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Anti Cancer Tablet - 3
Our product range includes a wide range of ribociclib valamor 200 mg tablet, soranib sorafenib 200 mg tablets, tamoxifen caditam 20 mg tablet, tamoxifen caditam 10 mg, ramiven 100 mg tablets abemaciclib and imatinib tablets (veenat 400 mg tablets).
Ribociclib Valamor 200 mg Tablet
Product Price: Rs 23,500 / BoxGet Best Price
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Product Details:
| Strength | 200 mg |
| Pack Size | 63 Tablet |
| Composition | Ribociclib 200 mg |
| Brand | Valamor 200 mg |
| Manufacturer | Farmanova |
| Treatment | Metastatic Breast Cancer |
Valamor (Ribociclib) 200 mg Tablets
Overview: Valamor contains ribociclib, a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6) used primarily in the treatment of hormone receptor-positive, HER2-negative breast cancer. It is indicated for use in combination with endocrine therapy for patients with advanced or metastatic disease.
Indications- Breast Cancer: Used in combination with an aromatase inhibitor or fulvestrant for the treatment of HR-positive, HER2-negative breast cancer in:
- Postmenopausal women.
- Men with this specific type of breast cancer.
Ribociclib selectively inhibits CDK4 and CDK6, which are essential for cell cycle progression. By inhibiting these kinases, ribociclib helps to slow or stop the proliferation of cancer cells.
Dosage and Administration- Dosage: The recommended starting dose is typically 600 mg taken once daily for 21 consecutive days, followed by a 7-day break. The 200 mg tablet may be used for dose adjustments as needed.
- Administration: Take the tablets orally, with or without food, preferably at the same time each day.
Common side effects may include:
- Neutropenia (low white blood cell count)
- Fatigue
- Nausea
- Diarrhea
- Elevated liver enzymes
- Hair loss
- Neutropenia: Regular blood tests are essential to monitor blood cell counts due to the risk of infections.
- Liver Function: Liver function tests should be performed before and during treatment; dose adjustments may be necessary for elevated liver enzymes.
- QT Prolongation: Monitor for QT interval prolongation; ECGs may be warranted in certain patients.
- Hypersensitivity: Contraindicated in individuals with known allergies to ribociclib or any components of the formulation.
Ribociclib may interact with:
- CYP3A4 Inhibitors and Inducers: These can affect ribociclib levels, requiring careful monitoring and potential dose adjustments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently and report any signs of infection or severe side effects.
- Educate about the potential for neutropenia and the importance of regular blood monitoring.
- Encourage patients to notify their healthcare provider of any other medications they are taking to avoid interactions.
Valamor (Ribociclib 200 mg Tablets) is an important treatment option for specific types of breast cancer. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Soranib Sorafenib 200 mg Tablets
Product Price: Rs 5,500 / BottleGet Best Price
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Product Details:
| Packaging Size | 120 Tablets |
| Strength | 200 mg |
| Composition | Sorafenib 200 mg |
| Brand | Soranib 200 mg |
| Manufacturer | Cipla Ltd |
| Treatment | Kidney Cancer |
Soranib (Sorafenib) 200 mg Tablets
Overview: Soranib contains sorafenib, an oral multikinase inhibitor used primarily in the treatment of certain types of cancers. It works by inhibiting tumor cell proliferation and angiogenesis (the formation of new blood vessels that supply tumors).
Indications- Renal Cell Carcinoma: Treatment of advanced renal cell carcinoma (kidney cancer) in patients who have received prior therapy.
- Hepatocellular Carcinoma: Indicated for the treatment of unresectable hepatocellular carcinoma (liver cancer) in patients who are not candidates for surgical resection or liver transplantation.
- Differentiated Thyroid Cancer: For the treatment of radioactive iodine-refractory differentiated thyroid carcinoma.
Sorafenib inhibits multiple kinases involved in tumor growth and angiogenesis, including:
- VEGFR-2 and VEGFR-3: Involved in the formation of new blood vessels.
- PDGFR-β: Promotes tumor growth.
- RAF kinases: Affect signaling pathways related to cell proliferation and survival.
By blocking these pathways, sorafenib helps to slow down or stop the growth of cancer cells.
Dosage and Administration- Dosage: The typical dose is usually 400 mg taken orally twice daily. The 200 mg tablet can be used for dose adjustments based on tolerability.
- Administration: Tablets should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal, and should be swallowed whole with water.
Common side effects may include:
- Diarrhea
- Fatigue
- Hand-foot skin reaction (redness, swelling, pain on palms and soles)
- Nausea
- Hypertension (high blood pressure)
- Rash
- Hemorrhage: Monitor for signs of bleeding, as serious hemorrhagic events can occur.
- Cardiovascular Events: Use with caution in patients with a history of heart disease, as there may be an increased risk of cardiovascular events.
- Liver Function: Regular liver function tests are recommended, especially in patients with pre-existing liver conditions.
- Hypersensitivity: Contraindicated in individuals with known allergies to sorafenib or any components of the formulation.
- Pregnancy and Breastfeeding: Not recommended due to potential risks to the fetus or infant.
Sorafenib may interact with:
- CYP3A4 Inhibitors and Inducers: Medications that affect the metabolism of sorafenib may alter its effectiveness and safety.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and to report any side effects, particularly severe skin reactions or signs of bleeding.
- Educate about the importance of regular follow-up appointments and blood tests.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Soranib (Sorafenib 200 mg Tablets) is an important treatment option for various cancers, particularly advanced renal cell carcinoma and hepatocellular carcinoma. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Tamoxifen Caditam 20 mg Tablet
Product Price: Rs 350 / StripeGet Best Price
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Product Details:
| Dosage/Strength | 20 mg |
| Packaging Size | 10*10 Tablets |
| Composition | Temoxifen 20 mg |
| Brand | Caditam 20 mg |
| Manufacturer | cadila |
| Treatment | Chronic Hepatitis C Virus (HCV) Infection |
Caditam (Tamoxifen) 20 mg Tablets
Overview: Caditam contains tamoxifen, a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of hormone receptor-positive breast cancer. It blocks estrogen's effects on breast tissue, helping to slow or stop the growth of certain tumors.
Indications:
- Breast Cancer Treatment: Used in the adjuvant treatment of estrogen receptor-positive breast cancer in women and men.
- Breast Cancer Prevention: May be used to reduce the risk of developing breast cancer in women at high risk.
Mechanism of Action: Tamoxifen binds to estrogen receptors, inhibiting estrogen's action on breast cancer cells, thereby reducing tumor growth.
Dosage and Administration:
- Recommended Dose: Typically, 20 mg taken orally once daily, but dosage may vary based on individual treatment plans.
- Administration: Can be taken with or without food. Consistency in timing is recommended.
Side Effects: Common side effects may include:
- Hot flashes
- Nausea
- Fatigue
- Vaginal discharge or bleeding
- Increased risk of blood clots (thrombosis)
Warnings and Precautions:
- Thromboembolic Events: Risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism.
- Endometrial Cancer: Long-term use may increase the risk of endometrial cancer; patients should be monitored for unusual vaginal bleeding.
- Liver Function: Monitor liver function, as tamoxifen can affect liver health.
Contraindications:
- Hypersensitivity to tamoxifen or its components.
- History of thromboembolic disorders.
- Not recommended during pregnancy or breastfeeding.
Drug Interactions: Tamoxifen may interact with other medications, especially those affecting liver enzymes (CYP2D6). Patients should inform their healthcare provider about all medications and supplements they are taking.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and report any side effects, especially signs of blood clots (e.g., swelling, pain in the legs, shortness of breath).
- Emphasize the importance of regular follow-up appointments to monitor treatment efficacy and any potential side effects.
- Discuss lifestyle changes that may help manage side effects.
Caditam (Tamoxifen) 20 mg Tablets are an important treatment option for hormone receptor-positive breast cancer. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment recommendations.
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Tamoxifen Caditam 10 mg
Product Price: Rs 65 / StripeGet Best Price
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Product Details:
| Dosage/Strength | 10 mg |
| Packaging Size | 20*10 Tablets |
| Composition | Tamoxifen 10 mg |
| Brand | Caditam 10 mg |
| Manufacturer | Cadila Pharmaceuticals Ltd |
| Treatment | Breast Cancer |
Caditam (Tamoxifen) 10 mg Tablets
Overview: Caditam contains tamoxifen, a selective estrogen receptor modulator (SERM) primarily used in the treatment of hormone receptor-positive breast cancer. It works by blocking estrogen receptors in breast tissue, which helps to slow or stop the growth of estrogen-dependent tumors.
