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Anti Cancer Tablets
Our range of products include abiraterone acetate tablets (abione 250mg tablets), abstet abiraterone acetate 250 mg tablet, abiraterone acetate tablets (abirakast 250 mg tablet), abiraterone acetate tablets (ahabir 250mg tablet), abiraterone acetate tablet (arbitus tablet 500 mg) and zelgor abiraterone 250 mg tablets.
Abiraterone Acetate Tablets (Abione 250mg Tablets)
Product Price: Rs 3,500 / BoxGet Best Price
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Product Details:
| Strength | 250 mg |
| Form | Tablet |
| Prescription/Non prescription | Prescription |
| Box Contain | 120 Tab |
| Composition | Abiraterone Acetate |
Abiraterone Acetate Tablets (Abione 250mg Tablets)
Overview:
Abiraterone Acetate (Abione 250mg Tablets) is a medication used primarily for the treatment of prostate cancer, particularly in patients with metastatic castration-resistant prostate cancer (mCRPC). It works by inhibiting cytochrome P450 17A1 (CYP17A1), an enzyme involved in the production of androgens (male hormones like testosterone) in the body. By lowering androgen levels, Abiraterone reduces the growth of prostate cancer cells that rely on these hormones for proliferation.
Indications:
Abione 250mg Tablets are indicated for:
- Metastatic Castration-Resistant Prostate Cancer (mCRPC): Used in combination with prednisone to treat mCRPC, particularly in patients who have failed androgen deprivation therapy.
- Castration-Sensitive Prostate Cancer: May also be used in combination with other therapies for patients whose cancer is sensitive to castration.
Mechanism of Action:
Abiraterone acetate is a CYP17A1 inhibitor. CYP17A1 is responsible for producing androgens in the adrenal glands and prostate. By inhibiting this enzyme, Abiraterone reduces testosterone and other androgen production. This action deprives prostate cancer cells of the hormones they need to grow, leading to a reduction in tumor size and slowing disease progression.
Dosage and Administration:
- Recommended Dose: The typical dose is 1000 mg (four 250 mg tablets) once daily, taken with or without food.
- Administration: The tablets should be swallowed whole with water.
- Missed Dose: If a dose is missed, it should be taken as soon as possible, unless it is near the time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Fatigue, joint swelling, hot flashes, and diarrhea.
Serious side effects may include: - Hypertension (high blood pressure), hypokalemia (low potassium levels), and liver toxicity.
- Adrenal insufficiency: A potential issue due to reduced cortisol levels from inhibiting CYP17A1.
Precautions:
- Liver Function: Regular monitoring of liver enzymes is essential as Abiraterone may cause liver toxicity.
- Adrenal Insufficiency: Monitor for signs of adrenal insufficiency, and consider hydrocortisone supplementation.
- Pregnancy: Contraindicated in pregnant women as it may harm the fetus.
Storage:
Store Abione 250mg Tablets at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion:
Abione 250mg Tablets (Abiraterone acetate) is an effective treatment for advanced prostate cancer. By inhibiting androgen production, it slows the growth of cancer cells, improving outcomes in patients with metastatic castration-resistant prostate cancer. Regular monitoring is important to ensure safe and effective use of the medication.
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Abstet Abiraterone Acetate 250 mg Tablet
Product Price: Rs 35,000 / BottleGet Best Price
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Product Details:
| Strength | 250 mg |
| Packaging Size | 120 Tablets in 1 Bottle |
| Composition | Abiraterone Acetate 250 mg |
| Brand Name | Abstet 250 mg Tablet |
| Manufacturer | Biocon |
| Treatment | Prostate Cancer |
| Manufactured by | Biocon |
| Medicine form | Tablet |
| Medicine name | Abiraterone acetate tablets |
| Medicine strength | 250mg |
| Packaging size | 120 |
| Packaging type | Box |
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Abiraterone Acetate Tablets (Abirakast 250 mg Tablet)
Product Price: Rs 13,500 / BottleGet Best Price
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Product Details:
| Strength | 250 mg |
| Packaging Size | 120 Tablets in 1 Bottle |
| Composition | Abiraterone Acetate 250 mg |
| Brand | Abirakast 250 mg Tablet |
| Manufacturer | Aprazer Healthcare Pvt Ltd |
| Treatment | Prostate cancer |
| Medicine brand | Abirakast |
| Medicine form | Tablet |
| Medicine name | Abiraterone acetate tablets ip |
| Medicine strength | 250 mg |
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Abiraterone Acetate Tablets (Ahabir 250mg Tablet)
Product Price: Rs 22,500 / BoxGet Best Price
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Product Details:
| Strength | 250 mg |
| Packaging Size | 120 Tablets in 1 Bottle |
| Composition | Abiraterone Acetate 250 mg |
| Brand | Ahabir 250 mg Tablet |
| Manufacturer | Hetero Drugs Ltd |
| Treatment | Prostate Cancer |
| Medicine name | abiraterone acetate tablets ip 250 mg ahabir เคเคนเคพเคตเฅเคฐ |
| Medicine strength | 250 mg |
| Packaging size | 120 |
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Abiraterone Acetate Tablet (arbitus Tablet 500 mg)
Product Price: Rs 30,000 / BottleGet Best Price
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Product Details:
| Strength | 500 mg |
| Packaging Size | 60 Tablets In 1 Bottle |
| Composition | Abiraterone Acetate 500 mg |
| Brand Name | Arbitus Tablet |
| Manufacturer | Dr Reddy's Laboratories Ltd |
| Treatment | Prostate cancer |
| Medicine brand | Arbitus™ 500 |
| Medicine form | Tablet |
| Medicine name | Abiraterone acetate tablets i.p. |
| Medicine strength | 500mg |
| Packaging size | 60 tablets |
| Packaging type | Bottle |
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Zelgor Abiraterone 250 mg Tablets
Product Price: Rs 5,000 / BottleGet Best Price
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Product Details:
| Strength | 250 mg |
| Brand | Zelgor |
| Tablets per Pack | 120 Tablets |
| Packaging Size | 120 Tablets in 1 Bottle |
| Composition | Abiraterone Acetate 250 mg |
| Brand Name | Zelgor 250 mg |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Treatment | Prostate cancer |
Zelgor Abiraterone 250mg Tablets
Overview:
Zelgor (Abiraterone Acetate) is an oral medication used in the treatment of prostate cancer. It is primarily indicated for patients with metastatic castration-resistant prostate cancer (mCRPC), a type of prostate cancer that has spread and does not respond to hormone therapy. Abiraterone works by inhibiting the enzyme CYP17A1, which is involved in the production of androgens (male hormones) outside the testes. By blocking this enzyme, Zelgor reduces androgen levels, which in turn helps to slow the growth of prostate cancer cells that rely on androgens for growth.
Indications:
Zelgor 250mg Tablets are indicated for:
- Metastatic Castration-Resistant Prostate Cancer (mCRPC): For patients who are receiving chemotherapy or hormonal therapy and whose cancer has progressed despite treatments.
- Castration-Sensitive Prostate Cancer (CSPC): In combination with prednisone, for patients who have not yet progressed to castration-resistant disease.
Mechanism of Action:
Abiraterone acetate is a selective CYP17A1 inhibitor. By inhibiting this enzyme, Zelgor reduces the synthesis of androgens (including testosterone) in the adrenal glands, prostate, and tumor tissue, leading to a decrease in the androgen-driven growth of prostate cancer cells. This mechanism helps to slow disease progression and improve survival in men with advanced prostate cancer.
Dosage and Administration:
- Recommended Dose: The typical dose for mCRPC is 1000 mg (four 250 mg tablets) taken once daily.
- Administration: Zelgor should be taken on an empty stomach at least one hour before or two hours after food. It should be swallowed whole with water, not chewed or crushed.
- Missed Dose: If a dose is missed, it should be taken as soon as possible, unless it's almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Fatigue
- Joint pain
- Hot flashes
- Diarrhea
- Elevated liver enzymes Serious side effects may include:
- Hypertension (high blood pressure)
- Liver toxicity
- Adrenal insufficiency
- Cardiovascular events
Precautions:
- Liver Function: Liver enzymes should be monitored regularly due to the risk of liver damage.
- Adrenal Insufficiency: Patients may need steroid therapy to prevent adrenal insufficiency.
- Pregnancy: Zelgor is contraindicated in pregnancy due to potential harm to the fetus.
Storage:
Store Zelgor at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion:
Zelgor 250mg Tablets offer an important treatment option for patients with metastatic castration-resistant prostate cancer. Regular monitoring and proper dosing are essential for managing side effects and ensuring the effectiveness of treatment.
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Abura Abiraterone Acetate 250 mg Tablet
Product Price: Rs 22,500 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Brand | Abura |
| Tablets per Pack | 120 Tablets |
| Treatment | Prostate cancer |
| Packaging Size | 120 Tablets in 1 Bottle |
| Composition | Abiraterone Acetate 250 mg |
| Brand Name | Abura 250 mg Tablet |
| manufacturer | Msn Laboratories (India) |
Abura Abiraterone Acetate 250mg Tablets
Overview:
Abura (Abiraterone Acetate) 250mg is an oral medication primarily used to treat metastatic castration-resistant prostate cancer (mCRPC). It is a selective inhibitor of the enzyme CYP17A1, which is involved in the production of androgens (male hormones). By inhibiting this enzyme, Abura reduces androgen levels, which are known to promote the growth of prostate cancer cells. The drug is often used in combination with prednisone to help manage inflammation and side effects.
Indications:
Abura 250mg is indicated for:
- Metastatic Castration-Resistant Prostate Cancer (mCRPC): Used in combination with prednisone for the treatment of advanced prostate cancer that no longer responds to hormonal therapy.
- Metastatic High-Risk Prostate Cancer: Used in combination with androgen deprivation therapy (ADT) for patients at high risk of progression.
Mechanism of Action:
Abiraterone inhibits the enzyme CYP17A1, which is crucial in the synthesis of androgens in the adrenal glands, testes, and prostate tumor cells. By blocking this enzyme, Abura reduces the amount of testosterone and other androgens, slowing the growth and spread of cancer cells that rely on these hormones for growth.
Dosage and Administration:
- Recommended Dose: The usual dose is 250mg once daily, taken orally with food. The dose may be adjusted based on patient response and tolerability.
- Administration: Abura should be taken at the same time each day to ensure consistent blood levels. It is often prescribed with prednisone to mitigate side effects.
- Missed Dose: If a dose is missed, it should be taken as soon as remembered unless it’s close to the time for the next dose.
Side Effects:
Common side effects include:
- Fatigue
- Hot flashes
- Joint pain
- Increased blood pressure
- Liver enzyme elevation Serious side effects include:
- Cardiovascular problems, including heart failure
- Liver toxicity
- Low potassium levels (hypokalemia)
- Adrenal insufficiency
Precautions:
- Liver Function: Patients should have liver function tests before starting treatment and periodically during therapy.
- Pregnancy and Breastfeeding: Contraindicated due to the risk to the fetus or infant.
- Blood Pressure: Regular monitoring is needed due to the potential for elevated blood pressure.
Storage:
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Abura Abiraterone Acetate 250mg is an effective treatment for metastatic prostate cancer. Careful monitoring of blood pressure, liver function, and potassium levels is essential to minimize risks and ensure treatment effectiveness.
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Abiraterone Acetate Tablets (Abiratas 500 mg Tablet)
Product Price: Rs 20,000 / BottleGet Best Price
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Product Details:
| Strength | 500 mg |
| Brand | Abiratas |
| Tablets per Pack | 60 Tablets |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Treatment | Prostate Cancer |
| Packaging Size | 60 Tablets in 1 Bottle |
| Composition | Abiraterone Acetate 500 mg |
| Brand Name | Abiratas 500 mg Tablet |
Abiraterone Acetate Tablets (Abiratas 500 mg Tablet)
Overview:Abiratas 500 mg Tablets contain Abiraterone Acetate, a potent anti-androgen therapy used in the treatment of prostate cancer, particularly in cases of metastatic castration-resistant prostate cancer (mCRPC). Abiraterone works by inhibiting the enzyme CYP17A1, which plays a crucial role in the production of androgens (male hormones) like testosterone. By reducing androgen levels, Abiraterone helps to slow or stop the growth of androgen-dependent prostate cancer cells, making it an essential part of treatment for men with advanced prostate cancer.
Indications:Abiratas 500 mg Tablets are indicated for:
- Metastatic Castration-Resistant Prostate Cancer (mCRPC): Used in combination with prednisone for the treatment of mCRPC, especially in patients who have failed androgen deprivation therapy.
