, improve liver function, and decrease the risk of complications like cirrhosis and liver cancer.
Indications:Telura 1200 mg Tablet is indicated for:
- Chronic Hepatitis B (HBV): Treatment of chronic hepatitis B infection in adults with evidence of active viral replication and liver damage.
Telbivudine, the active ingredient in Telura, works by inhibiting hepatitis B virus reverse transcriptase. This enzyme is required by HBV to replicate its viral genome. By blocking this enzyme, Telbivudine prevents the virus from replicating, thereby reducing the viral load, improving liver function, and slowing the progression of liver disease associated with chronic HBV infection.
Dosage and Administration:- Recommended Dose: The typical dose of Telura is 1200 mg once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It is important to take Telura at the same time each day to maintain consistent drug levels in the body.
-
Common Side Effects:
- Headache
- Fatigue
- Nausea
- Diarrhea
- Upper respiratory tract infections
-
Serious Side Effects:
- Lactic acidosis (a buildup of lactic acid in the blood)
- Hepatomegaly (enlarged liver) and steatosis (fatty liver)
- Peripheral neuropathy (nerve damage, causing pain, tingling, or weakness)
- Muscle pain or weakness (myopathy)
Regular monitoring of liver function and kidney health is recommended to detect any adverse reactions early.
- Kidney Impairment: Telura should be used with caution in patients with pre-existing kidney disease, as renal function may be impacted. Regular monitoring of kidney function (serum creatinine, eGFR) is advised.
- Liver Disease: Patients with severe liver dysfunction or cirrhosis should be monitored closely during treatment.
- Pregnancy: Discuss the use of Telura with your doctor if you are pregnant or planning to become pregnant. The medication is classified as Pregnancy Category C, meaning the risk to the fetus cannot be ruled out.
- Breastfeeding: Telbivudine is excreted in breast milk; therefore, consult your healthcare provider before breastfeeding.
Store Telura 1200 mg tablets at room temperature (15°C to 30°C), away from light and moisture. Keep the medication in its original packaging and out of reach of children.
Conclusion:Telura 1200mg Tablet is an effective treatment for chronic hepatitis B (HBV). It helps reduce the viral load and improves liver function, decreasing the risk of complications like cirrhosis or liver cancer. Adherence to the prescribed dosage, regular monitoring of liver and kidney function, and consultation with your healthcare provider are essential for optimal treatment outcomes.
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Vonaday Tablet Lamivudine & Tenofovir Disoproxil Fumarate & Efavirenz
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/300 mg/600 mg |
| Strength | 300 mg/300 mg/600 mg |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Lamivudine 300 mg & Tenofovir disoproxil fumarate 300 mg & Efavirenz 600 mg |
| Brand Name | Vonaday Tablets |
| Manufacturers | Cipla Ltd |
| Treatment | HIV infection |
Vonaday 1200mg Tablet
Overview: Vonaday is a combination medication used primarily for the treatment of HIV-1 infection. It contains three active ingredients: Tenofovir Disoproxil Fumarate (300 mg), Emtricitabine (200 mg), and Efavirenz (600 mg). This combination therapy helps control the replication of HIV in the body by inhibiting the activity of HIV enzymes essential for its replication.
Indications: Vonaday 1200mg Tablet is indicated for:
- HIV-1 Infection: For adults and pediatric patients (weighing at least 35 kg) as part of a combination antiretroviral regimen.
Mechanism of Action:
- Tenofovir: A nucleoside reverse transcriptase inhibitor (NRTI), which blocks reverse transcriptase, preventing the conversion of viral RNA into DNA and inhibiting viral replication.
- Emtricitabine: Another NRTI that works by inhibiting the reverse transcriptase enzyme, reducing the ability of the virus to multiply.
- Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to and deactivates the reverse transcriptase enzyme, further hindering HIV replication.
Dosage and Administration:
- Recommended Dose: Take one Vonaday 1200mg tablet once daily, preferably at the same time each day.
- Administration: Swallow the tablet whole with or without food. Ensure proper hydration and consistency in dosing.
Side Effects:
- Common Side Effects: Nausea, headache, dizziness, fatigue, insomnia, and rash.
- Serious Side Effects: Hepatotoxicity, renal impairment, depression, severe allergic reactions, and neuropsychiatric symptoms such as vivid dreams or mood changes.
Precautions:
- Liver Disease: Monitor liver function, especially for patients with pre-existing liver conditions.
- Pregnancy and Breastfeeding: Consult your healthcare provider before using Vonaday during pregnancy or breastfeeding.
- Drug Interactions: Be aware of potential interactions with other medications. Inform your doctor about all other treatments.
Storage: Store Vonaday 1200mg tablet at room temperature (15°C to 30°C), away from moisture and direct light. Keep out of reach of children.
Conclusion: Vonaday 1200mg Tablet is a highly effective treatment for managing HIV-1 infection. Proper adherence to the prescribed regimen and regular medical monitoring are important for achieving optimal outcomes.
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Vemlidy Tenofovir Alafenamide 25 mg Tablets
Product Price: Rs 1,200 / BottleGet Best Price
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Product Details:
| Dose Strength | 25 mg |
| Composition | Tenofovir Alafenamide 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Brand Name | Vemlidy Tablets |
| Manufacturer | Gilead Science Ltd |
| Treatment | Ongoing hepatitis B infection (HBV) contamination |
Vemlidy Tenofovir Alafenamide 25mg Tablets
Overview: Vemlidy (Tenofovir Alafenamide) is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults and pediatric patients aged 12 years and older. It is a nucleotide reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HBV virus. By blocking this enzyme, Tenofovir Alafenamide reduces the viral load in the body, helping to prevent liver damage, cirrhosis, and liver failure.
Indications: Vemlidy 25mg is indicated for the treatment of chronic hepatitis B (HBV) in adult and pediatric patients who are HBV DNA positive and have compensated liver disease. It is used to reduce the amount of the virus in the blood and to improve liver function. Vemlidy is not a cure for HBV but can help control the infection over time.
Mechanism of Action: Tenofovir Alafenamide is a prodrug of Tenofovir, which is phosphorylated inside the cell to its active form. It inhibits the reverse transcriptase enzyme of the HBV virus, preventing viral replication. This reduces the amount of HBV in the liver and blood, improving liver function and decreasing the risk of liver damage.
Dosage and Administration:
- Recommended dose: One 25mg tablet once daily, with or without food.
- Administration: Swallow the tablet whole with water. Do not crush or chew.
- Missed dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose.
Side Effects:
- Common side effects: Headache, fatigue, nausea, and abdominal pain.
- Serious side effects: Renal impairment, lactic acidosis, hepatomegaly, and steatosis. Regular monitoring of kidney function is recommended.
Precautions:
- Renal function: Regular monitoring of renal function and serum phosphate is advised, especially in patients with pre-existing kidney conditions.
- Pregnancy: Consult with a healthcare provider before use during pregnancy or breastfeeding.
Storage: Store Vemlidy at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion: Vemlidy 25mg is an effective treatment for chronic hepatitis B. With regular monitoring, it can significantly reduce viral load and improve liver function in patients with HBV infection.
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Valten 300 mg Tablet
Product Price: Rs 450 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg |
| Composition | Tenofovir Disoproxil Fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Brand Name | Valten 300 mg |
| Manufacturers | Wockhardt Ltd |
| Treatment | Chronic Hepatitis B Virus (HBV) Infection |
Valten 300mg Tablet
Overview: Valten 300mg Tablet is a medication primarily used for the management of hypertension (high blood pressure) and heart failure. It contains Valsartan, an angiotensin II receptor antagonist (ARB). Valsartan works by blocking the action of angiotensin II, a substance that narrows blood vessels and raises blood pressure. By blocking this action, Valten helps relax blood vessels, lower blood pressure, and reduce the risk of complications like stroke, heart attack, and kidney problems.
Indications: Valten 300mg Tablets are indicated for:
- Hypertension: To lower blood pressure in adults and children over 6 years old.
- Heart Failure: In patients with symptomatic heart failure to improve survival and reduce hospitalizations.
- Post-Heart Attack: For the treatment of heart attack patients with reduced left ventricular function.
Mechanism of Action: Valsartan, the active ingredient in Valten, is an angiotensin II receptor blocker (ARB). It binds to and blocks the angiotensin II receptors, thereby inhibiting the constriction of blood vessels. This leads to vasodilation (widening of blood vessels), which reduces blood pressure and helps the heart pump more efficiently.
Dosage and Administration:
- Hypertension: The typical dose is 80-320 mg once daily, depending on the severity of the condition.
- Heart Failure and Post-Heart Attack: The usual dose is 40-160 mg once daily, titrated based on patient tolerance.
- Administration: Take Valten 300mg Tablet orally, with or without food, at the same time each day.
Side Effects:
- Common Side Effects: Dizziness, headache, fatigue, and abdominal pain.
- Serious Side Effects: Low blood pressure, elevated potassium levels (hyperkalemia), kidney problems, and allergic reactions.
Precautions:
- Kidney Function: Monitor renal function regularly during treatment.
- Pregnancy and Breastfeeding: Valten is contraindicated during pregnancy, especially in the second and third trimesters, as it may harm the fetus.
Storage: Store Valten 300mg Tablet at room temperature (20°C to 25°C), away from moisture and light.
Conclusion: Valten 300mg Tablet is an effective treatment for hypertension, heart failure, and post-heart attack management. It works by relaxing blood vessels and lowering blood pressure, helping reduce the risk of cardiovascular events and improving heart function.
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Velpaclear 400 Mg/100mg Tablets
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Strength | 400 mg+ 100 mg |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Velpatasvir 100 mg + Sofosbuvir 400 mg |
| Brand | Velpaclear 100 mg/400 mg tablet |
| Manufactured By | Abbott |
| Treatment Of | Chronic hepatitis C virus (HCV) infection |
Velpaclear 400 mg/100 mg Tablets
Overview:
Velpaclear is a combination antiviral medication containing Sofosbuvir (400 mg) and Velpatasvir (100 mg). It is used for the treatment of chronic hepatitis C virus (HCV) infection in adults. Sofosbuvir is a nucleoside analog that inhibits HCV replication, while Velpatasvir is a NS5A inhibitor that interferes with the HCV lifecycle. Together, these two components work to reduce the viral load and improve the chances of curing hepatitis C.
Indications:
Velpaclear is indicated for the treatment of chronic hepatitis C virus infection in adult patients. It is effective against HCV genotypes 1, 2, 3, 4, 5, and 6 and can be used for treatment-naive patients or those who have previously failed other treatments.
Mechanism of Action:
- Sofosbuvir blocks the NS5B RNA-dependent RNA polymerase enzyme, which is necessary for the replication of the hepatitis C virus.
- Velpatasvir targets the NS5A protein, preventing the virus from assembling and releasing new virions. By combining both, Velpaclear effectively suppresses HCV replication.
Dosage and Administration:
- The typical dosage of Velpaclear is one tablet daily, taken with or without food.
- Treatment duration is generally 12 weeks, but may vary based on HCV genotype, prior treatment history, and liver function.
Side Effects:
- Common side effects: Fatigue, headache, nausea, and diarrhea.
- Serious side effects: Liver enzyme abnormalities, risk of hepatitis B reactivation in co-infected individuals, and allergic reactions.
Precautions:
- Hepatitis B screening: Before starting treatment, patients should be tested for hepatitis B infection.
- Pregnancy: Velpaclear should not be used during pregnancy unless the benefits outweigh the risks.
- Drug interactions: Velpaclear may interact with certain other medications, so it's important to discuss all medications with your healthcare provider.
Storage:
Store Velpaclear tablets at room temperature (20°C to 25°C). Keep the medication in its original packaging and protect from moisture.
Conclusion:
Velpaclear 400 mg/100 mg tablets are an effective treatment for chronic hepatitis C, improving viral suppression and reducing the likelihood of disease progression. Regular monitoring and follow-up are essential during treatment.