Indications:
- Breast Cancer Treatment: Used in the adjuvant treatment of breast cancer in women and men, particularly for those with estrogen receptor-positive tumors.
- Breast Cancer Prevention: May be used to reduce the risk of developing breast cancer in women at high risk.
Mechanism of Action: Tamoxifen competes with estrogen for binding to estrogen receptors on breast cancer cells. By blocking estrogen, it helps to inhibit the growth of tumors that rely on this hormone.
Dosage and Administration:
- Recommended Dose: The usual dose is 10 mg to 20 mg taken orally once or twice daily, depending on the specific treatment plan.
- Administration: Can be taken with or without food. It is important to take it consistently at the same time each day.
Side Effects: Common side effects may include:
- Hot flashes
- Nausea
- Fatigue
- Vaginal discharge or bleeding
- Risk of blood clots (thrombosis)
Warnings and Precautions:
- Thromboembolic Events: Increased risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism.
- Endometrial Cancer: Long-term use may increase the risk of endometrial cancer; patients should be monitored for any unusual vaginal bleeding.
- Liver Function: Regular monitoring of liver function is recommended, as tamoxifen can cause liver issues.
Contraindications:
- Hypersensitivity to tamoxifen or any components of the formulation.
- History of thromboembolic disorders.
- Not recommended during pregnancy or breastfeeding due to potential risks.
Drug Interactions: Tamoxifen may interact with other medications, particularly those that affect liver enzymes (CYP2D6). Patients should inform their healthcare provider about all medications and supplements they are taking.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any side effects, particularly signs of blood clots (e.g., swelling, pain in the legs, shortness of breath).
- Emphasize the importance of regular follow-up appointments to monitor treatment effectiveness and any potential side effects.
- Discuss potential lifestyle changes, including diet and exercise to help manage side effects.
Caditam (Tamoxifen) 10 mg Tablets are an important treatment option for hormone receptor-positive breast cancer. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment recommendations.
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Ramiven 100 mg Tablets Abemaciclib
Product Price: Rs 21,500 / BoxGet Best Price
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Product Details:
| Strength | 100 mg |
| Pack Size | 7 Tablets in 1 Strip |
| Composition | Abemaciclib 100 mg |
| Brand | Ramiven 100 mg |
| Manufecturer | Eli Lilly and Company India Pvt Ltd |
| Treatment | Metastatic Breast Cancer |
Ramiven (Abemaciclib) 100 mg Tablets
Overview: Ramiven contains abemaciclib, a targeted therapy used in the treatment of hormone receptor-positive, HER2-negative breast cancer. It is particularly indicated for patients with advanced or metastatic breast cancer and can be used in combination with endocrine therapy.
Indications- Breast Cancer: Used for the treatment of HR-positive, HER2-negative breast cancer in:
- Patients with advanced or metastatic disease.
- Patients who have received prior endocrine therapy.
Abemaciclib is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). By inhibiting these kinases, it disrupts the cell cycle, leading to reduced cancer cell proliferation.
Dosage and Administration- Dosage: The recommended starting dose is typically 150 mg taken twice daily. The specific regimen may vary based on individual patient factors and the combination therapy used.
- Administration: Tablets should be taken orally, with or without food. It is important to take them at the same times each day.
Common side effects may include:
- Diarrhea
- Neutropenia (low white blood cell count)
- Fatigue
- Nausea
- Liver enzyme elevation
- Abdominal pain
- Neutropenia: Regular monitoring of blood counts is essential due to the risk of infections.
- Liver Function: Liver function tests should be conducted before and during treatment, as dose adjustments may be necessary for elevated liver enzymes.
- Diarrhea: Monitor and manage diarrhea, which can be a common side effect.
- Hypersensitivity: Contraindicated in individuals with known allergies to abemaciclib or any components of the formulation.
Abemaciclib may interact with:
- CYP3A4 Inhibitors and Inducers: These can affect abemaciclib levels, requiring careful monitoring and potential dose adjustments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently and to report any signs of infection or severe side effects.
- Educate about the potential for diarrhea and the importance of maintaining hydration.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid interactions.
Ramiven (Abemaciclib 100 mg Tablets) is an effective treatment option for specific breast cancers. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Imatinib Tablets (Veenat 400 mg Tablets)
Product Price: Rs 1,250 / BoxGet Best Price
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Product Details:
| Dose/Strength | 400 mg |
| Pack Size | 3*10 Tablets |
| Composition | Imatinib mesylate 400 mg |
| Brand Name | Veenat 400 mg |
| Manufactured By | Natco Pharma Ltd |
| Treatment | Blood Cancer |
Veenat (Imatinib) 400 mg Tablets
Overview: Veenat contains imatinib, a targeted therapy primarily used in the treatment of certain types of cancer, including chronic myeloid leukemia (CML) and gastrointestinal stromal tumors (GISTs). It is a tyrosine kinase inhibitor that specifically targets the BCR-ABL fusion protein associated with CML and other growth factor receptors involved in tumor growth.
Indications- Chronic Myeloid Leukemia (CML): For the treatment of adult patients with newly diagnosed Ph+ CML in chronic phase or with accelerated phase.
- Gastrointestinal Stromal Tumors (GISTs): For the treatment of GISTs that are unresectable or metastatic, particularly in cases where there is a mutation in the c-KIT gene.
Imatinib selectively inhibits the activity of specific tyrosine kinases, including the BCR-ABL fusion protein in CML and c-KIT in GISTs. By blocking these kinases, imatinib helps to prevent cancer cell proliferation and survival.
Dosage and Administration- Dosage: The usual starting dose for adults is 400 mg taken orally once daily. Dosing may be adjusted based on individual response and tolerance.
- Administration: Tablets should be taken with a meal and a full glass of water to reduce gastrointestinal side effects.
Common side effects may include:
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Edema (swelling)
- Skin rash
- Muscle cramps
- Hematologic Effects: Monitor for low blood cell counts, such as neutropenia and thrombocytopenia.
- Liver Function: Liver function tests should be performed regularly, as imatinib can cause liver enzyme elevations.
- Cardiac Monitoring: Patients with pre-existing heart conditions should be monitored closely due to potential fluid retention and heart issues.
- Hypersensitivity: Contraindicated in individuals with known allergies to imatinib or any components of the formulation.
Imatinib may interact with:
- CYP3A4 Inhibitors and Inducers: These can alter imatinib levels, requiring careful monitoring and potential dose adjustments.
- Anticoagulants: Monitor for increased bleeding risk if used in conjunction with blood thinners.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently with meals.
- Educate about potential side effects, particularly gastrointestinal issues, and encourage reporting any severe reactions.
- Emphasize the importance of regular follow-up appointments for monitoring blood counts and liver function.
Veenat (Imatinib 400 mg Tablets) is a critical treatment option for specific hematologic cancers. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Votrient Pazopanib 200 mg Tablet
Product Price: Rs 6,500 / BottleGet Best Price
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Product Details:
| Dose/Strength | 200 mg |
| Packaging Size | 30 Tablet in 1 Box |
| Composition | Pazopanib 200 mg |
| Brand | Votrient 200 mg |
| Manufacturer | Glaxo SmithKline Pharmaceuticals Ltd |
| Treatment | Kidney Cancer |
Votrient (Pazopanib) 200 mg Tablets
Overview: Votrient contains pazopanib, a targeted therapy used primarily for the treatment of advanced renal cell carcinoma (kidney cancer) and soft tissue sarcoma. It is an oral tyrosine kinase inhibitor that affects multiple receptors involved in tumor growth and angiogenesis.
Indications- Renal Cell Carcinoma (RCC): For the treatment of advanced or metastatic renal cell carcinoma.
- Soft Tissue Sarcoma: For the treatment of patients with advanced soft tissue sarcoma who have received prior chemotherapy.
Pazopanib inhibits multiple receptor tyrosine kinases, including:
- Vascular endothelial growth factor receptors (VEGFR)
- Platelet-derived growth factor receptors (PDGFR)
- c-KIT
By blocking these receptors, pazopanib helps to prevent tumor cell proliferation and the formation of new blood vessels.
