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Providing you the best range of eltrombopag olamine tablets 25 mg (trombopag 50mg), spegra dolutegravir emtricitabine tenofovir alafenamide tablet, viraday tablet emtricitabine 200 mg + tenofovir disoproxil fumarate 300 mg + efavirenz 600 mg, ricovir em 200 mg/300 mg, trioday tablet (lamivudine 300 mg + tenofovir disoproxil fumarate 300 mg + efavirenz 600 mg) and 1200mg telura tablet with effective & timely delivery.
Eltrombopag Olamine Tablets 25 mg (Trombopag 50mg)
Product Price: Rs 1,250 / BoxGet Best Price
Product Brochure
Product Details:
| Brand | Trombopag 50 mg |
| Composition | Eltrombopag 50 mg |
| Packaging size | 7 Tablets in 1 Strip |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Low Platelet Count And Severe Aplastic Anaemia (SAA) |
| Strength | 25 mg |
Eltrombopag Olamine Tablets 50 mg
Overview:Eltrombopag Olamine 25 mg Tablets contain Eltrombopag, a thrombopoietin receptor agonist used to treat thrombocytopenia (low platelet count). It stimulates the production of platelets in the bone marrow. Eltrombopag is indicated for the treatment of chronic immune thrombocytopenia (ITP), severe aplastic anemia, and hepatitis C-related thrombocytopenia (low platelet count due to hepatitis C). By activating the thrombopoietin receptor (c-Mpl) on megakaryocytes and hematopoietic stem cells, Eltrombopag promotes platelet production and increases platelet count.
Indications:- Chronic Immune Thrombocytopenia (ITP): For adults and children (≥1 year) with chronic ITP who have not responded to prior treatments (e.g., corticosteroids, immunoglobulins, or splenectomy).
- Severe Aplastic Anemia: Used in combination with standard immunosuppressive therapy for severe aplastic anemia.
- Hepatitis C-Related Thrombocytopenia: In patients with chronic hepatitis C to increase platelet counts, enabling the use of antiviral therapy.
Eltrombopag binds to and activates the thrombopoietin receptor (c-Mpl) on bone marrow cells, specifically megakaryocytes. This stimulates the production and release of platelets, leading to an increase in platelet counts in the bloodstream.
Dosage and Administration:- Adult dose for ITP: 50 mg once daily (adjusted based on platelet count).
- Pediatric dose: Typically ranges from 25 mg to 50 mg daily, based on weight and age. Eltrombopag should be taken on an empty stomach, at least 2 hours after food or 1 hour before food. It should be swallowed whole with water.
- Common: Fatigue, headache, nausea, diarrhea, and insomnia.
- Serious: Hepatotoxicity (liver dysfunction), thrombotic events (e.g., DVT, PE), and bone marrow disorders (e.g., myelodysplastic syndromes or leukemia). Liver function and platelet counts should be monitored regularly.
- Liver disease: Monitor liver function (ALT, AST) during treatment.
- Pregnancy: Category C – Use only if benefits outweigh risks. Avoid breastfeeding.
- Drug interactions: Inform your healthcare provider about other medications, especially those affecting liver enzymes.
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Eltrombopag Olamine 50 mg Tablets are an effective treatment for thrombocytopenia associated with ITP, severe aplastic anemia, and hepatitis C. Regular monitoring of platelet counts, liver function, and complete blood counts is essential for safe and effective use.
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Spegra Dolutegravir Emtricitabine Tenofovir Alafenamide Tablet
Product Price: Rs 2,000 / BottleGet Best Price
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Product Details:
| Usage | HIV Treatment |
| Strength | 50 mg/200 mg/25 mg |
| Dose Strength | 50 mg/200 mg/25 mg |
| Brand Name | Spegra Tablets |
| Treatment | HIV-1 Infection |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Dolutegravir 50 mg + Emtricitabine 200 mg + Tenofovir Alafenamide 25 mg |
| Manufacturer | Emcure Pharmaceuticals Ltd |
Spegra Dolutegravir Emtricitabine Tenofovir Alafenamide Tablet
Overview:
Spegra is a combination medication that contains Dolutegravir, Emtricitabine, and Tenofovir Alafenamide. It is used for the treatment of HIV-1 infection in adults and pediatric patients. Dolutegravir is an integrase strand transfer inhibitor (INSTI), Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI), and Tenofovir Alafenamide is a nucleotide reverse transcriptase inhibitor (NTRI). This combination works by preventing the replication of the HIV virus in the body, thus reducing the viral load and increasing the number of CD4 cells (immune cells).
Indications:
Spegra is indicated for:
- HIV-1 infection: For the treatment of HIV-1 in adults and children (weighing at least 25 kg) as part of a combination therapy.
Mechanism of Action:
- Dolutegravir: Inhibits the integrase enzyme, preventing viral DNA from integrating into the host cell's genome.
- Emtricitabine: Inhibits reverse transcriptase, preventing the transcription of viral RNA into DNA.
- Tenofovir Alafenamide: Inhibits reverse transcriptase, preventing the replication of viral RNA.
This combined action suppresses the HIV virus and reduces the chances of developing resistance to treatment.
Dosage and Administration:
- Recommended Dose: The usual dose of Spegra is one tablet once daily, taken orally with or without food.
- Missed Dose: If a dose is missed, take it as soon as possible unless it's almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects may include:
- Headache, diarrhea, nausea, and fatigue.
- Serious side effects may include:
- Liver issues: Hepatitis, jaundice.
- Renal issues: Kidney dysfunction or increased creatinine levels.
- Hypersensitivity reactions: Rashes or breathing difficulties.
Precautions:
- Hepatic Impairment: Caution is needed in patients with liver disease. Liver function should be monitored.
- Renal Impairment: Regular kidney function tests are recommended.
- Pregnancy: Spegra is not recommended during pregnancy unless the benefit outweighs the risk. Use appropriate contraception.
Storage:
Store Spegra tablets at room temperature (15°C to 30°C), away from moisture and heat. Keep out of reach of children.
Conclusion:
Spegra is an effective once-daily combination therapy for managing HIV-1 infection, helping reduce viral load and improving immune function. Regular monitoring for side effects, particularly liver and renal function, is necessary for safe use.
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Viraday Tablet Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg
Product Price: Rs 1,200 / BottleGet Best Price
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Product Details:
| Dose/Strength | 200mg/300mg/600mg |
| Pack Size | 30 tablets |
| Strength | 200 mg/300 mg/600 mg |
| Brand | Viraday |
| Packaging Size | 1x30Tablets |
| Composition | Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg |
| Brand Name | Viraday Tablet |
| Manufacturers | Cipla Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Viraday 110mg Tablet
Overview: Viraday is a combination medication used primarily in the treatment of HIV-1 infection. It contains three active ingredients: Tenofovir Disoproxil Fumarate (300 mg), Lamivudine (150 mg), and Efavirenz (600 mg). This combination works by inhibiting the reverse transcriptase enzyme, a key enzyme that HIV uses to replicate itself. By blocking this enzyme, Viraday helps lower the amount of HIV in the blood, improve the immune system's ability to fight infections, and reduce the risk of transmitting HIV to others.
Indications: Viraday 110mg Tablet is indicated for:
- HIV-1 Infection: Used as a part of combination antiretroviral therapy (ART) for adults and adolescents (aged 12 years or older) who are infected with HIV-1.
Mechanism of Action:
- Tenofovir Disoproxil Fumarate (TDF): An NRTI (nucleoside reverse transcriptase inhibitor) that inhibits reverse transcriptase, reducing HIV replication.
- Lamivudine (3TC): An NRTI that also blocks reverse transcriptase and prevents HIV replication.
- Efavirenz (EFV): A non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to the reverse transcriptase enzyme, further inhibiting viral replication.
Together, these medications work synergistically to suppress viral replication and improve immune function in HIV-infected patients.
Dosage and Administration:
- Recommended Dose: 1 tablet (110 mg) daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It's advised to take it at the same time every day for optimal results.
Side Effects:
- Common Side Effects: Dizziness, headache, nausea, fatigue, insomnia, and rash.
- Serious Side Effects: Liver toxicity, depression, suicidal thoughts, and severe allergic reactions. Regular monitoring of liver function is recommended.
Precautions:
- Liver Disease: Not recommended for patients with severe liver disease.
- Pregnancy: Avoid use during the first trimester due to potential harm to the fetus. Consult your doctor.
- Kidney Function: Regular kidney function tests are necessary.
Storage: Store at room temperature (15°C to 30°C), in a dry place, away from moisture and heat.
Conclusion: Viraday 110mg Tablet is an effective HIV treatment that combines three antiretroviral drugs to suppress viral replication. Regular monitoring of liver function and kidney health is recommended during treatment.
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Ricovir EM 200 mg/300 mg
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 200 mg/300 mg |
| Pack Size | 30 tablets |
| Strength | 200 mg/300 mg |
| Brand | Ricovir EM |
| Packaging Size | 1x30Tablets |
| Composition | Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg |
| Brand Name | Ricovir EM |
| Manufacturerd By | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | HIV Infection |
Ricovir EM 200mg/300mg Tablet
Overview: Ricovir EM is a combination antiretroviral medication used to treat HIV-1 infection. It contains two active ingredients: Lamivudine (200 mg) and Emtricitabine (300 mg). Both drugs belong to the class of nucleoside reverse transcriptase inhibitors (NRTIs), which help block the replication of the HIV virus. By reducing the amount of HIV in the blood and improving the immune system, Ricovir EM plays a crucial role in managing HIV infection.
Indications: Ricovir EM 200 mg/300 mg Tablet is indicated for:
- HIV-1 Infection: It is used as a part of combination antiretroviral therapy (ART) for the treatment of HIV-1 infection in adults and pediatric patients who weigh at least 35 kg.
Mechanism of Action:
- Lamivudine (200 mg): A nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, thereby preventing HIV from replicating in the body.
- Emtricitabine (300 mg): Similar to lamivudine, emtricitabine blocks the reverse transcriptase enzyme, preventing the replication of the HIV virus.
Together, these medications help control the HIV virus, reducing viral load and enhancing the effectiveness of the immune system.
Dosage and Administration:
- Recommended Dose: One tablet of Ricovir EM 200 mg/300 mg once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water, at the same time each day for best results.
Side Effects:
- Common Side Effects: Headache, fatigue, nausea, diarrhea, and dizziness.
- Serious Side Effects: Lactic acidosis, liver toxicity, pancreatitis, and severe allergic reactions. Liver function should be monitored regularly.
Precautions:
- Liver Disease: Caution in patients with a history of liver problems.
- Pregnancy: Consult a healthcare provider before use during pregnancy.
- Kidney Function: Kidney function should be monitored during treatment.
Storage: Store Ricovir EM 200 mg/300 mg tablets at room temperature (15°C to 30°C), away from moisture and direct sunlight.
Conclusion: Ricovir EM 200 mg/300 mg Tablet is an effective combination treatment for HIV-1 infection, helping to suppress the virus and support the immune system. Regular monitoring of liver and kidney function is recommended during treatment.
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Trioday Tablet (Lamivudine 300 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg)
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/300 mg/600 mg |
| Pack Size | 30 tablets |
| Strength | 300 mg/300 mg/600 mg |
| Brand | Trioday |
| Packaging Size | 1x30Tablets |
| Composition | Efavirenz 600 mg + Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg |
| Brand Name | Trioday Tablet |
| Manufactured | Cipla Ltd |
| Treatment | HIV infection |
Trioday 1200mg Tablet
Overview: Trioday is a combination medication containing Tenofovir Disoproxil Fumarate (300 mg), Emtricitabine (200 mg), and Efavirenz (600 mg). It is used to treat HIV-1 infection and to prevent the progression of the virus in individuals diagnosed with HIV. The three active ingredients in Trioday work together to inhibit the replication of HIV, thereby helping to reduce the viral load and improve immune function in people living with HIV.
Indications: Trioday 1200mg Tablet is indicated for:
- HIV-1 Infection: As a part of a combination antiretroviral regimen in adults and children who weigh at least 35 kg.
Mechanism of Action:
- Tenofovir: A nucleoside reverse transcriptase inhibitor (NRTI) that blocks reverse transcriptase, the enzyme responsible for converting viral RNA into DNA, preventing viral replication.
- Emtricitabine: Another NRTI that works in a similar way to Tenofovir, further inhibiting reverse transcriptase and suppressing HIV replication.
- Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to the reverse transcriptase enzyme and prevents it from functioning, contributing to the inhibition of HIV replication.
Dosage and Administration:
- Recommended Dose: One Trioday 1200mg tablet once daily, taken orally.
- Administration: The tablet should be swallowed whole with or without food. It is recommended to take it at the same time each day.
Side Effects:
- Common Side Effects: Rash, dizziness, headache, nausea, fatigue, and diarrhea.
- Serious Side Effects: Liver toxicity, kidney problems, severe allergic reactions, and central nervous system effects such as depression or vivid dreams.
Precautions:
- Liver Disease: Regular liver function tests are recommended for patients with a history of liver problems.
- Pregnancy: Use during pregnancy should be considered only when necessary; consult a healthcare provider.
- Drug Interactions: Inform the doctor of any other medications being taken to avoid interactions.
Storage: Store Trioday 1200mg tablet at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion: Trioday 1200mg Tablet is an effective combination treatment for managing HIV-1 infection. It should be taken as prescribed, with regular medical check-ups for monitoring any side effects.