- Metastatic High-Risk Castration-Sensitive Prostate Cancer: For use in combination with androgen deprivation therapy (ADT) in patients with high-risk mCSPC.
- Post-Chemotherapy Prostate Cancer: For the treatment of metastatic prostate cancer after chemotherapy, also in combination with prednisone.
Abiraterone acetate blocks the CYP17A1 enzyme, which is responsible for the synthesis of androgens in the adrenal glands, testes, and prostate cancer cells. This inhibition lowers androgen levels, which are key drivers of prostate cancer cell growth. By depriving cancer cells of these hormones, Abiratas helps to slow the progression of prostate cancer, even in cases where other treatments like testosterone deprivation have failed.
Dosage and Administration:- Recommended Dose: 500 mg once daily, taken orally with prednisone (5 mg twice daily).
- Administration: Take Abiratas 500 mg Tablet on an empty stomach, at least 1 hour before or 2 hours after meals. Swallow whole with a glass of water. Do not crush or chew.
- Common Side Effects: Fatigue, joint pain, hot flashes, diarrhea, and fluid retention.
- Serious Side Effects: Liver toxicity, high blood pressure, adrenal insufficiency, and electrolyte imbalances (e.g., low potassium). Monitoring of liver function, electrolytes, and blood pressure is recommended.
- Liver Function: Regular liver function tests are required as Abiraterone can cause liver toxicity.
- Adrenal Insufficiency: Corticosteroids like prednisone are used to prevent adrenal insufficiency.
- Hypertension: Blood pressure should be regularly monitored during treatment.
- Pregnancy and Lactation: Contraindicated in pregnancy and breastfeeding.
Store Abiratas 500 mg Tablets at room temperature (15°C to 30°C), away from light, moisture, and heat. Keep out of reach of children.
Conclusion:Abiratas 500 mg Tablets are a vital treatment option for men with metastatic prostate cancer, including both castration-resistant and castration-sensitive forms. By inhibiting androgen production, it helps slow cancer progression and improves survival outcomes. Regular monitoring is essential to manage side effects and ensure optimal treatment.
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10mg Nolvadex Tamoxifen Tablet
Product Price: Rs 25 / StripGet Best Price
Minimum Order Quantity: 10 Strip
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Product Details:
| Strength | 10 mg |
| Dose/Strength | 10 mg |
| Brand Owner | AstraZeneca |
| Tablets per Pack | 30 Tablets |
| Form | Tablet |
| Packaging Type | Box |
| Brand | AstraZeneca |
| Shelf Life | 60 Months |
| Usage | Used To Treat Breast Cancer |
| Pack Size | 30 Tablets |
Overview:
Nolvadex 10 mg Tablets contain Tamoxifen Citrate, a selective estrogen receptor modulator (SERM) used primarily in the treatment and prevention of breast cancer. Tamoxifen works by binding to estrogen receptors on cancer cells, blocking the effects of estrogen, a hormone that can stimulate the growth of certain types of breast cancer cells. It is also used in fertility treatments and for other hormone-related conditions.
- Breast Cancer (Treatment): For estrogen receptor-positive (ER+) breast cancer in both premenopausal and postmenopausal women, typically after surgery, radiation, or chemotherapy, to reduce the risk of recurrence.
- Breast Cancer (Prevention): For high-risk women to reduce the risk of developing breast cancer.
- Ductal Carcinoma In Situ (DCIS): For preventive treatment in women with DCIS after surgery and radiation.
- Fertility Treatment: Occasionally used off-label to induce ovulation in women with anovulatory infertility (difficulty ovulating).
Tamoxifen is a SERM that binds to estrogen receptors, blocking the action of estrogen in estrogen receptor-positive (ER+) cancer cells. In some tissues, such as the bone and lipid metabolism, Tamoxifen acts as an estrogen agonist, mimicking estrogen's beneficial effects, such as bone density preservation and reducing the risk of heart disease.
Dosage and Administration:- Breast Cancer Treatment: The usual dose is 20 mg daily for 5 years.
- Breast Cancer Prevention: For high-risk women, the dose is usually 20 mg daily for 5 years.
- Fertility Treatment: The typical dose for ovulation induction is 10-20 mg daily, taken for 5 days during the early part of the menstrual cycle.
Administration: Take orally with or without food. Swallow the tablet whole without crushing or chewing.
Side Effects:Common: Hot flashes, nausea, vomiting, fatigue, vaginal discharge, and mood swings.
Serious: Endometrial cancer, blood clots, stroke, and uterine sarcoma.
Monitor: Regular pelvic exams and ultrasounds are recommended for women using Tamoxifen for prolonged periods.
- Endometrial Cancer: Tamoxifen may increase the risk of endometrial cancer. Women should be monitored for any abnormal vaginal bleeding.
- Thromboembolic Events: Tamoxifen can increase the risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism (PE).
- Pregnancy and Lactation: Contraindicated during pregnancy. Tamoxifen can harm the fetus and should not be used during pregnancy or while breastfeeding.
Store Nolvadex 10 mg Tablets at room temperature (15°C to 30°C), in a dry place, away from light and moisture. Keep out of reach of children.
Conclusion:Nolvadex 10 mg Tablets (Tamoxifen) is an effective treatment for estrogen receptor-positive breast cancer and is used for both treatment and prevention. By blocking estrogen's effects on breast cancer cells, it helps reduce the risk of cancer recurrence and development in high-risk women. Monitoring for endometrial cancer, blood clots, and other side effects is essential during therapy.
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Fempro Tablets Usp 2.5 mg
Product Price: Rs 60 / StripGet Best Price
Product Brochure
Product Details:
| Dose/Strength | 2.5 mg |
| Strength | 2.5 mg |
| Brand | Fempro |
| Tablets per Pack | 10 Tablets |
| Packaging Size | 10 Tablets in 1 Strip |
| Brand Name | Fempro Tablet |
| Manufacturer | Cipla Ltd |
| Treatment | Breast cancer |
| Composition | Letrozole 2.5 mg |
Fempro Tablets USP 2.5 mg
Overview:
Fempro (letrozole) is a medication used primarily for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is a type of aromatase inhibitor that works by decreasing the amount of estrogen in the body, which can slow or stop the growth of certain types of breast cancer that require estrogen to grow. Fempro is often used as an adjuvant treatment following surgery, radiation, or chemotherapy, and it may also be used in metastatic breast cancer.
Indications:
Fempro 2.5 mg is primarily indicated for:
- Adjuvant treatment of hormone receptor-positive breast cancer in postmenopausal women.
- Advanced or metastatic breast cancer in women who have already been treated with tamoxifen or other hormonal therapies.
- It may also be used for the treatment of early breast cancer to reduce recurrence risk.
Mechanism of Action:
Letrozole, the active ingredient in Fempro, works by inhibiting the enzyme aromatase, which converts androgens into estrogen. By reducing estrogen levels in the body, Fempro limits the growth of estrogen-dependent tumors, helping prevent cancer cell proliferation. It is most effective in postmenopausal women whose ovaries have stopped producing estrogen.
Dosage and Administration:
- Recommended Dose: The standard dose is 2.5 mg once daily, taken orally with or without food.
- Administration: Fempro tablets should be swallowed whole with water. The treatment duration is typically several years, depending on the patient's response and the type of cancer being treated.
- Missed Dose: If a dose is missed, it should be taken as soon as remembered, but do not take two doses at once.
Side Effects:
Common side effects include:
- Hot flashes
- Fatigue
- Joint pain
- Nausea
- Headache Serious side effects include:
- Osteoporosis: Fempro may decrease bone mineral density.
- Cardiovascular events: In rare cases, heart problems like arrhythmias.
- Liver dysfunction: Liver enzyme changes.
Precautions:
- Bone Health: Monitoring for bone density loss is recommended.
- Pregnancy and breastfeeding: Contraindicated as Fempro may harm the fetus or infant.
- Liver and kidney function: Periodic liver function tests are advised.
Storage:
Store at room temperature (20°C to 25°C), in a dry place, away from light. Keep out of reach of children.
Conclusion:
Fempro 2.5 mg tablets are a vital treatment for postmenopausal women with hormone receptor-positive breast cancer. Careful monitoring for side effects like bone density loss and cardiovascular events is necessary to ensure optimal treatment outcomes.
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Clomifene Tablets ( Clofi-50mg Tablets)
Product Price: Rs 215 / StripeGet Best Price
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Product Details:
| Strength | 50 mg |
| Brand | CLOFI |
| Packaging Type | Strip |
| Form | Tablet |
| Manufactured By | HBC Lifesciences Pvt Ltd |
| Usage/Application | Female infertility |
| Country of Origin | Made in India |
| Brand Name | CLOFI-50MG |
Indications: Clomifene is primarily indicated for:
- Treatment of ovulatory dysfunction in women who are trying to conceive. It is commonly used in cases of polycystic ovary syndrome (PCOS) or other conditions causing anovulation.
Mechanism of Action: Clomifene works as a selective estrogen receptor modulator (SERM). It stimulates the hypothalamus to release gonadotropin-releasing hormone (GnRH), which in turn increases the secretion of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. This promotes ovarian follicle development and ovulation.
Dosage and Administration:
- Typical Dosage: The usual starting dose is 50 mg taken orally once daily for 5 days, beginning on the 5th day of the menstrual cycle. If ovulation does not occur, the dose may be increased in subsequent cycles (up to 150 mg).
- Administration: Take the tablets as directed by a healthcare provider. It's important to follow the prescribed schedule and not to exceed the recommended dose.
Side Effects:
- Common: Hot flashes, mood swings, nausea, bloating, and breast tenderness.
- Serious: Ovarian hyperstimulation syndrome (OHSS), visual disturbances, and multiple pregnancies (e.g., twins).
Contraindications:
- Hypersensitivity to clomifene or any component of the formulation.
- Liver disease, uncontrolled adrenal or pituitary dysfunction, and ovarian cysts not related to PCOS.
Warnings and Precautions:
- Ovarian Hyperstimulation: Monitor for symptoms of OHSS, which can include abdominal pain, bloating, and rapid weight gain.
- Visual Disturbances: Caution patients to report any changes in vision.
- Multiple Pregnancies: Discuss the increased risk of multiple pregnancies with patients.
Drug Interactions: Clomifene may interact with other medications that affect hormonal balance or ovulation. Always inform healthcare providers of all medications being taken.
Storage: Store at room temperature (20°C to 25°C / 68°F to 77°F), away from moisture and light.
Patient Counseling Information:
- Advise patients to take the medication exactly as prescribed and to track their menstrual cycles.
- Discuss potential side effects and the importance of reporting any concerning symptoms.
- Encourage patients to maintain regular follow-up appointments for monitoring ovulation and overall health.
Clomifene Tablets (Clofi 50 mg) are a key treatment for women with ovulatory dysfunction seeking to conceive. Patients should be well-informed about the medication, its effects, and the importance of medical supervision during treatment. Always consult a healthcare provider for personalized medical advice.
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400 mg Apotinib Imatinib Mesylate Tablets
Product Price: Rs 564 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 400 mg |
| Dose/Strength | 400 mg |
| Brand | Apotinib |
| Tablets per Pack | 30 Tablets |
| Packaging Size | 30 Tablets |
| Composition | Imatinib mesylate (400 mg) |
| Manufacturer | BDR Pharmaceuticals Internationals Pvt |
| Brand Name | Apotinib 400 Tablet |
| Treatment | Blood cancer (Chronic myeloid leukaemia) |
Thioguanine 40 mg (6 TG) Tablets
Overview:
Thioguanine 40 mg (6 TG) Tablets contain Thioguanine, an antimetabolite chemotherapy medication. It is primarily used to treat acute leukemia by inhibiting DNA synthesis and cell division in cancer cells. Thioguanine is a purine analog that disrupts normal DNA and RNA function, leading to cancer cell death.
Indications:
- Acute Myelogenous Leukemia (AML): Used in combination with other chemotherapy agents for AML treatment.
- Chronic Myelogenous Leukemia (CML): Applied in cases where other treatments are ineffective.
Mechanism of Action:
Thioguanine is incorporated into the DNA of rapidly dividing cells and is converted into 6-thioguanine nucleotide. This compound interferes with purine nucleotide synthesis, disrupting DNA replication and RNA transcription, leading to cell death.
Dosage and Administration:
- Acute Leukemia: Typically 40 mg daily, often in combination with other chemotherapy drugs.
- CML: 40 mg daily, with possible dose adjustments based on response and tolerance.
- Administration: Take the tablet whole, with or without food. Do not crush or chew. Ensure adequate hydration.
Side Effects:
- Common: Nausea, vomiting, fatigue, bone marrow suppression, liver toxicity.