Dosage and Administration- Dosage: The usual recommended dose for adults is 800 mg taken once daily. For patients requiring dose adjustments due to side effects, the 200 mg tablet may be used as part of a modified regimen.
- Administration: Take the tablets orally on an empty stomach, at least one hour before or two hours after a meal to ensure proper absorption.
Common side effects may include:
- Diarrhea
- Fatigue
- Nausea and vomiting
- High blood pressure
- Liver enzyme elevations
- Hair color changes
- Hepatotoxicity: Monitor liver function tests regularly, as pazopanib can cause liver enzyme elevations.
- Cardiovascular Risk: Monitor blood pressure regularly due to the risk of hypertension.
- Gastrointestinal Perforation: Patients should be monitored for gastrointestinal symptoms, as there is a risk of perforation.
- Hypersensitivity: Contraindicated in individuals with known allergies to pazopanib or any components of the formulation.
Pazopanib may interact with:
- CYP3A4 Inhibitors and Inducers: These can affect pazopanib levels, requiring careful monitoring and potential dose adjustments.
- Other Anticancer Agents: Caution is advised when used with other anticancer drugs due to the potential for additive toxicities.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently on an empty stomach.
- Educate about potential side effects, particularly those affecting liver function and blood pressure, and encourage them to report any severe reactions.
- Emphasize the importance of regular follow-up appointments for monitoring.
Votrient (Pazopanib 200 mg Tablets) is an effective treatment option for specific cancers. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Ramiven 150 mg Tablets Abemaciclib
Product Price: Rs 22,500 / BoxGet Best Price
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Product Details:
| Strength | 150 mg |
| Packaging Size | 14 Tablets |
| Composition | Abemaciclib 150 mg |
| Brand | Ramiven 150 mg |
| Manufacturer | Eli Lilly and Company India Pvt Ltd |
| Treatment | Metastatic Breast Cancer |
Ramiven (Abemaciclib) 150 mg Tablets
Overview: Ramiven contains abemaciclib, a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It is primarily used in the treatment of hormone receptor-positive, HER2-negative breast cancer, especially in patients with advanced or metastatic disease.
Indications- Breast Cancer: Used for the treatment of HR-positive, HER2-negative breast cancer in:
- Patients with advanced or metastatic disease.
- Patients who have received prior endocrine therapy.
Abemaciclib inhibits CDK4 and CDK6, proteins that play a crucial role in cell cycle regulation. By blocking these kinases, it helps slow down or stop the proliferation of cancer cells.
Dosage and Administration- Dosage: The typical starting dose is 150 mg taken orally twice daily. The dosing schedule may vary based on individual patient factors and tolerability.
- Administration: Tablets can be taken with or without food. It’s important to take them at the same times each day for consistent absorption.
Common side effects may include:
- Diarrhea
- Neutropenia (low white blood cell count)
- Fatigue
- Nausea
- Abdominal pain
- Liver enzyme elevations
- Neutropenia: Regular monitoring of blood counts is essential due to the risk of infections.
- Liver Function: Liver function tests should be monitored before and during treatment; dose adjustments may be necessary for elevated liver enzymes.
- Diarrhea Management: Monitor for diarrhea, which can be common and may require symptomatic treatment.
- Hypersensitivity: Contraindicated in individuals with known allergies to abemaciclib or any components of the formulation.
Abemaciclib may interact with:
- CYP3A4 Inhibitors and Inducers: These can affect abemaciclib levels, requiring careful monitoring and potential dose adjustments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently and report any signs of infection or severe gastrointestinal side effects.
- Educate about managing diarrhea and maintaining hydration.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Ramiven (Abemaciclib 150 mg Tablets) is an effective treatment option for specific types of breast cancer. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Megestrol Endace 160 mg Tablet
Product Price: Rs 600 / StripeGet Best Price
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Product Details:
| Strength | 160 mg |
| Packaging Size | 3*10 Tablets |
| Composition | Megestrol 160 mg |
| Brand | Endace 160 mg |
| Manufactured By | Samarth Life Sciences Pvt Ltd |
| Treatment | Breast Cancer |
Endace (Megestrol) 160 mg Tablets
Overview: Endace contains megestrol acetate, a synthetic progestin used primarily in the treatment of certain hormone-related conditions. It is commonly used to manage weight loss and appetite in patients with cancer or AIDS and for specific cases of endometrial carcinoma.
Indications- Anorexia/Cachexia: To improve appetite and increase weight in patients with cancer or AIDS-related weight loss.
- Endometrial Carcinoma: As part of the treatment regimen for advanced or recurrent endometrial carcinoma.
Megestrol acetate works by binding to progesterone receptors, leading to a variety of effects, including appetite stimulation and inhibition of the secretion of gonadotropins. This mechanism can help in increasing appetite and improving weight gain.
Dosage and Administration- Dosage: The typical starting dose for appetite stimulation is often around 160 mg taken once daily. For cancer treatment, dosing may vary based on the specific condition and patient response.
- Administration: Tablets should be taken orally, with or without food. It is advisable to take them at the same time each day.
Common side effects may include:
- Weight gain
- Edema (swelling)
- Fatigue
- Nausea
- Insomnia
- Increased sweating
- Hormonal Effects: Monitor for signs of thromboembolic events or changes in menstrual cycle due to hormonal effects.
- Liver Function: Use with caution in patients with liver impairment, as megestrol is metabolized by the liver.
- Glucose Tolerance: May affect glucose tolerance; monitor blood sugar levels in diabetic patients.
- Hypersensitivity: Contraindicated in individuals with known allergies to megestrol acetate or any components of the formulation.
- Pregnancy: Not recommended during pregnancy due to potential hormonal effects.
Megestrol may interact with:
- Anticoagulants: Monitor INR levels if taken with warfarin, as megestrol may affect its metabolism.
- Other Hormonal Therapies: Caution is advised when used with other hormone-based treatments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently as prescribed.
- Educate about potential side effects, particularly weight gain and hormonal changes.
- Encourage reporting of any unusual symptoms or side effects, especially signs of blood clots (e.g., swelling, pain in legs, shortness of breath).
Endace (Megestrol 160 mg Tablets) is an effective treatment option for managing appetite and weight loss in specific patient populations, as well as for certain cancers. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Megestrol Endace 40 mg Tablet
Product Price: Rs 245 / StripeGet Best Price
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Product Details:
| Strength | 40 mg |
| Packaging Size | 3*10 Tablets |
| Composition | Megestrol 40 mg |
| Brand | Endace-40 mg |
| Manufactured By | Samarth Life Sciences Pvt Ltd |
| Treatment | Breast cancer |
Endace (Megestrol) 40 mg Tablets
Overview: Endace contains megestrol acetate, a synthetic progestin primarily used to treat conditions related to hormone imbalance. It is often prescribed to help manage weight loss and stimulate appetite in patients with cancer or HIV/AIDS, and it can also be used in the treatment of certain cancers.
Indications- Anorexia/Cachexia: To increase appetite and promote weight gain in patients experiencing weight loss due to cancer or AIDS.
- Endometrial Carcinoma: As part of the treatment regimen for advanced or recurrent endometrial carcinoma.
Megestrol acetate works by binding to progesterone receptors, leading to effects such as appetite stimulation and suppression of gonadotropin secretion. This mechanism helps improve appetite and facilitate weight gain.
Dosage and Administration- Dosage: The typical starting dose for appetite stimulation is usually around 40 mg taken once daily, but the exact dosing may vary based on the individual patient’s needs and specific medical conditions.
- Administration: Tablets should be taken orally, with or without food. It’s best to take them at the same time each day for consistency.
Common side effects may include:
- Weight gain
- Edema (swelling)
- Fatigue
- Nausea
- Insomnia
- Increased sweating
- Hormonal Effects: Monitor for signs of thromboembolic events and changes in menstrual cycle due to hormonal effects.
- Liver Function: Use with caution in patients with liver impairment, as megestrol is metabolized by the liver.
- Glucose Tolerance: May affect glucose metabolism; monitoring of blood sugar levels in diabetic patients is advised.
- Hypersensitivity: Contraindicated in individuals with known allergies to megestrol acetate or any components of the formulation.
- Pregnancy: Not recommended during pregnancy due to potential risks to the fetus.
Megestrol may interact with:
- Anticoagulants: Careful monitoring of INR levels is necessary if taken with warfarin, as megestrol may influence its metabolism.