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1200mg Telura Tablet
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/300 mg/600 mg |
| Strength | 300 mg/300 mg/600 mg |
| Brand | Telura |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Lamivudine 300mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg |
| Brand Name | Telura Tablet |
| Manufacturers | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | Chronic hepatitis B virus (HBV) Infection |
Telura 1200mg Tablet
Overview:Telura is a medication that contains Telbivudine (1200 mg), an antiviral drug used primarily in the treatment of chronic hepatitis B (HBV). Telbivudine is a nucleoside analogue reverse transcriptase inhibitor (NRTI). It works by inhibiting the replication of the hepatitis B virus by blocking the reverse transcriptase enzyme, which is essential for the virus to replicate its genetic material.
Telura 1200mg tablets are specifically used to reduce the viral load in patients with chronic hepatitis B, improve liver function, and decrease the risk of complications like cirrhosis and liver cancer.
Indications:Telura 1200 mg Tablet is indicated for:
- Chronic Hepatitis B (HBV): Treatment of chronic hepatitis B infection in adults with evidence of active viral replication and liver damage.
Telbivudine, the active ingredient in Telura, works by inhibiting hepatitis B virus reverse transcriptase. This enzyme is required by HBV to replicate its viral genome. By blocking this enzyme, Telbivudine prevents the virus from replicating, thereby reducing the viral load, improving liver function, and slowing the progression of liver disease associated with chronic HBV infection.
Dosage and Administration:- Recommended Dose: The typical dose of Telura is 1200 mg once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It is important to take Telura at the same time each day to maintain consistent drug levels in the body.
-
Common Side Effects:
- Headache
- Fatigue
- Nausea
- Diarrhea
- Upper respiratory tract infections
-
Serious Side Effects:
- Lactic acidosis (a buildup of lactic acid in the blood)
- Hepatomegaly (enlarged liver) and steatosis (fatty liver)
- Peripheral neuropathy (nerve damage, causing pain, tingling, or weakness)
- Muscle pain or weakness (myopathy)
Regular monitoring of liver function and kidney health is recommended to detect any adverse reactions early.
- Kidney Impairment: Telura should be used with caution in patients with pre-existing kidney disease, as renal function may be impacted. Regular monitoring of kidney function (serum creatinine, eGFR) is advised.
- Liver Disease: Patients with severe liver dysfunction or cirrhosis should be monitored closely during treatment.
- Pregnancy: Discuss the use of Telura with your doctor if you are pregnant or planning to become pregnant. The medication is classified as Pregnancy Category C, meaning the risk to the fetus cannot be ruled out.
- Breastfeeding: Telbivudine is excreted in breast milk; therefore, consult your healthcare provider before breastfeeding.
Store Telura 1200 mg tablets at room temperature (15°C to 30°C), away from light and moisture. Keep the medication in its original packaging and out of reach of children.
Conclusion:Telura 1200mg Tablet is an effective treatment for chronic hepatitis B (HBV). It helps reduce the viral load and improves liver function, decreasing the risk of complications like cirrhosis or liver cancer. Adherence to the prescribed dosage, regular monitoring of liver and kidney function, and consultation with your healthcare provider are essential for optimal treatment outcomes.
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Vonaday Tablet Lamivudine & Tenofovir Disoproxil Fumarate & Efavirenz
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 300 mg/300 mg/600 mg |
| Strength | 300 mg/300 mg/600 mg |
| Brand | Vonaday |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition (salt) | Lamivudine 300 mg & Tenofovir disoproxil fumarate 300 mg & Efavirenz 600 mg |
| Brand Name | Vonaday Tablets |
| Manufacturers | Cipla Ltd |
| Treatment | HIV infection |
Vonaday 1200mg Tablet
Overview: Vonaday is a combination medication used primarily for the treatment of HIV-1 infection. It contains three active ingredients: Tenofovir Disoproxil Fumarate (300 mg), Emtricitabine (200 mg), and Efavirenz (600 mg). This combination therapy helps control the replication of HIV in the body by inhibiting the activity of HIV enzymes essential for its replication.
Indications: Vonaday 1200mg Tablet is indicated for:
- HIV-1 Infection: For adults and pediatric patients (weighing at least 35 kg) as part of a combination antiretroviral regimen.
Mechanism of Action:
- Tenofovir: A nucleoside reverse transcriptase inhibitor (NRTI), which blocks reverse transcriptase, preventing the conversion of viral RNA into DNA and inhibiting viral replication.
- Emtricitabine: Another NRTI that works by inhibiting the reverse transcriptase enzyme, reducing the ability of the virus to multiply.
- Efavirenz: A non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds to and deactivates the reverse transcriptase enzyme, further hindering HIV replication.
Dosage and Administration:
- Recommended Dose: Take one Vonaday 1200mg tablet once daily, preferably at the same time each day.
- Administration: Swallow the tablet whole with or without food. Ensure proper hydration and consistency in dosing.
Side Effects:
- Common Side Effects: Nausea, headache, dizziness, fatigue, insomnia, and rash.
- Serious Side Effects: Hepatotoxicity, renal impairment, depression, severe allergic reactions, and neuropsychiatric symptoms such as vivid dreams or mood changes.
Precautions:
- Liver Disease: Monitor liver function, especially for patients with pre-existing liver conditions.
- Pregnancy and Breastfeeding: Consult your healthcare provider before using Vonaday during pregnancy or breastfeeding.
- Drug Interactions: Be aware of potential interactions with other medications. Inform your doctor about all other treatments.
Storage: Store Vonaday 1200mg tablet at room temperature (15°C to 30°C), away from moisture and direct light. Keep out of reach of children.
Conclusion: Vonaday 1200mg Tablet is a highly effective treatment for managing HIV-1 infection. Proper adherence to the prescribed regimen and regular medical monitoring are important for achieving optimal outcomes.
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Vemlidy Tenofovir Alafenamide 25 mg Tablets
Product Price: Rs 1,200 / BottleGet Best Price
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Product Details:
| Strength | 25 mg |
| Usage | Hepatitis B |
| Dose Strength | 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Composition | Tenofovir Alafenamide 25 mg |
| Brand Name | Vemlidy Tablets |
| Treatment | Ongoing hepatitis B infection (HBV) contamination |
| Manufacturer | Gilead Science Ltd |
Vemlidy Tenofovir Alafenamide 25mg Tablets
Overview: Vemlidy (Tenofovir Alafenamide) is an antiviral medication used to treat chronic hepatitis B virus (HBV) infection in adults and pediatric patients aged 12 years and older. It is a nucleotide reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HBV virus. By blocking this enzyme, Tenofovir Alafenamide reduces the viral load in the body, helping to prevent liver damage, cirrhosis, and liver failure.
Indications: Vemlidy 25mg is indicated for the treatment of chronic hepatitis B (HBV) in adult and pediatric patients who are HBV DNA positive and have compensated liver disease. It is used to reduce the amount of the virus in the blood and to improve liver function. Vemlidy is not a cure for HBV but can help control the infection over time.
Mechanism of Action: Tenofovir Alafenamide is a prodrug of Tenofovir, which is phosphorylated inside the cell to its active form. It inhibits the reverse transcriptase enzyme of the HBV virus, preventing viral replication. This reduces the amount of HBV in the liver and blood, improving liver function and decreasing the risk of liver damage.
Dosage and Administration:
- Recommended dose: One 25mg tablet once daily, with or without food.
- Administration: Swallow the tablet whole with water. Do not crush or chew.
- Missed dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose.
Side Effects:
- Common side effects: Headache, fatigue, nausea, and abdominal pain.
- Serious side effects: Renal impairment, lactic acidosis, hepatomegaly, and steatosis. Regular monitoring of kidney function is recommended.
Precautions:
- Renal function: Regular monitoring of renal function and serum phosphate is advised, especially in patients with pre-existing kidney conditions.
- Pregnancy: Consult with a healthcare provider before use during pregnancy or breastfeeding.
Storage: Store Vemlidy at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion: Vemlidy 25mg is an effective treatment for chronic hepatitis B. With regular monitoring, it can significantly reduce viral load and improve liver function in patients with HBV infection.
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Trombopag 25mg Tablet
Product Price: Rs 280 / BoxGet Best Price
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Product Details:
| Strength | 25 mg |
| Pack Size | 28 Tablets |
| Brand | Trombopag 25 mg |
| Composition | Eltrombopag Olamine 25 mg |
| Packaging size | 4*7 Tablets |
| Manufactured By | Natco 25 mg |
| Treatment | Severe Aplastic Anemia |
Trombopag 25mg Tablet
Overview:
Trombopag 25mg is an oral medication used to treat chronic immune thrombocytopenia (ITP) and severe aplastic anemia (SAA). It is a thrombopoietin receptor agonist that stimulates the production of platelets in the bone marrow. By binding to the thrombopoietin receptor, Trombopag promotes the production of new platelets, helping to prevent bleeding and reduce the need for platelet transfusions in patients with low platelet counts.
Indications:
Trombopag 25mg Tablet is indicated for:
- Chronic Immune Thrombocytopenia (ITP): To increase platelet count in adult patients who have had an insufficient response to other treatments such as corticosteroids or immunoglobulins.
- Severe Aplastic Anemia (SAA): Used in combination with other therapies for patients with SAA who have not responded to immunosuppressive treatment.
Mechanism of Action:
Trombopag is a synthetic thrombopoietin receptor agonist. It binds to and activates the thrombopoietin receptor (MPL) on the surface of hematopoietic progenitor cells in the bone marrow. This stimulation increases the production of platelets and other blood cells, improving platelet counts and reducing the risk of bleeding in conditions like ITP and SAA.
Dosage and Administration:
- Recommended Dose: The usual starting dose is 25mg once daily. For ITP, the dose may be adjusted based on the platelet count and individual response.
- Administration: Trombopag 25mg is taken orally, with or without food. The tablet should be swallowed whole and not chewed or crushed.
- Missed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose.
Side Effects:
Common side effects include:
- Headache, nausea, fatigue, and diarrhea.
Serious side effects may include: - Liver toxicity: Elevated liver enzymes or jaundice.
- Thrombosis: Increased risk of blood clots.
- Bone Marrow Suppression: Can cause low white blood cell counts, leading to infections.
Precautions:
- Liver Function: Regular monitoring of liver enzymes is essential.
- Thrombosis Risk: Caution in patients with a history of blood clots.
- Pregnancy and Breastfeeding: Use only if the benefits outweigh the risks.
Storage:
Store Trombopag 25mg Tablets at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Trombopag 25mg Tablet is an effective treatment for chronic ITP and severe aplastic anemia. Monitoring for liver function and the risk of blood clots is essential during treatment.
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Valten 300 mg Tablet
Product Price: Rs 450 / BottleGet Best Price
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Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Valten |
| Packaging Size | 1x30Tablets |
| Composition | Tenofovir Disoproxil Fumarate 300 mg |
| Brand Name | Valten 300 mg |
| Manufacturers | Wockhardt Ltd |
| Treatment | Chronic Hepatitis B Virus (HBV) Infection |
Valten 300mg Tablet
Overview: Valten 300mg Tablet is a medication primarily used for the management of hypertension (high blood pressure) and heart failure. It contains Valsartan, an angiotensin II receptor antagonist (ARB). Valsartan works by blocking the action of angiotensin II, a substance that narrows blood vessels and raises blood pressure. By blocking this action, Valten helps relax blood vessels, lower blood pressure, and reduce the risk of complications like stroke, heart attack, and kidney problems.
Indications: Valten 300mg Tablets are indicated for:
- Hypertension: To lower blood pressure in adults and children over 6 years old.
- Heart Failure: In patients with symptomatic heart failure to improve survival and reduce hospitalizations.
- Post-Heart Attack: For the treatment of heart attack patients with reduced left ventricular function.
Mechanism of Action: Valsartan, the active ingredient in Valten, is an angiotensin II receptor blocker (ARB). It binds to and blocks the angiotensin II receptors, thereby inhibiting the constriction of blood vessels. This leads to vasodilation (widening of blood vessels), which reduces blood pressure and helps the heart pump more efficiently.
Dosage and Administration:
- Hypertension: The typical dose is 80-320 mg once daily, depending on the severity of the condition.
- Heart Failure and Post-Heart Attack: The usual dose is 40-160 mg once daily, titrated based on patient tolerance.
- Administration: Take Valten 300mg Tablet orally, with or without food, at the same time each day.
Side Effects:
- Common Side Effects: Dizziness, headache, fatigue, and abdominal pain.
- Serious Side Effects: Low blood pressure, elevated potassium levels (hyperkalemia), kidney problems, and allergic reactions.
Precautions:
- Kidney Function: Monitor renal function regularly during treatment.
- Pregnancy and Breastfeeding: Valten is contraindicated during pregnancy, especially in the second and third trimesters, as it may harm the fetus.
Storage: Store Valten 300mg Tablet at room temperature (20°C to 25°C), away from moisture and light.
Conclusion: Valten 300mg Tablet is an effective treatment for hypertension, heart failure, and post-heart attack management. It works by relaxing blood vessels and lowering blood pressure, helping reduce the risk of cardiovascular events and improving heart function.
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Velpaclear 400 Mg/100mg Tablets
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Strength | 400 mg+ 100 mg |
| Pack Size | 28 tablets |
| Brand | Velpaclear 100 mg/400 mg tablet |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Velpatasvir 100 mg + Sofosbuvir 400 mg |
| Manufactured By | Abbott |
| Treatment Of | Chronic hepatitis C virus (HCV) infection |
Velpaclear 400 mg/100 mg Tablets
Overview:
Velpaclear is a combination antiviral medication containing Sofosbuvir (400 mg) and Velpatasvir (100 mg). It is used for the treatment of chronic hepatitis C virus (HCV) infection in adults. Sofosbuvir is a nucleoside analog that inhibits HCV replication, while Velpatasvir is a NS5A inhibitor that interferes with the HCV lifecycle. Together, these two components work to reduce the viral load and improve the chances of curing hepatitis C.