- Serious: Infections (due to immunosuppression), liver failure, severe bone marrow suppression, gastrointestinal bleeding.
- Monitor: Regular blood tests for liver function, blood cell counts, and bone marrow suppression are needed.
Precautions:
- Bone Marrow Suppression: Monitor blood counts regularly for anemia, thrombocytopenia, and leukopenia.
- Liver Dysfunction: Monitor liver function, especially in patients with preexisting liver disease.
- Pregnancy and Lactation: Contraindicated during pregnancy due to teratogenic effects; avoid during breastfeeding.
Storage:
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Thioguanine 40 mg (6 TG) Tablets effectively treat AML and CML by inhibiting DNA synthesis and inducing cell death. Regular monitoring for side effects such as bone marrow suppression and liver toxicity is essential during treatment.
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Lapatinib Herlapsa 250 mg Tablet
Product Price: Rs 4,800 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Packaging Size | 250 mg |
| Pack Size | 30 Tablets |
| Composition | Lapatinib 250 mg |
| Packaging Type | 30 Tablets In 1 Bottle |
| Brand Name | Herlapsa Tablet |
| Manufacturer | Mylan pharmaceutical Pvt. Ltd |
| Treatment | Breast Cancer |
Lapatinib (Herlapsa 250mg Tablet)
Overview:
Lapatinib (Herlapsa 250mg Tablet) is an oral targeted therapy used in the treatment of specific types of breast cancer, particularly in combination with other medications. It is a tyrosine kinase inhibitor that blocks the action of epidermal growth factor receptors (EGFR) and HER2 (human epidermal growth factor receptor 2) proteins, both of which promote the growth of cancer cells. By inhibiting these receptors, Lapatinib slows the growth and spread of cancer.
Indications:
Lapatinib 250mg Tablet is indicated for:
- HER2-positive breast cancer: In combination with capecitabine for patients with metastatic breast cancer that is HER2-positive.
- Advanced or metastatic breast cancer: In combination with letrozole for postmenopausal women who have hormone receptor-positive breast cancer.
Mechanism of Action:
Lapatinib works by inhibiting the activity of both EGFR and HER2 receptors, which are involved in cancer cell growth and proliferation. By blocking these receptors, Lapatinib reduces tumor cell growth, potentially leading to reduced tumor size and preventing further cancer spread.
Dosage and Administration:
- Recommended Dose: The usual dose is 1250mg once daily orally, taken with or without food.
- Administration: Swallow tablets whole with a glass of water. Do not chew, crush, or split the tablet.
- Missed Dose: If a dose is missed, take it as soon as possible, unless it is nearly time for the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Diarrhea
- Skin rashes or acne-like reactions
- Fatigue
- Nausea and vomiting
- Decreased appetite Serious side effects may include:
- Liver toxicity: Monitoring liver function is essential during treatment.
- Heart issues: Can cause heart failure or changes in heart rhythm.
- Severe allergic reactions: Rare but may include swelling, difficulty breathing, or skin rashes.
Precautions:
- Liver function: Regular liver enzyme tests are needed.
- Heart conditions: Patients with heart disease should be closely monitored during treatment.
- Pregnancy: Contraindicated during pregnancy as it may harm the fetus.
Storage:
Store Lapatinib tablets at room temperature (20°C to 25°C), away from heat and moisture. Keep out of reach of children.
Conclusion:
Lapatinib (Herlapsa 250mg Tablet) is an effective treatment for HER2-positive breast cancer and is usually prescribed in combination with other chemotherapy agents. Regular monitoring for liver function and heart health is crucial to ensure safety during treatment.
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Trifuridine Tipiracil Tipanat 15 mg/6.14 mg
Product Price: Rs 5,000 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 15 mg/ 6.14 mg |
| Brand | Tipanat |
| Packaging Size | 20 Tablets in 1 Bottle |
| Dose/Strength | 15 mg/6.14 mg |
| Composition | Trifluridine And Tipiracil 15 mg/6.14 mg |
| Brand Name | Tipanat 15 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Metastatic Colorectal Cancer |
Trifuridine Tipiracil (Tipanat 15mg/16.4mg)
Overview: Trifuridine Tipiracil (Tipanat 15mg/16.4mg) is an oral combination medication used to treat metastatic colorectal cancer. It contains two active ingredients: trifuridine, a nucleoside analogue, and tipiracil, a thymidine phosphorylase inhibitor. This combination works synergistically to block cancer cell division by interfering with DNA replication. Trifuridine is incorporated into the DNA of cancer cells, causing DNA damage and preventing cell proliferation. Tipiracil inhibits the breakdown of trifuridine, enhancing its effects.
Indications: Tipanat is indicated for the treatment of metastatic colorectal cancer (CRC) in patients who have previously been treated with other chemotherapy options, such as fluoropyrimidines, oxaliplatin, and irinotecan, or for patients who are intolerant to these therapies. It is used to manage advanced stages of CRC, helping to slow tumor progression and improve patient outcomes.
Mechanism of Action:
- Trifuridine: Once inside cancer cells, trifuridine is converted into active metabolites, which then become incorporated into DNA during replication, leading to DNA damage and triggering cell death.
- Tipiracil: By inhibiting thymidine phosphorylase, tipiracil prevents the premature breakdown of trifuridine, thereby increasing its bioavailability and ensuring its continued action against cancer cells.
Dosage and Administration:
- Recommended Dose: The usual dose is 35 mg/m² twice daily, taken with food on days 1 through 5 and days 8 through 12 of a 28-day treatment cycle. The dose may be adjusted depending on side effects and patient tolerance.
- Administration: Tipanat should be taken orally, with food, and tablets should be swallowed whole without crushing or chewing.
Side Effects: Common side effects include:
- Nausea, vomiting
- Fatigue
- Loss of appetite
- Diarrhea Serious side effects may include:
- Bone marrow suppression: Leading to anemia, neutropenia, and thrombocytopenia.
- Liver toxicity: Monitor liver function during treatment.
- Severe gastrointestinal issues: Including severe nausea and diarrhea.
Precautions:
- Bone Marrow Suppression: Regular monitoring of blood counts is essential.
- Pregnancy: Should not be used during pregnancy due to potential harm to the fetus.
- Liver function: Use with caution in patients with liver impairment.
Storage: Store Tipanat tablets at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion: Trifuridine Tipiracil (Tipanat 15mg/16.4mg) is an effective chemotherapy option for metastatic colorectal cancer, especially for patients who have failed prior treatments. Regular monitoring for side effects and liver function is necessary to ensure treatment safety.
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Imatinib Imatirel 400mg Tablet
Product Price: Rs 5,000 / BoxGet Best Price
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Product Details:
| Strength | 400 mg |
| Brand | Imatirel |
| Active Drug | Imatinib Mesylate |
| Packaging Type | 10 Tablet in 1 Strip |
| Composition | Imatinib 400 mg |
| Brand Name | Imatirel 400 mg |
| Manufacturer | Reliance Life Sciences Pvt Ltd |
| Treatment | Cancer |
Overview: 400mg Imatinib Tablet contains Imatinib, a tyrosine kinase inhibitor used to treat various cancers, including chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs), and Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Imatinib works by inhibiting abnormal proteins produced by cancer cells, specifically targeting the BCR-ABL fusion protein in CML, and other tyrosine kinases that drive tumor growth.
Indications: Imatinib 400mg Tablet is indicated for:
- Chronic Myelogenous Leukemia (CML): Treatment of Ph+ CML in chronic phase.
- Gastrointestinal Stromal Tumors (GISTs): Treatment of adult patients with unresectable or metastatic GISTs.
- Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL).
- Hypereosinophilic Syndrome and Chronic Eosinophilic Leukemia.
Mechanism of Action: Imatinib inhibits the BCR-ABL tyrosine kinase (produced by the Philadelphia chromosome in CML), along with other tyrosine kinases such as c-Kit (in GISTs) and PDGFR (platelet-derived growth factor receptor). By blocking these abnormal signaling pathways, Imatinib prevents tumor growth and induces cell death.
Dosage and Administration:
- CML (Chronic Phase): 400mg orally once daily.
- GIST: 400mg orally once daily.
- Ph+ ALL: Typically 600mg orally daily for induction, then reduced to 400mg daily for maintenance.
Imatinib should be taken with food and a glass of water to reduce the risk of gastrointestinal irritation.
Side Effects: Common side effects include:
- Edema, fatigue, nausea, muscle cramps, and rash.
- Bone marrow suppression: Neutropenia, thrombocytopenia, and anemia.
- Liver enzyme elevation, diarrhea, and headache.
Serious side effects may include:
- Severe liver toxicity, heart failure, and fluid retention.
- Tumor lysis syndrome, gastrointestinal bleeding, and bleeding complications.
Precautions:
- Blood counts: Regular monitoring of blood counts due to the risk of myelosuppression.
- Liver function: Regular liver function tests to detect hepatotoxicity.
- Heart conditions: Use with caution in patients with heart failure or fluid retention.
- Pregnancy: Imatinib is contraindicated during pregnancy due to potential harm to the fetus.
Storage: Store Imatinib tablets at room temperature (20°C to 25°C), away from moisture and light. Keep out of reach of children.
Conclusion: 400mg Imatinib Tablet is an effective targeted therapy for CML, GISTs, and Ph+ ALL, significantly improving patient outcomes by inhibiting the molecular drivers of cancer growth. Regular monitoring of blood counts, liver function, and cardiovascular health is essential for safe use.
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Imatinib Tablet (Imat 400 mg Tablets)
Product Price: Rs 2,000 / StripGet Best Price
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Product Details:
| Strength | 400 mg |
| Brand | Imat |
| Active Drug | Imatinib Mesylate |
| Pack Size | 10 Tablets in 1 Strip |
| Compsotion | Imatinib mesylate 400 mg |
| Brand Name | Imat 400 mg Tablets |
| Manufacturer | Zydus Healthcare Limited |
| Treatment | Cancer |
Imatinib Tablet (Imat 400 mg Tablets)
Overview:
Imatinib, marketed under the brand name Imat 400 mg Tablets, is a tyrosine kinase inhibitor used in the treatment of certain types of cancer. It works by inhibiting specific enzymes that contribute to the growth of cancer cells. Imatinib is primarily used in the treatment of chronic myelogenous leukemia (CML), acute lymphoblastic leukemia (ALL), gastrointestinal stromal tumors (GISTs), and other rare cancers. It targets the BCR-ABL protein that causes abnormal cell growth in CML, and it also inhibits other tyrosine kinases involved in tumor growth.
Indications:
Imatinib 400 mg is indicated for:
- Chronic Myelogenous Leukemia (CML): For newly diagnosed and resistant cases.
- Acute Lymphoblastic Leukemia (ALL): For Philadelphia chromosome-positive cases.
- Gastrointestinal Stromal Tumors (GISTs): For treatment of unresectable or metastatic GISTs.
- Other cancers: Imatinib is also used for myelodysplastic/myeloproliferative diseases, hypereosinophilic syndrome, and systemic mastocytosis.
Mechanism of Action:
Imatinib specifically targets and inhibits the activity of BCR-ABL tyrosine kinase, an abnormal enzyme produced by the Philadelphia chromosome in CML. By blocking this enzyme, Imatinib prevents the activation of downstream pathways that would normally promote the proliferation of cancer cells. Imatinib also inhibits KIT, PDGFRA, and other tyrosine kinases involved in tumor growth.
Dosage and Administration:
- Recommended Dose: The typical dose for adults is 400 mg once daily for CML, though the dose may be adjusted based on the patient's response or side effects.
- Administration: Imatinib should be taken with food and a full glass of water to minimize gastrointestinal irritation. Tablets should be swallowed whole; do not chew or crush.
- Missed Dose: If a dose is missed, take it as soon as possible unless it is close to the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Nausea, vomiting
- Fatigue
- Edema (swelling)
- Muscle cramps
- Headache Serious side effects include:
- Cardiovascular issues: Edema, heart failure.
- Hepatotoxicity: Liver function may be affected.
- Myelosuppression: Decreased blood cell counts.
Precautions:
- Liver and kidney function: Liver function tests should be monitored.
- Pregnancy: Should be used only when necessary as it can harm the fetus.
- Cytopenia: Monitor blood cell counts regularly.
Storage:
Store Imatinib tablets at room temperature (20°C to 25°C), in a dry place, away from moisture and light. Keep out of reach of children.
Conclusion:
Imatinib 400 mg tablets are an essential treatment for several cancers, particularly CML and GISTs. Monitoring for side effects such as liver toxicity and blood cell counts is important to ensure patient safety and treatment effectiveness.