- Other Hormonal Therapies: Caution is advised when used with other hormone-based treatments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently as prescribed.
- Educate about potential side effects, particularly weight gain and hormonal changes.
- Encourage reporting of any unusual symptoms, especially signs of blood clots (e.g., swelling, pain in legs, shortness of breath).
Endace (Megestrol 40 mg Tablets) is an effective treatment option for managing appetite and weight loss in specific patient populations and for certain cancers. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Resihance 40 mg Tablets
Product Price: Rs 8,500 / BottleGet Best Price
Product Brochure
Product Details:
| Packaging Size | 28 Tablets |
| Strength | 40 mg |
| Composition | Regorafenib 40 mg |
| Brand | Resihance 40 mg |
| Manufacturer | Bayer |
| Treatment | Cancer of Colon and Rectum |
Resihance (Rifapentine) 40 mg Tablets
Overview: Resihance contains rifapentine, an antibiotic primarily used in the treatment of tuberculosis (TB). It is often used in combination with other medications for the treatment of active TB and for the prevention of TB in certain high-risk populations.
Indications- Active Tuberculosis: Used in combination with other anti-TB medications to treat active pulmonary tuberculosis.
- Latent Tuberculosis Infection: For the treatment of latent TB infection in specific populations, particularly in those who are at high risk for developing TB disease.
Rifapentine works by inhibiting bacterial RNA synthesis, which effectively stops the growth of mycobacteria (the bacteria that cause TB). It is particularly effective against both actively dividing and dormant bacteria.
Dosage and Administration- Dosage: The usual dose for adults is often 10 mg/kg (up to a maximum of 600 mg) once weekly when used for latent TB, or as directed by a healthcare provider for active TB.
- Administration: Tablets should be taken orally, with or without food. It’s best to take them consistently at the same time each week.
Common side effects may include:
- Nausea
- Vomiting
- Rash
- Hepatotoxicity (liver toxicity)
- Flu-like symptoms
- Anemia
- Liver Function: Regular monitoring of liver function is essential, especially in patients with pre-existing liver conditions.
- Drug Interactions: Rifapentine may interact with other medications, particularly those metabolized by the liver (CYP450 enzymes). Consult a healthcare provider about potential interactions.
- Allergic Reactions: Monitor for signs of hypersensitivity or severe skin reactions.
- Hypersensitivity: Contraindicated in individuals with known allergies to rifapentine or any components of the formulation.
- Severe Liver Disease: Not recommended for patients with severe hepatic impairment.
Rifapentine may interact with:
- Anticoagulants: May decrease the effectiveness of anticoagulants like warfarin.
- HIV Medications: Caution is advised when used with certain antiretroviral medications, as rifapentine can affect their metabolism.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently as prescribed and not to miss doses.
- Educate about potential side effects and the importance of regular follow-up appointments for monitoring.
- Encourage reporting of any unusual symptoms, particularly those related to liver function (e.g., jaundice, dark urine).
Resihance (Rifapentine 40 mg Tablets) is an important treatment option for tuberculosis, both in its active and latent forms. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Olaparib Bracanat 100 mg Tablets
Product Price: Rs 13,500 / BoxGet Best Price
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Product Details:
| Dose/Strength | 100 mg |
| Packaging Size | 30 Tablats |
| Composition | Olaparib 100 mg |
| Brand Name | Bracanat 100 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Breast cancer |
Bracanat (Olaparib) 100 mg Tablets
Overview: Bracanat contains olaparib, a medication that belongs to a class of drugs known as PARP inhibitors. It is primarily used in the treatment of certain types of cancers, particularly those associated with inherited mutations in BRCA1 and BRCA2 genes.
Indications- Ovarian Cancer: Used for the treatment of adult patients with recurrent ovarian cancer who have received three or more prior lines of chemotherapy.
- Breast Cancer: Indicated for the treatment of patients with HER2-negative breast cancer who have a BRCA mutation and have been treated with chemotherapy.
- Pancreatic Cancer: For the treatment of patients with germline BRCA-mutated metastatic pancreatic cancer who have received at least one prior chemotherapy regimen.
Olaparib works by inhibiting the enzyme poly (ADP-ribose) polymerase (PARP), which is involved in DNA repair. By blocking this enzyme, olaparib prevents cancer cells from repairing their DNA, leading to cell death, particularly in cells that are already deficient in DNA repair mechanisms due to BRCA mutations.
Dosage and Administration- Dosage: The recommended dose is typically 300 mg taken orally twice daily. The 100 mg tablet may be used for dose adjustments as needed based on tolerability.
- Administration: Tablets should be taken with or without food. It is important to take them at the same times each day.
Common side effects may include:
- Nausea
- Fatigue
- Vomiting
- Diarrhea
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
- Myelodysplastic Syndromes/Acute Myeloid Leukemia (MDS/AML): Monitor patients for signs of MDS/AML, which may occur in some patients treated with olaparib.
- Hematologic Monitoring: Regular blood counts are recommended to monitor for anemia and thrombocytopenia.
- Liver Function: Liver enzyme levels should be monitored, especially if there are signs of liver dysfunction.
- Hypersensitivity: Contraindicated in individuals with known allergies to olaparib or any components of the formulation.
Olaparib may interact with:
- CYP3A4 Inhibitors and Inducers: Caution is advised when used with medications that can significantly alter the metabolism of olaparib.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and to report any side effects, particularly severe nausea, fatigue, or signs of infection.
- Educate about the importance of regular blood tests to monitor blood counts and liver function.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Bracanat (Olaparib 100 mg Tablets) is an effective treatment option for specific cancers associated with BRCA mutations. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Olaparib Bracanat 150 mg Tablets
Product Price: Rs 18,500 / BoxGet Best Price
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Product Details:
| Dose/Strength | 150 mg |
| Packaging Size | 30 Tablets in 1 Box |
| Composition | Olaparib 150 mg |
| Brand Name | Bracanat 150 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Breast Cancer |
Bracanat (Olaparib) 150 mg Tablets
Overview: Bracanat contains olaparib, a PARP (poly (ADP-ribose) polymerase) inhibitor used in the treatment of certain cancers, particularly those linked to BRCA1 and BRCA2 gene mutations.
Indications- Ovarian Cancer: For the treatment of adult patients with recurrent ovarian cancer who have received three or more prior lines of chemotherapy.
- Breast Cancer: Indicated for patients with HER2-negative breast cancer and a BRCA mutation who have received chemotherapy.
- Pancreatic Cancer: For the treatment of patients with germline BRCA-mutated metastatic pancreatic cancer who have received at least one prior chemotherapy regimen.
Olaparib inhibits the PARP enzyme, which is involved in repairing DNA damage in cells. This inhibition is particularly effective in cancer cells with BRCA mutations, leading to their inability to repair DNA, which results in cell death.
Dosage and Administration- Dosage: The recommended dose for most indications is typically 300 mg taken orally twice daily. The 150 mg tablet may be used for dose adjustments as needed based on patient tolerability.
- Administration: Tablets can be taken with or without food and should be taken at the same times each day for consistency.
Common side effects may include:
- Nausea
- Fatigue
- Vomiting
- Diarrhea
- Anemia (low red blood cell count)
- Thrombocytopenia (low platelet count)
- MDS/AML Risk: Monitor for signs of myelodysplastic syndromes or acute myeloid leukemia, which have been reported in some patients.
- Hematologic Monitoring: Regular blood counts are recommended to detect anemia and thrombocytopenia.
- Liver Function: Monitor liver enzyme levels, especially if abnormalities are observed.
- Hypersensitivity: Contraindicated in individuals with known allergies to olaparib or any components of the formulation.
Olaparib may interact with:
- CYP3A4 Inhibitors and Inducers: Use caution with medications that affect olaparib metabolism.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and to report any side effects, particularly severe nausea or signs of infection.
- Educate about the importance of regular blood tests to monitor blood counts and liver function.
- Encourage patients to inform their healthcare provider of all medications they are taking to avoid potential interactions.