Indications:
Velpaclear is indicated for the treatment of chronic hepatitis C virus infection in adult patients. It is effective against HCV genotypes 1, 2, 3, 4, 5, and 6 and can be used for treatment-naive patients or those who have previously failed other treatments.
Mechanism of Action:
- Sofosbuvir blocks the NS5B RNA-dependent RNA polymerase enzyme, which is necessary for the replication of the hepatitis C virus.
- Velpatasvir targets the NS5A protein, preventing the virus from assembling and releasing new virions. By combining both, Velpaclear effectively suppresses HCV replication.
Dosage and Administration:
- The typical dosage of Velpaclear is one tablet daily, taken with or without food.
- Treatment duration is generally 12 weeks, but may vary based on HCV genotype, prior treatment history, and liver function.
Side Effects:
- Common side effects: Fatigue, headache, nausea, and diarrhea.
- Serious side effects: Liver enzyme abnormalities, risk of hepatitis B reactivation in co-infected individuals, and allergic reactions.
Precautions:
- Hepatitis B screening: Before starting treatment, patients should be tested for hepatitis B infection.
- Pregnancy: Velpaclear should not be used during pregnancy unless the benefits outweigh the risks.
- Drug interactions: Velpaclear may interact with certain other medications, so it's important to discuss all medications with your healthcare provider.
Storage:
Store Velpaclear tablets at room temperature (20°C to 25°C). Keep the medication in its original packaging and protect from moisture.
Conclusion:
Velpaclear 400 mg/100 mg tablets are an effective treatment for chronic hepatitis C, improving viral suppression and reducing the likelihood of disease progression. Regular monitoring and follow-up are essential during treatment.
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Trustiva 300mg/600mg/200mg Tablet
Product Price: Rs 3,500 / BottleGet Best Price
Product Brochure
Product Details:
| Dose/Strength | 300 mg/600 mg/200 mg |
| Strength | 300 mg/600 mg/200 mg |
| Brand | Trustiva |
| Pack Size | 30 Capsules in 1 Bottle |
| Composition (salt) | Emtricitabine 200 mg + Tenofovir disoproxil fumarate 300 mg + Efavirenz 600 mg |
| Brand Name | Trustiva 300 mg/600 mg/200 mg Tablet |
| Manufactured | Hetero Drugs Ltd |
| Treatment | HIV infection |
Trustiva 300mg/600mg/200mg Tablet
Overview:
Trustiva is a combination antiretroviral medication containing 300 mg of Tenofovir disoproxil fumarate, 600 mg of Efavirenz, and 200 mg of Emtricitabine. It is used in the treatment of HIV-1 infection, either alone or in combination with other antiretroviral agents. This fixed-dose combination helps reduce the viral load, improves immune function, and prevents the progression of HIV to AIDS. It works by inhibiting different steps in the HIV replication cycle: Tenofovir and Emtricitabine are nucleotide reverse transcriptase inhibitors (NRTIs), while Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
Indications:
Trustiva 300mg/600mg/200mg Tablet is indicated for:
- HIV-1 Infection: For the treatment of HIV-1 in adults and children over 12 years of age.
- Combination Therapy: It is used in combination with other antiretrovirals as part of a multi-drug regimen for optimal viral suppression.
Mechanism of Action:
- Tenofovir: Blocks the HIV reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA.
- Emtricitabine: Similar to Tenofovir, it inhibits reverse transcriptase, preventing viral replication.
- Efavirenz: Non-competitively binds to reverse transcriptase, preventing it from synthesizing HIV DNA, thus halting viral replication.
Dosage and Administration:
- Recommended Dose: The usual adult dose is one tablet once daily, taken with or without food.
- Administration: Swallow the tablet whole with water.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it is almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Headache, nausea, dizziness, fatigue, and sleep disturbances.
Serious side effects may include: - Liver toxicity: Hepatitis or liver enzyme abnormalities.
- Psychiatric effects: Mood changes, depression, and suicidal thoughts, especially with Efavirenz.
- Rash: Severe rashes can develop, requiring immediate medical attention.
Precautions:
- Liver disease: Caution is required for patients with liver problems, and liver enzymes should be monitored regularly.
- Pregnancy: Efavirenz is contraindicated in pregnancy during the first trimester. The combination may still be used in later stages, but only under a doctor’s supervision.
Monitoring:
- Liver function: Regular liver tests are necessary.
- Renal function: Tenofovir can affect kidney function, so monitoring is required.
- Psychiatric effects: Regular mental health check-ups are important.
Storage:
Store Trustiva at room temperature (20°C to 25°C), away from moisture and heat. Keep the tablet in its original container and out of reach of children.
Conclusion:
Trustiva 300mg/600mg/200mg Tablet is an effective HIV treatment that combines three antiretroviral agents into one tablet. It helps reduce viral load, improve immune function, and prevent HIV progression. Patients should be monitored for potential side effects, particularly related to liver and mental health.
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Sofocure L 90 mg/400 mg Tablet
Product Price: Rs 6,350 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 90mg/400mg |
| Brand | Sofocure L |
| Pack Size | 10 Tablets in 1 Bottle |
| Dose | 90 mg/400 mg |
| Salt Composition | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Brand Name | Sofocure L tablet |
| Manufactured | Emcure Pharmaceuticals Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Sofocure L 90mg/400mg Tablet
Overview:
Sofocure L is a combination tablet that contains Ledipasvir 90mg and Sofosbuvir 400mg. It is used to treat chronic hepatitis C virus (HCV) infection in adults. The combination of these two antiviral agents works by inhibiting key enzymes necessary for the replication of the HCV virus, reducing the viral load and preventing liver damage. Sofocure L is typically used for HCV genotype 1 infections, with or without cirrhosis, and in certain cases, it may be combined with other antiviral agents for treating other genotypes.
Indications:
Sofocure L is primarily indicated for:
- Chronic Hepatitis C Virus (HCV): Treatment of HCV genotype 1 infection in adults, with or without cirrhosis.
- Co-infection with HIV: For patients with both HIV and chronic HCV infection.
- Other HCV Genotypes: In some cases, Sofocure L is used in combination with other drugs to treat non-genotype 1 infections.
Mechanism of Action:
- Ledipasvir is an NS5A inhibitor that blocks the replication and assembly of the HCV virus by binding to the NS5A protein, a key protein required for the virus to replicate.
- Sofosbuvir is an NS5B polymerase inhibitor that inhibits the NS5B RNA polymerase, which is crucial for viral RNA replication. By blocking these enzymes, Sofocure L prevents HCV replication, allowing the immune system to clear the virus.
Dosage and Administration:
- Recommended Dose: The usual dose is one tablet of Sofocure L once daily, taken with or without food.
- Administration: Swallow the tablet whole; do not crush, chew, or break it.
- Missed Dose: If a dose is missed, take it as soon as possible unless it’s almost time for the next dose. Do not double the dose to make up for a missed dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, diarrhea, and insomnia.
Serious side effects may include: - Hepatotoxicity: Monitor liver function regularly during treatment.
- Bradycardia: When used with certain other medications, it may cause slow heart rate.
- Rash and allergic reactions such as swelling or difficulty breathing.
Precautions:
- Pregnancy: Sofocure L is not recommended during pregnancy unless clearly needed.
- Drug Interactions: Consult a healthcare provider about any other medications being taken, as interactions can occur.
- Renal Impairment: Dose adjustments may be needed in patients with severe kidney problems.
Storage:
Store Sofocure L tablets at room temperature (20°C to 25°C), away from light and moisture. Keep the tablets in the original packaging, and out of reach of children.
Conclusion:
Sofocure L (Ledipasvir/Sofosbuvir) is an effective treatment for chronic hepatitis C infection. It works by blocking critical viral enzymes, helping reduce viral replication and improve liver health. Regular monitoring for side effects, especially liver function, is essential during treatment.
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Virso 400 mg Tablet
Product Price: Rs 3,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | Virso |
| Pack Size | 28 tablets |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg |
| Brand Name | Virso 400 mg |
| Manufactured | Strides Acrolab Limited |
| Usage/Application | Chronic hepatitis C virus (HCV) Infection |
Virso 400mg Tablet
Overview:
Virso 400mg Tablet contains Sofosbuvir 400mg, an antiviral medication used primarily to treat chronic hepatitis C virus (HCV) infection in adults. Sofosbuvir is a nucleoside analog inhibitor of the NS5B RNA polymerase, an enzyme essential for the replication of the HCV virus. By blocking this enzyme, Virso prevents the virus from replicating, reducing the viral load, and helping to prevent liver damage associated with chronic hepatitis C.
Indications:
Virso 400mg Tablet is indicated for:
- Chronic Hepatitis C: Treatment of HCV genotype 1, 2, 3, and 4 infections in adults.
- Co-infection with HIV: Used in combination with other antivirals in patients co-infected with HIV and HCV.
Mechanism of Action:
Sofosbuvir, the active ingredient in Virso, inhibits the NS5B RNA polymerase, a key enzyme involved in the replication of the hepatitis C virus. By blocking this enzyme, Sofosbuvir halts viral RNA synthesis, preventing further replication of the virus and allowing the immune system to control and clear the infection more effectively.
Dosage and Administration:
- Recommended Dose: The usual dose is one 400mg tablet once daily, with or without food.
- Administration: Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
- Missed Dose: If you miss a dose, take it as soon as possible, unless it’s close to your next dose. Do not take two doses at the same time.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, insomnia, and anemia.
Serious side effects may include: - Hepatotoxicity: Liver function should be monitored regularly.
- Bradycardia: Slower heart rate may occur when taken with certain medications.
- Allergic reactions: Rare, but may include rash, swelling, or difficulty breathing.
Precautions:
- Pregnancy: Virso is not recommended during pregnancy unless clearly needed.
- Drug Interactions: Inform your doctor of all medications you are currently taking, as interactions can occur.
- Renal Impairment: Patients with severe kidney dysfunction may require dose adjustments.
Storage:
Store Virso 400mg Tablet at room temperature (20°C to 25°C), away from light and moisture. Keep the tablet in its original packaging and out of reach of children.
Conclusion:
Virso 400mg Tablet is an effective antiviral treatment for chronic hepatitis C. By inhibiting the NS5B RNA polymerase, it prevents viral replication and aids in liver health. Regular monitoring for side effects and liver function is essential during treatment.
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Tenofovir Alafenamide Tablet (Tenohep AF 25 mg Tablet)
Product Price: Rs 1,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 25 mg |
| Usage | Hepatitis B |
| Dose Strength | 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Composition | Tenofovir Alafenamide 25 mg |
| Brand Name | Tenohep AF Tablet |
| Treatment | Chronic hepatitis B virus (HBV) infection |
| Manufacturer | Zydus Cadila |
Tenofovir Alafenamide Tablet
Overview: Tenofovir Alafenamide (TAF) is an antiretroviral medication used in the treatment of HIV-1 infection and chronic hepatitis B. It is a prodrug of tenofovir, designed to deliver higher concentrations of the active drug to target cells while minimizing the impact on kidney and bone health. TAF is a nucleoside reverse transcriptase inhibitor (NRTI), which works by blocking the reverse transcriptase enzyme, essential for the replication of HIV and hepatitis B viruses. TAF is typically used as part of a combination therapy.
Indications:
- HIV-1 infection: Used in combination with other antiretroviral agents to manage HIV-1 in adults and children (weighing at least 25 kg).
- Chronic Hepatitis B: For the treatment of chronic hepatitis B in adults with evidence of active viral replication.
Mechanism of Action: TAF is metabolized into the active compound tenofovir, which inhibits reverse transcriptase. This prevents the conversion of viral RNA into DNA, thus halting viral replication. Compared to its predecessor, Tenofovir Disoproxil Fumarate (TDF), TAF offers a more targeted approach, allowing lower doses and reducing potential side effects.
Dosage and Administration:
- Recommended Dose: The typical dose is 25 mg once daily.
- Administration: Take one tablet daily, with or without food. The tablet should not be chewed or crushed.
- Renal Adjustment: Caution is advised in patients with renal impairment; dose adjustments may be needed.
Side Effects:
- Common Side Effects: Nausea, headache, fatigue, diarrhea, and dizziness.
- Serious Side Effects: Kidney toxicity, bone mineral density loss, lactic acidosis, and liver toxicity.
Precautions:
- Renal Function: Regular monitoring of kidney function is recommended.
- Liver Disease: In patients with hepatitis B, liver enzymes should be monitored regularly.
- Pregnancy: Use during pregnancy only if clearly needed; consult a healthcare provider.
Storage: Store Tenofovir Alafenamide at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion: Tenofovir Alafenamide (TAF) is an effective and safer alternative to previous formulations of tenofovir. It is key in the management of HIV and hepatitis B, offering patients a more tolerable treatment option with regular monitoring for side effects.
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Tenolam Tenofovir Disoproxil Fumarate LamivudineTablets
Product Price: Rs 1,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Tenolam |
| Packaging Size | 1x30Tablets |
| Composition | Lamivudine 300 mg + Tenofovir Disoproxil Fumarate 300 mg |
| Brand Name | Tenolam Tablets |
| Manufacturers | Hetero Drugs Ltd |
| Treatment | HIV infection |
Tenolam Tenofovir Disoproxil Fumarate and Lamivudine Tablets
Overview:Tenolam combines Tenofovir Disoproxil Fumarate (300 mg) and Lamivudine (150 mg), two antiviral medications used to treat HIV-1 infection and chronic hepatitis B (HBV). Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI), and Lamivudine is also an NRTI. Together, they work by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of HIV and HBV. By blocking viral replication, Tenolam reduces the viral load, improves immune function in HIV patients, and helps manage chronic hepatitis B.
Indications:Tenolam Tablets are indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen for adults and children.
- Chronic Hepatitis B (HBV): For adults with chronic HBV infection who have evidence of active viral replication and liver damage.