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Thioguanine 40 mg Tablets
Product Price: Rs 180 / StripGet Best Price
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Product Details:
| Strength | 40 mg |
| Composition | Thioguanine 40 mg |
| Brand Name | 6 TG 40 mg Tablet |
| Packaging Size | 10 Tablets in 1 Strip |
| Manufacturer | Miracalus Pharma Ltd |
| Treatment | Blood cancer |
| Dose/Strength | 40 mg |
40 mg Thioguanine Tablets
Overview:Thioguanine 40 mg Tablets are an oral chemotherapy medication containing Thioguanine, a purine analog used in the treatment of certain types of cancer, including acute leukemia. Thioguanine is classified as an antimetabolite and works by interfering with the synthesis of DNA in cancer cells. By incorporating into the DNA structure, Thioguanine disrupts the normal replication and function of DNA, leading to cell death. It is typically used in combination with other chemotherapeutic agents as part of a combination chemotherapy regimen.
Indications:Thioguanine 40 mg Tablets are indicated for:
- Acute Myelogenous Leukemia (AML): As part of combination therapy for patients with AML, especially in the maintenance phase or for patients who cannot tolerate other therapies.
- Chronic Myelogenous Leukemia (CML): In patients who have failed previous therapies or are intolerant to other treatments.
- Other Leukemias: Sometimes used off-label in the treatment of other hematologic cancers.
Thioguanine is a purine analog, similar to the natural purines adenine and guanine. Once inside the body, Thioguanine is converted into its active metabolites, thioguanine nucleotides. These metabolites are incorporated into the DNA and RNA of cancer cells, disrupting their normal function. This inhibits DNA replication and cell division, which is particularly effective in rapidly dividing cells such as leukemia cells. By inhibiting purine metabolism, Thioguanine prevents cancer cells from multiplying, thus slowing or halting tumor growth.
Dosage and Administration:- Recommended Dose: 40 mg once daily for most adults, taken orally. The dosage may vary depending on the patient's specific condition, and adjustments may be necessary based on tolerance and blood counts.
- Administration: Swallow the tablet whole with a glass of water. It can be taken with or without food. Ensure regular blood monitoring during treatment to assess for side effects and adjust the dosage accordingly.
- Common Side Effects: Nausea, vomiting, diarrhea, loss of appetite, and bone marrow suppression, which may lead to anemia, leukopenia, or thrombocytopenia.
- Serious Side Effects: Liver toxicity, pancreatitis, gastrointestinal bleeding, and infections due to low white blood cell counts. Regular monitoring of liver function, blood counts, and overall health is essential during therapy.
- Bone Marrow Suppression: Thioguanine can cause significant myelosuppression, so blood cell counts must be monitored regularly.
- Liver Function: Monitor for signs of liver toxicity, as Thioguanine can cause liver damage. Liver function tests should be performed during treatment.
- Pregnancy and Lactation: Thioguanine is contraindicated during pregnancy and breastfeeding. Effective contraception should be used during treatment.
Store Thioguanine 40 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep the medication out of reach of children.
Conclusion:Thioguanine 40 mg Tablets are an essential treatment for acute leukemia and other hematologic cancers. By interfering with DNA synthesis, Thioguanine helps to slow or stop the growth of cancer cells. Regular monitoring of blood counts, liver function, and overall health is crucial for managing potential side effects and ensuring the safety and effectiveness of the treatment.
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200mg Sorafenat Sorafenib Tosylate Tablet
Product Price: Rs 4,350 / BottleGet Best Price
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Product Details:
| Packaging Size | 120 Tablets |
| Strength | 200 mg |
| Form | Tablet |
| Brand | Natco |
| Pack Type | Box |
| Usage | Used To Treat Kidney Cancer |
Overview:
Sorafenat 200 mg Tablets contain Sorafenib, an oral multi-kinase inhibitor used in the treatment of various cancers. Sorafenib works by inhibiting the activity of several kinases involved in the growth of cancer cells and the formation of blood vessels that supply tumors (angiogenesis). It blocks signaling pathways that promote tumor growth, including Raf kinase and vascular endothelial growth factor receptor (VEGFR).
- Hepatocellular Carcinoma (HCC): For the treatment of advanced liver cancer (hepatocellular carcinoma) that cannot be surgically removed or has spread.
- Renal Cell Carcinoma (RCC): For advanced renal cell carcinoma (kidney cancer), typically in combination with other therapies.
- Differentiated Thyroid Cancer: For progressive, metastatic differentiated thyroid cancer that is refractory to radioactive iodine treatment.
- Other Cancers: Sorafenib is sometimes used off-label for other cancers, including soft tissue sarcomas and bladder cancer.
Sorafenib is a tyrosine kinase inhibitor (TKI) that targets multiple receptors involved in tumor growth and angiogenesis. It inhibits Raf kinase (a key driver in cell growth), VEGFR, PDGFR, and other kinases involved in tumor blood vessel formation. This multi-targeted action results in tumor growth inhibition and reduced metastasis.
Dosage and Administration:- Hepatocellular Carcinoma (HCC): The recommended dose is 400 mg twice daily (morning and evening) for as long as the patient tolerates the drug.
- Renal Cell Carcinoma (RCC): The standard dose is 400 mg twice daily, taken continuously until disease progression or unacceptable toxicity occurs.
- Differentiated Thyroid Cancer: The dose is usually 400 mg twice daily.
- Administration: Take orally with or without food. Swallow tablets whole with water. Do not crush or chew the tablets.
Common: Diarrhea, fatigue, rash, high blood pressure, nausea, loss of appetite, and hand-foot skin reaction (redness, swelling, pain).
Serious: Liver toxicity, severe bleeding, heart problems, hypertension, and hand-foot syndrome.
Monitor: Regular liver function tests, blood pressure monitoring, and skin assessments are recommended.
- Liver Function: Use with caution in patients with liver disease or liver dysfunction. Regular monitoring of liver enzymes is required.
- Hypertension: Sorafenib may increase blood pressure; monitor regularly and treat accordingly.
- Bleeding Risk: Sorafenib can increase the risk of severe bleeding. Caution is required in patients with a history of bleeding disorders.
- Pregnancy and Lactation: Contraindicated during pregnancy due to potential fetal harm. Avoid breastfeeding while on treatment.
Store Sorafenat 200 mg Tablets at room temperature (15°C to 30°C) in a dry place, away from light and moisture. Keep out of reach of children.
Conclusion:Sorafenat 200 mg Tablets (Sorafenib) is an oral multi-kinase inhibitor used in the treatment of advanced liver cancer, renal cell carcinoma, and thyroid cancer. By targeting multiple pathways involved in tumor growth and blood vessel formation, Sorafenib helps to slow down cancer progression. Regular monitoring for liver function, blood pressure, and skin reactions is essential during treatment.
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Imatinib (Imatib 400 Tablet)
Product Price: Rs 750 / StripeGet Best Price
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Product Details:
| Strength | 400 mg |
| Form | Tablet |
| Prescription/Non prescription | Prescription |
| Brand | Imatib |
| Packaging Type | Box |
| Manufactured by | Cipla |
| Medicine brand | Imatib 400 |
| Medicine form | Tablet |
| Medicine name | imatinib tablets ip 400 mg |
| Medicine strength | 400 mg |
| Packaging size | 10 tablets |
| Salt composition | Imatinib |
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Invista Dasatinib 70 mg Tablets
Product Price: Rs 2,000 / BoxGet Best Price
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Product Details:
| Strength | 70 mg |
| Pack Size | 1*10 Tablet |
| Composition | Dasatinib 70 mg |
| Brand | Invista 70 mg |
| Manufactured By | Dr Reddy'S Laboratories Ltd |
| Treatment | Cancer/Oncology |
Invista Dasatinib 70 mg Tablets
Overview:
Invista (Dasatinib) is an oral tyrosine kinase inhibitor used in the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) and acute lymphoblastic leukemia (Ph+ ALL). It works by inhibiting the BCR-ABL1 tyrosine kinase, a protein that promotes cancer cell growth. By blocking this and other kinases, Invista slows the progression of leukemia and induces cancer cell death.
Indications:
Invista 70 mg is used for:
- Chronic Myelogenous Leukemia (CML): For patients with Ph+ CML in chronic, accelerated, or blast phase.
- Acute Lymphoblastic Leukemia (ALL): For Ph+ ALL, especially in patients resistant to other treatments.
- Other cancers: Sometimes used for additional hematological cancers under specialized protocols.
Mechanism of Action:
Dasatinib targets and blocks the BCR-ABL1 tyrosine kinase, a critical enzyme that causes uncontrolled leukemia cell growth. By inhibiting this enzyme, Dasatinib also affects other kinases, stopping cancer cell division and promoting cell death.
Dosage and Administration:
- Ph+ CML: The typical dose is 100 mg once daily for the chronic phase, and 140 mg once daily for accelerated or blast phase.
- Ph+ ALL: The recommended dose is 70 mg twice daily.
- Administration: Take on an empty stomach (at least 1 hour before or 2 hours after meals). Swallow whole; do not crush or chew.
- Missed dose: If a dose is missed, take it as soon as possible unless close to the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Fatigue
- Nausea
- Headache
- Rash
- Muscle pain
Serious side effects may include:
- Pulmonary arterial hypertension (PAH): A rare but serious lung condition.
- Bleeding: Increased risk of bleeding or bruising.
- Liver toxicity: Elevated liver enzymes.
- Fluid retention: Swelling in legs, ankles, or eyes.
- Cardiac issues: QT prolongation, arrhythmias.
Precautions:
- Pregnancy and breastfeeding: Should not be used during pregnancy or breastfeeding due to risks to the baby.
- Liver function: Regular liver enzyme tests are required.
- Heart conditions: Caution with QT prolongation. Patients with heart issues should be monitored.
- Drug interactions: Can interact with CYP3A4 inhibitors. Inform your doctor of all medications.
Monitoring:
- Blood counts: Regular CBC to check for bone marrow suppression.
- Liver function: Monitor liver enzyme levels.
- Heart function: Monitor for QT prolongation and other cardiac issues.
Storage:
Store Invista at room temperature (15°C to 30°C or 59°F to 86°F), in a dry place, away from heat and moisture. Keep out of reach of children.
Patient Counseling:
- Adherence: Take the medication as prescribed. Do not skip doses.
- Side effects: Report any unusual bleeding, difficulty breathing, or swelling.
- Hydration: Drink plenty of fluids to help manage side effects.
Conclusion:
Invista (Dasatinib) 70 mg Tablets is a potent treatment for Ph+ CML and Ph+ ALL, blocking critical cancer-related enzymes. Adherence to dosing, regular monitoring, and immediate reporting of side effects are essential for maximizing treatment benefits.
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Spnib Dasatinib 100mg Tablet
Product Price: Rs 2,500 / BottleGet Best Price
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Product Details:
| Strength | 100 mg |
| Pack Size | 1*30 Tablet |
| Composition | Dasatinib 100 mg |
| Brand | Spnib 100 mg |
| Manufactured By | Zydus Cadila |
| Treatment | Philadelphia Chromosome-positive Chronic Myeloid Leukemia And Philadelphia Chromosome-positive Acute |
Spnib (Dasatinib) 100mg Tablet
Overview:
Spnib (Dasatinib) is an oral medication used in the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (CML) and acute lymphoblastic leukemia (ALL). It is a tyrosine kinase inhibitor (TKI) that blocks certain enzymes (such as BCR-ABL1 tyrosine kinase) involved in cancer cell growth, thereby slowing or halting the progression of leukemia.
Indications:
Spnib 100mg is indicated for:
- Chronic Myelogenous Leukemia (CML): In patients with Ph+ CML, particularly in the chronic, accelerated, or blast phases.
- Acute Lymphoblastic Leukemia (ALL): Specifically for Ph+ ALL in adult and pediatric patients who have not responded to other treatments.
- Other uses: Occasionally used in other hematological cancers under specialized care.
Mechanism of Action:
Dasatinib inhibits BCR-ABL1 tyrosine kinase, a key protein that drives cancer cell proliferation in Ph+ CML and ALL. By blocking this enzyme and related kinases, Spnib prevents the growth of cancer cells and promotes their death, helping to control the leukemia.
Dosage and Administration:
- Recommended dose: For CML, 100 mg once daily for chronic phase or 140 mg once daily for accelerated/blast phase. For Ph+ ALL, 70 mg twice daily.
- Administration: Take on an empty stomach, at least 1 hour before or 2 hours after meals. Swallow whole; do not crush or chew tablets.