Bracanat (Olaparib 150 mg Tablets) is an important treatment option for specific cancers associated with BRCA mutations. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Endoxan Cyclophosphamide 50 mg Tablet
Product Price: Rs 85 / VialGet Best Price
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Product Details:
| Strength | 50mg |
| Dose/Strength | 50 mg |
| Packaging Size | 10*10 Tablets |
| Composition | Cyclophosphamide 50 mg |
| Brand | Endoxan 50 mg |
| Manufacturer | Cadila Healthcare Ltd (Zydus) |
| Treatment | Cance |
Endoxan (Cyclophosphamide) 50 mg Tablets
Overview: Endoxan contains cyclophosphamide, an alkylating agent used in chemotherapy. It is effective in treating various types of cancers and certain autoimmune conditions.
Indications- Cancer Treatment: Used for the treatment of various malignancies, including:
- Lymphomas (e.g., Hodgkin’s lymphoma)
- Leukemias (e.g., acute lymphoblastic leukemia)
- Breast cancer
- Ovarian cancer
- Autoimmune Diseases: Sometimes prescribed for conditions such as systemic lupus erythematosus (SLE) and vasculitis.
Cyclophosphamide works by forming covalent bonds with DNA, leading to DNA cross-linking and preventing cancer cell division. This results in cell death, particularly in rapidly dividing cells.
Dosage and Administration- Dosage: The dosing regimen depends on the specific condition being treated and may vary based on individual patient factors. Typical doses range from 1 to 5 mg/kg, administered orally. Always follow the healthcare provider's instructions.
- Administration: Tablets should be taken with a full glass of water. They can be taken with or without food, but consistency in how they are taken is important.
Common side effects may include:
- Nausea and vomiting
- Bone marrow suppression (leading to anemia, leukopenia, and thrombocytopenia)
- Hair loss
- Fatigue
- Increased risk of infections
- Bone Marrow Suppression: Regular monitoring of blood counts is necessary to detect potential complications.
- Infection Risk: Patients are at increased risk for infections due to bone marrow suppression.
- Hydration: Adequate hydration is essential to prevent bladder toxicity.
- Hypersensitivity: Contraindicated in individuals with known allergies to cyclophosphamide or any components of the formulation.
- Severe Bone Marrow Suppression: Should not be used in patients with significant myelosuppression.
Cyclophosphamide may interact with:
- Other Chemotherapeutic Agents: Caution is advised when used with other medications that also affect bone marrow function.
- Anticoagulants: It may affect the efficacy of anticoagulant medications.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and report any side effects, especially signs of infection or unusual bleeding.
- Educate about the importance of regular follow-up appointments and blood tests.
- Encourage patients to maintain hydration and to inform their healthcare provider about all medications they are taking.
Endoxan (Cyclophosphamide 50 mg Tablets) is a valuable medication in the treatment of various cancers and certain autoimmune diseases. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Femistra 1 mg Anastrazole Tablets
Product Price: Rs 275 / BoxGet Best Price
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Product Details:
| Strength | 1 mg |
| Packaging Size | 1*10 Tablets |
| Composition | Anastrozol 1 mg |
| Brand Name | Femistra 1 mg |
| Manufacturer | Zydus Cadila Healthcare Ltd |
| Treatment | Breast cancer |
Femistra (Anastrozole) 1 mg Tablets
Overview: Femistra contains anastrozole, a non-steroidal aromatase inhibitor used primarily in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It helps lower estrogen levels in the body, which can slow or stop the growth of certain types of breast tumors.
Indications- Breast Cancer: Used for the adjuvant treatment of postmenopausal women with hormone receptor-positive early breast cancer and for the treatment of advanced breast cancer.
Anastrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogens in postmenopausal women. By reducing estrogen levels, it helps to slow the growth of estrogen-dependent tumors.
Dosage and Administration- Dosage: The recommended dose is typically 1 mg taken orally once daily.
- Administration: Tablets can be taken with or without food, and it is important to take them at the same time each day for consistency.
Common side effects may include:
- Hot flashes
- Joint pain or stiffness
- Fatigue
- Nausea
- Bone density loss (increased risk of osteoporosis)
- Headache
- Bone Health: Monitor bone mineral density, as long-term use can lead to decreased bone density and increased fracture risk.
- Cardiovascular Risks: Use with caution in patients with a history of cardiovascular disease.
- Allergic Reactions: Be alert for signs of hypersensitivity or allergic reactions.
- Hypersensitivity: Contraindicated in individuals with known allergies to anastrozole or any components of the formulation.
- Pregnancy and Breastfeeding: Not recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant.
Anastrozole may interact with:
- Estrogen-containing Medications: Avoid use with estrogen-containing therapies as they can reduce the effectiveness of anastrozole.
- CYP450 Interactions: Caution is advised when used with medications that affect CYP2A6 and CYP3A4, as they may alter anastrozole metabolism.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and to report any side effects, especially signs of allergic reactions or severe joint pain.
- Educate about the importance of regular follow-up appointments to monitor bone health and overall treatment response.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Femistra (Anastrozole 1 mg Tablets) is an effective treatment option for hormone receptor-positive breast cancer in postmenopausal women. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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250mg Cytomid Fultamide Tablet
Product Price: Rs 130 / StripGet Best Price
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Product Details:
| Strength | 250 mg |
| Packaging Size | 10*10 Tablets |
| Composition | Flutamide 250 mg |
| Brand Name | Cytomod |
| Manufactured By | Cipla Ltd |
| Treatment | Prostate Cancer |
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Herduo Lapatinib 250 mg Tablet
Product Price: Rs 8,000 / BottleGet Best Price
Product Brochure
Product Details:
| Packaging Size | 30 Tablets |
| Strength | 250 mg |
| Pack Size | 30 Tablets |
| Composition | Lapatinib 250 mg |
| Brand | Herduo 250 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Breast Cancer |
Herduo (Lapatinib) 250 mg Tablet
Overview: Herduo contains lapatinib, a targeted therapy used primarily for the treatment of certain types of breast cancer. It is particularly effective in patients with HER2-positive breast cancer and is often used in combination with other therapies.
Indications:
- Breast Cancer: Used for the treatment of advanced or metastatic breast cancer in combination with capecitabine for patients who have progressed on prior therapy, including an anthracycline, a taxane, and trastuzumab.
Mechanism of Action: Lapatinib is a dual tyrosine kinase inhibitor that targets both the epidermal growth factor receptor (EGFR) and HER2 (also known as ERBB2). By inhibiting these pathways, lapatinib helps to slow the growth of cancer cells and prevent them from proliferating.
Dosage and Administration:
- Recommended Dose: The usual dose is 250 mg taken orally once daily.
- Administration: Can be taken with or without food, but it is important to take it consistently regarding meals.
Side Effects: Common side effects may include:
- Diarrhea
- Nausea and vomiting
- Fatigue
- Rash
- Hand-foot syndrome (redness, swelling, and pain on the palms and soles)
Warnings and Precautions:
- Cardiovascular Issues: Monitor for signs of heart problems, as lapatinib can cause decreased left ventricular function.
- Hepatic Impairment: Caution is advised in patients with liver impairment, as dosage adjustments may be necessary.
- Diarrhea Management: Monitor and manage diarrhea, as it can be severe in some patients.
Contraindications:
- Hypersensitivity to lapatinib or any of its components.
- Not recommended during pregnancy and breastfeeding due to potential risks to the fetus or infant.
Drug Interactions: Lapatinib may interact with other medications, particularly those that affect liver enzymes (CYP3A4). Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any side effects, especially severe diarrhea or signs of heart problems.
- Emphasize the importance of regular follow-up appointments for monitoring treatment effectiveness and side effects.
- Encourage discussions about any other medications being taken to avoid potential interactions.
Herduo (Lapatinib) 250 mg Tablets are an important treatment option for HER2-positive breast cancer. Proper dosing, monitoring, and patient education are crucial for maximizing benefits and minimizing risks. Always consult a healthcare provider for personalized treatment advice.
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Stivarga Regorafenib 40 mg Tablet
Product Price: Rs 22,500 / BottleGet Best Price
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Product Details:
| Packaging Size | 28 Tablets |
| Strength | 40 mg |
| Composition | Regorafenib 40 mg |
| Brand | Sitvarga 40 mg |
| Manufacturer | Bayer Plc |
| Treatment | Cancer of Colon & Rectum |
Stivarga (Regorafenib) 40 mg Tablets
Overview: Stivarga contains regorafenib, a multi-kinase inhibitor used for the treatment of various cancers. It targets several pathways involved in tumor growth and angiogenesis (the formation of new blood vessels).