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Trustiva 300mg/600mg/200mg Tablet
Product Price: Rs 3,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/600 mg/200 mg |
| Strength | 300 mg/600 mg/200 mg |
| Pack Size | 30 Capsules in 1 Bottle |
| Composition (salt) | Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg |
| Brand Name | Trustiva 300 mg/600 mg/200 mg Tablet |
| Manufactured | Hetero Drugs Ltd |
| Treatment | HIV infection |
Trustiva 300mg/600mg/200mg Tablet
Overview:
Trustiva is a combination antiretroviral medication containing 300 mg of Tenofovir disoproxil fumarate, 600 mg of Efavirenz, and 200 mg of Emtricitabine. It is used in the treatment of HIV-1 infection, either alone or in combination with other antiretroviral agents. This fixed-dose combination helps reduce the viral load, improves immune function, and prevents the progression of HIV to AIDS. It works by inhibiting different steps in the HIV replication cycle: Tenofovir and Emtricitabine are nucleotide reverse transcriptase inhibitors (NRTIs), while Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Indications:
Trustiva 300mg/600mg/200mg Tablet is indicated for:
- HIV-1 Infection: For the treatment of HIV-1 in adults and children over 12 years of age.
- Combination Therapy: It is used in combination with other antiretrovirals as part of a multi-drug regimen for optimal viral suppression.
Mechanism of Action:
- Tenofovir: Blocks the HIV reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA.
- Emtricitabine: Similar to Tenofovir, it inhibits reverse transcriptase, preventing viral replication.
- Efavirenz: Non-competitively binds to reverse transcriptase, preventing it from synthesizing HIV DNA, thus halting viral replication.
Dosage and Administration:
- Recommended Dose: The usual adult dose is one tablet once daily, taken with or without food.
- Administration: Swallow the tablet whole with water.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it is almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Headache, nausea, dizziness, fatigue, and sleep disturbances.
Serious side effects may include: - Liver toxicity: Hepatitis or liver enzyme abnormalities.
- Psychiatric effects: Mood changes, depression, and suicidal thoughts, especially with Efavirenz.
- Rash: Severe rashes can develop, requiring immediate medical attention.
Precautions:
- Liver disease: Caution is required for patients with liver problems, and liver enzymes should be monitored regularly.
- Pregnancy: Efavirenz is contraindicated in pregnancy during the first trimester. The combination may still be used in later stages, but only under a doctor’s supervision.
Monitoring:
- Liver function: Regular liver tests are necessary.
- Renal function: Tenofovir can affect kidney function, so monitoring is required.
- Psychiatric effects: Regular mental health check-ups are important.
Storage:
Store Trustiva at room temperature (20°C to 25°C), away from moisture and heat. Keep the tablet in its original container and out of reach of children.
Conclusion:
Trustiva 300mg/600mg/200mg Tablet is an effective HIV treatment that combines three antiretroviral agents into one tablet. It helps reduce viral load, improve immune function, and prevent HIV progression. Patients should be monitored for potential side effects, particularly related to liver and mental health.
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Tenofovir Alafenamide Tablet (Tenohep AF 25 mg Tablet)
Product Price: Rs 1,000 / BottleGet Best Price
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Product Details:
| Dose Strength | 25 mg |
| Composition | Tenofovir Alafenamide 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Brand Name | Tenohep AF Tablet |
| Manufacturer | Zydus Cadila |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Tenofovir Alafenamide Tablet
Overview: Tenofovir Alafenamide (TAF) is an antiretroviral medication used in the treatment of HIV-1 infection and chronic hepatitis B. It is a prodrug of tenofovir, designed to deliver higher concentrations of the active drug to target cells while minimizing the impact on kidney and bone health. TAF is a nucleoside reverse transcriptase inhibitor (NRTI), which works by blocking the reverse transcriptase enzyme, essential for the replication of HIV and hepatitis B viruses. TAF is typically used as part of a combination therapy.
Indications:
- HIV-1 infection: Used in combination with other antiretroviral agents to manage HIV-1 in adults and children (weighing at least 25 kg).
- Chronic Hepatitis B: For the treatment of chronic hepatitis B in adults with evidence of active viral replication.
Mechanism of Action: TAF is metabolized into the active compound tenofovir, which inhibits reverse transcriptase. This prevents the conversion of viral RNA into DNA, thus halting viral replication. Compared to its predecessor, Tenofovir Disoproxil Fumarate (TDF), TAF offers a more targeted approach, allowing lower doses and reducing potential side effects.
Dosage and Administration:
- Recommended Dose: The typical dose is 25 mg once daily.
- Administration: Take one tablet daily, with or without food. The tablet should not be chewed or crushed.
- Renal Adjustment: Caution is advised in patients with renal impairment; dose adjustments may be needed.
Side Effects:
- Common Side Effects: Nausea, headache, fatigue, diarrhea, and dizziness.
- Serious Side Effects: Kidney toxicity, bone mineral density loss, lactic acidosis, and liver toxicity.
Precautions:
- Renal Function: Regular monitoring of kidney function is recommended.
- Liver Disease: In patients with hepatitis B, liver enzymes should be monitored regularly.
- Pregnancy: Use during pregnancy only if clearly needed; consult a healthcare provider.
Storage: Store Tenofovir Alafenamide at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion: Tenofovir Alafenamide (TAF) is an effective and safer alternative to previous formulations of tenofovir. It is key in the management of HIV and hepatitis B, offering patients a more tolerable treatment option with regular monitoring for side effects.
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Tenolam Tenofovir Disoproxil Fumarate LamivudineTablets
Product Price: Rs 1,000 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg |
| Composition | Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Brand Name | Tenolam Tablets |
| Manufacturers | Hetero Drugs Ltd |
| Treatment | HIV infection |
Tenolam Tenofovir Disoproxil Fumarate and Lamivudine Tablets
Overview:Tenolam combines Tenofovir Disoproxil Fumarate (300 mg) and Lamivudine (150 mg), two antiviral medications used to treat HIV-1 infection and chronic hepatitis B (HBV). Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI), and Lamivudine is also an NRTI. Together, they work by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of HIV and HBV. By blocking viral replication, Tenolam reduces the viral load, improves immune function in HIV patients, and helps manage chronic hepatitis B.
Indications:Tenolam Tablets are indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen for adults and children.
- Chronic Hepatitis B (HBV): For adults with chronic HBV infection who have evidence of active viral replication and liver damage.
Tenofovir Disoproxil Fumarate is converted into its active form, Tenofovir, in the body. Tenofovir inhibits the reverse transcriptase enzyme, preventing viral replication in both HIV and HBV. Lamivudine works similarly, also blocking reverse transcriptase. Together, these medications suppress viral replication, reduce the viral load, and help preserve liver function in HBV patients while improving immune function in HIV patients.
Dosage and Administration:- Recommended Dose: One Tenolam tablet (containing 300 mg Tenofovir and 150 mg Lamivudine) is taken once daily.
- Administration: The tablet should be swallowed whole with a glass of water. It can be taken with or without food. To maximize the medication's effectiveness, take it at the same time each day.
-
Common Side Effects:
- Nausea
- Fatigue
- Headache
- Diarrhea
- Dizziness
-
Serious Side Effects:
- Kidney toxicity (renal issues)
- Lactic acidosis (buildup of lactic acid in the body)
- Hepatomegaly (liver enlargement) and steatosis (fatty liver)
- Bone mineral density loss (osteomalacia)
Regular kidney and liver function tests are recommended during treatment.
Precautions:- Kidney Impairment: Use caution in patients with pre-existing kidney conditions. Renal function should be monitored during treatment.
- Liver Disease: Regular liver function monitoring is essential, especially for patients with chronic hepatitis B or other liver conditions.
- Pregnancy: Category C: There may be risks to the fetus, so consult your healthcare provider if pregnant or planning to become pregnant.
- Breastfeeding: Both Tenofovir and Lamivudine are excreted in breast milk. Consult your doctor before breastfeeding.
- Store Tenolam Tablets at room temperature (15°C to 30°C), away from light and moisture.
- Keep out of reach of children and store in the original packaging.
Tenolam Tenofovir Disoproxil Fumarate and Lamivudine Tablets offer a combination therapy for the treatment of HIV-1 infection and chronic hepatitis B. This dual-drug formulation helps manage viral replication, improve immune function in HIV, and protect liver health in HBV patients. Regular follow-up care, including monitoring of kidney and liver function, is crucial for safe and effective use.
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Sofocure 400 mg Tablets
Product Price: Rs 3,200 / BottleGet Best Price
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Product Details:
| Strength | 400 mg |
| Packaging Size | 28 Tablet |
| Composition | Sofosbuvir 400 mg |
| Treatment | Chronic Hepatitis C Virus (HCV) Infecti |
| Brand | Sofocure 400 mg |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Dose/Strength | 400 mg |
Sofocure 400 mg Tablets
Overview:Sofocure 400 mg Tablets contain Sofosbuvir, an antiviral medication used in the treatment of chronic hepatitis C (HCV) infection. Sofosbuvir is classified as a direct-acting antiviral (DAA) and is a nucleotide analog inhibitor that targets the NS5B RNA polymerase enzyme, which is essential for the replication of the hepatitis C virus. By inhibiting this enzyme, Sofosbuvir prevents the virus from replicating, reducing the viral load, and helping to achieve a sustained virologic response (SVR). SVR is a marker of viral clearance, which can result in the cure of the infection.
Indications:Sofocure 400 mg Tablets are primarily indicated for the treatment of:
- Chronic Hepatitis C (HCV) infection: Used in combination with other antiviral agents (e.g., Daclatasvir, Ledipasvir, or Ribavirin) based on the genotype of the virus and the patient's clinical condition. It is effective in treating genotypes 1, 2, 3, and 4 of HCV.
Sofosbuvir works by inhibiting the NS5B RNA polymerase enzyme that is responsible for replicating the hepatitis C virus. By preventing the replication of the viral genome, Sofosbuvir reduces the overall viral load in the bloodstream. This action helps improve liver function and, in many cases, can lead to the complete eradication of the virus, offering a potential cure for the patient.
Dosage and Administration:- Recommended Dose: The standard dose for Sofocure 400 mg is one tablet daily.
- Administration: Sofosbuvir should be taken orally with or without food. The tablet should be swallowed whole, and it should not be crushed or chewed. It is important to take Sofocure at the same time every day for consistent therapeutic effects.
- Common Side Effects: Fatigue, headache, nausea, insomnia, and anemia (when combined with Ribavirin).
- Serious Side Effects: Hepatitis B reactivation in co-infected patients, liver damage in advanced cirrhosis, and drug interactions with other antiviral agents. Regular liver and kidney function monitoring is recommended.
- Kidney Impairment: Caution is advised for those with severe renal impairment or end-stage renal disease (ESRD).
- Pregnancy: Sofosbuvir is often used with Ribavirin, which is contraindicated during pregnancy due to teratogenic risks. Women of childbearing age should use effective contraception.
- Breastfeeding: Consult a healthcare provider before breastfeeding during treatment.
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Sofocure 400 mg Tablets are an effective treatment for chronic hepatitis C infection. When combined with other antiviral medications, Sofosbuvir helps clear the virus from the body and improve liver health. Regular medical monitoring is essential to ensure safe and effective treatment.
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Tafnat Tenofovir Alafenamide 25 mg Tablets
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Dose Strength | 25 mg |
| Composition | Tenofovir Alafenamide 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Brand Name | Tfnat 25 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Chronic hepatitis B |
Tafnat Tenofovir Alafenamide 25 mg Tablets
Overview:Tafnat 25 mg Tablets contain Tenofovir Alafenamide (TAF), a nucleotide reverse transcriptase inhibitor (NRTI) used to treat HIV-1 infection and chronic hepatitis B (HBV). TAF is a prodrug of Tenofovir, which is selectively activated in the body to deliver the active metabolite, Tenofovir, directly to the cells where it inhibits the reverse transcriptase enzyme. This enzyme is essential for the replication of both HIV and HBV. By blocking this enzyme, TAF helps reduce viral replication, lower viral load, and improve immune function in HIV patients, while also controlling HBV replication.