Tenofovir Disoproxil Fumarate is converted into its active form, Tenofovir, in the body. Tenofovir inhibits the reverse transcriptase enzyme, preventing viral replication in both HIV and HBV. Lamivudine works similarly, also blocking reverse transcriptase. Together, these medications suppress viral replication, reduce the viral load, and help preserve liver function in HBV patients while improving immune function in HIV patients.
Dosage and Administration:- Recommended Dose: One Tenolam tablet (containing 300 mg Tenofovir and 150 mg Lamivudine) is taken once daily.
- Administration: The tablet should be swallowed whole with a glass of water. It can be taken with or without food. To maximize the medication's effectiveness, take it at the same time each day.
-
Common Side Effects:
- Nausea
- Fatigue
- Headache
- Diarrhea
- Dizziness
-
Serious Side Effects:
- Kidney toxicity (renal issues)
- Lactic acidosis (buildup of lactic acid in the body)
- Hepatomegaly (liver enlargement) and steatosis (fatty liver)
- Bone mineral density loss (osteomalacia)
Regular kidney and liver function tests are recommended during treatment.
Precautions:- Kidney Impairment: Use caution in patients with pre-existing kidney conditions. Renal function should be monitored during treatment.
- Liver Disease: Regular liver function monitoring is essential, especially for patients with chronic hepatitis B or other liver conditions.
- Pregnancy: Category C: There may be risks to the fetus, so consult your healthcare provider if pregnant or planning to become pregnant.
- Breastfeeding: Both Tenofovir and Lamivudine are excreted in breast milk. Consult your doctor before breastfeeding.
- Store Tenolam Tablets at room temperature (15°C to 30°C), away from light and moisture.
- Keep out of reach of children and store in the original packaging.
Tenolam Tenofovir Disoproxil Fumarate and Lamivudine Tablets offer a combination therapy for the treatment of HIV-1 infection and chronic hepatitis B. This dual-drug formulation helps manage viral replication, improve immune function in HIV, and protect liver health in HBV patients. Regular follow-up care, including monitoring of kidney and liver function, is crucial for safe and effective use.
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Revolade Eltrombopag 50 mg Tablet
Product Price: Rs 5,500 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 50 mg |
| Pack Size | 14 Tablets |
| Brand | Revolade 50 mg |
| Composition | Eltrombopag 50 mg |
| Packaging size | 14 Tablets in 1 Box |
| Manufactured By | GSK - Glaxo Smith Kline |
| Treatment | Low platelet count because of ITP or HCV contamination |
Revolade Eltrombopag 50 mg Tablet
Overview:
Revolade (Eltrombopag) is an oral medication used to treat thrombocytopenia (low platelet count) in various conditions, including chronic immune thrombocytopenia (ITP), severe aplastic anemia, and hepatitis C-associated thrombocytopenia. Eltrombopag is a thrombopoietin receptor agonist that stimulates the production of platelets by activating the thrombopoietin receptor (Mpl) on bone marrow cells. This leads to increased platelet production in the body.
Indications:
Revolade 50 mg is primarily indicated for:
- Chronic Immune Thrombocytopenia (ITP): In patients who have not responded to corticosteroids, immunoglobulins, or splenectomy.
- Severe Aplastic Anemia: In combination with standard immunosuppressive therapy.
- Hepatitis C: To treat thrombocytopenia associated with hepatitis C infection in patients undergoing antiviral therapy.
Mechanism of Action:
Eltrombopag works by binding to the thrombopoietin receptor (Mpl) on hematopoietic cells in the bone marrow, stimulating the production of platelets. This increases the platelet count, which helps to reduce the risk of bleeding in patients with low platelet levels.
Dosage and Administration:
- Recommended Dose: For ITP, the typical starting dose is 50 mg once daily. The dose may be adjusted based on platelet response.
- Administration: Take Revolade 50 mg tablet orally once a day, with or without food. Swallow the tablet whole. Do not crush or chew.
- Missed Dose: If a dose is missed, take it as soon as possible unless it's near the time for the next dose. Do not double doses.
Side Effects:
- Common Side Effects: Headache, fatigue, nausea, and diarrhea.
- Serious Side Effects: Liver enzyme abnormalities, thrombosis, and cataracts. Regular liver function monitoring is recommended.
Precautions:
- Liver Function: Eltrombopag can increase liver enzymes, so liver function should be closely monitored.
- Thrombosis: The risk of blood clots may be increased, especially when combined with other pro-thrombotic agents.
- Pregnancy: Revolade is not recommended during pregnancy unless the benefit outweighs the risk.
Storage:
Store Revolade 50 mg tablets at room temperature (15°C to 30°C), away from light and moisture.
Conclusion:
Revolade (Eltrombopag) is a valuable treatment for thrombocytopenia associated with conditions like ITP and severe aplastic anemia. Proper monitoring for side effects, especially liver function, is important for patient safety.
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Sofocure 400 mg Tablets
Product Price: Rs 3,200 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Pack Size | 28 tablets |
| Brand | Sofocure 400 mg |
| Manufacturer | Emcure Pharmaceuticals Ltd |
| Packaging Size | 28 Tablet |
| Composition | Sofosbuvir 400 mg |
| Treatment | Chronic Hepatitis C Virus (HCV) Infecti |
| Dose/Strength | 400 mg |
Sofocure 400 mg Tablets
Overview:Sofocure 400 mg Tablets contain Sofosbuvir, an antiviral medication used in the treatment of chronic hepatitis C (HCV) infection. Sofosbuvir is classified as a direct-acting antiviral (DAA) and is a nucleotide analog inhibitor that targets the NS5B RNA polymerase enzyme, which is essential for the replication of the hepatitis C virus. By inhibiting this enzyme, Sofosbuvir prevents the virus from replicating, reducing the viral load, and helping to achieve a sustained virologic response (SVR). SVR is a marker of viral clearance, which can result in the cure of the infection.
Indications:Sofocure 400 mg Tablets are primarily indicated for the treatment of:
- Chronic Hepatitis C (HCV) infection: Used in combination with other antiviral agents (e.g., Daclatasvir, Ledipasvir, or Ribavirin) based on the genotype of the virus and the patient's clinical condition. It is effective in treating genotypes 1, 2, 3, and 4 of HCV.
Sofosbuvir works by inhibiting the NS5B RNA polymerase enzyme that is responsible for replicating the hepatitis C virus. By preventing the replication of the viral genome, Sofosbuvir reduces the overall viral load in the bloodstream. This action helps improve liver function and, in many cases, can lead to the complete eradication of the virus, offering a potential cure for the patient.
Dosage and Administration:- Recommended Dose: The standard dose for Sofocure 400 mg is one tablet daily.
- Administration: Sofosbuvir should be taken orally with or without food. The tablet should be swallowed whole, and it should not be crushed or chewed. It is important to take Sofocure at the same time every day for consistent therapeutic effects.
- Common Side Effects: Fatigue, headache, nausea, insomnia, and anemia (when combined with Ribavirin).
- Serious Side Effects: Hepatitis B reactivation in co-infected patients, liver damage in advanced cirrhosis, and drug interactions with other antiviral agents. Regular liver and kidney function monitoring is recommended.
- Kidney Impairment: Caution is advised for those with severe renal impairment or end-stage renal disease (ESRD).
- Pregnancy: Sofosbuvir is often used with Ribavirin, which is contraindicated during pregnancy due to teratogenic risks. Women of childbearing age should use effective contraception.
- Breastfeeding: Consult a healthcare provider before breastfeeding during treatment.
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Sofocure 400 mg Tablets are an effective treatment for chronic hepatitis C infection. When combined with other antiviral medications, Sofosbuvir helps clear the virus from the body and improve liver health. Regular medical monitoring is essential to ensure safe and effective treatment.
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Tafnat Tenofovir Alafenamide 25 mg Tablets
Product Price: Rs 2,500 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 25 mg |
| Usage | Hepatitis B |
| Dose Strength | 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Composition | Tenofovir Alafenamide 25 mg |
| Brand Name | Tfnat 25 mg |
| Treatment | Chronic hepatitis B |
| Manufacturer | Natco Pharma Ltd |
Tafnat Tenofovir Alafenamide 25 mg Tablets
Overview:Tafnat 25 mg Tablets contain Tenofovir Alafenamide (TAF), a nucleotide reverse transcriptase inhibitor (NRTI) used to treat HIV-1 infection and chronic hepatitis B (HBV). TAF is a prodrug of Tenofovir, which is selectively activated in the body to deliver the active metabolite, Tenofovir, directly to the cells where it inhibits the reverse transcriptase enzyme. This enzyme is essential for the replication of both HIV and HBV. By blocking this enzyme, TAF helps reduce viral replication, lower viral load, and improve immune function in HIV patients, while also controlling HBV replication.
Indications:Tafnat 25 mg Tablets are indicated for:
- HIV-1 Infection: In combination with other antiretroviral agents as part of a combination antiretroviral therapy (ART) regimen in adults and children.
- Chronic Hepatitis B (HBV): For the treatment of chronic HBV infection in adults with evidence of active viral replication and liver damage.
Tenofovir Alafenamide (TAF) is a prodrug of Tenofovir, meaning it is converted to its active form, Tenofovir, after entering cells. Tenofovir inhibits the reverse transcriptase enzyme, which HIV and HBV use to replicate their genetic material. By blocking reverse transcriptase, TAF reduces viral replication, lowers the viral load, and improves immune function in HIV patients, while preventing further liver damage in HBV patients.
Dosage and Administration:- Recommended Dose: One Tafnat 25 mg tablet is taken once daily, usually in combination with other HIV or HBV medications.
- Administration: Take the tablet with or without food. Swallow the tablet whole with a glass of water. It is important to take the medication at the same time each day for the best effect.
- Common Side Effects: Nausea, headache, fatigue, and diarrhea.
- Serious Side Effects: Kidney toxicity, liver problems (e.g., lactic acidosis, hepatomegaly), and bone mineral density loss (osteomalacia). Monitoring kidney and liver function is advised during treatment.
- Kidney Impairment: Use with caution in patients with pre-existing kidney disease. Regular monitoring of renal function is recommended.
- Liver Disease: In patients with HBV, liver function should be monitored regularly, especially after discontinuing treatment.
- Pregnancy and Lactation: Consult a healthcare provider before use during pregnancy or breastfeeding.
Store Tafnat 25 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Tafnat Tenofovir Alafenamide 25 mg Tablets are an effective treatment for HIV-1 infection and chronic hepatitis B. When taken as prescribed, it helps reduce viral load, improves immune function, and prevents liver damage in HBV patients. Regular medical follow-ups are necessary to monitor potential side effects, particularly kidney and liver function.
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Ricovir Tenofovir 300 mg Tablets
Product Price: Rs 1,500 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Ricovir |
| Packaging Size | 1x30Tablets |
| Composition | Tenofovir Disoproxil Fumarate 300 mg |
| Brand Name | Ricovir 300 mg |
| Manufacturers | Mylan Pharmaceuticals Pvt Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Ricovir Tenofovir 300 mg Tablets
Overview:
Ricovir Tenofovir 300 mg Tablets contain Tenofovir Disoproxil Fumarate, a nucleotide reverse transcriptase inhibitor (NRTI), used to treat HIV-1 infection and chronic hepatitis B virus (HBV) infection. Tenofovir works by inhibiting the action of reverse transcriptase, an enzyme necessary for the replication of the HIV and HBV viruses. By stopping the virus from replicating, Ricovir helps reduce the viral load in the body, preventing further damage to the immune system.
Indications:
Ricovir is indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen for adults and children over 2 years old.
- Chronic Hepatitis B: In adults with compensated liver disease.
Mechanism of Action:
- Tenofovir: Inhibits the reverse transcriptase enzyme in the HIV or HBV virus, preventing viral replication. It is converted into the active metabolite tenofovir diphosphate inside cells, which directly interferes with viral RNA and DNA synthesis.
Dosage and Administration:
- Recommended Dose: One tablet (300 mg) taken orally once a day with or without food.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it’s almost time for the next dose. Do not double the dose.
Side Effects:
Common side effects of Ricovir may include:
- Diarrhea, headache, dizziness, and nausea.
- Serious side effects may include:
- Renal dysfunction: Kidney problems may occur, especially in patients with pre-existing kidney disease.
- Liver issues: Hepatitis or worsening of HBV infection if treatment is stopped suddenly.
- Bone mineral density loss: Long-term use may lead to bone thinning and fractures.
Precautions:
- Renal Impairment: Regular monitoring of kidney function is essential.
- Hepatic Impairment: Caution is required in patients with liver disease, especially hepatitis B.
- Pregnancy and Breastfeeding: Consult your healthcare provider. Ricovir is not recommended during pregnancy unless absolutely necessary.
Monitoring:
- Kidney Function: Serum creatinine and eGFR should be monitored regularly.
- Liver Function: Liver enzymes (ALT, AST) should be tested before and during treatment.
Storage:
Store Ricovir Tenofovir tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of the reach of children.
Conclusion:
Ricovir Tenofovir 300 mg Tablets are a key part of combination therapy for managing HIV-1 and chronic hepatitis B, reducing viral load and improving immune function. Regular monitoring for side effects, particularly kidney and liver function, is essential to ensure safe and effective treatment.
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Tenohep 300 Mg Tablet
Product Price: Rs 150 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Tenohep |
| Packaging Size | 1x10Tablets |
| Composition | Tenofovir Disoproxil Fumarate |
| Brand Name | Tenohep 300 mg |
| Manufacturers | Zydus Cadila |
| Treatment | HIV infections, Chronic hepatitis. |
Tenohep 300 mg Tablet
Overview: Tenohep (Tenofovir Disoproxil Fumarate 300 mg Tablet) is an antiretroviral medication used to treat chronic hepatitis B and HIV infection. It is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of the HIV and hepatitis B viruses. By blocking this enzyme, Tenohep helps to prevent the virus from multiplying, improving liver function and reducing viral load.