- Missed dose: If a dose is missed, take it as soon as possible unless it's near the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Headache
- Fatigue
- Nausea
- Rash
- Muscle pain
Serious side effects may include:
- Pulmonary arterial hypertension (PAH), bleeding, liver problems (elevated liver enzymes), fluid retention, and heart issues (QT prolongation, arrhythmias).
Precautions:
- Pregnancy and breastfeeding: Not recommended during pregnancy or breastfeeding. Dasatinib can harm an unborn baby.
- Liver function: Monitor liver enzymes regularly to detect liver toxicity.
- Heart issues: Caution in patients with heart disease as Dasatinib can cause QT interval prolongation.
- Drug interactions: Dasatinib can interact with drugs that affect CYP3A4 enzymes. Inform your healthcare provider about all medications being taken.
Monitoring:
- Blood counts: Regular CBC to monitor bone marrow suppression (low blood counts).
- Liver function: Regular tests for liver enzymes to detect potential liver damage.
- Heart function: Monitor for signs of QT prolongation or heart problems.
Storage:
Store Spnib at room temperature (15°C to 30°C or 59°F to 86°F) in a dry place, away from heat and moisture. Keep out of reach of children.
Patient Counseling:
- Adherence: Take the medication exactly as prescribed. Do not skip doses.
- Side effects: Report any signs of bleeding, breathing difficulty, or swelling.
- Hydration: Drink plenty of fluids to help manage side effects.
Conclusion:
Spnib (Dasatinib) 100mg tablet is an effective treatment for Ph+ CML and Ph+ ALL, helping to slow cancer cell growth. Regular monitoring and adherence to the prescribed regimen are crucial for maximizing treatment benefits and minimizing side effects.
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Geftinat Tablet (Gefitinib 250 mg)
Product Price: Rs 3,000 / StripGet Best Price
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Product Details:
| Strength | 250 mg |
| Pack Size | 30 Tablets in 1 Strip |
| Composition | Gefitinib 250 mg |
| Brand Name | Geftinat 250 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Non-small Cell Lung Cancer |
Geftinat Tablet (Gefitinib 250 mg)
Overview:Geftinat 250 mg Tablets contain Gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) used in the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations. Gefitinib targets and blocks the EGFR receptor, which is involved in the growth and spread of cancer cells. By inhibiting EGFR, Gefitinib helps slow down the proliferation of cancer cells, reducing tumor size and improving patient survival rates. It is typically used in patients with advanced or metastatic NSCLC who have specific EGFR mutations.
Indications:Geftinat 250 mg Tablets are indicated for:
- Non-Small Cell Lung Cancer (NSCLC): For the treatment of locally advanced or metastatic NSCLC in adults whose tumors have specific EGFR mutations (exon 19 deletions or exon 21 L858R substitution) as detected by an approved diagnostic test.
- First-Line Treatment: For patients with EGFR mutation-positive NSCLC who have not received prior chemotherapy.
Gefitinib works by inhibiting the EGFR tyrosine kinase enzyme, a receptor that, when activated, triggers the growth and division of cancer cells. In NSCLC, mutations in the EGFR gene lead to uncontrolled cell growth. Gefitinib binds to the EGFR, preventing the receptor from activating the intracellular signaling pathways that drive cancer cell proliferation. This results in the inhibition of tumor growth and spread.
Dosage and Administration:- Recommended Dose: The usual dose of Geftinat 250 mg is one tablet once daily.
- Administration: The tablet can be taken with or without food. It should be swallowed whole with a glass of water. It is important to take the medication at the same time each day to maintain steady blood levels.
- Common Side Effects: Diarrhea, acneiform rash, nausea, loss of appetite, and fatigue.
- Serious Side Effects: Interstitial lung disease (ILD), hepatotoxicity, eye problems (e.g., dry eye, irritation), and gastrointestinal perforation. Liver function and lung symptoms should be monitored during treatment.
- Lung Disease: Use caution in patients with a history of lung disease, as Gefitinib may cause or worsen interstitial lung disease (ILD).
- Liver Disease: Patients with liver problems should be monitored closely, as Gefitinib can cause liver toxicity (elevated liver enzymes).
- Pregnancy: Gefitinib is Category D (may harm the fetus). It should be avoided during pregnancy unless the potential benefit justifies the risk.
- Drug Interactions: Gefitinib may interact with drugs that affect the CYP3A4 enzyme, which is involved in its metabolism. Consult your healthcare provider about other medications.
Store Geftinat 250 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Geftinat 250 mg Tablets are a targeted therapy for patients with EGFR mutation-positive non-small cell lung cancer. When used appropriately, Gefitinib helps inhibit tumor growth and improve outcomes in advanced lung cancer. Regular monitoring for side effects, particularly lung and liver function, is essential for safe and effective treatment.
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Apatinib Mesylate Tablets
Product Price: Rs 500 / BoxGet Best Price
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Product Details:
| Strength | 0.25g |
| Packaging Size | 30 Tablet in 1 Box |
| Composition | Apatinib mesylate tablet |
| Brand | Apatinib tablets |
| Manufacturer | Jiangsu Hengrui Pharmaceutical |
| Treatment | Advanced liver cancer |
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Glivec Imatinib 100 mg Tablets
Product Price: Rs 650 / StripeGet Best Price
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Product Details:
| Strength | 100 mg |
| Form | Tablet |
| Prescription/Non prescription | Prescription |
| Packaging Type | Box |
| Packaging Size | 5x10 Tab |
| Medicine brand | Glivec |
| Medicine form | Tablet |
| Medicine name | Imatinib mesylate tablets ip |
| Medicine strength | 100 mg |
| Packaging size | 6x10 |
| Packaging type | Box |
| Salt composition | Imatinib mesylate |
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Bqnat 100mg Tablet
Product Price: Rs 16,450 / BoxGet Best Price
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Product Details:
| Dose/Strength | 100 mg |
| Brand | Bqnat |
| Strength | 100 mg |
| Packaging Size | 188 Tablet Per Bottle |
| Manufacturer | Natco Pharma Ltd |
| Composition | Bedaquiline 100 mg |
| Treatment | Multidrug-resistant pulmonary tuberculosis (MDR-TB) in adults. |
Bqnat (Baclofen 100 mg Tablet) is a powerful muscle relaxant commonly used to treat muscle spasticity associated with neurological conditions. If you’re searching for effective relief from muscle stiffness and spasms, Bqnat offers a reliable solution to enhance your quality of life.
What is Bqnat?Bqnat contains Baclofen, a medication that acts on the central nervous system to relieve muscle spasticity. It is particularly beneficial for individuals suffering from conditions such as multiple sclerosis, spinal cord injuries, or other neurological disorders.
IndicationsBqnat is indicated for:
- Muscle Spasticity: Helps alleviate symptoms related to conditions like multiple sclerosis and spinal cord injuries.
- Neuropathic Pain: May provide relief from pain caused by nerve damage.
Baclofen works as a GABA-B receptor agonist. By enhancing the inhibitory effects of GABA, it reduces the excitability of neurons, leading to decreased muscle tone and spasticity. This mechanism helps improve movement and reduce discomfort.
Dosage and Administration- Dosage: The typical starting dose is 5 mg, which may be increased gradually based on the patient's response, up to a maximum of 100 mg per day in divided doses.
- Administration: Bqnat should be taken orally with or without food. It's essential to follow the prescribed dosage from your healthcare provider.
Bqnat is contraindicated in:
- Hypersensitivity: Known allergy to Baclofen or any components of the formulation.
- Severe Renal Impairment: Caution is advised in patients with significant kidney issues.
- Withdrawal Symptoms: Sudden discontinuation can lead to withdrawal symptoms. Gradual tapering of the dose is recommended.
- CNS Depression: Use with caution in patients with a history of seizures or other central nervous system disorders.
- Alcohol Interaction: Avoid alcohol while taking Bqnat, as it can enhance drowsiness and dizziness.
Common side effects may include:
- Drowsiness
- Dizziness
- Fatigue
- Nausea
Serious side effects can include:
- Severe allergic reactions (anaphylaxis)
- Confusion or hallucinations
- Respiratory depression
Bqnat may interact with other CNS depressants, such as opioids and alcohol. Always inform your healthcare provider about all medications and supplements you are taking.
Storage InstructionsStore Bqnat (Baclofen 100 mg Tablet) at room temperature, away from moisture and direct sunlight. Keep out of reach of children.
Patient Counseling Information- Advise patients to take Bqnat exactly as prescribed and not to alter the dosage without consulting their healthcare provider.
- Discuss potential side effects and the importance of reporting any severe symptoms.
- Encourage regular follow-up appointments to monitor treatment efficacy and side effects.
Bqnat (Baclofen 100 mg Tablet) is an effective treatment for muscle spasticity and related conditions. Its muscle-relaxing properties can significantly enhance mobility and comfort for those affected by neurological disorders.
Call to ActionIf you or a loved one are experiencing muscle spasticity, consult your healthcare provider about Bqnat and discover how it can help improve your daily life.
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10mg Xarelto Rivaroxaban Tablet
Product Price: Rs 500 / BoxGet Best Price
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Product Details:
| Strength | 10 mg |
| Pack Size | 10 tablets |
| Brand | Bayer |
| Packaging Size | 10 Tablets |
| Form | Tablet |
| Usage | Used To Treat Blood Clots |
Xarelto 10mg Tablet is a medicine known as an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain and heart.
Xarelto 10mg Tablet is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It should be taken with food and it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
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60 mg Pryor Apalutamide Tablet
Product Price: Rs 25,000 / PieceGet Best Price
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Product Details:
| Strength | 60 mg |
| Brand | Pryor |
| Pack Size | 120 Tablets |
| Compostion | Apalutimide |
| Brand Name | Pryor 60 mg |
| Manufacturer | Zydus |
| Treatment | Metastatic Castration-sensitive Prostate Cancer |
Overview:
Pryor 60 mg Tablets contain Apalutamide, an androgen receptor inhibitor used in the treatment of prostate cancer. Apalutamide works by blocking the action of androgens (male hormones like testosterone) on prostate cancer cells, which can inhibit cancer cell growth. It is used primarily for the treatment of metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer.
- Metastatic Castration-Sensitive Prostate Cancer: In combination with androgen deprivation therapy (ADT), for the treatment of metastatic prostate cancer that is still responsive to hormone therapy.
- Non-Metastatic Castration-Resistant Prostate Cancer (nmCRPC): For patients with prostate cancer that has progressed despite low testosterone levels but has not yet spread to other parts of the body.
Apalutamide is a non-steroidal anti-androgen that works by binding to the androgen receptor on prostate cancer cells, blocking the effect of androgens (like testosterone). This inhibition prevents the receptor from activating gene expression that promotes tumor growth and survival. By depriving prostate cancer cells of androgen signaling, Apalutamide slows down or stops the progression of the disease.
Dosage and Administration:- Metastatic Castration-Sensitive Prostate Cancer: The recommended dose is 240 mg (four 60 mg tablets) once daily, in combination with androgen deprivation therapy (ADT).
- Non-Metastatic Castration-Resistant Prostate Cancer: The recommended dose is 240 mg once daily.
- Administration: Take the tablet orally, with or without food. Do not crush or chew the tablet. Swallow the tablet whole with a glass of water.
Common: Fatigue, hot flashes, rash, diarrhea, and weight loss.
Serious: Seizures, liver toxicity, cardiovascular issues (e.g., high blood pressure, heart disease), and allergic reactions (e.g., swelling, breathing difficulty).
Monitor: Regular monitoring of liver function, blood pressure, and for signs of seizures is advised during treatment.
- Seizures: Apalutamide may increase the risk of seizures, so use with caution in patients with a history of seizures or other neurological disorders.
- Liver Function: Apalutamide can affect liver function, so liver enzyme levels should be regularly monitored.
- Cardiovascular Health: Apalutamide can increase blood pressure and may affect heart function. Monitoring of blood pressure and cardiovascular health is essential.
- Pregnancy and Lactation: Contraindicated during pregnancy. Apalutamide can harm the fetus and should not be used by women who are pregnant or breastfeeding.
Store Pryor 60 mg Tablets at room temperature (15°C to 30°C), in a dry place away from light and moisture. Keep out of reach of children.
Conclusion:Pryor 60 mg Tablets (Apalutamide) is an effective treatment for metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. By blocking androgen receptors, Apalutamide inhibits the growth and survival of prostate cancer cells. Regular monitoring of liver function, blood pressure, and seizure activity is essential during treatment to manage potential side effects.