Indications:Tafnat 25 mg Tablets are indicated for:
- HIV-1 Infection: In combination with other antiretroviral agents as part of a combination antiretroviral therapy (ART) regimen in adults and children.
- Chronic Hepatitis B (HBV): For the treatment of chronic HBV infection in adults with evidence of active viral replication and liver damage.
Tenofovir Alafenamide (TAF) is a prodrug of Tenofovir, meaning it is converted to its active form, Tenofovir, after entering cells. Tenofovir inhibits the reverse transcriptase enzyme, which HIV and HBV use to replicate their genetic material. By blocking reverse transcriptase, TAF reduces viral replication, lowers the viral load, and improves immune function in HIV patients, while preventing further liver damage in HBV patients.
Dosage and Administration:- Recommended Dose: One Tafnat 25 mg tablet is taken once daily, usually in combination with other HIV or HBV medications.
- Administration: Take the tablet with or without food. Swallow the tablet whole with a glass of water. It is important to take the medication at the same time each day for the best effect.
- Common Side Effects: Nausea, headache, fatigue, and diarrhea.
- Serious Side Effects: Kidney toxicity, liver problems (e.g., lactic acidosis, hepatomegaly), and bone mineral density loss (osteomalacia). Monitoring kidney and liver function is advised during treatment.
- Kidney Impairment: Use with caution in patients with pre-existing kidney disease. Regular monitoring of renal function is recommended.
- Liver Disease: In patients with HBV, liver function should be monitored regularly, especially after discontinuing treatment.
- Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.
Store Tafnat 25 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Tafnat Tenofovir Alafenamide 25 mg Tablets are an effective treatment for HIV-1 infection and chronic hepatitis B. When taken as prescribed, it helps reduce viral load, improves immune function, and prevents liver damage in HBV patients. Regular medical follow-ups are necessary to monitor potential side effects, particularly kidney and liver function.
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Ricovir Tenofovir 300 mg Tablets
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg |
| Composition | Tenofovir Disoproxil Fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Brand Name | Ricovir 300 mg |
| Manufacturers | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Ricovir Tenofovir 300 mg Tablets
Overview:
Ricovir Tenofovir 300 mg Tablets contain Tenofovir Disoproxil Fumarate, a nucleotide reverse transcriptase inhibitor (NRTI), used to treat HIV-1 infection and chronic hepatitis B virus (HBV) infection. Tenofovir works by inhibiting the action of reverse transcriptase, an enzyme necessary for the replication of the HIV and HBV viruses. By stopping the virus from replicating, Ricovir helps reduce the viral load in the body, preventing further damage to the immune system.
Indications:
Ricovir is indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen for adults and children over 2 years old.
- Chronic Hepatitis B: In adults with compensated liver disease.
Mechanism of Action:
- Tenofovir: Inhibits the reverse transcriptase enzyme in the HIV or HBV virus, preventing viral replication. It is converted into the active metabolite tenofovir diphosphate inside cells, which directly interferes with viral RNA and DNA synthesis.
Dosage and Administration:
- Recommended Dose: One tablet (300 mg) taken orally once a day with or without food.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it’s almost time for the next dose. Do not double the dose.
Side Effects:
Common side effects of Ricovir may include:
- Diarrhea, headache, dizziness, and nausea.
- Serious side effects may include:
- Renal dysfunction: Kidney problems may occur, especially in patients with pre-existing kidney disease.
- Liver issues: Hepatitis or worsening of HBV infection if treatment is stopped suddenly.
- Bone mineral density loss: Long-term use may lead to bone thinning and fractures.
Precautions:
- Renal Impairment: Regular monitoring of kidney function is essential.
- Hepatic Impairment: Caution is required in patients with liver disease, especially hepatitis B.
- Pregnancy and Breastfeeding: Consult your healthcare provider. Ricovir is not recommended during pregnancy unless absolutely necessary.
Monitoring:
- Kidney Function: Serum creatinine and eGFR should be monitored regularly.
- Liver Function: Liver enzymes (ALT, AST) should be tested before and during treatment.
Storage:
Store Ricovir Tenofovir tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of the reach of children.
Conclusion:
Ricovir Tenofovir 300 mg Tablets are a key part of combination therapy for managing HIV-1 and chronic hepatitis B, reducing viral load and improving immune function. Regular monitoring for side effects, particularly kidney and liver function, is essential to ensure safe and effective treatment.
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Tenohep 300 Mg Tablet
Product Price: Rs 150 / BoxGet Best Price
Product Brochure
Product Details:
| Dose/Strength | 300 mg |
| Composition | Tenofovir Disoproxil Fumarate |
| Packaging Size | 1x10Tablets |
| Brand Name | Tenohep 300 mg |
| Manufacturers | Zydus Cadila |
| Treatment | HIV infections, Chronic hepatitis. |
Tenohep 300 mg Tablet
Overview: Tenohep (Tenofovir Disoproxil Fumarate 300 mg Tablet) is an antiretroviral medication used to treat chronic hepatitis B and HIV infection. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HIV and hepatitis B viruses. By blocking this enzyme, Tenohep helps to prevent the virus from multiplying, improving liver function and reducing viral load.
Indications: Tenohep 300 mg Tablet is primarily indicated for:
- Chronic Hepatitis B (HBV): To treat chronic hepatitis B infection in adults.
- HIV-1 Infection: Used in combination with other antiretroviral agents for the treatment of HIV-1 infection.
Mechanism of Action: The active ingredient, Tenofovir Disoproxil Fumarate, is converted into Tenofovir inside the body. Tenofovir works by:
- Inhibiting reverse transcriptase, an enzyme that the hepatitis B virus and HIV need to replicate their genetic material.
- Reducing the viral load in the bloodstream, which can help improve liver function in hepatitis B patients and reduce the progression of HIV.
Dosage and Administration:
- Recommended Dose: 1 tablet (300 mg) once daily for adults, with or without food.
- Administration: Swallow the tablet whole with a full glass of water. It is recommended to take it at the same time each day.
Side Effects:
- Common Side Effects: Nausea, headache, fatigue, and diarrhea.
- Serious Side Effects: Kidney problems, liver issues, bone loss, lactic acidosis (a rare but serious condition), and pancreatitis.
Precautions:
- Renal Impairment: Regular kidney function tests are recommended during treatment.
- Pregnancy: Consult a doctor before using during pregnancy.
- Bone Health: Regular bone density monitoring may be necessary.
Storage: Store Tenohep 300 mg Tablet at room temperature (15°C to 30°C) in a dry place, away from light and moisture.
Conclusion: Tenohep 300 mg Tablet is a valuable medication in managing chronic hepatitis B and HIV infection. It helps control viral replication and improve quality of life. Monitoring kidney function and bone health is essential during treatment.
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Tenvir Tenofovir 300 mg Tablets
Product Price: Rs 1,200 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg |
| Composition | Tenofovir Disoproxil 300 mg |
| Packaging Size | 1x30Tablets |
| Brand Name | Tenvir 300 mg |
| Manufactured | Cipla Ltd |
| Treatment | HIV, Chronic hepatitis B. |
Tenvir Tenofovir 300mg Tablets
Overview: Tenvir is a medication that contains Tenofovir Disoproxil Fumarate (300 mg), an antiretroviral drug used to treat HIV-1 infection and chronic hepatitis B (HBV). Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is necessary for the HIV virus to replicate. By blocking this enzyme, Tenvir helps reduce the viral load and improves immune function in patients with HIV or HBV.
Indications: Tenvir 300 mg Tablet is indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen in adults and children.
- Chronic Hepatitis B (HBV): For adults with HBV infection who have evidence of active viral replication and liver damage.
Mechanism of Action: Tenofovir works by inhibiting reverse transcriptase, an enzyme used by HIV and HBV to replicate their genetic material. By blocking this enzyme, Tenofovir prevents the virus from multiplying, reducing viral load, and slowing the progression of HIV or HBV infection.
Dosage and Administration:
- Recommended Dose: One Tenvir 300 mg tablet once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It is important to take Tenvir regularly at the same time each day to maximize its effectiveness.
Side Effects:
- Common Side Effects: Headache, fatigue, nausea, diarrhea, and dizziness.
- Serious Side Effects: Lactic acidosis, liver problems, kidney toxicity, and bone mineral density loss. Regular monitoring of kidney function and liver enzymes is recommended.
Precautions:
- Kidney Impairment: Use with caution in patients with pre-existing kidney disease.
- Liver Disease: Regular monitoring is required for patients with hepatitis or liver problems.
- Pregnancy: Consult a healthcare provider if pregnant or planning to become pregnant.
Storage: Store Tenvir 300 mg tablets at room temperature (15°C to 30°C), away from light and moisture.
Conclusion: Tenvir Tenofovir 300 mg Tablet is an effective treatment for HIV and chronic hepatitis B. It should be taken as prescribed to ensure optimal viral suppression and reduce the risk of resistance. Regular medical check-ups are necessary for monitoring side effects.
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Tenofovir Disoproxil Fumarate Tablets (Teravir 300 mg Tablet)
Product Price: Rs 700 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg |
| Composition | Tenofovir disoproxil fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Brand Name | Teravir 300 mg Table |
| Manufacturers | Cipla Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Tenofovir Disoproxil Fumarate Tablets (Teravir)
Overview: Tenofovir Disoproxil Fumarate (Teravir) is an antiretroviral medication used for the treatment of HIV-1 infection and chronic hepatitis B. It is classified as a nucleoside reverse transcriptase inhibitor (NRTI). Teravir works by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of HIV and hepatitis B virus. By blocking this enzyme, it reduces viral replication, helping to control the spread of the virus in the body. Teravir is commonly used in combination with other antiretroviral agents.
Indications:
- HIV-1 infection: Teravir is used as part of a combination therapy for HIV in adults and children over 35 kg.
- Chronic Hepatitis B: Teravir is used for the treatment of chronic hepatitis B in adults with evidence of active viral replication.
Mechanism of Action: Tenofovir Disoproxil Fumarate is metabolized into the active compound Tenofovir in the body. As an NRTI, it inhibits reverse transcriptase, preventing viral RNA from being converted into DNA. This stops the replication of HIV and hepatitis B viruses, reducing the viral load and improving clinical outcomes.
Dosage and Administration:
- Recommended Dose: 300 mg once daily.
- Administration: Take one tablet daily, with or without food. Do not chew or crush the tablet.
- Renal Adjustment: Use with caution in patients with renal impairment; dosage adjustments may be needed.
Side Effects:
- Common Side Effects: Nausea, fatigue, headache, diarrhea, and dizziness.
- Serious Side Effects: Renal toxicity, lactic acidosis, liver damage, and decreased bone mineral density.
Precautions:
- Renal Impairment: Monitor renal function regularly.
- Liver Disease: Monitor liver enzymes in patients with chronic hepatitis B or liver cirrhosis.
- Pregnancy: Use Teravir only if necessary during pregnancy, as it is secreted in breast milk.
Storage: Store Teravir at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion: Teravir (Tenofovir Disoproxil Fumarate) is an essential treatment for managing HIV and hepatitis B. Adherence to the prescribed regimen and regular monitoring for side effects ensure optimal therapeutic outcomes.
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Tenofovir Disoproxil Fumarate Tablets (Tenof 300 mg Tablet)
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg |
| Composition | Tenofovir Disoproxil Fumarate 300 mg |
| Packaging Size | 1x30Tablets |
| Brand Name | Tenofovir Disoproxil Fumarate 300 mg |
| Manufacturers | Hetero Drugs Ltd |
| Treatment | HIV infections, Chronic hepatitis. |
Tenofovir Disoproxil Fumarate Tablets (Tenof)
Overview:Tenofovir Disoproxil Fumarate (brand name Tenof) is an antiviral medication primarily used to treat HIV-1 infection and chronic hepatitis B (HBV). It belongs to the class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). Tenofovir works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of both HIV and HBV. By blocking this enzyme, Tenof reduces viral replication, lowers viral load, and helps protect the immune system in HIV patients, while also improving liver function in those with HBV.
Indications:Tenofovir Disoproxil Fumarate (Tenof) is indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen for adults and children.