Indications: Tenohep 300 mg Tablet is primarily indicated for:
- Chronic Hepatitis B (HBV): To treat chronic hepatitis B infection in adults.
- HIV-1 Infection: Used in combination with other antiretroviral agents for the treatment of HIV-1 infection.
Mechanism of Action: The active ingredient, Tenofovir Disoproxil Fumarate, is converted into Tenofovir inside the body. Tenofovir works by:
- Inhibiting reverse transcriptase, an enzyme that the hepatitis B virus and HIV need to replicate their genetic material.
- Reducing the viral load in the bloodstream, which can help improve liver function in hepatitis B patients and reduce the progression of HIV.
Dosage and Administration:
- Recommended Dose: 1 tablet (300 mg) once daily for adults, with or without food.
- Administration: Swallow the tablet whole with a full glass of water. It is recommended to take it at the same time each day.
Side Effects:
- Common Side Effects: Nausea, headache, fatigue, and diarrhea.
- Serious Side Effects: Kidney problems, liver issues, bone loss, lactic acidosis (a rare but serious condition), and pancreatitis.
Precautions:
- Renal Impairment: Regular kidney function tests are recommended during treatment.
- Pregnancy: Consult a doctor before using during pregnancy.
- Bone Health: Regular bone density monitoring may be necessary.
Storage: Store Tenohep 300 mg Tablet at room temperature (15°C to 30°C) in a dry place, away from light and moisture.
Conclusion: Tenohep 300 mg Tablet is a valuable medication in managing chronic hepatitis B and HIV infection. It helps control viral replication and improve quality of life. Monitoring kidney function and bone health is essential during treatment.
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Tenvir Tenofovir 300 mg Tablets
Product Price: Rs 1,200 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Tenvir |
| Packaging Size | 1x30Tablets |
| Composition | Tenofovir Disoproxil 300 mg |
| Brand Name | Tenvir 300 mg |
| Manufactured | Cipla Ltd |
| Treatment | HIV, Chronic hepatitis B. |
Tenvir Tenofovir 300mg Tablets
Overview: Tenvir is a medication that contains Tenofovir Disoproxil Fumarate (300 mg), an antiretroviral drug used to treat HIV-1 infection and chronic hepatitis B (HBV). Tenofovir is a nucleoside reverse transcriptase inhibitor (NRTI) that works by inhibiting the reverse transcriptase enzyme, which is necessary for the HIV virus to replicate. By blocking this enzyme, Tenvir helps reduce the viral load and improves immune function in patients with HIV or HBV.
Indications: Tenvir 300 mg Tablet is indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen in adults and children.
- Chronic Hepatitis B (HBV): For adults with HBV infection who have evidence of active viral replication and liver damage.
Mechanism of Action: Tenofovir works by inhibiting reverse transcriptase, an enzyme used by HIV and HBV to replicate their genetic material. By blocking this enzyme, Tenofovir prevents the virus from multiplying, reducing viral load, and slowing the progression of HIV or HBV infection.
Dosage and Administration:
- Recommended Dose: One Tenvir 300 mg tablet once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It is important to take Tenvir regularly at the same time each day to maximize its effectiveness.
Side Effects:
- Common Side Effects: Headache, fatigue, nausea, diarrhea, and dizziness.
- Serious Side Effects: Lactic acidosis, liver problems, kidney toxicity, and bone mineral density loss. Regular monitoring of kidney function and liver enzymes is recommended.
Precautions:
- Kidney Impairment: Use with caution in patients with pre-existing kidney disease.
- Liver Disease: Regular monitoring is required for patients with hepatitis or liver problems.
- Pregnancy: Consult a healthcare provider if pregnant or planning to become pregnant.
Storage: Store Tenvir 300 mg tablets at room temperature (15°C to 30°C), away from light and moisture.
Conclusion: Tenvir Tenofovir 300 mg Tablet is an effective treatment for HIV and chronic hepatitis B. It should be taken as prescribed to ensure optimal viral suppression and reduce the risk of resistance. Regular medical check-ups are necessary for monitoring side effects.
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Tenofovir Disoproxil Fumarate Tablets (Teravir 300 mg Tablet)
Product Price: Rs 700 / BottleGet Best Price
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Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Teravir |
| Packaging Size | 1x30Tablets |
| Composition | Tenofovir disoproxil fumarate 300 mg |
| Brand Name | Teravir 300 mg Table |
| Manufacturers | Cipla Ltd |
| Treatment | Chronic hepatitis B virus (HBV) infection |
Tenofovir Disoproxil Fumarate Tablets (Teravir)
Overview: Tenofovir Disoproxil Fumarate (Teravir) is an antiretroviral medication used for the treatment of HIV-1 infection and chronic hepatitis B. It is classified as a nucleoside reverse transcriptase inhibitor (NRTI). Teravir works by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of HIV and hepatitis B virus. By blocking this enzyme, it reduces viral replication, helping to control the spread of the virus in the body. Teravir is commonly used in combination with other antiretroviral agents.
Indications:
- HIV-1 infection: Teravir is used as part of a combination therapy for HIV in adults and children over 35 kg.
- Chronic Hepatitis B: Teravir is used for the treatment of chronic hepatitis B in adults with evidence of active viral replication.
Mechanism of Action: Tenofovir Disoproxil Fumarate is metabolized into the active compound Tenofovir in the body. As an NRTI, it inhibits reverse transcriptase, preventing viral RNA from being converted into DNA. This stops the replication of HIV and hepatitis B viruses, reducing the viral load and improving clinical outcomes.
Dosage and Administration:
- Recommended Dose: 300 mg once daily.
- Administration: Take one tablet daily, with or without food. Do not chew or crush the tablet.
- Renal Adjustment: Use with caution in patients with renal impairment; dosage adjustments may be needed.
Side Effects:
- Common Side Effects: Nausea, fatigue, headache, diarrhea, and dizziness.
- Serious Side Effects: Renal toxicity, lactic acidosis, liver damage, and decreased bone mineral density.
Precautions:
- Renal Impairment: Monitor renal function regularly.
- Liver Disease: Monitor liver enzymes in patients with chronic hepatitis B or liver cirrhosis.
- Pregnancy: Use Teravir only if necessary during pregnancy, as it is secreted in breast milk.
Storage: Store Teravir at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion: Teravir (Tenofovir Disoproxil Fumarate) is an essential treatment for managing HIV and hepatitis B. Adherence to the prescribed regimen and regular monitoring for side effects ensure optimal therapeutic outcomes.
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Tenofovir Disoproxil Fumarate Tablets (Tenof 300 mg Tablet)
Product Price: Rs 1,500 / BottleGet Best Price
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Product Details:
| Strength | 300 mg |
| Dose/Strength | 300 mg |
| Pack Size | 30 tablets |
| Brand | Tenof |
| Usage | Chronic Hepatitis B |
| Packaging Size | 1x30Tablets |
| Composition | Tenofovir Disoproxil Fumarate 300 mg |
| Brand Name | Tenof |
| Manufacturers | Hetero Drugs Ltd |
| Treatment | HIV infections, Chronic hepatitis. |
Tenofovir Disoproxil Fumarate Tablets (Tenof)
Overview:Tenofovir Disoproxil Fumarate (brand name Tenof) is an antiviral medication primarily used to treat HIV-1 infection and chronic hepatitis B (HBV). It belongs to the class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). Tenofovir works by inhibiting the reverse transcriptase enzyme, which is essential for the replication of both HIV and HBV. By blocking this enzyme, Tenof reduces viral replication, lowers viral load, and helps protect the immune system in HIV patients, while also improving liver function in those with HBV.
Indications:Tenofovir Disoproxil Fumarate (Tenof) is indicated for:
- HIV-1 Infection: As part of a combination antiretroviral therapy (ART) regimen for adults and children.
- Chronic Hepatitis B (HBV): For adults with chronic HBV infection showing active viral replication and evidence of liver damage.
Tenofovir is converted to its active form, Tenofovir, once in the body. Tenofovir inhibits reverse transcriptase, an enzyme HIV and HBV use to replicate their viral genomes. By blocking this enzyme, Tenof prevents the viruses from multiplying, reducing viral load, and helping to improve immune function in HIV patients and liver health in those with HBV.
Dosage and Administration:- Recommended Dose: One 300 mg tablet of Tenofovir Disoproxil Fumarate is typically taken once daily.
- Administration: The tablet can be taken with or without food. It should be swallowed whole with a glass of water. It is important to take Tenof at the same time each day for consistent drug levels in the body.
-
Common Side Effects:
- Nausea
- Fatigue
- Headache
- Diarrhea
- Dizziness
-
Serious Side Effects:
- Kidney toxicity (renal issues)
- Lactic acidosis (a rare but serious condition involving buildup of lactic acid)
- Hepatomegaly (enlarged liver) and steatosis (fatty liver)
- Bone mineral density loss (osteomalacia)
Regular monitoring of kidney and liver function is recommended during treatment.
Precautions:- Kidney Impairment: Tenof should be used cautiously in patients with pre-existing kidney disease. Kidney function should be regularly monitored (e.g., serum creatinine, eGFR).
- Liver Disease: In patients with chronic HBV or other liver issues, liver function should be monitored closely.
- Pregnancy: Category B: No known harm in animal studies, but always consult your doctor if you are pregnant or planning to become pregnant.
- Breastfeeding: Tenofovir is excreted in breast milk. Discuss with your healthcare provider whether breastfeeding is advisable.
- Store Tenof tablets at room temperature (15°C to 30°C), away from moisture and light.
- Keep out of reach of children and store in the original packaging.
Tenofovir Disoproxil Fumarate (Tenof) is an effective treatment for HIV and chronic hepatitis B. It reduces viral load, improves immune function, and helps prevent the progression of liver disease in HBV patients. Adherence to the prescribed dosage and regular monitoring of kidney and liver function are crucial for ensuring the best outcomes during treatment.
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Viroclear Sofosbuvir 400mg Tablets
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | Viroclear |
| Pack Size | 28 tablets |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg |
| Brand Name | Viroclear 400 mg |
| Manufacturers | Abbott |
| Usage/Application | Chronic hepatitis C virus (HCV) Infection |
Viroclear Sofosbuvir 400mg Tablets
Overview: Viroclear contains Sofosbuvir, a direct-acting antiviral (DAA) used for the treatment of chronic hepatitis C (HCV). Sofosbuvir targets and inhibits the NS5B RNA-dependent RNA polymerase enzyme, which is essential for the replication of the hepatitis C virus. By blocking this enzyme, Sofosbuvir helps to reduce the viral load in the body and prevents the virus from replicating, leading to improved liver function and viral clearance in patients with HCV infection.
Indications: Viroclear 400mg is used to treat hepatitis C virus infection in adults, either as part of a combination therapy with other antivirals (such as Ledipasvir, Ribavirin, or Peginterferon) or as a stand-alone therapy. It is effective against HCV genotypes 1-6 and is recommended for both naive and treatment-experienced patients.
Mechanism of Action: Sofosbuvir inhibits the NS5B polymerase, which is responsible for replicating the HCV genome. By blocking this enzyme, Sofosbuvir prevents the virus from multiplying and thus reduces the viral load in the body, helping to restore liver function and promote viral clearance.
Dosage and Administration:
- Recommended dose: One 400mg tablet once daily.
- Administration: Can be taken with or without food. Swallow the tablet whole with water.
- Missed dose: If a dose is missed, take it as soon as you remember unless it is almost time for the next dose.
Side Effects:
- Common side effects: Fatigue, headache, nausea, and insomnia.
- Serious side effects: Liver issues (e.g., jaundice, dark urine), allergic reactions (skin rash, itching), and depression. Contact your healthcare provider if these occur.
Precautions:
- Liver disease: Regular liver function monitoring is advised, especially for patients with cirrhosis.
- Pregnancy and breastfeeding: Consult with a healthcare provider before using Sofosbuvir during pregnancy or breastfeeding.
- Drug interactions: Sofosbuvir may interact with other medications. Always inform your doctor of any concurrent treatments.
Storage: Store at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion: Viroclear Sofosbuvir 400mg is an effective antiviral treatment for hepatitis C. When used appropriately, it can significantly improve outcomes in patients with chronic HCV infection, helping to reduce viral load and enhance liver health.
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Hepbest Tenofovir Alafenamide 25 mg Tablets
Product Price: Rs 1,000 / BottleGet Best Price
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Product Details:
| Strength | 25 mg |
| Usage | Hepatitis B |
| Dose Strength | 25 mg |
| Packaging Size | 30 Tablets in 1 Bottle |
| Composition | Tenofovir Alafenamide 25 mg |
| Brand Name | Hepbest 25 mg |
| Treatment | Chronic Hepatitis B |
| Manufacturer | Mylan Pharmaceuticals Pvt Ltd |
Hepbest Tenofovir Alafenamide 25mg Tablets
Overview: Hepbest (Tenofovir Alafenamide) is an antiviral medication used in the treatment of chronic hepatitis B (HBV) infection in adults and pediatric patients over 12 years old. It is a nucleotide reverse transcriptase inhibitor (NRTI) that works by inhibiting the HBV virus’s reverse transcriptase enzyme, thus preventing the replication of the virus in the liver. By blocking the virus’s ability to reproduce, Hepbest reduces viral load, improves liver function, and reduces the risk of liver damage.
Indications: Hepbest 25mg Tablets are indicated for:
- Chronic Hepatitis B (HBV): Treatment of chronic HBV infection in adults and pediatric patients (aged 12 and older), to reduce viral load and prevent liver damage.