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50mg Ablu Bicalutamide Tablet
Product Price: Rs 150 / PackGet Best Price
Minimum Order Quantity: 10 Pack
Product Brochure
Product Details:
| Composition | Bicalutamide |
| Brand Name | Ablu |
| Form | Tablet |
| Strength | 50mg |
| Brand | Neon |
| Pack Type | Box |
| Pack Size | 3x10 Tablet |
| Usage | Used To Treat Cancer |
| Shelf Life | 2 Years |
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50mg Ablu Bicalutamide Tablet
Overview:
Ablu 50mg Tablet contains Bicalutamide, a non-steroidal anti-androgen used in the treatment of prostate cancer. Bicalutamide works by blocking the action of androgens (male hormones) like testosterone that stimulate the growth of prostate cancer cells. By inhibiting the androgen receptors, Bicalutamide reduces the growth of cancer cells, particularly in metastatic prostate cancer.Indications:
Ablu 50mg Tablet is primarily indicated for:- Prostate Cancer: Treatment of locally advanced, metastatic, or hormone-dependent prostate cancer.
- Adjuvant Therapy: Often used in combination with LHRH agonists (luteinizing hormone-releasing hormone) as part of androgen deprivation therapy (ADT) in prostate cancer.
Mechanism of Action:
Bicalutamide acts by competitively binding to androgen receptors on prostate cancer cells, preventing testosterone and other androgens from activating these receptors. This reduces the ability of cancer cells to grow and divide. Unlike other treatments, Bicalutamide does not lower the production of testosterone but blocks its action at the receptor level.Dosage and Administration:
- Recommended Dose: The usual dose of Ablu 50mg is one tablet daily, taken orally at the same time each day. It is commonly administered in combination with LHRH agonists for enhanced efficacy.
- Administration: The tablet should be swallowed whole with water, with or without food. Do not chew, break, or crush the tablet.
- Monitoring: Regular monitoring of liver function and prostate-specific antigen (PSA) levels is recommended during treatment.
Side Effects:
Common side effects include:- Hot flashes, fatigue, and nausea.
- Gynecomastia (breast tenderness or enlargement) and reduced libido.
- Diarrhea and constipation.
Serious side effects may include:
- Liver toxicity: Bicalutamide can cause liver dysfunction, so liver function tests should be monitored regularly.
- Cardiovascular issues: Rarely, it can increase the risk of heart disease or lung toxicity.
Precautions:
- Liver function: Bicalutamide should be used with caution in patients with liver impairment. Regular liver function monitoring is necessary.
- Pregnancy and Breastfeeding: Bicalutamide is contraindicated during pregnancy and breastfeeding as it may harm the fetus or infant.
- Caution in pre-existing heart conditions: Patients with cardiovascular diseases should be monitored during treatment.
Storage:
Store Ablu 50mg Tablets at room temperature (20°C to 25°C), away from light, moisture, and heat.Conclusion:
Ablu 50mg Bicalutamide Tablets are an effective treatment for hormone-dependent prostate cancer. By blocking androgen receptors, Bicalutamide slows or halts cancer cell growth. Regular monitoring of liver function and PSA levels is crucial to ensure patient safety and treatment efficacy.
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Oncolet Letrozole 2.5 mg Tablet
Product Price: Rs 50 / StripGet Best Price
Product Brochure
Product Details:
| Strength | 2.5 mg |
| Dose/Strength | 2.5 mg |
| Brand | Oncolet |
| Tablets per Pack | 10 Tablets |
| Packaging Size | 10 Tablets In 1 Strip |
| Treatment | Breast Cancer |
| Composition | Letrozole 2.5 mg |
| Brand Name | Oncolet 2.5 mg Tablet |
| Manufacturer | Zydus Cadila |
Oncolet Letrozole 2.5 mg Tablet
Overview:Oncolet 2.5 mg Tablets contain Letrozole, a non-steroidal aromatase inhibitor used primarily in the treatment of hormone receptor-positive (HR+) breast cancer in postmenopausal women. Letrozole works by inhibiting the aromatase enzyme, which converts androgens (male hormones) into estrogens (female hormones). Since estrogen can fuel the growth of certain types of breast cancer, reducing estrogen levels helps slow or stop the growth of hormone-sensitive cancer cells.
Indications:Oncolet 2.5 mg Tablets are indicated for:
- Adjuvant Treatment of Early-Stage Breast Cancer: Used in postmenopausal women with HR+ early-stage breast cancer following surgery to reduce the risk of recurrence.
- Metastatic Breast Cancer: For the treatment of advanced HR+ breast cancer in postmenopausal women.
- Neoadjuvant Therapy: To shrink the tumor before surgery in postmenopausal women with HR+ breast cancer.
Letrozole inhibits the aromatase enzyme, which is involved in the conversion of androgens into estrogen. Estrogen stimulates the growth of hormone receptor-positive breast cancer cells. By reducing estrogen production, Oncolet helps to slow tumor growth and reduce the likelihood of cancer recurrence. This mechanism of action is particularly effective in postmenopausal women, where aromatase is the primary source of estrogen.
Dosage and Administration:- Recommended Dose: 2.5 mg once daily, taken orally with or without food.
- Administration: Swallow the tablet whole with a glass of water. It is important to take Oncolet at the same time each day for consistent blood levels.
- Common Side Effects: Hot flashes, joint pain, fatigue, nausea, headache, and mood swings.
- Serious Side Effects: Osteoporosis (bone thinning), cardiovascular problems, liver function abnormalities, and increased cholesterol. Regular monitoring for bone density and cardiovascular health is recommended.
- Bone Health: Prolonged use can lead to bone loss, so bone density should be monitored. Calcium and vitamin D supplementation may be needed.
- Cardiovascular Health: Women with existing heart disease should be carefully monitored for cardiovascular risks.
- Liver Function: Caution in patients with liver impairment, with regular liver function tests.
Store Oncolet 2.5 mg Tablets at room temperature (15°C to 30°C), away from moisture and light. Keep out of reach of children.
Conclusion:Oncolet (Letrozole 2.5 mg Tablets) is a key treatment for HR+ breast cancer in postmenopausal women. By reducing estrogen levels, it slows the growth of hormone-dependent breast cancer cells, offering a crucial option for patients in both early-stage and metastatic settings. Regular monitoring for bone health, cardiovascular risks, and liver function is important for safe and effective treatment.
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Letrozole Tablets(Letroheal 2.5 mg Tablets)
Product Price: Rs 200 / StripGet Best Price
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Product Details:
| Strength | 2.5 mg |
| Dose/Strength | 2.5 mg |
| Brand | Letroheal |
| Tablets per Pack | 10 Tablets |
| Packaging Size | 10 Tablets in 1 Strip |
| Composition | Letrozole 2.5 mg |
| Brand Name | Letroheal 2.5 mg tablets |
| Treatment | Breast cancer |
| Manufacturer | Healing Pharma India Pvt Ltd |
Letrozole 2.5mg Tablets (Letroheal)
Overview:
Letrozole (brand name: Letroheal) is an oral medication used primarily in the treatment of hormone-receptor-positive breast cancer in postmenopausal women. It is a nonsteroidal aromatase inhibitor that works by blocking the enzyme aromatase, which is responsible for converting androgens into estrogens. By reducing estrogen levels in the body, Letrozole helps to inhibit the growth of estrogen-dependent tumors, slowing or stopping the progression of cancer.
Indications:
Letroheal 2.5mg Tablets are used for:
- Adjuvant treatment of early-stage breast cancer in postmenopausal women.
- Treatment of hormone receptor-positive metastatic breast cancer in postmenopausal women.
- Prevention of breast cancer recurrence following surgery or radiation therapy.
Mechanism of Action:
Letrozole works by inhibiting the aromatase enzyme, which is responsible for the production of estrogen in the body. Lowering estrogen levels reduces the growth stimulus for estrogen-sensitive cancer cells. This action helps to prevent the recurrence of breast cancer and can shrink or stop the growth of existing tumors.
Dosage and Administration:
- Recommended Dose: The standard dosage is 2.5mg once daily, taken orally with or without food.
- Administration: Letrozole should be taken at the same time each day to maintain consistent blood levels.
- Missed Dose: If a dose is missed, take it as soon as remembered, unless it is nearly time for the next dose. Do not take a double dose to make up for the missed one.
Side Effects:
Common side effects include:
- Hot flashes
- Joint pain or stiffness
- Fatigue
- Nausea
- Headache
- Increased sweating Serious side effects include:
- Bone thinning or osteoporosis
- Heart problems like arrhythmia
- Liver toxicity: Elevated liver enzymes
- Severe allergic reactions: Rash, swelling, difficulty breathing
Precautions:
- Bone health: Letrozole may increase the risk of osteoporosis and bone fractures. Regular bone density monitoring is recommended.
- Pregnancy and breastfeeding: Contraindicated during pregnancy and breastfeeding, as it can harm the fetus or infant.
- Liver function: Dose adjustments may be necessary for patients with liver impairment.
Storage:
Store Letrozole tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Letrozole (Letroheal) 2.5mg is an effective treatment for hormone receptor-positive breast cancer in postmenopausal women. It significantly reduces the risk of cancer recurrence, but patients should be monitored regularly for side effects, especially bone health and liver function.
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Letrozole Tablets (Letroz 2.5 mg Tablets)
Product Price: Rs 150 / StripGet Best Price
Product Brochure
Product Details:
| Dose/Strength | 2.5 mg |
| Strength | 2.5 mg |
| Brand | Letroz |
| Tablets per Pack | 30 Tablets |
| Packaging Size | 30 Tablets in 1 Bottle |
| Composition | Letrozole 2.5 mg |
| Treatment | Breast cancer |
| Brand Name | Letroz 2.5 mg Tablets |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
Letrozole Tablets (Letroz 2.5 mg Tablets)
Overview:Letrozole 2.5 mg Tablets contain Letrozole, a non-steroidal aromatase inhibitor used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Letrozole works by inhibiting the enzyme aromatase, which is responsible for converting androgens into estrogens. By lowering estrogen levels in the body, Letrozole helps slow the growth of estrogen-dependent breast cancer cells.
Indications:Letrozole 2.5 mg Tablets are indicated for:
- Early-stage Hormone Receptor-Positive Breast Cancer: As an adjuvant treatment in postmenopausal women, either alone or following surgery, radiation, or chemotherapy.
- Advanced or Metastatic Hormone Receptor-Positive Breast Cancer: In postmenopausal women, Letrozole is used to treat advanced breast cancer, either alone or in combination with other treatments.
- Prevention of Recurrence: In women with early breast cancer to reduce the risk of recurrence, particularly after tamoxifen therapy.
Letrozole works by inhibiting aromatase, the enzyme responsible for converting androgens (male hormones) into estrogens. Estrogen promotes the growth of certain types of breast cancer cells. By lowering estrogen production, Letrozole deprives hormone-sensitive breast cancer cells of the estrogen needed for growth, leading to tumor shrinkage and reduced cancer progression.
Dosage and Administration:- Recommended Dose: The usual dose of Letrozole 2.5 mg is one tablet once daily.
- Administration: The tablet can be taken with or without food and should be swallowed whole with water. It is important to take Letrozole at the same time each day to maintain consistent drug levels in the body.
- Common Side Effects: Hot flashes, joint pain, fatigue, nausea, sweating, and headache.
- Serious Side Effects: Osteoporosis, fractures, cardiovascular issues, liver dysfunction, and an increased risk of blood clots. Regular bone density monitoring is recommended during treatment.
- Bone Health: Long-term use of Letrozole may lead to bone mineral density loss, increasing the risk of fractures. Calcium and vitamin D supplementation may be advised.
- Liver Function: Monitor liver enzymes regularly, as Letrozole can affect liver function.
- Pregnancy and Lactation: Letrozole is contraindicated during pregnancy and should not be used by women who are breastfeeding. Effective contraception should be used during treatment.
Store Letrozole 2.5 mg Tablets at room temperature (15°C to 30°C), away from light, moisture, and out of the reach of children.
Conclusion:Letrozole 2.5 mg Tablets are an essential treatment for hormone receptor-positive breast cancer in postmenopausal women. It works by reducing estrogen levels, which slows or stops the growth of estrogen-dependent cancer cells. While effective, it is important to monitor for potential side effects, particularly regarding bone health and liver function. Regular follow-ups with healthcare providers are essential for optimal management of breast cancer treatment.