- Chronic Hepatitis B (HBV): For adults with chronic HBV infection showing active viral replication and evidence of liver damage.
Tenofovir is converted to its active form, Tenofovir, once in the body. Tenofovir inhibits reverse transcriptase, an enzyme HIV and HBV use to replicate their viral genomes. By blocking this enzyme, Tenof prevents the viruses from multiplying, reducing viral load, and helping to improve immune function in HIV patients and liver health in those with HBV.
Dosage and Administration:- Recommended Dose: One 300 mg tablet of Tenofovir Disoproxil Fumarate is typically taken once daily.
- Administration: The tablet can be taken with or without food. It should be swallowed whole with a glass of water. It is important to take Tenof at the same time each day for consistent drug levels in the body.
-
Common Side Effects:
- Nausea
- Fatigue
- Headache
- Diarrhea
- Dizziness
-
Serious Side Effects:
- Kidney toxicity (renal issues)
- Lactic acidosis (a rare but serious condition involving buildup of lactic acid)
- Hepatomegaly (enlarged liver) and steatosis (fatty liver)
- Bone mineral density loss (osteomalacia)
Regular monitoring of kidney and liver function is recommended during treatment.
Precautions:- Kidney Impairment: Tenof should be used cautiously in patients with pre-existing kidney disease. Kidney function should be regularly monitored (e.g., serum creatinine, eGFR).
- Liver Disease: In patients with chronic HBV or other liver issues, liver function should be monitored closely.
- Pregnancy: Category B: No known harm in animal studies, but always consult your doctor if you are pregnant or planning to become pregnant.
- Breastfeeding: Tenofovir is excreted in breast milk. Discuss with your healthcare provider whether breastfeeding is advisable.
- Store Tenof tablets at room temperature (15°C to 30°C), away from moisture and light.
- Keep out of reach of children and store in the original packaging.
Tenofovir Disoproxil Fumarate (Tenof) is an effective treatment for HIV and chronic hepatitis B. It reduces viral load, improves immune function, and helps prevent the progression of liver disease in HBV patients. Adherence to the prescribed dosage and regular monitoring of kidney and liver function are crucial for ensuring the best outcomes during treatment.
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Hepbest Tenofovir Alafenamide 25 mg Tablets
Product Price: Rs 1,000 / BottleGet Best Price
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Product Details:
| Dose Strength | 25 mg |
| Composition | Tenofovir Alafenamide 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Brand Name | Hepbest 25 mg |
| Manufacturer | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | Chronic Hepatitis B |
Hepbest Tenofovir Alafenamide 25mg Tablets
Overview: Hepbest (Tenofovir Alafenamide) is an antiviral medication used in the treatment of chronic hepatitis B (HBV) infection in adults and pediatric patients over 12 years old. It is a nucleotide reverse transcriptase inhibitor (NRTI) that works by inhibiting the HBV virus’s reverse transcriptase enzyme, thus preventing the replication of the virus in the liver. By blocking the virus’s ability to reproduce, Hepbest reduces viral load, improves liver function, and reduces the risk of liver damage.
Indications: Hepbest 25mg Tablets are indicated for:
- Chronic Hepatitis B (HBV): Treatment of chronic HBV infection in adults and pediatric patients (aged 12 and older), to reduce viral load and prevent liver damage.
- Prevention of Liver Damage: It is used to prevent complications like cirrhosis, liver failure, and liver cancer in patients with chronic HBV.
Mechanism of Action: Tenofovir Alafenamide is a prodrug of Tenofovir, which gets converted into the active form in the bloodstream. It works by inhibiting the reverse transcriptase enzyme in the hepatitis B virus, which is essential for viral replication. This prevents the virus from multiplying and reduces its presence in the liver.
Dosage and Administration:
- Recommended Dose: The usual dose is 25 mg once daily.
- Administration: Take Hepbest tablets orally with or without food.
- Missed Dose: If a dose is missed, it should be taken as soon as possible, unless it is close to the time for the next dose.
Side Effects:
- Common side effects: Headache, fatigue, and nausea.
- Serious side effects: Kidney problems, bone density loss, and lactic acidosis (rare but serious).
Precautions:
- Kidney function: Monitor kidney function during treatment.
- Bone health: Periodic monitoring of bone density is advised, especially for long-term use.
- Pregnancy and breastfeeding: Hepbest should be used with caution in pregnant or breastfeeding women.
Storage: Store Hepbest 25mg Tablets at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion: Hepbest (Tenofovir Alafenamide 25mg) is a safe and effective treatment for chronic hepatitis B infection, offering improved safety profiles over older tenofovir formulations. Regular monitoring for kidney and bone health is essential during long-term use.
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Velpanat Sofosbuvir 400 mg Velpatasvir 100 mg
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Strength | 400 mg+ 100 mg |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Brand | Velpanat 400 mg |
| Manufacturer | Natco Pharma Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Velpanat (Sofosbuvir 400 mg + Velpatasvir 100 mg)
Overview:
Velpanat is a combination tablet containing Sofosbuvir (400 mg) and Velpatasvir (100 mg). This medication is used to treat chronic hepatitis C (HCV) infection. Sofosbuvir is an NS5B polymerase inhibitor, while Velpatasvir is an NS5A inhibitor. Together, they work to inhibit the replication of the hepatitis C virus, effectively lowering the viral load and improving liver function in infected individuals.
Indications:
Velpanat is indicated for the treatment of chronic hepatitis C infection in adult patients with genotype 1, 2, 3, 4, 5, or 6 of HCV. It is used in both treatment-naive and treatment-experienced patients, and those with or without cirrhosis.
Mechanism of Action:
- Sofosbuvir: Inhibits the NS5B RNA-dependent RNA polymerase, preventing viral RNA replication.
- Velpatasvir: Inhibits the NS5A protein, which is essential for viral replication and assembly.
By inhibiting both the NS5B polymerase and NS5A proteins, Velpanat blocks critical steps in the HCV lifecycle, preventing the virus from multiplying and spreading.
Dosage and Administration:
- Recommended Dose: One tablet of Velpanat (Sofosbuvir 400 mg / Velpatasvir 100 mg) is taken once daily with or without food.
- Treatment Duration: Typically 12 weeks; however, treatment may vary based on the patient's HCV genotype, prior treatments, and liver condition.
Side Effects:
- Common: Fatigue, headache, nausea, and anemia.
- Serious: Risk of hepatitis B reactivation in co-infected patients, liver issues, and allergic reactions.
Precautions:
- Hepatitis B: Before starting treatment, test for hepatitis B virus (HBV) infection, as HBV can reactivate during HCV treatment.
- Renal Impairment: Caution in patients with severe kidney impairment.
Storage:
Store Velpanat at room temperature (15°C to 30°C), away from light and moisture. Keep out of the reach of children.
Conclusion:
Velpanat is a highly effective and convenient treatment for HCV, combining two antiviral agents that target different steps in the viral replication process. It provides a safe and effective option for patients with chronic hepatitis C.
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Tenvir L Tablets
Product Price: Rs 1,250 / BoxGet Best Price
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Product Details:
| Strength | 25 mg |
| Packaging Type | Box |
| Brand | Tenvir L |
| Manufacured By | Cipla |
| Pack Size | 30 Tablet |
Tenvir L Tablets
Overview:
Tenvir L Tablets contain two active ingredients: Lamivudine (150mg) and Tenofovir Disoproxil Fumarate (300mg). These are used for the treatment of HIV/AIDS and chronic hepatitis B (HBV). Lamivudine and Tenofovir are both nucleoside reverse transcriptase inhibitors (NRTIs) that work by inhibiting the replication of HIV and HBV, helping to control viral load and slow disease progression.
Indications:
- HIV/AIDS: Tenvir L is used as part of combination antiretroviral therapy (ART) in HIV-infected adults and children aged 2 years and older.
- Chronic Hepatitis B: It is also indicated for the treatment of HBV in adults with evidence of active viral replication.
Mechanism of Action:
- Lamivudine and Tenofovir are converted into their active forms (lamivudine triphosphate and tenofovir diphosphate) inside the infected cells. These active forms inhibit the reverse transcriptase enzyme, stopping the conversion of viral RNA into DNA. This halts viral replication in HIV and HBV.
Dosage and Administration:
- HIV Treatment: One tablet (150mg Lamivudine/300mg Tenofovir) once daily, typically in combination with other antiretroviral drugs.
- HBV Treatment: One tablet once daily, as directed by your healthcare provider.
- Administration: Swallow the tablet whole with or without food. Take at the same time each day.
- Missed Dose: If you miss a dose, take it as soon as you remember, unless it's close to the next dose.
Side Effects:
- Common: Fatigue, headache, nausea, diarrhea, dizziness.
- Serious: Lactic acidosis, liver problems, kidney damage, bone loss, pancreatitis.
Precautions:
- Renal Impairment: Monitor kidney function, especially in those with pre-existing kidney disease.
- Liver Impairment: Regular monitoring of liver function is recommended.
- Pregnancy: Consult a healthcare provider before use during pregnancy.
Storage:
Store at room temperature (15°C to 30°C), away from heat and moisture. Keep out of reach of children.
Conclusion:
Tenvir L Tablets are an effective treatment for managing HIV and HBV, improving quality of life, and slowing the progression of these viral infections when used as part of a comprehensive treatment regimen.
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Tenvir EM Tablet
Product Price: Rs 1,500 / BoxGet Best Price
Minimum Order Quantity: 100 Box
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Product Details:
| Strength | 25 mg |
| Packaging Type | Box |
| Brand | Tenvir EM |
| Manufacured By | Cipla |
| Pack Size | 30 Tablets |
Tenvir EM Tablet (Tenofovir Disoproxil Fumarate / Emtricitabine)
Overview:
Tenvir EM is a combination tablet containing Tenofovir Disoproxil Fumarate (TDF) 300 mg and Emtricitabine (FTC) 200 mg, both of which are antiretroviral medications. This medication is primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children. Tenvir EM is also used in pre-exposure prophylaxis (PrEP) to reduce the risk of HIV infection in high-risk individuals. By inhibiting the reverse transcriptase enzyme, it helps to prevent the replication of the virus in the body.
Indications:
- HIV Infection: Tenvir EM is used as part of a combination antiretroviral therapy (ART) regimen for the treatment of HIV-1 infection.
- Pre-exposure Prophylaxis (PrEP): It is used to reduce the risk of HIV infection in individuals at high risk of contracting the virus.
Mechanism of Action:
- Tenofovir Disoproxil Fumarate (TDF): A nucleotide reverse transcriptase inhibitor (NRTI) that blocks the activity of reverse transcriptase, an enzyme the HIV virus needs to replicate.
- Emtricitabine (FTC): A nucleoside reverse transcriptase inhibitor (NRTI) that also inhibits reverse transcriptase to stop the replication of HIV.
By inhibiting this enzyme, both drugs prevent the virus from multiplying, reducing viral load in the blood and increasing the CD4+ cell count.
Dosage and Administration:
- Recommended dose: The usual dose for adults and adolescents is one Tenvir EM tablet (300 mg TDF + 200 mg FTC) once daily with or without food.
- Renal Impairment: Dose adjustments may be required in patients with renal dysfunction.
- Missed dose: If a dose is missed, it should be taken as soon as remembered, unless it is near the time for the next dose. Do not take two doses at the same time.
Side Effects:
Common side effects include:
- Nausea
- Diarrhea
- Fatigue
- Headache
- Insomnia
Serious side effects include:
- Kidney problems: Tenvir EM can affect kidney function, so kidney function tests are important during treatment.
- Bone density loss: Prolonged use can affect bone mineral density, leading to a higher risk of fractures.
- Lactic acidosis: A rare but serious side effect that involves a buildup of lactic acid in the blood.
- Hepatotoxicity: Liver toxicity, particularly in patients with preexisting liver conditions.
Precautions:
- Renal function: Monitoring of renal function is required before and during treatment.
- Liver disease: Patients with a history of liver disease, including hepatitis B or C, should be closely monitored.
- Pregnancy: Tenvir EM is classified as Pregnancy Category B and should be used during pregnancy only if clearly needed.