- Prevention of Liver Damage: It is used to prevent complications like cirrhosis, liver failure, and liver cancer in patients with chronic HBV.
Mechanism of Action: Tenofovir Alafenamide is a prodrug of Tenofovir, which gets converted into the active form in the bloodstream. It works by inhibiting the reverse transcriptase enzyme in the hepatitis B virus, which is essential for viral replication. This prevents the virus from multiplying and reduces its presence in the liver.
Dosage and Administration:
- Recommended Dose: The usual dose is 25 mg once daily.
- Administration: Take Hepbest tablets orally with or without food.
- Missed Dose: If a dose is missed, it should be taken as soon as possible, unless it is close to the time for the next dose.
Side Effects:
- Common side effects: Headache, fatigue, and nausea.
- Serious side effects: Kidney problems, bone density loss, and lactic acidosis (rare but serious).
Precautions:
- Kidney function: Monitor kidney function during treatment.
- Bone health: Periodic monitoring of bone density is advised, especially for long-term use.
- Pregnancy and breastfeeding: Hepbest should be used with caution in pregnant or breastfeeding women.
Storage: Store Hepbest 25mg Tablets at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion: Hepbest (Tenofovir Alafenamide 25mg) is a safe and effective treatment for chronic hepatitis B infection, offering improved safety profiles over older tenofovir formulations. Regular monitoring for kidney and bone health is essential during long-term use.
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Velpanat Sofosbuvir 400 mg Velpatasvir 100 mg
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Strength | 400 mg+ 100 mg |
| Pack Size | 28 tablets |
| Brand | Velpanat 400 mg |
| Manufacturer | Natco Pharma Ltd |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Velpanat (Sofosbuvir 400 mg + Velpatasvir 100 mg)
Overview:
Velpanat is a combination tablet containing Sofosbuvir (400 mg) and Velpatasvir (100 mg). This medication is used to treat chronic hepatitis C (HCV) infection. Sofosbuvir is an NS5B polymerase inhibitor, while Velpatasvir is an NS5A inhibitor. Together, they work to inhibit the replication of the hepatitis C virus, effectively lowering the viral load and improving liver function in infected individuals.
Indications:
Velpanat is indicated for the treatment of chronic hepatitis C infection in adult patients with genotype 1, 2, 3, 4, 5, or 6 of HCV. It is used in both treatment-naive and treatment-experienced patients, and those with or without cirrhosis.
Mechanism of Action:
- Sofosbuvir: Inhibits the NS5B RNA-dependent RNA polymerase, preventing viral RNA replication.
- Velpatasvir: Inhibits the NS5A protein, which is essential for viral replication and assembly.
By inhibiting both the NS5B polymerase and NS5A proteins, Velpanat blocks critical steps in the HCV lifecycle, preventing the virus from multiplying and spreading.
Dosage and Administration:
- Recommended Dose: One tablet of Velpanat (Sofosbuvir 400 mg / Velpatasvir 100 mg) is taken once daily with or without food.
- Treatment Duration: Typically 12 weeks; however, treatment may vary based on the patient's HCV genotype, prior treatments, and liver condition.
Side Effects:
- Common: Fatigue, headache, nausea, and anemia.
- Serious: Risk of hepatitis B reactivation in co-infected patients, liver issues, and allergic reactions.
Precautions:
- Hepatitis B: Before starting treatment, test for hepatitis B virus (HBV) infection, as HBV can reactivate during HCV treatment.
- Renal Impairment: Caution in patients with severe kidney impairment.
Storage:
Store Velpanat at room temperature (15°C to 30°C), away from light and moisture. Keep out of the reach of children.
Conclusion:
Velpanat is a highly effective and convenient treatment for HCV, combining two antiviral agents that target different steps in the viral replication process. It provides a safe and effective option for patients with chronic hepatitis C.
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Elromo Eltrombopag 50 mg Tablet
Product Price: Rs 1,200 / BoxGet Best Price
Minimum Order Quantity: 100 Box
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Product Details:
| Strength | 50 mg |
| Brand | Elromo |
| Pack Size | 28 Tablets |
| Composition | Eltrombopag |
| Packaging size | 4x7 |
| Brand Name | Elromo |
| Packaging Type | Box |
| Manufacturer | Zydus |
Elromo Eltrombopag 50mg Tablet
Overview:
Elromo (Eltrombopag) 50mg is an oral medication used to treat chronic immune thrombocytopenia (ITP), a condition where the body’s immune system destroys platelets, leading to an increased risk of bleeding. It is also used for severe aplastic anemia and chronic hepatitis C to increase platelet counts in patients receiving interferon-based therapies. Eltrombopag is a thrombopoietin receptor agonist that stimulates the production of platelets by the bone marrow, improving platelet count and reducing bleeding risks.
Indications:
Elromo 50mg is indicated for:
- Chronic Immune Thrombocytopenia (ITP): To increase platelet counts in patients with ITP who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy.
- Severe Aplastic Anemia: In combination with standard immunosuppressive therapy.
- Chronic Hepatitis C: To increase platelet counts in patients undergoing interferon-based therapy.
Mechanism of Action:
Eltrombopag works by binding to and activating the thrombopoietin receptor (TPO receptor) on the surface of cells in the bone marrow. This activation stimulates megakaryocyte (platelet-producing cells) proliferation and differentiation, leading to increased platelet production. As a result, Eltrombopag increases platelet counts and helps reduce bleeding risks in conditions like ITP and severe aplastic anemia.
Dosage and Administration:
- Recommended Dose: The typical starting dose is 50 mg once daily for adults. Doses may be adjusted based on platelet response.
- Administration: Elromo 50mg tablet should be taken orally, with or without food. Swallow the tablet whole; do not crush or chew.
- Missed Dose: If a dose is missed, take it as soon as you remember, but skip it if it’s near the time for the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Headache, nausea, fatigue, and upper respiratory tract infections.
Serious side effects may include: - Hepatotoxicity: Liver function tests should be monitored regularly.
- Bone Marrow Suppression: May cause low white blood cell or red blood cell counts, increasing the risk of infections and anemia.
- Thromboembolism: Increased risk of clot formation.
Precautions:
- Liver Disease: Monitor liver enzymes regularly due to the potential risk of hepatotoxicity.
- Pregnancy: Not recommended during pregnancy due to potential harm to the fetus.
- Blood Counts: Regular monitoring of blood counts is essential to ensure safety and assess the response to treatment.
Storage:
Store Elromo 50mg tablets at room temperature (20°C to 25°C), away from light and moisture, and out of the reach of children.
Conclusion:
Elromo (Eltrombopag) 50mg tablet is an effective treatment for increasing platelet counts in patients with chronic ITP, severe aplastic anemia, and chronic hepatitis C. Regular monitoring for side effects, especially liver function and blood counts, is essential for ensuring the safe and effective use of this medication.
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Virvel 400 Mg100mg Tablets
Product Price: Rs 7,500 / BoxGet Best Price
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Product Details:
| Strength | 500 mg |
| Dose/Strength | 400 mg |
| Brand | Virvel |
| Pack Size | 28 tablets |
| Composition | Sofosbuvir Velpatasvir |
| Prescription/Non prescription | Prescription |
| Form | Tablet |
| Brand Name | Virvel |
Virvel 400 mg/100 mg Tablets
Overview:
Virvel 400 mg/100 mg Tablets combine Sofosbuvir and Velpatasvir, two antiviral medications used together to treat chronic hepatitis C (HCV) infection. Sofosbuvir is a nucleoside analog, while Velpatasvir is an NS5A inhibitor. The combination works by targeting different steps in the replication cycle of the hepatitis C virus, effectively preventing the virus from multiplying and spreading throughout the body.
Indications:
Virvel 400 mg/100 mg Tablets are indicated for the treatment of chronic hepatitis C virus (HCV) infection in adults with genotypes 1, 2, 3, 4, 5, or 6. The combination is also used in patients with or without cirrhosis and for those who are coinfected with HIV.
Mechanism of Action:
- Sofosbuvir: Sofosbuvir is a nucleoside analog that inhibits the viral RNA polymerase enzyme (NS5B), preventing the replication of the hepatitis C virus.
- Velpatasvir: Velpatasvir inhibits the NS5A protein, which is crucial for the virus's replication and assembly. By targeting both the viral polymerase and the NS5A protein, this combination treatment inhibits viral replication at two different stages of the HCV life cycle.
Dosage and Administration:
- The recommended dose of Virvel 400 mg/100 mg Tablets is one tablet (400 mg of Sofosbuvir and 100 mg of Velpatasvir) once daily with or without food.
- The duration of treatment typically ranges from 12 weeks to 24 weeks, depending on the patient’s genotype, cirrhosis status, and previous treatments.
Side Effects:
Common side effects of Virvel 400 mg/100 mg Tablets include:
- Fatigue, headache, nausea, and insomnia.
Serious side effects are rare but may include: - Hepatitis B reactivation: In patients who are co-infected with hepatitis B, the use of this medication could lead to the reactivation of the virus.
- Liver function abnormalities: Close monitoring of liver function is required during treatment, especially in patients with pre-existing liver conditions.
Precautions:
- Hepatitis B Infection: Before starting treatment with Virvel, patients should be tested for hepatitis B, as reactivation of hepatitis B can occur in coinfected individuals.
- Drug Interactions: Virvel can interact with certain medications, including rifampin, St. John’s Wort, and some anticonvulsants. It is important to inform your healthcare provider of all other medications you are taking.
- Pregnancy and Breastfeeding: Virvel is classified as Category C for pregnancy. The safety of Sofosbuvir and Velpatasvir during pregnancy has not been well-studied, so it should only be used when the benefits outweigh the risks. It is unknown whether the drugs are excreted in breast milk.
Storage:
Store Virvel 400 mg/100 mg Tablets at room temperature (between 15°C and 30°C), away from moisture and light. Keep out of the reach of children.
Conclusion:
Virvel 400 mg/100 mg Tablets provide an effective treatment option for chronic hepatitis C infection. The combination of Sofosbuvir and Velpatasvir offers a potent, once-daily regimen that targets key stages of the HCV life cycle, helping to eliminate the virus and prevent complications like cirrhosis or liver failure. Close monitoring for side effects and drug interactions is recommended for optimal treatment outcomes.
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Tenvir L Tablets
Product Price: Rs 1,250 / BoxGet Best Price
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Product Details:
| Strength | 25 mg |
| Variant | Tenvir L |
| Packaging Type | Box |
| Brand | Tenvir L |
| Manufacured By | Cipla |
| Pack Size | 30 Tablet |
Tenvir L Tablets
Overview:
Tenvir L Tablets contain two active ingredients: Lamivudine (150mg) and Tenofovir Disoproxil Fumarate (300mg). These are used for the treatment of HIV/AIDS and chronic hepatitis B (HBV). Lamivudine and Tenofovir are both nucleoside reverse transcriptase inhibitors (NRTIs) that work by inhibiting the replication of HIV and HBV, helping to control viral load and slow disease progression.
Indications:
- HIV/AIDS: Tenvir L is used as part of combination antiretroviral therapy (ART) in HIV-infected adults and children aged 2 years and older.
- Chronic Hepatitis B: It is also indicated for the treatment of HBV in adults with evidence of active viral replication.
Mechanism of Action:
- Lamivudine and Tenofovir are converted into their active forms (lamivudine triphosphate and tenofovir diphosphate) inside the infected cells. These active forms inhibit the reverse transcriptase enzyme, stopping the conversion of viral RNA into DNA. This halts viral replication in HIV and HBV.
Dosage and Administration:
- HIV Treatment: One tablet (150mg Lamivudine/300mg Tenofovir) once daily, typically in combination with other antiretroviral drugs.
- HBV Treatment: One tablet once daily, as directed by your healthcare provider.
- Administration: Swallow the tablet whole with or without food. Take at the same time each day.
- Missed Dose: If you miss a dose, take it as soon as you remember, unless it's close to the next dose.
Side Effects:
- Common: Fatigue, headache, nausea, diarrhea, dizziness.
- Serious: Lactic acidosis, liver problems, kidney damage, bone loss, pancreatitis.
Precautions:
- Renal Impairment: Monitor kidney function, especially in those with pre-existing kidney disease.
- Liver Impairment: Regular monitoring of liver function is recommended.
- Pregnancy: Consult a healthcare provider before use during pregnancy.
Storage:
Store at room temperature (15°C to 30°C), away from heat and moisture. Keep out of reach of children.
Conclusion:
Tenvir L Tablets are an effective treatment for managing HIV and HBV, improving quality of life, and slowing the progression of these viral infections when used as part of a comprehensive treatment regimen.
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Tenvir EM Tablet
Product Price: Rs 1,500 / BoxGet Best Price
Minimum Order Quantity: 100 Box
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Product Details:
| Strength | 25 mg |
| Variant | Tenvir EM |
| Packaging Type | Box |
| Brand | Tenvir EM |
| Manufacured By | Cipla |
| Pack Size | 30 Tablets |
Tenvir EM Tablet (Tenofovir Disoproxil Fumarate / Emtricitabine)
Overview:
Tenvir EM is a combination tablet containing Tenofovir Disoproxil Fumarate (TDF) 300 mg and Emtricitabine (FTC) 200 mg, both of which are antiretroviral medications. This medication is primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children. Tenvir EM is also used in pre-exposure prophylaxis (PrEP) to reduce the risk of HIV infection in high-risk individuals. By inhibiting the reverse transcriptase enzyme, it helps to prevent the replication of the virus in the body.
Indications:
- HIV Infection: Tenvir EM is used as part of a combination antiretroviral therapy (ART) regimen for the treatment of HIV-1 infection.
- Pre-exposure Prophylaxis (PrEP): It is used to reduce the risk of HIV infection in individuals at high risk of contracting the virus.