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Clomifene Tablets ( Clofi 25 mg Tablets)
Product Price: Rs 250 / StripGet Best Price
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Product Details:
| Strength | 25 mg |
| Brand | Clofi |
| Packaging Size | 10 Tablets in 1 Strip |
| Composition | Clomiphene 25 mg |
| Brand Name | Clofi 25 mg |
| Manufacturer | Sunrise Remedies Pvt Ltd |
| Treatment | Female Fruitlessness |
Clomifene Tablets (Clofi 25 mg Tablets)
Overview:Clofi 25 mg Tablets contain Clomifene Citrate, a medication used to treat infertility in women, particularly in those with anovulation (lack of ovulation) or irregular menstrual cycles. Clomifene is a selective estrogen receptor modulator (SERM) that works by stimulating ovulation. It does this by blocking estrogen receptors in the hypothalamus, which increases the release of gonadotropins (follicle-stimulating hormone - FSH, and luteinizing hormone - LH). These hormones are essential for the growth and release of eggs from the ovaries, making Clofi an effective treatment for women who are struggling to conceive due to ovulatory dysfunction.
Indications:Clofi 25 mg Tablets are indicated for:
- Anovulatory Infertility: To induce ovulation in women with anovulation or irregular menstrual cycles, often used in cases of polycystic ovary syndrome (PCOS).
- Female Infertility: As a first-line treatment for infertility related to ovulatory dysfunction in women who are trying to become pregnant.
Clomifene acts by blocking estrogen receptors in the hypothalamus, which results in an increase in gonadotropin secretion from the pituitary gland. This, in turn, stimulates the ovaries to produce and mature eggs (ovulation). In some cases, Clomifene can be used to regulate menstrual cycles and improve the chances of conception. The increase in FSH and LH promotes follicular growth, and if ovulation occurs, the egg is released, allowing for the possibility of pregnancy.
Dosage and Administration:- Recommended Dose: The typical starting dose is 25 mg daily for 5 days, starting on the 5th day of the menstrual cycle. If ovulation does not occur, the dose may be increased in subsequent cycles.
- Administration: Take one tablet daily at the same time each day, starting on the 5th day of the menstrual cycle. The tablet should be swallowed whole with water, with or without food.
- Common Side Effects: Hot flashes, headache, nausea, mood swings, abdominal discomfort, and bloating.
- Serious Side Effects: Ovarian hyperstimulation syndrome (OHSS), visual disturbances, and multiple pregnancies (twins or more). Prolonged use may also increase the risk of ovarian cysts.
- Ovarian Cysts: Monitor for the development of ovarian cysts as Clomifene can stimulate the ovaries and cause abnormal cyst formation. If large cysts are detected, treatment may need to be paused.
- Multiple Pregnancies: Clomifene increases the risk of multiple pregnancies (e.g., twins). Women undergoing treatment should be aware of this risk.
- Pregnancy: Clofi should not be used during pregnancy, and a pregnancy test should be performed before starting treatment. If pregnancy occurs, treatment should be discontinued.
- Liver Disease: Use with caution in patients with liver impairment. Regular liver function tests may be needed.
Store Clofi 25 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Clomifene Tablets (Clofi 25 mg) are an effective treatment for women with anovulatory infertility, helping to stimulate ovulation and improve the chances of conception. Regular monitoring for potential side effects like ovarian cysts and the risk of multiple pregnancies is important. As a first-line fertility drug, Clomifene has been a cornerstone in treating women struggling with infertility due to ovulatory dysfunction.
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10mg Cytotam Tamoxifen Citrate Tablet
Product Price: Rs 110 / StripGet Best Price
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Product Details:
| Strength | 10 mg |
| Dosage/Strength | 10 mg |
| Tablets per Pack | 10 Tablets |
| Form | Tablet |
| Brand | Cipla |
| Usage | Used To Treat And Prevent Breast Cancer |
| Pack Type | Box |
| Pack Size | 10x10 Tablets |
| Shelf Life | 24 Months |
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Evista Raloxifene Hydrochloride (Raloxiheal Tablet)
Product Price: Rs 250 / StripGet Best Price
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Product Details:
| Strength | 60 mg |
| Form | Tablet |
| Treatment | Osteoporosis |
| Pack Size | 10 Tablets in 1 Strip |
| Composition (Salt) | Raloxifene Hydrochloride 60 mg |
| Brand Name | Raloxiheal Tablet |
| Manufacturers | Healing Pharma |
| Brand | Raloxiheal |
Evista Raloxifene Hydrochloride (Raloxiheal Tablet)
Overview:Evista (Raloxifene Hydrochloride), also known as Raloxiheal Tablet, is a selective estrogen receptor modulator (SERM) used primarily in the prevention and treatment of osteoporosis in postmenopausal women. It also reduces the risk of breast cancer in women with osteoporosis or those at high risk. Raloxifene mimics estrogen’s beneficial effects on bone density but does not have the same effects on the breast and uterine tissues, making it a safer alternative to hormone replacement therapy (HRT).
Indications:Evista (Raloxiheal) is indicated for:
- Prevention and Treatment of Osteoporosis: In postmenopausal women, Evista helps to increase bone mass and reduce the risk of fractures.
- Breast Cancer Risk Reduction: In postmenopausal women with osteoporosis or at high risk of breast cancer, Evista has been shown to reduce the incidence of invasive breast cancer.
Raloxifene works by binding to estrogen receptors in bone tissue, exerting estrogen-like effects that help maintain bone mineral density and reduce the rate of bone resorption. By doing so, it helps to increase bone strength and reduce the risk of fractures in postmenopausal women. In breast and uterine tissue, however, Raloxifene acts as an estrogen antagonist, meaning it blocks the effects of estrogen, reducing the risk of estrogen-driven breast cancers.
Dosage and Administration:- Recommended Dose: The usual dose is one 60 mg tablet daily.
- Administration: Take the tablet orally, with or without food. It should be swallowed whole with water. It’s important to take Raloxiheal regularly to maximize its effectiveness in preventing bone loss and reducing the risk of breast cancer.
- Common Side Effects: Hot flashes, leg cramps, flu-like symptoms, joint pain, and sweating.
- Serious Side Effects: Blood clots, deep vein thrombosis (DVT), pulmonary embolism, and stroke. Women with a history of blood clots or those who are immobile should be monitored carefully.
- Blood Clots: Raloxifene can increase the risk of blood clots. Women with a history of DVT, pulmonary embolism, or stroke should avoid Raloxifene.
- Liver Function: Monitor liver enzymes, as Raloxifene can impact liver function in some patients.
- Pregnancy and Lactation: Contraindicated during pregnancy as it can harm the fetus. It is not recommended during breastfeeding.
Store Evista (Raloxiheal) tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Evista Raloxifene Hydrochloride (Raloxiheal Tablets) offers a dual benefit for postmenopausal women, promoting bone health and reducing breast cancer risk. While generally well tolerated, it requires monitoring for blood clot risk and liver function. Regular follow-up with healthcare providers ensures safe and effective use of this medication.
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Gefitinib Geffy 250 mg Tablet
Product Price: Rs 2,500 / BoxGet Best Price
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Product Details:
| Strength | 250 mg |
| Dose/Strength | 250 mg |
| Brand | Geffy |
| Packaging Size | 1*10 Tablets |
| Composition | Gefitinib 250 mg |
| Brand Name | Geffy 250 mg Tablet |
| Manufactured By | Intas Pharmaceuticals Ltd |
| Treatment | Non-small Cell Lung Cancer |
Geffy 250mg Tablet (Gefitinib)
Overview:
Geffy (Gefitinib) is an oral medication used to treat non-small cell lung cancer (NSCLC) that has specific mutations in the epidermal growth factor receptor (EGFR) gene. As a tyrosine kinase inhibitor (TKI), Gefitinib works by blocking the action of EGFR, a protein that promotes the growth of cancer cells. By inhibiting EGFR, Geffy slows or stops the growth of cancer cells and helps control tumor spread.
Indications:
Geffy 250mg Tablets are primarily indicated for:
- Non-Small Cell Lung Cancer (NSCLC): In patients with EGFR mutation-positive tumors who have not received prior chemotherapy.
- Advanced or metastatic NSCLC: In patients who have already received chemotherapy and have EGFR mutations.
Mechanism of Action:
Gefitinib works by selectively binding to the EGFR tyrosine kinase receptor, blocking its activity. This inhibits the activation of downstream signaling pathways that are involved in cell proliferation, survival, and metastasis, thereby reducing tumor growth. EGFR mutations in cancer cells make them more susceptible to Gefitinib's action, leading to tumor shrinkage or stabilization.
Dosage and Administration:
- Recommended Dose: The typical dose of Geffy is 250mg once daily, taken orally with or without food.
- Administration: The tablet should be swallowed whole with water. Do not crush, chew, or break the tablet.
- Missed Dose: If a dose is missed, take it as soon as possible unless it’s near the time for the next dose.
Side Effects:
Common side effects include:
- Diarrhea
- Skin rash or acne-like lesions
- Nausea
- Loss of appetite
- Fatigue Serious side effects include:
- Interstitial lung disease: Can cause lung problems, leading to breathing difficulties.
- Hepatotoxicity: Elevated liver enzymes and potential liver damage.
- Severe skin reactions: Rash or blistering.
Precautions:
- Liver problems: Liver function should be monitored during treatment.
- Pulmonary effects: Monitor for signs of lung disease, including cough and difficulty breathing.
- Pregnancy and breastfeeding: Geffy should be avoided during pregnancy as it can harm the fetus.
Storage:
Store Geffy tablets at room temperature (20°C to 25°C), away from moisture and heat. Keep the bottle tightly closed.
Conclusion:
Geffy 250mg Tablet (Gefitinib) is an effective treatment option for EGFR mutation-positive NSCLC. Regular monitoring for side effects, especially related to liver function and lung health, is crucial to ensure the safe use of this medication.
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550mg Rifguard Rifaximin Tablet
Product Price: Rs 450 / BoxGet Best Price
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Product Details:
| Strength | 550 mg |
| Pack Size | 15 tablets |
| Brand | Rifguard |
| Composition | Rifaximin 550 mg |
| Pack Type | 1 Strip 15 Tablet |
| Brand Name | Rifguard 550 mg |
| Manufactured By | Hetero Health Care |
| Treatment | Travelles diarrhoea, Liver encephalopathy, Irritable bowel syndrome due to diarrhoea |
Rifaximin Tablets (Rifguard 550 mg)
Overview:
Rifguard 550 mg Tablets contain Rifaximin, a broad-spectrum antibiotic belonging to the rifamycin class. It works by inhibiting bacterial RNA synthesis, which stops bacterial growth and replication. Rifaximin is poorly absorbed in the gastrointestinal tract, allowing it to remain in the intestines where it acts locally to treat specific conditions, particularly those related to the gut.
Indications:
Rifguard 550 mg Tablets are indicated for:
- Traveler’s Diarrhea: Caused by non-invasive E. coli in adults and children over 12 years.
- Hepatic Encephalopathy: To reduce the recurrence of episodes in patients with liver disease.
- Irritable Bowel Syndrome (IBS): Specifically for IBS with diarrhea (IBS-D) in adults.
- Small Intestinal Bacterial Overgrowth (SIBO): Off-label use for treating SIBO, as Rifaximin targets bacteria overgrowth in the small intestine.
Mechanism of Action:
Rifaximin inhibits bacterial RNA synthesis by binding to the bacterial RNA polymerase, preventing the transcription process. Its primary effect is localized to the gastrointestinal tract because it is minimally absorbed systemically. It is effective against a variety of gram-positive and gram-negative bacteria, particularly those associated with gut-related infections and disorders.
Dosage and Administration:
- Traveler’s Diarrhea: 200 mg three times daily for 3 days.
- Hepatic Encephalopathy: 550 mg twice daily.
- Irritable Bowel Syndrome with Diarrhea (IBS-D): 550 mg three times daily for 14 days.
- Administration: Swallow the tablet whole with or without food. Do not crush or chew.
- Renal Impairment: No dosage adjustment is needed in patients with mild to moderate renal impairment. Caution is advised in severe renal impairment.
Side Effects:
- Common: Nausea, headache, flatulence, abdominal pain, and diarrhea.
- Serious: Severe allergic reactions (e.g., anaphylaxis), liver enzyme elevation, and Clostridium difficile-associated diarrhea (C. difficile).
- Monitor: Liver function tests in patients with hepatic disease and watch for any signs of C. difficile-associated diarrhea.
Precautions:
- Liver Disease: Use with caution in patients with liver disease, particularly in those with hepatic impairment, as Rifaximin is primarily excreted through the liver.
- C. difficile Diarrhea: Prolonged use or broad-spectrum antibiotics may lead to overgrowth of Clostridium difficile, a cause of severe diarrhea. Discontinue if symptoms of C. difficile infection arise.
- Pregnancy and Lactation: Rifaximin is classified as Category C during pregnancy, meaning it should be used only when clearly needed. It is excreted in breast milk, so caution is advised when administering to breastfeeding mothers.