Monitoring:
- Renal function: Kidney function should be regularly monitored with tests for creatinine clearance.
- Liver function: Liver enzymes and hepatitis B or C status should be regularly checked during treatment.
Storage:
Store Tenvir EM tablets at room temperature (15°C to 30°C) in a dry place, away from light. Keep out of reach of children.
Conclusion:
Tenvir EM is a highly effective combination therapy for managing HIV infection and reducing the risk of HIV transmission in high-risk individuals. Regular monitoring for side effects such as kidney dysfunction and bone health is essential for ensuring treatment safety.
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Hepcvel Sofosbuvir And Velpatasvir Tablet
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Strength | 400 mg+ 100 mg |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Brand | Hepcvel 400 mg/100 mg Tablet |
| Manufacturer | Cipla Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Hepcvel (Sofosbuvir and Velpatasvir) Tablet
Overview:
Hepcvel is a combination tablet containing Sofosbuvir (400 mg) and Velpatasvir (100 mg), used for the treatment of chronic hepatitis C virus (HCV) infection in adults. This combination therapy targets different stages of the HCV lifecycle, helping to reduce viral replication and improve liver function. Sofosbuvir is a nucleotide analog that inhibits the NS5B polymerase, while Velpatasvir inhibits the NS5A protein, which is crucial for the virus's replication and assembly. Hepcvel is effective across all major HCV genotypes (1-6).
Indications:
Hepcvel is indicated for the treatment of chronic hepatitis C in adults with genotypes 1, 2, 3, 4, 5, or 6. It is used both for treatment-naive patients and those who have previously been treated for HCV. Hepcvel can be prescribed as a monotherapy or in combination with ribavirin for certain patients, especially in more advanced stages of the disease.
Mechanism of Action:
- Sofosbuvir inhibits the NS5B polymerase, an enzyme required for HCV replication.
- Velpatasvir targets and inhibits the NS5A protein, which plays a role in viral replication and assembly.
By targeting two different parts of the virus, Hepcvel effectively suppresses HCV replication, reducing the viral load and promoting a sustained virologic response (SVR).
Dosage and Administration:
- Recommended Dose: The usual dose of Hepcvel is one tablet (400 mg Sofosbuvir / 100 mg Velpatasvir) taken once daily, with or without food.
- Administration: The tablet should be swallowed whole with a glass of water. Do not chew or crush the tablet.
- Missed Dose: If a dose is missed, take it as soon as possible, unless it's almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects may include:
- Fatigue, headache, nausea, insomnia, and diarrhea.
Serious side effects include: - Liver issues, severe allergic reactions, and bradycardia when combined with amiodarone.
Precautions:
- Renal Impairment: Hepcvel is generally safe in patients with mild to moderate renal impairment, but caution is advised for those with severe kidney disease.
- Pregnancy: Sofosbuvir should not be used during pregnancy unless combined with ribavirin, which is contraindicated due to teratogenic effects.
- Drug Interactions: Hepcvel may interact with other drugs, such as HIV medications, anticonvulsants, and certain heart medications. Inform your doctor of all medications you're currently taking.
Monitoring:
Regular monitoring of liver function, HCV RNA levels, and kidney function is recommended during treatment. Periodic monitoring of cardiac function may be necessary when taking Hepcvel with amiodarone.
Storage:
Store Hepcvel at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Hepcvel is a highly effective treatment for chronic hepatitis C. By combining two potent antiviral agents, Sofosbuvir and Velpatasvir, it targets key stages of HCV replication and reduces the viral load. Hepcvel is generally well-tolerated, and regular monitoring helps ensure treatment safety and effectiveness.
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Eltrombopag Olamine Tablets 25 mg (Trombopag 50mg)
Product Price: Rs 1,250 / BoxGet Best Price
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Product Details:
| Packaging size | 7 Tablets in 1 Strip |
| Manufacturer | Natco Pharma Ltd |
| Composition | Eltrombopag 50 mg |
| Brand | Trombopag 50 mg |
| Treatment | Low Platelet Count And Severe Aplastic Anaemia (SAA) |
| Strength | 25 mg |
Eltrombopag Olamine Tablets 50 mg
Overview:Eltrombopag Olamine 25 mg Tablets contain Eltrombopag, a thrombopoietin receptor agonist used to treat thrombocytopenia (low platelet count). It stimulates the production of platelets in the bone marrow. Eltrombopag is indicated for the treatment of chronic immune thrombocytopenia (ITP), severe aplastic anemia, and hepatitis C-related thrombocytopenia (low platelet count due to hepatitis C). By activating the thrombopoietin receptor (c-Mpl) on megakaryocytes and hematopoietic stem cells, Eltrombopag promotes platelet production and increases platelet count.
Indications:- Chronic Immune Thrombocytopenia (ITP): For adults and children (≥1 year) with chronic ITP who have not responded to prior treatments (e.g., corticosteroids, immunoglobulins, or splenectomy).
- Severe Aplastic Anemia: Used in combination with standard immunosuppressive therapy for severe aplastic anemia.
- Hepatitis C-Related Thrombocytopenia: In patients with chronic hepatitis C to increase platelet counts, enabling the use of antiviral therapy.
Eltrombopag binds to and activates the thrombopoietin receptor (c-Mpl) on bone marrow cells, specifically megakaryocytes. This stimulates the production and release of platelets, leading to an increase in platelet counts in the bloodstream.
Dosage and Administration:- Adult dose for ITP: 50 mg once daily (adjusted based on platelet count).
- Pediatric dose: Typically ranges from 25 mg to 50 mg daily, based on weight and age. Eltrombopag should be taken on an empty stomach, at least 2 hours after food or 1 hour before food. It should be swallowed whole with water.
- Common: Fatigue, headache, nausea, diarrhea, and insomnia.
- Serious: Hepatotoxicity (liver dysfunction), thrombotic events (e.g., DVT, PE), and bone marrow disorders (e.g., myelodysplastic syndromes or leukemia). Liver function and platelet counts should be monitored regularly.
- Liver disease: Monitor liver function (ALT, AST) during treatment.
- Pregnancy: Category C – Use only if benefits outweigh risks. Avoid breastfeeding.
- Drug interactions: Inform your healthcare provider about other medications, especially those affecting liver enzymes.
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Eltrombopag Olamine 50 mg Tablets are an effective treatment for thrombocytopenia associated with ITP, severe aplastic anemia, and hepatitis C. Regular monitoring of platelet counts, liver function, and complete blood counts is essential for safe and effective use.
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1100mg Teevir Tablet
Product Price: Rs 950 / BottleGet Best Price
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Product Details:
| Packaging Size | 200 mg/300 mg/600 mg |
| Strength | 200 mg/300 mg/600 mg |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Emtricitabine (200 mg) + Tenofovir disoproxil fumarate (300 mg) + Efavirenz (600 mg) |
| Brand Name | Teevir 200 mg/300 mg/600 mg Tablet |
| Manufacturers | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | HIV infection |
Teevir 1100mg Tablet
Overview:Teevir 1100mg Tablet contains Tenofovir Disoproxil Fumarate (1100 mg), an antiviral drug used primarily for the treatment of chronic hepatitis B (HBV) and HIV-1 infection. Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, essential for both HIV and HBV to replicate their genetic material. By blocking this enzyme, Teevir reduces viral load, improves liver function in HBV, and helps manage HIV in combination with other antiretroviral agents.
Indications:Teevir 1100mg Tablet is indicated for:
- HIV-1 Infection: In combination with other antiretrovirals as part of an antiretroviral therapy (ART) regimen for both adults and children.
- Chronic Hepatitis B (HBV): For adults with chronic HBV infection showing active viral replication and liver damage.
Teevir (Tenofovir Disoproxil Fumarate) is converted to the active form Tenofovir in the body. Tenofovir inhibits reverse transcriptase, a crucial enzyme for the replication of HIV and HBV. By preventing the virus from replicating, it reduces viral load, slows disease progression, and enhances immune system response.
Dosage and Administration:- Recommended Dose: 1100 mg once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It’s important to take Teevir at the same time each day for consistent drug levels.
- Common Side Effects: Nausea, fatigue, headache, dizziness, and diarrhea.
- Serious Side Effects: Kidney problems (renal toxicity), lactic acidosis, liver issues (hepatomegaly and steatosis), and bone mineral density loss. Kidney and liver function should be monitored regularly during treatment.
- Kidney Impairment: Caution is needed for those with pre-existing kidney disease. Regular kidney function monitoring is recommended.
- Liver Disease: Patients with HBV or other liver issues should be closely monitored.
- Pregnancy: Category B (no known risk to fetus in animal studies). Consult with a healthcare provider if pregnant or planning to conceive.
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Teevir 1100mg Tablet is an effective treatment for chronic hepatitis B and HIV-1 infection. Regular follow-up care, including liver and kidney function monitoring, is essential to ensure safety and efficacy.
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Trombopag 25mg Tablet
Product Price: Rs 280 / BoxGet Best Price
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Product Details:
| Strength | 25 mg |
| Packaging size | 4*7 Tablets |
| Composition | Eltrombopag Olamine 25 mg |
| Brand | Trombopag 25 mg |
| Manufactured By | Natco 25 mg |
| Treatment | Severe Aplastic Anemia |
Trombopag 25mg Tablet
Overview:
Trombopag 25mg is an oral medication used to treat chronic immune thrombocytopenia (ITP) and severe aplastic anemia (SAA). It is a thrombopoietin receptor agonist that stimulates the production of platelets in the bone marrow. By binding to the thrombopoietin receptor, Trombopag promotes the production of new platelets, helping to prevent bleeding and reduce the need for platelet transfusions in patients with low platelet counts.
Indications:
Trombopag 25mg Tablet is indicated for:
- Chronic Immune Thrombocytopenia (ITP): To increase platelet count in adult patients who have had an insufficient response to other treatments such as corticosteroids or immunoglobulins.
- Severe Aplastic Anemia (SAA): Used in combination with other therapies for patients with SAA who have not responded to immunosuppressive treatment.
Mechanism of Action:
Trombopag is a synthetic thrombopoietin receptor agonist. It binds to and activates the thrombopoietin receptor (MPL) on the surface of hematopoietic progenitor cells in the bone marrow. This stimulation increases the production of platelets and other blood cells, improving platelet counts and reducing the risk of bleeding in conditions like ITP and SAA.
Dosage and Administration:
- Recommended Dose: The usual starting dose is 25mg once daily. For ITP, the dose may be adjusted based on the platelet count and individual response.
- Administration: Trombopag 25mg is taken orally, with or without food. The tablet should be swallowed whole and not chewed or crushed.
- Missed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose.
Side Effects:
Common side effects include:
- Headache, nausea, fatigue, and diarrhea.
Serious side effects may include: - Liver toxicity: Elevated liver enzymes or jaundice.
- Thrombosis: Increased risk of blood clots.
- Bone Marrow Suppression: Can cause low white blood cell counts, leading to infections.
Precautions:
- Liver Function: Regular monitoring of liver enzymes is essential.
- Thrombosis Risk: Caution in patients with a history of blood clots.
- Pregnancy and Breastfeeding: Use only if the benefits outweigh the risks.
Storage:
Store Trombopag 25mg Tablets at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Trombopag 25mg Tablet is an effective treatment for chronic ITP and severe aplastic anemia. Monitoring for liver function and the risk of blood clots is essential during treatment.
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Resof L Ledipasvir 90 Mg Sofosbuvir 400 Mg
Product Price: Rs 4,350 / BottleGet Best Price
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Product Details:
| Dose/Strength | 90 mg/400 mg |
| Pack Size | 28 Tablets in 1 Bottle |
| Salt Composition | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Brand Name | Resof-L 400 mg tablet |
| Manufactured | Dr Reddy's Laboratories Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Resof L (Ledipasvir 90mg / Sofosbuvir 400mg)
Overview:
Resof L is a fixed-dose combination of two antiviral drugs, Ledipasvir (90mg) and Sofosbuvir (400mg). It is used to treat chronic hepatitis C virus (HCV) infection in adults. This combination works by inhibiting specific enzymes essential for the replication of the HCV virus, thus reducing the viral load and preventing further liver damage. Resof L is used for the treatment of HCV genotype 1 infection, and in some cases, in combination with other antiviral agents for other genotypes.