Mechanism of Action:
- Tenofovir Disoproxil Fumarate (TDF): A nucleotide reverse transcriptase inhibitor (NRTI) that blocks the activity of reverse transcriptase, an enzyme the HIV virus needs to replicate.
- Emtricitabine (FTC): A nucleoside reverse transcriptase inhibitor (NRTI) that also inhibits reverse transcriptase to stop the replication of HIV.
By inhibiting this enzyme, both drugs prevent the virus from multiplying, reducing viral load in the blood and increasing the CD4+ cell count.
Dosage and Administration:
- Recommended dose: The usual dose for adults and adolescents is one Tenvir EM tablet (300 mg TDF + 200 mg FTC) once daily with or without food.
- Renal Impairment: Dose adjustments may be required in patients with renal dysfunction.
- Missed dose: If a dose is missed, it should be taken as soon as remembered, unless it is near the time for the next dose. Do not take two doses at the same time.
Side Effects:
Common side effects include:
- Nausea
- Diarrhea
- Fatigue
- Headache
- Insomnia
Serious side effects include:
- Kidney problems: Tenvir EM can affect kidney function, so kidney function tests are important during treatment.
- Bone density loss: Prolonged use can affect bone mineral density, leading to a higher risk of fractures.
- Lactic acidosis: A rare but serious side effect that involves a buildup of lactic acid in the blood.
- Hepatotoxicity: Liver toxicity, particularly in patients with preexisting liver conditions.
Precautions:
- Renal function: Monitoring of renal function is required before and during treatment.
- Liver disease: Patients with a history of liver disease, including hepatitis B or C, should be closely monitored.
- Pregnancy: Tenvir EM is classified as Pregnancy Category B and should be used during pregnancy only if clearly needed.
Monitoring:
- Renal function: Kidney function should be regularly monitored with tests for creatinine clearance.
- Liver function: Liver enzymes and hepatitis B or C status should be regularly checked during treatment.
Storage:
Store Tenvir EM tablets at room temperature (15°C to 30°C) in a dry place, away from light. Keep out of reach of children.
Conclusion:
Tenvir EM is a highly effective combination therapy for managing HIV infection and reducing the risk of HIV transmission in high-risk individuals. Regular monitoring for side effects such as kidney dysfunction and bone health is essential for ensuring treatment safety.
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Hepcvel Sofosbuvir And Velpatasvir Tablet
Product Price: Rs 2,500 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg+ 100 mg |
| Pack Size | 28 tablets |
| Brand | Hepcvel 400 mg/100 mg Tablet |
| Manufacturer | Cipla Ltd |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Hepcvel (Sofosbuvir and Velpatasvir) Tablet
Overview:
Hepcvel is a combination tablet containing Sofosbuvir (400 mg) and Velpatasvir (100 mg), used for the treatment of chronic hepatitis C virus (HCV) infection in adults. This combination therapy targets different stages of the HCV lifecycle, helping to reduce viral replication and improve liver function. Sofosbuvir is a nucleotide analog that inhibits the NS5B polymerase, while Velpatasvir inhibits the NS5A protein, which is crucial for the virus's replication and assembly. Hepcvel is effective across all major HCV genotypes (1-6).
Indications:
Hepcvel is indicated for the treatment of chronic hepatitis C in adults with genotypes 1, 2, 3, 4, 5, or 6. It is used both for treatment-naive patients and those who have previously been treated for HCV. Hepcvel can be prescribed as a monotherapy or in combination with ribavirin for certain patients, especially in more advanced stages of the disease.
Mechanism of Action:
- Sofosbuvir inhibits the NS5B polymerase, an enzyme required for HCV replication.
- Velpatasvir targets and inhibits the NS5A protein, which plays a role in viral replication and assembly.
By targeting two different parts of the virus, Hepcvel effectively suppresses HCV replication, reducing the viral load and promoting a sustained virologic response (SVR).
Dosage and Administration:
- Recommended Dose: The usual dose of Hepcvel is one tablet (400 mg Sofosbuvir / 100 mg Velpatasvir) taken once daily, with or without food.
- Administration: The tablet should be swallowed whole with a glass of water. Do not chew or crush the tablet.
- Missed Dose: If a dose is missed, take it as soon as possible, unless it's almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects may include:
- Fatigue, headache, nausea, insomnia, and diarrhea.
Serious side effects include: - Liver issues, severe allergic reactions, and bradycardia when combined with amiodarone.
Precautions:
- Renal Impairment: Hepcvel is generally safe in patients with mild to moderate renal impairment, but caution is advised for those with severe kidney disease.
- Pregnancy: Sofosbuvir should not be used during pregnancy unless combined with ribavirin, which is contraindicated due to teratogenic effects.
- Drug Interactions: Hepcvel may interact with other drugs, such as HIV medications, anticonvulsants, and certain heart medications. Inform your doctor of all medications you're currently taking.
Monitoring:
Regular monitoring of liver function, HCV RNA levels, and kidney function is recommended during treatment. Periodic monitoring of cardiac function may be necessary when taking Hepcvel with amiodarone.
Storage:
Store Hepcvel at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Hepcvel is a highly effective treatment for chronic hepatitis C. By combining two potent antiviral agents, Sofosbuvir and Velpatasvir, it targets key stages of HCV replication and reduces the viral load. Hepcvel is generally well-tolerated, and regular monitoring helps ensure treatment safety and effectiveness.
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Novisof Sofosbuvir 400 mg Tablets
Product Price: Rs 3,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | Novisof |
| Pack Size | 28 tablets |
| Packaging Size | 28 Tablet in 1 Bottle |
| Composition | Sofosbuvir 400 mg |
| Brand Name | Novisof Tablets |
| Manufactured | Wockhardt Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Novisof Sofosbuvir 400 mg Tablets
Overview:
Novisof Sofosbuvir 400 mg Tablets are an antiviral medication used to treat chronic hepatitis C virus (HCV) infection. Sofosbuvir is a direct-acting antiviral (DAA) that works by inhibiting the NS5B polymerase enzyme, which is essential for the replication of the hepatitis C virus. By blocking viral replication, Sofosbuvir helps reduce the viral load in the body, improving liver function and preventing the progression of liver damage caused by HCV.
Indications:
Novisof Sofosbuvir 400 mg Tablets are indicated for:
- Chronic hepatitis C virus (HCV) infection: In combination with other antivirals (e.g., ledipasvir, ribavirin) for the treatment of adults with HCV genotype 1, 2, 3, 4, 5, or 6 infections.
Mechanism of Action:
Sofosbuvir is a nucleotide analogue inhibitor of the NS5B polymerase, a viral enzyme involved in the replication of HCV. By inhibiting this enzyme, Sofosbuvir prevents the virus from replicating and producing new viral particles, leading to a decrease in viral load and promoting viral eradication in infected individuals.
Dosage and Administration:
- Recommended Dose: The usual dose of Novisof Sofosbuvir 400 mg is one tablet once daily, taken with or without food.
- Administration: The tablet should be swallowed whole with water.
- Missed Dose: If a dose is missed, take it as soon as possible, unless it’s close to the time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, insomnia, and diarrhea.
Serious side effects may include: - Severe liver problems, bradycardia (slowed heart rate) when combined with certain medications, and allergic reactions like rash or swelling.
Precautions:
- Renal impairment: Use with caution in patients with kidney problems.
- Pregnancy and breastfeeding: Not recommended for use during pregnancy unless specifically prescribed with ribavirin.
Monitoring:
- Regular monitoring of liver function, viral load, and kidney function may be required during treatment.
Storage:
Store Novisof Sofosbuvir 400 mg Tablets at room temperature (15°C to 30°C), away from heat and moisture. Keep out of reach of children.
Conclusion:
Novisof Sofosbuvir 400 mg Tablets are a key medication in the treatment of chronic hepatitis C. When used in combination with other antivirals, they help reduce viral replication, improve liver health, and offer a high cure rate for HCV infections. Proper administration and monitoring are crucial for achieving optimal results.
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Takfa Tacrolimus 0.5 mg Capsules
Product Price: Rs 150 / BoxGet Best Price
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Product Details:
| Strength | 0.5 mg |
| Brand | Takfa |
| Release Form | Prolonged Release |
| Packaging Type | 6*10 Capsules |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Composition | Tacrolimus 0.5 Capsules |
| Brand Name | Takfa 0.5 mg |
| Treatment | Prevention of organ rejection in transplant patients |
Takfa Tacrolimus Capsules
Overview:
Takfa Tacrolimus Capsules are used to prevent organ transplant rejection and manage certain autoimmune conditions. Tacrolimus is an immunosuppressive medication that works by inhibiting T-cell activation, thus preventing the immune system from attacking the transplanted organ. It is commonly prescribed for kidney, liver, and heart transplant patients and can also be used to treat psoriasis and eczema when other treatments fail.
Indications:
Takfa Tacrolimus is indicated for:
- Prevention of organ transplant rejection (kidney, liver, heart).
- Autoimmune diseases like severe psoriasis and eczema.
Mechanism of Action:
Tacrolimus binds to FKBP-12 and inhibits calcineurin, a protein involved in T-cell activation. This reduces the production of cytokines, molecules that drive the immune response, thereby preventing organ rejection or autoimmune reactions.
Dosage and Administration:
- Starting Dose: Generally, 0.1–0.2 mg/kg/day for transplant patients, adjusted based on response.
- Administration: Take Takfa Tacrolimus orally once or twice daily, with or without food. It’s important to take it at the same time every day.
- Missed Dose: If you miss a dose, take it as soon as possible unless it’s near the time for the next dose.
Side Effects:
Common side effects include:
- Headache, tremors, nausea, high blood pressure, and insomnia.
Serious effects may include: - Kidney damage, increased infection risk, and neurotoxicity.
Precautions:
- Kidney function should be monitored regularly.
- Avoid exposure to infections due to immunosuppression.
- Pregnancy: Use only if necessary, under medical supervision.
Monitoring:
- Regular blood tests to monitor tacrolimus levels.
- Monitor kidney function and electrolyte levels.
Storage:
Store at room temperature (15–30°C), away from heat and moisture.
Conclusion:
Takfa Tacrolimus Capsules are effective in preventing organ rejection and treating autoimmune diseases. Regular monitoring and adherence to dosing are essential for safety and efficacy.
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Resof Sofosbuvir 400 mg Tablets
Product Price: Rs 4,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | Resof |
| Pack Size | 28 tablets |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Brand Name | Resof-L 400 mg tablet |
| Manufactured | Dr Reddy's Laboratories Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Resof Sofosbuvir 400 mg Tablets
Overview:
Resof Sofosbuvir 400 mg Tablets is an antiviral medication used for the treatment of chronic hepatitis C virus (HCV) infection. Sofosbuvir, a nucleotide analogue, works by inhibiting the NS5B RNA-dependent RNA polymerase enzyme, which is essential for the replication of the HCV. By blocking this enzyme, Sofosbuvir prevents the virus from reproducing, helping to reduce the viral load in the body and improve liver function.
Indications:
Resof Sofosbuvir 400 mg Tablets is indicated for the treatment of chronic HCV infection in adults. It is commonly used as part of combination therapy with other antiviral agents like Ledipasvir or Ribavirin, depending on the genotype of the virus.
Mechanism of Action:
Sofosbuvir is a nucleotide analogue inhibitor that targets the NS5B polymerase enzyme involved in the replication of the hepatitis C virus. By inhibiting this enzyme, Sofosbuvir prevents the synthesis of new viral RNA, thereby blocking the viral replication cycle and reducing the viral load.
Dosage and Administration:
- Recommended Dose: The standard dose is one tablet of Resof Sofosbuvir 400 mg taken once daily.
- Administration: The tablet should be swallowed whole with or without food.
- Missed Dose: If a dose is missed, take it as soon as possible. If it’s near the time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take two doses at once.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, insomnia, and diarrhea.
Serious side effects may include: - Liver damage, bradycardia (when taken with amiodarone), and severe allergic reactions (e.g., rash, swelling, difficulty breathing).
Precautions:
- Renal Impairment: Use with caution in patients with kidney problems, particularly in those with severe renal impairment.
- Pregnancy: Not recommended during pregnancy unless prescribed with ribavirin, which can cause birth defects.
Monitoring:
- Regular monitoring of liver function, viral load, and renal function is necessary during treatment.
Storage:
Store Resof Sofosbuvir 400 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep the tablets out of reach of children.
Conclusion:
Resof Sofosbuvir 400 mg Tablets are an effective treatment option for chronic hepatitis C infection. When used as part of combination therapy, Sofosbuvir helps reduce the viral load, improves liver health, and can lead to a sustained virologic response (SVR), offering a high cure rate for many patients.
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Sovihep Sofosbuvir Tablets
Product Price: Rs 3,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | SoviHep |
| Pack Size | 28 tablets |
| Packaging Size | 28 Tablets in 1 Bottle |
| Composition | Sofosbuvir 400 mg |
| Brand Name | Sovihep 400 mg tablet |
| Manufactured | Zydus Cadila |
| Usage/Application | Chronic Hepatitis C Virus (Hcv) Infection |
Sovihep Sofosbuvir Tablets
Overview:
Sovihep is a brand of Sofosbuvir, an antiviral medication used to treat chronic hepatitis C virus (HCV) infection. Sofosbuvir is a nucleoside analog inhibitor that targets the NS5B RNA polymerase, an enzyme essential for the replication of the HCV virus. By inhibiting this enzyme, Sovihep prevents viral RNA replication, which helps to reduce viral load, improve liver function, and prevent further liver damage associated with chronic HCV infection.
Indications:
Sovihep Sofosbuvir Tablets are indicated for the treatment of:
- Chronic Hepatitis C (HCV): Used to treat HCV genotypes 1, 2, 3, and 4.