Indications:
- Colorectal Cancer: Used for the treatment of metastatic colorectal cancer in patients who have received prior therapy, including oxaliplatin and irinotecan.
- Gastrointestinal Stromal Tumors (GIST): Indicated for the treatment of GIST in patients who have previously received imatinib and sunitinib.
- Hepatocellular Carcinoma: Used for the treatment of hepatocellular carcinoma in patients who have been previously treated with sorafenib.
Mechanism of Action: Regorafenib inhibits multiple kinases involved in tumor growth, including VEGFR (vascular endothelial growth factor receptor), PDGFR (platelet-derived growth factor receptor), and BRAF. By inhibiting these pathways, regorafenib can slow tumor progression and reduce blood supply to the tumor.
Dosage and Administration:
- Recommended Dose: The typical dose is 160 mg taken orally once daily for the first 21 days of a 28-day cycle. However, the specific dosage may vary based on individual patient factors and treatment response.
- Administration: Should be taken with food, and the tablets should be swallowed whole; do not crush or chew.
Side Effects: Common side effects may include:
- Fatigue
- Diarrhea
- Hand-foot syndrome (redness, swelling, and discomfort on the palms and soles)
- Hypertension (increased blood pressure)
- Rash
Warnings and Precautions:
- Cardiovascular Monitoring: Monitor blood pressure and assess for signs of cardiac issues, as regorafenib can cause hypertension.
- Liver Function: Liver function tests should be conducted regularly, as regorafenib may affect liver function.
- Gastrointestinal Perforation: There is a risk of gastrointestinal perforation; patients should be advised to report severe abdominal pain.
Contraindications:
- Hypersensitivity to regorafenib or any components of the formulation.
- Pregnancy and breastfeeding are not recommended due to potential risks to the fetus or infant.
Drug Interactions: Regorafenib may interact with other medications, especially those affecting liver enzymes (CYP3A4). Patients should inform their healthcare provider about all medications they are taking.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Instruct patients to take the medication as prescribed and to report any side effects, especially severe gastrointestinal symptoms or changes in blood pressure.
- Emphasize the importance of regular follow-up appointments for monitoring treatment effectiveness and side effects.
- Discuss potential lifestyle changes, including dietary adjustments to manage side effects.
Stivarga (Regorafenib) 40 mg Tablets are an important treatment option for various cancers, particularly metastatic colorectal cancer and GIST. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment advice.
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Alkacel 2 mg Tablet
Product Price: Rs 600 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 2 mg |
| Packaging Size | 25 Tablet |
| Composition | Melphalan 2 mg |
| Brand Name | Alkacel 2 mg |
| Manufactured By | Celon Laboratories Ltd |
| Treatment | Ovarian cancer |
Alkacel (Alfacalcidol) 2 mg Tablets
Overview: Alkacel contains alfacalcidol, a synthetic form of vitamin D. It is used to manage calcium and phosphate metabolism in the body, especially in patients with certain kidney conditions.
Indications:
- Bone Disorders: Often prescribed for patients with chronic kidney disease to help prevent bone disease associated with renal osteodystrophy.
- Hypoparathyroidism: Used to treat conditions where there is low parathyroid hormone leading to low calcium levels.
Mechanism of Action: Alfacalcidol is converted in the body to calcitriol, the active form of vitamin D. It increases intestinal absorption of calcium and phosphate, promotes bone mineralization, and helps maintain normal serum calcium levels.
Dosage and Administration:
- Recommended Dose: The dosage may vary based on the condition being treated. A common starting dose is 1 to 2 mg per day, but specific recommendations should be made by a healthcare provider.
- Administration: Can be taken with or without food. It’s important to follow the prescribed dosing schedule.
Side Effects: Common side effects may include:
- Hypercalcemia (high calcium levels)
- Nausea
- Vomiting
- Constipation
- Weakness or fatigue
Warnings and Precautions:
- Calcium Levels: Regular monitoring of serum calcium and phosphate levels is essential to avoid complications associated with hypercalcemia.
- Kidney Function: Patients with kidney impairment should be closely monitored for signs of vitamin D toxicity.
Contraindications:
- Hypersensitivity to alfacalcidol or any components of the formulation.
- Hypercalcemia or conditions that lead to elevated calcium levels.
Drug Interactions: Alfacalcidol may interact with other medications that affect calcium metabolism. Patients should inform their healthcare provider about all medications and supplements they are taking.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any symptoms of high calcium levels, such as nausea, vomiting, or unusual fatigue.
- Emphasize the importance of regular blood tests to monitor calcium and phosphate levels.
- Discuss dietary considerations related to calcium intake.
Alkacel (Alfacalcidol) 2 mg Tablets are an important treatment for managing calcium and phosphate metabolism, especially in patients with renal conditions. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment recommendations.
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Erlocip 150 mg Tablet
Product Price: Rs 2,000 / BottleGet Best Price
Product Brochure
Product Details:
| Dose/Strength | 150 mg |
| Pack Size | 30 Tablet in 1 Bottle |
| Composition | Erlotinib 150 |
| Brand Name | Erlocip 150 mg |
| Manufactured By | Cipla Ltd |
| Treatment | Non-small cell Lung Cancer |
Erlocip (Erlotinib) 150 mg Tablets
Overview: Erlocip contains erlotinib, an epidermal growth factor receptor (EGFR) inhibitor used primarily in the treatment of certain types of cancer, particularly non-small cell lung cancer (NSCLC) and pancreatic cancer.
Indications:
- Non-Small Cell Lung Cancer (NSCLC): Used for the treatment of patients with locally advanced or metastatic NSCLC with EGFR mutations.
- Pancreatic Cancer: Used in combination with gemcitabine for the treatment of advanced pancreatic cancer.
Mechanism of Action: Erlotinib selectively inhibits the EGFR tyrosine kinase, preventing the phosphorylation and activation of downstream signaling pathways that promote cell growth and division. This action helps to slow down or stop the growth of cancer cells.
Dosage and Administration:
- Recommended Dose: The usual starting dose is 150 mg taken orally once daily.
- Administration: Can be taken with or without food. It is important to take it consistently, either always with food or always without.
Side Effects: Common side effects may include:
- Diarrhea
- Skin rash and acne
- Nausea
- Fatigue
- Decreased appetite
- Dry skin or itching
Warnings and Precautions:
- Pulmonary Toxicity: Monitor for signs of interstitial lung disease (ILD), which can be serious or fatal.
- Skin Reactions: Dermatologic toxicity can occur; patients should be monitored for rash and skin infections.
- Liver Function: Liver function tests should be monitored, as elevations in liver enzymes may occur.
Contraindications:
- Hypersensitivity to erlotinib or any components of the formulation.
- Not recommended during pregnancy or breastfeeding due to potential risks.
Drug Interactions: Erlotinib may interact with medications that affect liver enzymes (CYP3A4). Patients should inform their healthcare provider about all medications and supplements they are taking.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any side effects, particularly severe skin reactions or respiratory symptoms.
- Emphasize the importance of regular follow-up appointments to monitor treatment effectiveness and any potential side effects.
- Discuss the importance of maintaining hydration, especially if experiencing diarrhea.
Erlocip (Erlotinib) 150 mg Tablets are an important treatment option for specific cancers, particularly NSCLC and pancreatic cancer. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment recommendations.
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Tykerb Lapatinib 250 mg Tablets
Product Price: Rs 20,500 / BottleGet Best Price
Product Brochure
Product Details:
| Packaging Size | 30 Tablets |
| Strength | 250 mg |
| Pack Size | 30 Tablets in 1 Bottle |
| Composition | Lapatinib 250 mg |
| Manufacturer | Glaxo SmithKline Pharmaceuticals Ltd |
| Treatment | Breast Cancer |
Tykerb (Lapatinib) 250 mg Tablets
Overview: Tykerb contains lapatinib, a targeted therapy primarily used for treating HER2-positive breast cancer. It works by inhibiting specific proteins that promote cancer cell growth.
Indications:
- Breast Cancer: Indicated for the treatment of advanced or metastatic breast cancer in combination with capecitabine for patients who have progressed after previous therapy, including an anthracycline, a taxane, and trastuzumab.
Mechanism of Action: Lapatinib is a dual tyrosine kinase inhibitor targeting both the epidermal growth factor receptor (EGFR) and HER2 (ERBB2). By blocking these receptors, lapatinib helps to inhibit tumor growth and spread.