Indications:
Resof L is indicated for:
- Chronic Hepatitis C: For the treatment of adults with HCV genotype 1 infection, with or without cirrhosis.
- Co-infection with HIV: Can be used in patients with both HIV and chronic HCV infection.
- Other Genotypes: In some cases, used in combination with additional antiviral agents to treat other HCV genotypes.
Mechanism of Action:
- Ledipasvir is an NS5A inhibitor that prevents the replication of the HCV virus by binding to the NS5A protein, which is necessary for viral replication and assembly.
- Sofosbuvir is an NS5B polymerase inhibitor that blocks the RNA polymerase enzyme, which is essential for viral RNA synthesis. Together, these drugs work synergistically to inhibit different stages of the HCV life cycle, significantly reducing the viral load and improving liver function.
Dosage and Administration:
- Recommended Dose: The usual dose is one tablet of Resof L once daily, taken with or without food.
- Administration: Swallow the tablet whole; do not crush or chew.
- Missed Dose: If you miss a dose, take it as soon as possible, unless it is close to the next scheduled dose. Do not double the dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, and diarrhea.
Serious side effects may include: - Hepatotoxicity: Liver function should be monitored during treatment.
- Bradycardia: Risk of slow heart rate when used with certain other medications.
- Rash and severe allergic reactions.
Precautions:
- Pregnancy: Not recommended during pregnancy unless clearly needed.
- Drug Interactions: Can interact with other medications, so consult your healthcare provider about all medications you are taking.
- Renal Impairment: Dose adjustments may be required in patients with severe renal impairment.
Storage:
Store Resof L at room temperature (20°C to 25°C), away from light and moisture, and out of the reach of children.
Conclusion:
Resof L (Ledipasvir/Sofosbuvir) is an effective treatment for chronic hepatitis C. It works by inhibiting key viral enzymes, helping to reduce viral load and improve liver health. Regular monitoring for side effects and interactions with other drugs is crucial for safety.
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Ledipasvir Sofosbuvir Tablets (Hepcvir L Tablets)
Product Price: Rs 18,000 / BottleGet Best Price
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Product Details:
| Dose/Strength | 90mg/400mg |
| Packaging Size | 28 Tablets in 1 Bottle |
| Dose | 90 mg/400 mg |
| Composition (salt) | Ledipasvir 90mg + Sofosbuvir 400mg |
| Brand Name | Hepcvir L 90 mg/400 mg Tablet |
| Manufactured | Cipla Ltd |
| Treatment Of | Therapy of Chronic hepatitis C infection (HCV) disease |
Ledipasvir Sofosbuvir Tablets (Hepcvir L Tablets)
Overview:
Hepcvir L Tablets combine two antiviral drugs: Ledipasvir (90 mg) and Sofosbuvir (400 mg). This combination is used for the treatment of chronic hepatitis C virus (HCV) infection in adults. Ledipasvir is an NS5A inhibitor, and Sofosbuvir is an NS5B polymerase inhibitor. Together, they work by inhibiting the replication of the HCV, leading to a reduction in the viral load and improved liver function.
Indications:
- Chronic Hepatitis C (HCV): Hepcvir L is indicated for the treatment of chronic HCV infection in adults with genotype 1, genotype 4, genotype 5, and genotype 6 of the HCV virus. It is used without the need for ribavirin and in combination with other HCV medications in certain cases.
Mechanism of Action:
- Ledipasvir inhibits the NS5A protein, a key component required by the HCV to replicate.
- Sofosbuvir inhibits the NS5B RNA polymerase, preventing the virus from replicating its genetic material.
Together, these medications prevent the virus from replicating and reduce the viral load, aiding in the clearance of the virus from the body.
Dosage and Administration:
- Recommended Dose: One tablet of Hepcvir L (90 mg Ledipasvir/400 mg Sofosbuvir) is taken once daily, with or without food.
- Duration of Treatment: The duration may vary depending on the patient’s genotype and the presence of cirrhosis. Typically, treatment lasts 12 weeks.
- Missed Dose: If you miss a dose, take it as soon as possible, but do not take two doses at once.
Side Effects:
- Common: Fatigue, headache, nausea, diarrhea.
- Serious: Liver problems, reactivation of hepatitis B, allergic reactions, and anemia (if taken with other drugs like ribavirin).
Precautions:
- Hepatitis B Reactivation: Test for HBV before starting treatment, as it can be reactivated during HCV treatment.
- Renal Impairment: Hepcvir L should be used cautiously in patients with severe kidney impairment.
Storage:
Store at room temperature (15°C to 30°C), in a dry place, and protect from light. Keep out of reach of children.
Conclusion:
Hepcvir L Tablets are a highly effective treatment for chronic hepatitis C. The combination of Ledipasvir and Sofosbuvir helps to reduce the viral load and improve liver health, offering a safer and more convenient treatment option for patients with hepatitis C.
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Heptavir 100 mg Tablet
Product Price: Rs 900 / BoxGet Best Price
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Product Details:
| Strength | 100 mg |
| Packaging Size | 10*10 Tablets |
| Brand | Heptavir |
| Manufacturer | Hetro |
| Usage / Application | Hospital |
Heptavir 100 mg Tablet
Overview:
Heptavir (Tenofovir Disoproxil Fumarate) 100 mg Tablet is an antiviral medication used to treat chronic hepatitis B (HBV) and HIV-1 infections. It is a nucleotide reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of both HIV and HBV. By preventing the replication of the virus, Heptavir helps reduce the viral load, improve liver function, and slow the progression of liver damage in patients with chronic hepatitis B. In HIV, it is used as part of combination therapy.
Indications:
Heptavir 100 mg Tablet is indicated for the treatment of:
- Chronic Hepatitis B: For adults with evidence of active HBV replication and liver inflammation.
- HIV-1 Infection: As part of a combination regimen for the treatment of HIV-1 infection in adults and children (older than 12 years).
Mechanism of Action:
Tenofovir, the active ingredient in Heptavir, is a nucleotide analogue that mimics natural building blocks of DNA. Once incorporated into the growing viral DNA chain, it causes premature chain termination, thus preventing the virus from replicating. In HBV, Tenofovir suppresses viral replication by inhibiting reverse transcriptase. In HIV, it reduces the viral load when used in combination with other antiretroviral agents.
Dosage and Administration:
- Chronic Hepatitis B: The typical dose is 100 mg once daily.
- HIV-1 Infection: For adults, the usual dose is 300 mg daily as part of combination therapy. The dose for children (12 years and older) is adjusted based on body weight.
- Administration: Take Heptavir 100 mg Tablet orally with or without food. Swallow the tablet whole; do not chew or crush.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it is almost time for your next dose.
Side Effects:
Common side effects of Heptavir include:
- Headache, nausea, diarrhea, and fatigue.
Serious side effects may include: - Kidney toxicity, liver problems, bone mineral density loss, and lactic acidosis.
Precautions:
- Renal Impairment: Patients with reduced kidney function should use Heptavir with caution. Regular kidney function tests are recommended during treatment.
- Pregnancy and Breastfeeding: Heptavir is classified as Category B for pregnancy. It is recommended for use during pregnancy only if the benefits outweigh the risks. It is not recommended for use while breastfeeding.
- Drug Interactions: Heptavir may interact with other medications that affect kidney or bone health. Always inform your healthcare provider about other medications you are taking.
Monitoring:
Regular monitoring of kidney function, liver enzymes, and bone health is essential during treatment with Heptavir.
Storage:
Store Heptavir 100 mg Tablet at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Heptavir 100 mg Tablet is an effective treatment for chronic hepatitis B and HIV-1 infection when used as part of a combination regimen. Regular monitoring for side effects and patient adherence to prescribed therapy are essential for optimal treatment outcomes.
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Resof Total 400 mg/100 mg Tablet
Product Price: Rs 6,400 / BottleGet Best Price
Product Brochure
Product Details:
| Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Dose/Strength | 400 mg/100 mg |
| Pack Type | 28 Tablets in 1 Bottle |
| Salt Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Brand Name | Resof Total 400 mg/100 mg Tablet |
| Manufactured By | Dr Reddy's Laboratories Ltd |
| Treatment Of | Chronic hepatitis C virus (HCV) infection |
Resof Total 400mg/100mg Tablet
Overview:
Resof Total 400mg/100mg Tablet is a fixed-dose combination medication used in the treatment of chronic hepatitis C. It contains Sofosbuvir (400 mg) and Velpatasvir (100 mg), both direct-acting antiviral (DAA) agents that work by targeting the hepatitis C virus (HCV). Sofosbuvir inhibits the viral RNA polymerase, preventing viral replication, while Velpatasvir inhibits the HCV NS5A protein, which is essential for viral replication and assembly. This combination therapy is highly effective against all HCV genotypes.
Indications:
Resof Total 400mg/100mg Tablet is indicated for:
- Chronic Hepatitis C: Used for the treatment of chronic hepatitis C infection in adults, regardless of HCV genotype. It is often prescribed for patients with or without cirrhosis or in combination with other medications, depending on the individual’s condition.
Mechanism of Action:
Sofosbuvir is a nucleotide analog inhibitor, blocking the NS5B polymerase enzyme, which is necessary for the replication of HCV RNA. Velpatasvir is an NS5A inhibitor, preventing the formation of the viral replication complex. Together, these medications inhibit multiple steps of the HCV lifecycle, leading to a significant reduction in viral load and, eventually, viral eradication.
Dosage and Administration:
- Recommended Dose: The usual dose is one tablet (400mg Sofosbuvir/100mg Velpatasvir) once daily with or without food.
- Administration: The tablet should be swallowed whole with a glass of water.
- Missed Dose: If a dose is missed, take it as soon as possible, unless it is close to the time for the next dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, and diarrhea.
Serious side effects may include: - Hepatitis reactivation in patients co-infected with HBV.
- Severe liver problems, especially in patients with cirrhosis.
- Rash or other allergic reactions.
Precautions:
- Liver Disease: Monitor liver function, especially in patients with pre-existing liver conditions.
- Pregnancy: Use caution during pregnancy, especially if co-administered with ribavirin, which is contraindicated during pregnancy.
- Drug Interactions: May interact with other medications, particularly those affecting liver enzymes (CYP3A).
Storage:
Store Resof Total 400mg/100mg Tablets at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Resof Total 400mg/100mg Tablet offers a convenient, once-daily treatment for chronic hepatitis C, with a high cure rate and a manageable side effect profile. Regular monitoring for liver function and any drug interactions is essential during treatment.
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Ledihep Tablet (Ledipasvir 90 mg + Sofosbuvir 400 mg)
Product Price: Rs 3,350 / BottleGet Best Price
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Product Details:
| Dose/Strength | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Pack Type | 28 Tablet in 1 Bottle |
| Salt Composition | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Brand Name | Ledihep Tablet |
| Manufactured | Zydus Cadila |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
490mg Ledihep Tablet
Overview:
Ledihep (Ledipasvir 490mg) is an antiviral medication used in combination with Sofosbuvir for the treatment of chronic hepatitis C virus (HCV) infection. It is a direct-acting antiviral (DAA) that targets the NS5A protein of the HCV, inhibiting viral replication and assembly. By blocking the NS5A protein, Ledihep prevents the virus from multiplying and spreading, leading to a reduction in viral load and eventual clearance of the infection. It is typically used in combination with other medications, including Sofosbuvir, for a complete regimen.
Indications:
Ledihep 490mg is primarily indicated for:
- Chronic Hepatitis C: For the treatment of adults with genotype 1, 4, 5, or 6 HCV infection.
- Combination Therapy: Typically used in combination with Sofosbuvir, with or without ribavirin, depending on the patient's medical history and HCV genotype.