- HCV/HIV Co-infection: Used in combination with other antiviral drugs to treat patients co-infected with HIV and HCV.
Mechanism of Action:
Sofosbuvir, the active ingredient in Sovihep, works by inhibiting the NS5B RNA polymerase enzyme, which is crucial for the replication of the HCV virus. By blocking this enzyme, Sofosbuvir prevents the virus from replicating its RNA, leading to reduced viral load and helping the immune system control and eliminate the virus.
Dosage and Administration:
- Recommended Dose: The standard dose is one 400mg tablet once daily, with or without food.
- Administration: Swallow the tablet whole with water. Do not crush or chew the tablet.
- Missed Dose: If you miss a dose, take it as soon as possible unless it’s close to your next scheduled dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, insomnia, and diarrhea.
Serious side effects may include: - Liver toxicity: Liver function should be monitored regularly.
- Allergic reactions: Rare, but may include rash, swelling, or difficulty breathing.
- Bradycardia: Slow heart rate, particularly if taken with certain medications.
Precautions:
- Pregnancy: Sovihep should not be used during pregnancy unless clearly needed.
- Drug Interactions: Inform your doctor about all other medications, including over-the-counter drugs.
- Renal Impairment: Dose adjustments may be necessary for patients with severe kidney issues.
Storage:
Store Sovihep Sofosbuvir Tablets at room temperature (20°C to 25°C), away from light and moisture. Keep the tablets in the original packaging and out of the reach of children.
Conclusion:
Sovihep Sofosbuvir Tablets are an effective treatment for chronic hepatitis C. By inhibiting viral replication, Sofosbuvir reduces the viral load and promotes liver health. Regular monitoring for side effects and liver function is important to ensure safe and effective treatment.
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2mg Tacrolimus Tablets
Product Price: Rs 500 / BoxGet Best Price
Product Brochure
Product Details:
| Brand | Takfa |
| Release Form | Immediate Release |
| Strength | 2 mg |
| Packaging Type | 10 Tablets in 1 Strip |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Composition | Tacrolimus 2 mg |
| Brand Name | Takfa 2 mg Tablets |
| Treatment | Ongoing Hepatitis B Infection (Hbv) Contamination |
2 mg Tacrolimus Tablets
Overview:
Tacrolimus is an immunosuppressive medication used to prevent organ rejection in transplant patients and to treat certain autoimmune diseases, such as rheumatoid arthritis and lupus nephritis. It is a calcineurin inhibitor that works by suppressing the activity of the immune system to prevent it from attacking the transplanted organ or the body’s own tissues in autoimmune diseases. Tacrolimus helps to maintain the function of transplanted organs, such as kidneys, livers, and hearts.
Indications:
2 mg Tacrolimus Tablets are indicated for:
- Prevention of Organ Rejection: In patients who have undergone kidney, liver, or heart transplantation.
- Autoimmune Disorders: Such as rheumatoid arthritis and lupus nephritis when other treatments have failed.
Mechanism of Action:
Tacrolimus works by inhibiting calcineurin, a protein that activates T-cells, which are involved in immune responses. By suppressing calcineurin activity, Tacrolimus reduces the production of interleukin-2 (IL-2), which is essential for T-cell activation. This results in immunosuppression, helping to prevent the immune system from attacking the transplanted organ or the body’s own tissues in autoimmune diseases.
Dosage and Administration:
- Recommended Dose: The typical starting dose is 0.075 mg/kg/day (usually taken in two doses per day).
- Administration: Take the tablet with or without food, swallowed whole with water.
- Missed Dose: If you miss a dose, take it as soon as you remember, unless it's close to your next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Headache, tremors, nausea, and insomnia.
Serious side effects may include: - Kidney Toxicity: Tacrolimus can cause kidney problems, so kidney function should be monitored regularly.
- Increased Risk of Infection: Due to immunosuppression, there is a higher risk of infections.
- Hypertension: Elevated blood pressure may occur.
- Hyperglycemia: Increased blood sugar levels, especially in diabetic patients.
Precautions:
- Kidney Disease: Adjustments may be needed for patients with pre-existing kidney issues.
- Pregnancy and Breastfeeding: Tacrolimus should only be used during pregnancy if clearly needed and with caution during breastfeeding.
- Drug Interactions: Tacrolimus interacts with various medications, including certain antifungals, antibiotics, and antivirals. Inform your doctor about all medications you're taking.
Storage:
Store Tacrolimus Tablets at room temperature (20°C to 25°C), away from moisture and heat. Keep it in the original packaging, out of the reach of children.
Conclusion:
2 mg Tacrolimus Tablets are vital in preventing organ rejection after transplant surgery and managing certain autoimmune diseases. It is important to follow your doctor’s instructions closely and undergo regular monitoring to ensure the drug’s effectiveness and minimize risks, particularly kidney toxicity and infections.
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Cimivir 400 mg Tablet
Product Price: Rs 2,850 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | Cimivir |
| Pack Size | 28 tablets |
| Packaging Size | 28 Tablet in 1 Bottle |
| Composition | Sofosbuvir 400 mg |
| Brand Name | Cimivir 400 mg |
| Manufactured | Biocon |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Cimivir 400mg Tablet
Overview:
Cimivir (generic name Tenofovir disoproxil fumarate) is an antiretroviral medication used in the treatment of HIV-1 infection and chronic hepatitis B. It works by inhibiting the action of the reverse transcriptase enzyme, which is crucial for the replication of the HIV virus. By blocking this enzyme, Cimivir helps reduce the viral load, improve immune function, and prevent the progression of HIV to AIDS. It is also effective in treating hepatitis B by suppressing viral replication.
Indications:
Cimivir 400mg Tablet is indicated for:
- HIV-1 Infection: Used in combination with other antiretroviral agents to treat HIV-1 infection in adults and pediatric patients.
- Chronic Hepatitis B: Used for the treatment of chronic hepatitis B infection in adults with evidence of active viral replication and liver disease.
Mechanism of Action:
Cimivir is a nucleotide reverse transcriptase inhibitor (NRTI). Once inside the cell, it is converted into its active form, tenofovir diphosphate, which inhibits HIV reverse transcriptase, preventing the conversion of viral RNA into DNA. This prevents viral replication and reduces the viral load. For hepatitis B, it suppresses the replication of the hepatitis B virus (HBV).
Dosage and Administration:
- Recommended Dose: The typical dose for adults is 400 mg once daily for HIV-1 infection and hepatitis B.
- Administration: Cimivir should be taken orally with or without food. The tablet should be swallowed whole with water.
- Missed Dose: If a dose is missed, take it as soon as you remember, unless it is nearly time for the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Nausea, diarrhea, fatigue, headache, and dizziness.
Serious side effects may include: - Liver toxicity: Elevated liver enzymes or liver failure, particularly in patients with pre-existing liver conditions.
- Renal toxicity: Kidney problems, including renal failure, can occur in some patients.
- Bone issues: Long-term use may cause bone density loss or fractures.
Precautions:
- Kidney disease: Caution is needed for patients with renal impairment, and kidney function should be monitored.
- Liver disease: Regular liver function tests are necessary for those with hepatitis B or a history of liver issues.
- Pregnancy: Cimivir is generally considered safe during pregnancy, but should only be used under the guidance of a healthcare provider.
Monitoring:
- Renal function: Regular monitoring of serum creatinine and kidney function is recommended.
- Liver function: Periodic monitoring of liver enzymes is necessary.
- Bone health: Long-term use requires monitoring of bone mineral density.
Storage:
Store Cimivir 400mg Tablet at room temperature (20°C to 25°C), away from light, heat, and moisture. Keep the tablet in its original container and out of reach of children.
Conclusion:
Cimivir 400mg Tablet is a key medication for managing HIV-1 infection and chronic hepatitis B. It helps reduce viral load and improve immune function, but regular monitoring is required to manage potential side effects, especially related to kidney, liver, and bone health.
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Resof L Ledipasvir 90 Mg Sofosbuvir 400 Mg
Product Price: Rs 4,350 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 90 mg+400 mg |
| Brand | Resof-L |
| Pack Size | 28 Tablets in 1 Bottle |
| Dose/Strength | 90 mg/400 mg |
| Salt Composition | Ledipasvir 90 mg + Sofosbuvir 400 mg |
| Brand Name | Resof-L 400 mg tablet |
| Manufactured | Dr Reddy's Laboratories Ltd |
| Usage/Application | Chronic hepatitis C virus (HCV) infection |
Resof L (Ledipasvir 90mg / Sofosbuvir 400mg)
Overview:
Resof L is a fixed-dose combination of two antiviral drugs, Ledipasvir (90mg) and Sofosbuvir (400mg). It is used to treat chronic hepatitis C virus (HCV) infection in adults. This combination works by inhibiting specific enzymes essential for the replication of the HCV virus, thus reducing the viral load and preventing further liver damage. Resof L is used for the treatment of HCV genotype 1 infection, and in some cases, in combination with other antiviral agents for other genotypes.
Indications:
Resof L is indicated for:
- Chronic Hepatitis C: For the treatment of adults with HCV genotype 1 infection, with or without cirrhosis.
- Co-infection with HIV: Can be used in patients with both HIV and chronic HCV infection.
- Other Genotypes: In some cases, used in combination with additional antiviral agents to treat other HCV genotypes.
Mechanism of Action:
- Ledipasvir is an NS5A inhibitor that prevents the replication of the HCV virus by binding to the NS5A protein, which is necessary for viral replication and assembly.
- Sofosbuvir is an NS5B polymerase inhibitor that blocks the RNA polymerase enzyme, which is essential for viral RNA synthesis. Together, these drugs work synergistically to inhibit different stages of the HCV life cycle, significantly reducing the viral load and improving liver function.
Dosage and Administration:
- Recommended Dose: The usual dose is one tablet of Resof L once daily, taken with or without food.
- Administration: Swallow the tablet whole; do not crush or chew.
- Missed Dose: If you miss a dose, take it as soon as possible, unless it is close to the next scheduled dose. Do not double the dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, and diarrhea.
Serious side effects may include: - Hepatotoxicity: Liver function should be monitored during treatment.
- Bradycardia: Risk of slow heart rate when used with certain other medications.
- Rash and severe allergic reactions.
Precautions:
- Pregnancy: Not recommended during pregnancy unless clearly needed.
- Drug Interactions: Can interact with other medications, so consult your healthcare provider about all medications you are taking.
- Renal Impairment: Dose adjustments may be required in patients with severe renal impairment.
Storage:
Store Resof L at room temperature (20°C to 25°C), away from light and moisture, and out of the reach of children.
Conclusion:
Resof L (Ledipasvir/Sofosbuvir) is an effective treatment for chronic hepatitis C. It works by inhibiting key viral enzymes, helping to reduce viral load and improve liver health. Regular monitoring for side effects and interactions with other drugs is crucial for safety.
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Resof Total 400 mg/100 mg Tablet
Product Price: Rs 6,400 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 100 mg+400 mg |
| Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Pack Size | 28 tablets |
| Dose/Strength | 400 mg/100 mg |
| Pack Type | 28 Tablets in 1 Bottle |
| Salt Composition | Sofosbuvir 400 mg + Velpatasvir 100 mg |
| Brand Name | Resof Total 400 mg/100 mg Tablet |
| Manufactured By | Dr Reddy's Laboratories Ltd |
| Treatment Of | Chronic hepatitis C virus (HCV) infection |
Resof Total 400mg/100mg Tablet
Overview:
Resof Total 400mg/100mg Tablet is a fixed-dose combination medication used in the treatment of chronic hepatitis C. It contains Sofosbuvir (400 mg) and Velpatasvir (100 mg), both direct-acting antiviral (DAA) agents that work by targeting the hepatitis C virus (HCV). Sofosbuvir inhibits the viral RNA polymerase, preventing viral replication, while Velpatasvir inhibits the HCV NS5A protein, which is essential for viral replication and assembly. This combination therapy is highly effective against all HCV genotypes.
Indications:
Resof Total 400mg/100mg Tablet is indicated for:
- Chronic Hepatitis C: Used for the treatment of chronic hepatitis C infection in adults, regardless of HCV genotype. It is often prescribed for patients with or without cirrhosis or in combination with other medications, depending on the individual’s condition.
Mechanism of Action:
Sofosbuvir is a nucleotide analog inhibitor, blocking the NS5B polymerase enzyme, which is necessary for the replication of HCV RNA. Velpatasvir is an NS5A inhibitor, preventing the formation of the viral replication complex. Together, these medications inhibit multiple steps of the HCV lifecycle, leading to a significant reduction in viral load and, eventually, viral eradication.
Dosage and Administration:
- Recommended Dose: The usual dose is one tablet (400mg Sofosbuvir/100mg Velpatasvir) once daily with or without food.
- Administration: The tablet should be swallowed whole with a glass of water.
- Missed Dose: If a dose is missed, take it as soon as possible, unless it is close to the time for the next dose.
Side Effects:
Common side effects include:
- Fatigue, headache, nausea, and diarrhea.
Serious side effects may include: - Hepatitis reactivation in patients co-infected with HBV.
- Severe liver problems, especially in patients with cirrhosis.
- Rash or other allergic reactions.
Precautions:
- Liver Disease: Monitor liver function, especially in patients with pre-existing liver conditions.
- Pregnancy: Use caution during pregnancy, especially if co-administered with ribavirin, which is contraindicated during pregnancy.
- Drug Interactions: May interact with other medications, particularly those affecting liver enzymes (CYP3A).
Storage:
Store Resof Total 400mg/100mg Tablets at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Resof Total 400mg/100mg Tablet offers a convenient, once-daily treatment for chronic hepatitis C, with a high cure rate and a manageable side effect profile. Regular monitoring for liver function and any drug interactions is essential during treatment.
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