Dosage and Administration:
- Recommended Dose: The standard dose is 250 mg taken orally once daily.
- Administration: It can be taken with or without food, but consistency regarding meals is recommended for optimal absorption.
Side Effects: Common side effects may include:
- Diarrhea
- Nausea and vomiting
- Fatigue
- Rash
- Hand-foot syndrome (redness, swelling, and discomfort on palms and soles)
Warnings and Precautions:
- Cardiac Monitoring: Patients should be monitored for potential heart issues, as lapatinib can affect cardiac function.
- Liver Function: Caution is advised in patients with hepatic impairment; liver function tests should be monitored.
- Diarrhea Management: Severe diarrhea may occur; patients should be advised to report it immediately.
Contraindications:
- Hypersensitivity to lapatinib or any of its components.
- Not recommended during pregnancy or breastfeeding due to potential risks.
Drug Interactions: Lapatinib may interact with other medications, particularly those affecting CYP3A4 enzymes. Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Instruct patients to take the medication as prescribed and to report any side effects, particularly severe diarrhea or cardiac symptoms.
- Highlight the importance of regular follow-up appointments to monitor treatment effectiveness and any side effects.
- Discuss any other medications being taken to prevent potential interactions.
Tykerb (Lapatinib) 250 mg Tablets are an essential treatment for HER2-positive breast cancer. Proper dosing, monitoring, and patient education are crucial for maximizing benefits and minimizing risks. Always consult a healthcare provider for personalized treatment recommendations.
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Evermil Everolimus 10 mg Tablets
Product Price: Rs 8,000 / BoxGet Best Price
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Product Details:
| Strength | 10 mg |
| Packaging Size | 1*10 Tablet ( 10 Tablets ) |
| Composition | Everolimus 10 mg |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Treatment | Prevention of organ rejection in transplant patients |
Evermil (Everolimus) 10 mg Tablets
Overview: Evermil contains everolimus, an mTOR (mammalian target of rapamycin) inhibitor that is used primarily for the treatment of certain cancers and to prevent organ rejection in transplant patients. It interferes with cell growth and proliferation, particularly in cancer cells.
Indications:
- Cancer Treatment:
- Advanced renal cell carcinoma.
- Neuroendocrine tumors (non-functional) of pancreatic origin.
- Hormone receptor-positive, HER2-negative breast cancer after prior endocrine therapy.
- Organ Transplantation: Used to prevent organ rejection in kidney transplant patients.
Mechanism of Action: Everolimus inhibits the mTOR pathway, which plays a critical role in regulating cell growth, proliferation, and survival. By blocking this pathway, everolimus slows down or stops the growth of tumors and modulates the immune response.
Dosage and Administration:
- Recommended Dose: Typically, the starting dose is 10 mg taken orally once daily, but this can vary based on the specific condition and the patient's response.
- Administration: It can be taken with or without food, but consistency in how it is taken relative to meals is advised.
Side Effects: Common side effects may include:
- Mouth ulcers
- Nausea and vomiting
- Diarrhea
- Fatigue
- Rash
- Increased risk of infections
Warnings and Precautions:
- Infection Risk: Due to immunosuppressive effects, there is a higher risk of infections.
- Liver Function: Regular monitoring of liver function tests is necessary, as abnormalities may occur.
- Blood Sugar Levels: May cause hyperglycemia; patients with diabetes should monitor their blood glucose levels closely.
Contraindications:
- Hypersensitivity to everolimus or any components of the formulation.
- Not recommended during pregnancy or breastfeeding due to potential risks.
Drug Interactions: Everolimus can interact with various medications, particularly those that affect CYP3A4 enzymes. Patients should disclose all medications and supplements they are taking to their healthcare provider.
Storage Instructions: Store at room temperature, protected from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Instruct patients to take the medication exactly as prescribed and to report any side effects, especially signs of infection or unusual bleeding.
- Emphasize the importance of regular follow-up appointments for monitoring health.
- Discuss lifestyle considerations, including diet and exercise, particularly for those with diabetes.
Evermil (Everolimus) 10 mg Tablets are an important treatment option for certain cancers and in organ transplantation. Adhering to prescribed dosing, monitoring for side effects, and maintaining open communication with healthcare providers are essential for maximizing treatment effectiveness and safety. Always consult a healthcare provider for personalized treatment recommendations.
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Evermil Everolimus 5 mg Tablet
Product Price: Rs 4,500 / StripeGet Best Price
Product Brochure
Product Details:
| Strength | 5 mg |
| Packaging Size | 1*10 Tablet ( 10 Tablets ) |
| Composition | Everolimus 5 mg |
| Brand | Evermil 5 mg |
| Manufacturer | Glenmark Pharmaceuticals Ltd |
| Treatment | Prevention of Organ Rejection in Transplant Patients |
Evermil (Everolimus) 5 mg Tablet
Overview: Evermil contains everolimus, an mTOR (mammalian target of rapamycin) inhibitor used primarily in the treatment of certain types of cancer and in organ transplantation. It works by inhibiting cell growth and proliferation, particularly in cancer cells.
Indications:
- Cancer Treatment: Used in combination with other therapies for advanced renal cell carcinoma, neuroendocrine tumors, and breast cancer (HR-positive, HER2-negative) after prior endocrine therapy.
- Organ Transplantation: Used to prevent organ rejection in patients receiving a kidney transplant.
Mechanism of Action: Everolimus inhibits the mTOR pathway, which is crucial for cell growth and metabolism. By blocking this pathway, everolimus helps to slow down or stop the growth of cancer cells and reduces the immune response to transplanted organs.
Dosage and Administration:
- Recommended Dose: Typically, the starting dose is 5 mg taken orally once daily. Dosage may vary based on the specific condition being treated and the patient’s response.
- Administration: Can be taken with or without food, but it’s best to take it consistently with respect to meals.
Side Effects: Common side effects may include:
- Mouth ulcers
- Nausea
- Diarrhea
- Fatigue
- Rash
- Increased risk of infections
Warnings and Precautions:
- Infection Risk: Everolimus can increase the risk of infections due to its immunosuppressive effects.
- Liver Function: Monitor liver function tests regularly, as abnormalities can occur.
- Blood Sugar Levels: May cause hyperglycemia; monitor blood glucose levels in patients with diabetes or those at risk.
Contraindications:
- Hypersensitivity to everolimus or any components of the formulation.
- Pregnancy and breastfeeding due to potential risks.
Drug Interactions: Everolimus may interact with other medications, particularly those affecting liver enzymes (CYP3A4). Patients should inform their healthcare provider about all medications they are taking.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any side effects, especially signs of infection or unusual bruising/bleeding.
- Educate about the importance of regular follow-up appointments to monitor health status.
- Encourage patients to maintain a healthy lifestyle and discuss any dietary changes with their healthcare provider.
Evermil (Everolimus) 5 mg Tablets are an important treatment option for certain cancers and in organ transplantation. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment advice.
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Cytotam 20 mg Tablets
Product Price: Rs 75 / StripeGet Best Price
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Product Details:
| Strength | 20 mg |
| Packaging Size | 10*10 Tablet |
| Composition | Tamoxifen 20 mg |
| Brand | Cytotam 20 mg |
| Manufacturer | Cipla Ltd |
| Treatment | Breast cancer |
Cytotam (Tamoxifen) 20 mg Tablets
Overview: Cytotam contains tamoxifen, a selective estrogen receptor modulator (SERM) primarily used in the treatment of hormone receptor-positive breast cancer. It works by blocking the effects of estrogen in breast tissue, which can help slow or stop the growth of certain tumors.
Indications:
- Breast Cancer Treatment: Used in the adjuvant treatment of estrogen receptor-positive breast cancer in women and men.
- Breast Cancer Prevention: May be indicated for women at high risk of developing breast cancer.
Mechanism of Action: Tamoxifen competes with estrogen for binding to estrogen receptors on breast cancer cells, inhibiting estrogen's effects and thereby slowing tumor growth.
Dosage and Administration:
- Recommended Dose: The typical dosage is 20 mg taken orally once daily, although the specific dose may vary based on individual treatment plans.
- Administration: Can be taken with or without food. Consistency in timing is recommended for optimal results.
Side Effects: Common side effects may include:
- Hot flashes
- Nausea
- Fatigue
- Vaginal discharge or bleeding
- Risk of blood clots (thrombosis)
Warnings and Precautions:
- Thromboembolic Events: There is an increased risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism.