Mechanism of Action:
Ledipasvir works by inhibiting the NS5A protein of the hepatitis C virus. The NS5A protein is essential for the virus’s replication and assembly. By binding to this protein, Ledihep prevents the replication of the virus and helps reduce viral load, ultimately leading to viral clearance. In combination with Sofosbuvir, which inhibits the NS5B polymerase enzyme, Ledihep helps to effectively control and treat HCV infection.
Dosage and Administration:
- Recommended Dose: The standard dose is 490mg once daily, taken orally with or without food.
- Administration: Ledihep 490mg tablet should be taken as a whole with water. Do not crush, chew, or break the tablet.
- Missed Dose: If a dose is missed, it should be taken as soon as possible unless it’s almost time for the next dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, and diarrhea.
Serious side effects may include: - Liver damage: Particularly in patients with cirrhosis.
- Reactivation of hepatitis B: In patients co-infected with hepatitis B.
- Bradycardia: Especially when used with certain other medications.
Precautions:
- Hepatic Impairment: Dose adjustments may be required in patients with liver issues.
- Pregnancy: The safety of Ledihep during pregnancy has not been established; consult a healthcare provider.
- Drug Interactions: Inform your doctor of all medications you are taking to avoid harmful drug interactions.
Storage:
Store Ledihep 490mg at room temperature (20°C to 25°C), away from moisture, light, and out of reach of children.
Conclusion:
Ledihep 490mg is a key treatment option for chronic hepatitis C when used in combination with Sofosbuvir. By inhibiting the NS5A protein, it reduces viral replication, improving the chances of achieving a sustained virologic response (SVR). Regular monitoring for side effects and liver function is recommended during treatment.
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Hepcfix 60 mg Tablet
Product Price: Rs 2,000 / BottleGet Best Price
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Product Details:
| Dose/Strength | 60 mg |
| Pack Size | 28 Tablets in 1 Bottle |
| Composition (Salt) | Daclatasvir 60 mg |
| Brand Name | Hepcfix 60 mg |
| Manufactured By | Dr Reddy's Laboratories Ltd |
| Usage/Application | Hepatitis C virus infection |
Hepcfix 60 mg Tablet
Overview:
Hepcfix 60 mg Tablet is a combination medication containing Ledipasvir (90 mg) and Sofosbuvir (400 mg). It is used in the treatment of chronic hepatitis C virus (HCV) infection in adults. This medication targets and inhibits viral replication by interfering with key enzymes needed for the virus's life cycle. Ledipasvir inhibits the HCV NS5A protein, while Sofosbuvir inhibits the NS5B polymerase. Hepcfix is effective against all major HCV genotypes (1-6), and it is typically taken once daily.
Indications:
Hepcfix 60 mg Tablet is primarily indicated for the treatment of chronic hepatitis C in adults. It is used in patients with HCV genotypes 1-6, either as a monotherapy or in combination with other antiviral agents such as ribavirin or pegylated interferon in certain cases.
Mechanism of Action:
- Ledipasvir targets the NS5A protein, essential for HCV RNA replication and assembly of new viral particles.
- Sofosbuvir is a nucleotide analog that inhibits the NS5B polymerase, an enzyme responsible for viral RNA replication.
These two active ingredients work together to prevent HCV replication, ultimately reducing the viral load and improving liver function.
Dosage and Administration:
- Recommended Dose: The typical dose of Hepcfix 60 mg Tablet is one tablet taken once daily with or without food.
- Administration: Take the tablet whole with a glass of water. Do not chew, crush, or break the tablet.
- Missed Dose: If you miss a dose, take it as soon as you remember, unless it's almost time for your next dose. Do not double the dose to make up for a missed one.
Side Effects:
Common side effects may include:
- Fatigue, headache, nausea, diarrhea, and insomnia.
Serious side effects include: - Liver problems, severe allergic reactions, and bradycardia (especially when used with amiodarone).
Precautions:
- Renal Impairment: Use with caution in patients with severe kidney disease.
- Pregnancy and Breastfeeding: Sofosbuvir should not be used during pregnancy unless combined with ribavirin, which is contraindicated during pregnancy due to teratogenic risks.
- Drug Interactions: Hepcfix may interact with other medications, including certain HIV medications, antiarrhythmics, and anticonvulsants. Always inform your doctor about all other medications you're taking.
Monitoring:
Regular monitoring of liver function, HCV RNA levels, and kidney function is recommended during treatment. Periodic assessment of cardiac function may also be needed if Hepcfix is taken with amiodarone.
Storage:
Store Hepcfix 60 mg Tablet at room temperature (15°C to 30°C), away from light, moisture, and heat. Keep out of reach of children.
Conclusion:
Hepcfix 60 mg Tablet is a highly effective treatment for chronic hepatitis C, offering a simple, once-daily regimen. By inhibiting key enzymes involved in HCV replication, it helps to reduce viral load and improve liver function in infected individuals. Regular monitoring is essential to ensure treatment effectiveness and safety.
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Sofocure L 90 mg/400 mg Tablet
Product Price: Rs 6,350 / BottleGet Best Price
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Product Details:
| Dose/Strength | 90mg/400mg |
| Dose | 90 mg/400 mg |
| Pack Size | 10 Tablets in 1 Bottle |
| Salt Composition | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Brand Name | Sofocure L tablet |
| Manufactured | Emcure Pharmaceuticals Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Sofocure L 90mg/400mg Tablet
Overview:
Sofocure L is a combination tablet that contains Ledipasvir 90mg and Sofosbuvir 400mg. It is used to treat chronic hepatitis C virus (HCV) infection in adults. The combination of these two antiviral agents works by inhibiting key enzymes necessary for the replication of the HCV virus, reducing the viral load and preventing liver damage. Sofocure L is typically used for HCV genotype 1 infections, with or without cirrhosis, and in certain cases, it may be combined with other antiviral agents for treating other genotypes.
Indications:
Sofocure L is primarily indicated for:
- Chronic Hepatitis C Virus (HCV): Treatment of HCV genotype 1 infection in adults, with or without cirrhosis.
- Co-infection with HIV: For patients with both HIV and chronic HCV infection.
- Other HCV Genotypes: In some cases, Sofocure L is used in combination with other drugs to treat non-genotype 1 infections.
Mechanism of Action:
- Ledipasvir is an NS5A inhibitor that blocks the replication and assembly of the HCV virus by binding to the NS5A protein, a key protein required for the virus to replicate.
- Sofosbuvir is an NS5B polymerase inhibitor that inhibits the NS5B RNA polymerase, which is crucial for viral RNA replication. By blocking these enzymes, Sofocure L prevents HCV replication, allowing the immune system to clear the virus.
Dosage and Administration:
- Recommended Dose: The usual dose is one tablet of Sofocure L once daily, taken with or without food.
- Administration: Swallow the tablet whole; do not crush, chew, or break it.
- Missed Dose: If a dose is missed, take it as soon as possible unless it’s almost time for the next dose. Do not double the dose to make up for a missed dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, diarrhea, and insomnia.
Serious side effects may include: - Hepatotoxicity: Monitor liver function regularly during treatment.
- Bradycardia: When used with certain other medications, it may cause slow heart rate.
- Rash and allergic reactions such as swelling or difficulty breathing.
Precautions:
- Pregnancy: Sofocure L is not recommended during pregnancy unless clearly needed.
- Drug Interactions: Consult a healthcare provider about any other medications being taken, as interactions can occur.
- Renal Impairment: Dose adjustments may be needed in patients with severe kidney problems.
Storage:
Store Sofocure L tablets at room temperature (20°C to 25°C), away from light and moisture. Keep the tablets in the original packaging, and out of reach of children.
Conclusion:
Sofocure L (Ledipasvir/Sofosbuvir) is an effective treatment for chronic hepatitis C infection. It works by blocking critical viral enzymes, helping reduce viral replication and improve liver health. Regular monitoring for side effects, especially liver function, is essential during treatment.
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Virso 400 mg Tablet
Product Price: Rs 3,000 / BottleGet Best Price
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Product Details:
| Dose/Strength | 400 mg |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg |
| Brand Name | Virso 400 mg |
| Manufactured | Strides Acrolab Limited |
| Usage/Application | Chronic hepatitis C virus (HCV) Infection |
Virso 400mg Tablet
Overview:
Virso 400mg Tablet contains Sofosbuvir 400mg, an antiviral medication used primarily to treat chronic hepatitis C virus (HCV) infection in adults. Sofosbuvir is a nucleoside analog inhibitor of the NS5B RNA polymerase, an enzyme essential for the replication of the HCV virus. By blocking this enzyme, Virso prevents the virus from replicating, reducing the viral load, and helping to prevent liver damage associated with chronic hepatitis C.
Indications:
Virso 400mg Tablet is indicated for:
- Chronic Hepatitis C: Treatment of HCV genotype 1, 2, 3, and 4 infections in adults.
- Co-infection with HIV: Used in combination with other antivirals in patients co-infected with HIV and HCV.
Mechanism of Action:
Sofosbuvir, the active ingredient in Virso, inhibits the NS5B RNA polymerase, a key enzyme involved in the replication of the hepatitis C virus. By blocking this enzyme, Sofosbuvir halts viral RNA synthesis, preventing further replication of the virus and allowing the immune system to control and clear the infection more effectively.
Dosage and Administration:
- Recommended Dose: The usual dose is one 400mg tablet once daily, with or without food.
- Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
- Missed Dose: If you miss a dose, take it as soon as possible, unless it’s close to your next dose. Do not take two doses at the same time.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, insomnia, and anemia.
Serious side effects may include: - Hepatotoxicity: Liver function should be monitored regularly.
- Bradycardia: Slower heart rate may occur when taken with certain medications.
- Allergic reactions: Rare, but may include rash, swelling, or difficulty breathing.
Precautions:
- Pregnancy: Virso is not recommended during pregnancy unless clearly needed.
- Drug Interactions: Inform your doctor of all medications you are currently taking, as interactions can occur.
- Renal Impairment: Patients with severe kidney dysfunction may require dose adjustments.
Storage:
Store Virso 400mg Tablet at room temperature (20°C to 25°C), away from light and moisture. Keep the tablet in its original packaging and out of reach of children.
Conclusion:
Virso 400mg Tablet is an effective antiviral treatment for chronic hepatitis C. By inhibiting the NS5B RNA polymerase, it prevents viral replication and aids in liver health. Regular monitoring for side effects and liver function is essential during treatment.
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Abamune L 600 mg/300 mg Tablet
Product Price: Rs 2,000 / BottleGet Best Price
Product Brochure
Product Details:
| Packaging Size | 30 Tablets |
| Composition (salt) | Abacavir 600 mg + Lamivudine 300 mg |
| Brand Name | Abamune-L Tablet |
| Manufracturer | Cipla Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
| Variant | Abamune-L |
| Dose/Strength | 600mg+300mg |
Abamune L 600 mg/300 mg Tablet
Overview:
Abamune L is a combination tablet that contains Lamivudine (300 mg) and Abacavir (600 mg). It is used in the treatment of Human Immunodeficiency Virus (HIV) infection. This combination is a part of antiretroviral therapy (ART), which works by inhibiting the replication of the virus, improving immune function, and reducing the risk of HIV transmission. Both Abacavir and Lamivudine are nucleoside reverse transcriptase inhibitors (NRTIs) that target HIV's reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA.
Indications:
Abamune L 600 mg/300 mg Tablet is indicated for the treatment of:
- HIV Infection: As part of combination antiretroviral therapy for adults and children over the age of 12 years.
- Prevention of HIV Transmission: When used as part of a complete treatment regimen, it helps reduce the risk of transmission in HIV-positive individuals.
Mechanism of Action:
Abacavir and Lamivudine, the active ingredients in Abamune L, work by inhibiting the reverse transcriptase enzyme, an enzyme required by the HIV virus to replicate. By blocking this enzyme, Abamune L prevents the virus from making DNA copies of its RNA genome, effectively halting the replication process, reducing the viral load, and improving the immune system's ability to fight infections.
Dosage and Administration:
- Recommended Dose: The standard dose is one tablet (600 mg Abacavir + 300 mg Lamivudine) taken once daily.
- Administration: Take the tablet with or without food, swallowed whole with water.