Storage:
Store Rifguard 550 mg Tablets at room temperature (15°C to 30°C), in a dry place away from light and moisture. Keep out of reach of children.
Conclusion:
Rifguard (Rifaximin 550 mg Tablets) is a targeted, non-absorbed antibiotic that is effective for treating gastrointestinal conditions like traveler’s diarrhea, hepatic encephalopathy, and IBS with diarrhea. Its minimal systemic absorption makes it ideal for localized treatment in the gut. Monitoring for liver function and signs of C. difficile infection is important during therapy.
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Xbira Abiraterone 250 mg Tablet
Product Price: Rs 8,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Brand | Xbira |
| Tablets per Pack | 120 Tablets |
| Packaging Size | 120 Tablets |
| Composition | Abiraterone Acetate |
| Treatment | Treat prostate cancer |
| Manufacturer | Cipla Ltd. |
| Brand Name | Xbira 250 mg |
Overview:
Xbira 250 mg Tablets contain Abiraterone Acetate, an oral medication used to treat metastatic castration-resistant prostate cancer (mCRPC). Abiraterone is an androgen biosynthesis inhibitor that works by blocking the enzyme CYP17A1, which is involved in the production of androgens (male hormones like testosterone) in the testes, adrenal glands, and prostate tumor. By reducing androgen levels, Xbira slows the growth and spread of prostate cancer cells that rely on these hormones for growth.
- Metastatic Castration-Resistant Prostate Cancer (mCRPC): Used in combination with prednisone for the treatment of patients with mCRPC who have progressed following androgen deprivation therapy (ADT).
- High-Risk Castration-Sensitive Prostate Cancer (CSPC): For the treatment of CSPC in combination with prednisone.
Abiraterone inhibits CYP17A1, an enzyme responsible for the production of androgens. This inhibition results in reduced androgen levels, which are critical for the growth of prostate cancer cells. Abiraterone significantly decreases both testosterone and other androgenic hormones, slowing or stopping the growth of prostate cancer cells.
Dosage and Administration:- Recommended dose: 1,000 mg (4 tablets of 250 mg) once daily.
- Administer with or without food.
- Prednisone is given with Abiraterone (5 mg twice daily).
- Renal or Hepatic Impairment: Adjust dosage based on liver function; use with caution in patients with liver impairment.
Common: Fatigue, joint pain, hot flashes, diarrhea, nausea.
Serious: Liver toxicity, adrenal insufficiency, hypertension, hypokalemia, heart problems (e.g., arrhythmias).
Monitor: Liver enzymes, blood pressure, potassium levels.
- Liver Function: Monitor liver function regularly due to risk of hepatotoxicity.
- Adrenal Insufficiency: Can cause low cortisol levels, leading to fatigue, weakness, and hypotension.
- Pregnancy: Contraindicated in women who are or may become pregnant.
- CYP3A4 Interactions: Caution with drugs that affect CYP3A4 (e.g., ketoconazole, rifampin).
Store at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Xbira (Abiraterone 250 mg Tablets) is an effective treatment for mCRPC and CSPC, particularly in combination with prednisone. By inhibiting androgen production, it helps control prostate cancer growth. Regular monitoring of liver function and blood pressure is essential during treatment.
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Rubraca Rucaparib 300 mg Tablets
Product Price: Rs 1,00,000 / BottleGet Best Price
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Product Details:
| Strength | 300 mg |
| Pack Size | 60 tablets |
| Brand | Rubraca |
| Composition | Rucaparib 300 mg |
| Packaging Type | 60 Tablets in 1 Bottle |
| Brand Name | Rubraca |
| Manufactured By | Clovis Oncology |
| Treatment | Ovarian, Fallopian Tube And Primary Peritoneal Cancer |
Overview:
Rubraca 300 mg Tablets contain Rucaparib, an oral poly(ADP-ribose) polymerase (PARP) inhibitor used in the treatment of certain cancers. Rucaparib works by blocking the PARP enzyme, which is involved in repairing DNA damage in cells. In cancer cells, especially those with BRCA mutations or other DNA repair deficiencies, inhibiting PARP leads to the accumulation of DNA damage, which promotes cancer cell death. Rubraca is primarily used in the treatment of ovarian cancer, prostate cancer, and other cancers with defective DNA repair mechanisms.
- Ovarian Cancer: Treatment of recurrent ovarian cancer in adults who have been treated with platinum-based chemotherapy and have a BRCA mutation (both germline and somatic).
- Prostate Cancer: For the treatment of metastatic castration-resistant prostate cancer (mCRPC) in patients with a BRCA mutation.
- Other Cancers: Used off-label in cancers with certain DNA repair deficiencies (e.g., BRCA mutations).
Rucaparib is a PARP inhibitor that blocks the PARP1 and PARP2 enzymes, which repair single-strand DNA breaks. In cancer cells with BRCA mutations or other defects in DNA repair, blocking PARP leads to double-strand breaks and prevents repair, causing cell death and reducing cancer cell proliferation.
Dosage and Administration:- Ovarian Cancer: 600 mg (two 300 mg tablets) twice daily.
- Prostate Cancer: 600 mg twice daily, based on medical guidance.
- Take with or without food.
- Renal Impairment: Adjust dose in cases of severe renal dysfunction.
Common: Nausea, fatigue, anemia, decreased appetite, constipation, vomiting.
Serious: Myelodysplastic syndrome (MDS), acute leukemia, liver toxicity, bone marrow suppression, and pneumonitis.
Monitor: Regular blood counts, liver function tests, and renal function.
- Bone Marrow Suppression: Monitor for signs of anemia, neutropenia, and thrombocytopenia.
- Liver Dysfunction: Use with caution in patients with liver disease.
- Pregnancy and Lactation: Contraindicated during pregnancy and breastfeeding.
- Drug Interactions: Use caution with CYP3A4 inhibitors or inducers.
Store at room temperature (15°C to 30°C), away from moisture and light. Keep out of reach of children.
Conclusion:Rubraca (Rucaparib 300 mg Tablets) is an effective treatment for ovarian cancer and prostate cancer with BRCA mutations. By inhibiting DNA repair, it helps eliminate cancer cells with defective repair mechanisms. Regular monitoring of blood counts and liver function is essential during therapy.
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Gefzest Gefitinib 250mg Tablets
Product Price: Rs 2,300 / BoxGet Best Price
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Product Details:
| Strength | 250 mg |
| Dose/Strength | 250 mg |
| Brand | Gefzest |
| Packaging Size | 30 tablets |
| Composition | Geftinib 250 mg |
| Pack Type | 3*10 Tablets |
| Brand Name | Gefzest 250 mg |
| Manufactured By | United Biotech Pvt Ltd |
| Treatment | Non-small cell lung cancer |
Gefzest Gefitinib 250 mg Tablets
Overview:
Gefzest 250 mg Tablets contain Gefitinib, an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) used for the treatment of non-small cell lung cancer (NSCLC). Gefitinib works by inhibiting the EGFR, which plays a key role in the growth and spread of cancer cells. By blocking this receptor, Gefitinib can slow tumor growth and help control the spread of cancer, particularly in patients with EGFR mutations.
Indications:
Gefzest 250 mg Tablets are indicated for:
- Non-Small Cell Lung Cancer (NSCLC): For the treatment of locally advanced or metastatic NSCLC with EGFR mutations (exon 19 deletions or exon 21 L858R substitution mutations) who have not received prior chemotherapy or have progressed after previous chemotherapy.
Mechanism of Action:
Gefitinib selectively inhibits the EGFR receptor, a cell surface protein involved in the activation of signaling pathways that regulate tumor cell growth, survival, and metastasis. By blocking EGFR tyrosine kinase activity, Gefitinib disrupts downstream signaling, inhibiting cell proliferation and promoting apoptosis (cell death) in EGFR-mutant tumor cells.
Dosage and Administration:
- Recommended Dose: 250 mg once daily, taken orally.
- Administration: Swallow the tablet whole with or without food. Do not crush or chew the tablet. Take at the same time each day to maintain consistent drug levels in the body.
Side Effects:
- Common: Diarrhea, skin rash, acne, nausea, decreased appetite, fatigue.
- Serious: Hepatotoxicity, interstitial lung disease (ILD), ocular disorders (e.g., corneal disorders), and severe skin reactions. Regular liver function tests and monitoring for lung and skin-related side effects are recommended during treatment.
Precautions:
- Liver Impairment: Gefitinib can cause liver toxicity. Regular liver function tests are advised, especially in patients with pre-existing liver conditions.
- Interstitial Lung Disease (ILD): Monitor for signs of ILD (e.g., cough, difficulty breathing), as it can be life-threatening.
- Ocular Disorders: Eye-related side effects (e.g., keratitis) are possible, requiring eye exams if symptoms develop.
- Pregnancy and Lactation: Gefitinib is contraindicated during pregnancy and breastfeeding. Women of childbearing potential should use effective contraception during treatment.
Storage:
Store Gefzest 250 mg Tablets at room temperature (15°C to 30°C), in a dry place away from light and moisture. Keep out of reach of children.
Conclusion:
Gefzest (Gefitinib 250 mg Tablets) is an effective treatment option for patients with advanced or metastatic non-small cell lung cancer with EGFR mutations. By inhibiting EGFR signaling, it helps control cancer growth. Regular monitoring for liver function, lung toxicity, and skin conditions is necessary to ensure safety during treatment.
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Tolvat 15 Tolvaptan Tablet
Product Price: Rs 540 / BoxGet Best Price
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Product Details:
| Tolvaptan Strength | 15 mg |
| Strength | 15 mg |
| Indication | Hyponatremia |
| Dose Form | Tablet |
| Packaging Type | Box |
| Packaging Size | 1*4 Tablets |
| Shelf Life | 24 Months |
| Brand | MSN |
| Form | Tablets |
| Usage | Used To Treat Hyponatremia |
Overview:
Tolvat 15 mg Tablets contain Tolvaptan, a vasopressin V2 receptor antagonist used in the treatment of hyponatremia (low blood sodium) and certain kidney diseases, particularly autosomal dominant polycystic kidney disease (ADPKD). Tolvaptan works by blocking the action of vasopressin, a hormone that regulates water balance in the body, thereby increasing water excretion in the kidneys without losing electrolytes like sodium.
- Hyponatremia: Treatment of clinically significant hyponatremia in patients with heart failure, liver cirrhosis, or SIADH (syndrome of inappropriate antidiuretic hormone secretion).
- Autosomal Dominant Polycystic Kidney Disease (ADPKD): To slow the progression of kidney damage in adults with ADPKD who have evidence of rapidly progressing disease (e.g., rapid kidney enlargement or decline in kidney function).
Tolvaptan works by selectively inhibiting the vasopressin V2 receptors in the kidneys. Vasopressin normally acts on these receptors to promote water retention. By blocking this action, Tolvaptan increases the excretion of free water, which helps to correct hyponatremia. In ADPKD, it reduces cyst growth and slows kidney function decline by decreasing the effect of vasopressin on cyst formation and enlargement.
Dosage and Administration:- Hyponatremia: Initial dose is usually 15 mg once daily, which can be increased to 30 mg or 60 mg based on serum sodium levels and clinical response.
- ADPKD: Starting dose is 60 mg once daily, with a possible dose increase to 90 mg or 120 mg depending on tolerance and response.
- Administration: Take orally with or without food. Tablets should be swallowed whole.
Common: Thirst, dry mouth, polyuria (increased urination), nausea, and fatigue.
Serious: Liver toxicity (hepatotoxicity), hyperkalemia (high potassium), dehydration, and orthostatic hypotension (low blood pressure).
Monitor: Regular liver function tests, renal function, and serum electrolytes (especially sodium and potassium).
- Liver Dysfunction: Tolvaptan can cause significant liver injury, so regular monitoring of liver enzymes is required, particularly in the first 18 months of therapy.
- Dehydration: Monitor for signs of dehydration or excessive fluid loss. Adjust dose as necessary.
- Pregnancy and Lactation: Contraindicated during pregnancy and breastfeeding due to potential risks to the fetus and infant.
- Renal Impairment: Use with caution in patients with significant renal impairment.
Store at room temperature (15°C to 30°C), in a dry place, away from light and moisture. Keep out of reach of children.
Conclusion:Tolvat (Tolvaptan 15 mg Tablets) is an effective treatment for hyponatremia and autosomal dominant polycystic kidney disease (ADPKD). By inhibiting vasopressin's action, it helps correct sodium imbalances and slow kidney damage. Due to potential side effects such as liver toxicity, regular monitoring of liver function, electrolytes, and kidney function is essential.
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