- Missed Dose: If a dose is missed, take it as soon as possible unless it is near the time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Headache, nausea, fatigue, and dizziness.
Serious side effects may include: - Hypersensitivity Reactions: Abacavir can cause a serious allergic reaction, which may include fever, rash, and difficulty breathing.
- Lactic Acidosis: A rare but serious side effect involving the accumulation of lactic acid in the blood.
- Hepatic Toxicity: Liver enzyme elevation, jaundice, or other liver issues.
Precautions:
- Allergic Reaction: If you experience any signs of an allergic reaction to Abacavir, stop the medication immediately and seek medical help.
- Liver Disease: Patients with liver issues may need adjusted doses.
- Pregnancy: Consult a doctor before use during pregnancy.
- Drug Interactions: Inform your doctor about all other medications you are taking.
Storage:
Store Abamune L at room temperature (20°C to 25°C), away from moisture and heat. Keep it in its original packaging, out of the reach of children.
Conclusion:
Abamune L 600 mg/300 mg Tablet is an effective treatment for HIV infection. By inhibiting the replication of HIV, it helps control the virus, improve immune function, and reduce transmission risk. Regular monitoring for side effects is recommended to ensure safety.
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Sovihep V Tablets
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Dose/Strength | 400 mg/100 mg |
| Pack Size | 28 Tablets in Bottle |
| Salt Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Brand Name | Sovihep V tablet |
| Manufactured By | Zydus Cadila |
| Uses/Application | Chronic hepatitis C virus (HCV) infection |
Sovihep V Tablets
Overview:
Sovihep V Tablets is a fixed-dose combination medication used to treat chronic hepatitis C infection. The tablet contains two active ingredients: Sofosbuvir (400 mg) and Velpatasvir (100 mg). Both are direct-acting antivirals (DAAs) that work by targeting and inhibiting the hepatitis C virus (HCV) at different stages of its lifecycle. Sofosbuvir inhibits the viral RNA polymerase (NS5B), while Velpatasvir inhibits the NS5A protein, which is critical for HCV replication. Together, these medications effectively treat all HCV genotypes.
Indications:
Sovihep V Tablets is indicated for the treatment of:
- Chronic Hepatitis C: For adults with chronic HCV infection of any genotype, with or without cirrhosis. It is often used in combination with ribavirin in some cases, depending on the patient’s medical history and genotype.
Mechanism of Action:
- Sofosbuvir: A nucleotide analog inhibitor, blocks the NS5B polymerase, preventing HCV RNA replication.
- Velpatasvir: An NS5A inhibitor, prevents the assembly of the replication complex, disrupting the viral life cycle.
This dual-action approach significantly reduces viral load and helps achieve a sustained virologic response (SVR), leading to viral eradication.
Dosage and Administration:
- Recommended Dose: The standard dose is one tablet (400mg Sofosbuvir/100mg Velpatasvir) taken once daily.
- Administration: The tablet should be taken with or without food and swallowed whole.
- Missed Dose: If a dose is missed, it should be taken as soon as possible unless the next dose is close. Do not take two doses at once.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, and diarrhea.
Serious side effects may include: - Hepatitis reactivation in patients co-infected with HBV.
- Severe liver toxicity, especially in patients with cirrhosis.
- Rash or allergic reactions in some individuals.
Precautions:
- Liver Disease: Regular monitoring of liver function is recommended.
- Pregnancy: If co-administered with ribavirin, pregnancy should be avoided.
- Drug Interactions: May interact with other drugs that affect liver enzyme metabolism.
Storage:
Store Sovihep V Tablets at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion:
Sovihep V Tablets is a highly effective treatment for chronic hepatitis C, offering a once-daily regimen with a good safety profile. Monitoring liver function and possible drug interactions is important for patient safety during treatment.
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Indinavir Indivan 400 mg Tablets
Product Price: Rs 200 / BottleGet Best Price
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Product Details:
| Dose Strength | 400 mg |
| Composition | Indinavir 400 mg |
| Packaging Size | 30 Tablets In 1 Bottle |
| Brand | Indivan 400 mg Tablets |
| Manufactured by | Cipla Ltd |
| Treatment | Ongoing hepatitis B infection (HBV) contamination |
Indinavir (Indivan) 400 mg Tablets
Overview:
Indinavir (brand name Indivan) is an antiretroviral medication used to treat HIV (Human Immunodeficiency Virus) infection. It is a protease inhibitor that works by inhibiting the HIV protease enzyme, which is crucial for the maturation of infectious viral particles. By blocking this enzyme, Indinavir prevents the replication of the virus, helping to reduce the viral load, improve immune function, and reduce the risk of HIV transmission. Indinavir is typically used in combination with other antiretroviral drugs as part of a combination therapy.
Indications:
Indinavir 400 mg Tablets are indicated for:
- HIV Infection: Used as part of combination therapy to treat HIV-1 infection in adults and children above 2 years of age.
Mechanism of Action:
Indinavir inhibits the activity of the HIV protease enzyme, which is responsible for processing viral proteins into their mature, functional form. By blocking this enzyme, Indinavir prevents the production of mature, infectious viral particles, thereby reducing the viral load in the body and helping to control the progression of HIV.
Dosage and Administration:
- Recommended Dose: The typical dose for adults is 800 mg every 8 hours, administered along with other antiretroviral agents. For pediatric patients, the dose depends on the weight and clinical condition.
- Administration: Indinavir should be taken on an empty stomach or with a light meal. The tablet should be swallowed whole with water.
- Missed Dose: If a dose is missed, take it as soon as you remember unless it's almost time for the next dose. Do not double doses.
Side Effects:
Common side effects include:
- Headache, nausea, diarrhea, fatigue, and abdominal pain.
Serious side effects may include: - Kidney stones: Indinavir can cause kidney problems, including kidney stones.
- Liver toxicity: Hepatotoxicity or liver damage, with signs such as yellowing of the skin or eyes.
- Hyperglycemia: Elevated blood sugar, especially in diabetic patients.
- Lipodystrophy: Redistribution of body fat, including fat accumulation in certain areas.
Precautions:
- Liver Disease: Use with caution in patients with liver disease. Regular liver function tests are necessary.
- Kidney Issues: Adequate hydration is important to avoid kidney stones and other kidney issues.
- Pregnancy: Indinavir is a Category C drug, meaning it should only be used in pregnancy if clearly needed.
Monitoring:
- Kidney Function: Regular monitoring for kidney function and hydration is essential.
- Blood Glucose: Blood sugar levels should be monitored regularly, particularly in diabetic patients.
- Liver Function: Liver enzymes should be checked periodically.
Storage:
Store Indinavir 400 mg Tablets at room temperature (20°C to 25°C), away from moisture and heat. Keep it in its original packaging and out of the reach of children.
Conclusion:
Indinavir 400 mg Tablets is an important part of combination therapy for the treatment of HIV infection. While effective in reducing viral load, it may cause side effects, especially kidney or liver issues, so regular monitoring is essential to ensure safety and treatment success.
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Revolade Eltrombopag 50 mg Tablet
Product Price: Rs 5,500 / BoxGet Best Price
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Product Details:
| Strength | 50 mg |
| Packaging size | 28 Tablets in 1 Box |
| Composition | Eltrombopag 50 mg |
| Brand | Revolade 50 mg |
| Manufactured By | GSK - Glaxo Smith Kline |
| Treatment | Low platelet count because of ITP or HCV contamination |
Revolade Eltrombopag 50 mg Tablet
Overview:
Revolade (Eltrombopag) is an oral medication used to treat thrombocytopenia (low platelet count) in various conditions, including chronic immune thrombocytopenia (ITP), severe aplastic anemia, and hepatitis C-associated thrombocytopenia. Eltrombopag is a thrombopoietin receptor agonist that stimulates the production of platelets by activating the thrombopoietin receptor (Mpl) on bone marrow cells. This leads to increased platelet production in the body.
Indications:
Revolade 50 mg is primarily indicated for:
- Chronic Immune Thrombocytopenia (ITP): In patients who have not responded to corticosteroids, immunoglobulins, or splenectomy.
- Severe Aplastic Anemia: In combination with standard immunosuppressive therapy.
- Hepatitis C: To treat thrombocytopenia associated with hepatitis C infection in patients undergoing antiviral therapy.
Mechanism of Action:
Eltrombopag works by binding to the thrombopoietin receptor (Mpl) on hematopoietic cells in the bone marrow, stimulating the production of platelets. This increases the platelet count, which helps to reduce the risk of bleeding in patients with low platelet levels.
Dosage and Administration:
- Recommended Dose: For ITP, the typical starting dose is 50 mg once daily. The dose may be adjusted based on platelet response.
- Administration: Take Revolade 50 mg tablet orally once a day, with or without food. Swallow the tablet whole. Do not crush or chew.
- Missed Dose: If a dose is missed, take it as soon as possible unless it's near the time for the next dose. Do not double doses.
Side Effects:
- Common Side Effects: Headache, fatigue, nausea, and diarrhea.
- Serious Side Effects: Liver enzyme abnormalities, thrombosis, and cataracts. Regular liver function monitoring is recommended.
Precautions:
- Liver Function: Eltrombopag can increase liver enzymes, so liver function should be closely monitored.
- Thrombosis: The risk of blood clots may be increased, especially when combined with other pro-thrombotic agents.
- Pregnancy: Revolade is not recommended during pregnancy unless the benefit outweighs the risk.
Storage:
Store Revolade 50 mg tablets at room temperature (15°C to 30°C), away from light and moisture.
Conclusion:
Revolade (Eltrombopag) is a valuable treatment for thrombocytopenia associated with conditions like ITP and severe aplastic anemia. Proper monitoring for side effects, especially liver function, is important for patient safety.
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Hepcdac Daclatasvir 60 Mg Tablets
Product Price: Rs 2,000 / BottleGet Best Price
Product Brochure
Product Details:
| Dose/Strength | 60 mg |
| Pack Size | 28 Tablets in 1 Bottle |
| Composition (Salt) | Daclatasvir 60 mg |
| Brand Name | Hepcdac 60 mg |
| Manufactured By | Cipla Ltd |
| Usage/Application | Hepatitis |
Hepcdac Daclatasvir 60 mg Tablets
Overview:
Hepcdac contains Daclatasvir, a direct-acting antiviral (DAA) used in the treatment of chronic hepatitis C virus (HCV) infection. Daclatasvir works by inhibiting the NS5A protein, a key component that the virus needs for replication. By blocking this protein, Hepcdac helps prevent the replication of the virus, lowering viral load and improving liver function in individuals infected with HCV.
Indications:
Hepcdac 60 mg is indicated for the treatment of hepatitis C in adults. It is commonly used in combination with Sofosbuvir, and may also be used with Ribavirin in specific cases. It is effective in treating HCV genotypes 1-4 and can be used in both naive and treatment-experienced patients. This medication is suitable for patients with or without cirrhosis.
Mechanism of Action:
Daclatasvir acts by inhibiting the NS5A protein, which is crucial for the replication and assembly of the HCV virus. By blocking the NS5A protein, Hepcdac stops viral replication, leading to reduced viral load and facilitating recovery from the infection.
Dosage and Administration:
- Recommended dose: 60 mg once daily.
- Administration: The tablet can be taken with or without food. It should be swallowed whole with water.
- Missed dose: If you miss a dose, take it as soon as you remember, unless it is time for the next dose.
Side Effects:
- Common side effects: Fatigue, headache, nausea, and diarrhea.
- Serious side effects: Liver problems, jaundice, allergic reactions (rash, breathing difficulty), and dark urine. Consult a doctor if any of these occur.
Precautions:
- Liver disease: Regular monitoring of liver function is important, especially for patients with cirrhosis.
- Drug interactions: Hepcdac may interact with other medications. Always inform your doctor of any other drugs you are taking.
- Pregnancy and breastfeeding: Consult a healthcare provider before using Hepcdac during pregnancy or breastfeeding.
Storage:
Store at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion:
Hepcdac 60 mg is a highly effective treatment for hepatitis C when used with other antiviral medications. Regular monitoring and adherence to the prescribed regimen will improve treatment outcomes.
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