- Endometrial Cancer: Long-term use may raise the risk of endometrial cancer; patients should be monitored for unusual vaginal bleeding.
- Liver Function: Regular monitoring of liver function is advised, as tamoxifen can impact liver health.
Contraindications:
- Hypersensitivity to tamoxifen or any of its components.
- History of thromboembolic disorders.
- Not recommended during pregnancy or breastfeeding.
Drug Interactions: Tamoxifen may interact with other medications, particularly those that influence liver enzymes (CYP2D6). Patients should disclose all medications and supplements they are taking to their healthcare provider.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any side effects, especially signs of blood clots (e.g., swelling, pain in the legs, shortness of breath).
- Emphasize the importance of regular follow-up appointments for monitoring treatment effectiveness and side effects.
- Discuss lifestyle changes that may help manage side effects.
Cytotam (Tamoxifen) 20 mg Tablets are an essential treatment option for hormone receptor-positive breast cancer. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment recommendations.
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Ramiven 50 mg Tablets Abemaciclib
Product Price: Rs 25,500 / BoxGet Best Price
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Product Details:
| Strength | 50 mg |
| Packaging Size | 14 Tablets |
| Composition | Abemaciclib 50 mg |
| Brand | Ramiven 50 mg |
| Manufacturer | Eli Lilly and Company India Pvt Ltd |
| Treatment | Metastatic Breast Cancer |
Ramiven (Abemaciclib) 50 mg Tablets
Overview: Ramiven contains abemaciclib, a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6) used primarily in the treatment of hormone receptor-positive, HER2-negative breast cancer. It is often prescribed for patients with advanced or metastatic breast cancer, particularly in combination with endocrine therapy.
Indications- Breast Cancer: Used for the treatment of HR-positive, HER2-negative breast cancer in:
- Patients with advanced or metastatic disease.
- Patients who have received prior endocrine therapy.
Abemaciclib works by inhibiting CDK4 and CDK6, which are key regulators of the cell cycle. By blocking these kinases, abemaciclib helps to halt the progression of cancer cells through the cell cycle, thereby slowing down or stopping tumor growth.
Dosage and Administration- Dosage: The recommended starting dose is typically 150 mg taken twice daily, but the 50 mg tablets may be used for dose adjustments based on individual patient needs and tolerability.
- Administration: Tablets should be taken orally, with or without food. Consistency in timing is important, so it’s best to take them at the same times each day.
Common side effects may include:
- Diarrhea
- Neutropenia (low white blood cell count)
- Fatigue
- Nausea
- Abdominal pain
- Liver enzyme elevations
- Neutropenia: Regular monitoring of blood counts is essential due to the risk of infections.
- Liver Function: Liver function tests should be conducted before and during treatment, as dose adjustments may be necessary if liver enzymes are elevated.
- Diarrhea Management: Patients should be monitored for diarrhea, which can be a common and sometimes severe side effect.
- Hypersensitivity: Contraindicated in individuals with known allergies to abemaciclib or any components of the formulation.
Abemaciclib may interact with:
- CYP3A4 Inhibitors and Inducers: These can alter abemaciclib levels, necessitating careful monitoring and possible dose adjustments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication consistently and to report any signs of infection or severe gastrointestinal side effects.
- Educate about the importance of hydration and managing diarrhea.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Ramiven (Abemaciclib 50 mg Tablets) is an important treatment option for specific types of breast cancer. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Megestrol Megace 160 mg Tablet
Product Price: Rs 350 / BoxGet Best Price
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Product Details:
| Strength | 160 mg |
| Packaging Size | 30 Tablet |
| Composition | Megestrol 160 mg |
| Brand | Megace 160 mg |
| Manufactured By | Aureate Healthcare Pvt Ltd |
| Treatment | Breast cancer |
Megace (Megestrol Acetate) 160 mg Tablets
Overview: Megace contains megestrol acetate, a synthetic progestin that is primarily used to treat conditions associated with hormone imbalances. It is commonly prescribed for appetite stimulation and weight gain in patients with cancer or AIDS, as well as for certain cancers.
Indications- Anorexia/Cachexia: To increase appetite and promote weight gain in patients experiencing weight loss due to cancer or AIDS.
- Endometrial Carcinoma: As part of the treatment regimen for advanced or recurrent endometrial carcinoma.
Megestrol acetate acts by binding to progesterone receptors, leading to effects such as appetite stimulation and modulation of hormonal activity. This action helps improve appetite and can lead to weight gain.
Dosage and Administration- Dosage: The typical starting dose for appetite stimulation is often 160 mg taken once daily. Dosing may vary based on the specific condition being treated and the patient's response.
- Administration: Tablets can be taken orally, with or without food. It is advisable to take them at the same time each day for consistency.
Common side effects may include:
- Weight gain
- Edema (swelling)
- Fatigue
- Nausea
- Insomnia
- Increased sweating
- Hormonal Effects: Monitor for signs of thromboembolic events and changes in menstrual cycles due to hormonal effects.
- Liver Function: Use with caution in patients with liver impairment, as megestrol is metabolized by the liver.
- Diabetes: May affect glucose metabolism; monitoring blood sugar levels in diabetic patients is advisable.
- Hypersensitivity: Contraindicated in individuals with known allergies to megestrol acetate or any components of the formulation.
- Pregnancy: Not recommended during pregnancy due to potential risks to the fetus.
Megestrol may interact with:
- Anticoagulants: May affect the metabolism of anticoagulants like warfarin, requiring careful monitoring of INR levels.
- Other Hormonal Therapies: Caution is advised when used in conjunction with other hormone-based treatments.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and to report any side effects, particularly weight gain or hormonal changes.
- Educate about the importance of regular follow-up appointments to monitor health status.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Megace (Megestrol Acetate 160 mg Tablets) is an effective treatment option for managing appetite and weight loss in specific patient populations and for certain cancers. Proper dosing, monitoring, and patient education are essential for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Abemaciclib Verzenio 150 mg Tablets
Product Price: Rs 22,500 / BoxGet Best Price
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Product Details:
| Strength | 150 mg |
| Packaging Size | 14 Tablet |
| Composition | Abemaciclib 150 mg |
| Brand | Verzenio 150 mg |
| Manufacturer | Eli Lilly and Company India Pvt Ltd |
| Treatment | Metastatic Breast Cancer |
Verzenio (Abemaciclib) 150 mg Tablets
Overview: Verzenio contains abemaciclib, a selective CDK4/6 (cyclin-dependent kinase 4 and 6) inhibitor used primarily in the treatment of certain types of breast cancer. It helps to slow down the growth of cancer cells by interfering with the cell cycle.
Indications- Hormone Receptor-Positive, HER2-Negative Breast Cancer: Used in combination with an aromatase inhibitor or fulvestrant for the treatment of adults with hormone receptor-positive, HER2-negative breast cancer, either as initial endocrine-based therapy or after disease progression following endocrine therapy.
Abemaciclib selectively inhibits CDK4 and CDK6, which play a crucial role in cell cycle progression. By blocking these kinases, abemaciclib disrupts the cancer cell cycle, leading to cell cycle arrest and reduced proliferation of cancer cells.
Dosage and Administration- Dosage: The recommended dose is typically 150 mg taken orally twice daily. Depending on the patient's response and tolerance, dosage adjustments may be necessary.
- Administration: Tablets can be taken with or without food. It's important to take them at the same times each day for consistency.
Common side effects may include:
- Diarrhea
- Fatigue
- Nausea
- Abdominal pain
- Decreased appetite
- Neutropenia (low white blood cell count)
- Neutropenia: Regular monitoring of blood counts is essential, as neutropenia can increase the risk of infections.
- Liver Function: Liver enzyme levels should be monitored, especially in patients with liver impairment or those taking medications that affect liver function.
- Diarrhea Management: Patients should be advised on managing diarrhea, as it can be a common side effect.
- Hypersensitivity: Contraindicated in individuals with known allergies to abemaciclib or any components of the formulation.
Abemaciclib may interact with:
- CYP3A4 Inhibitors and Inducers: Use caution with medications that may affect the metabolism of abemaciclib, as this can alter its effectiveness and safety.
Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to take the medication as prescribed and to report any side effects, especially severe diarrhea or signs of infection.
- Educate about the importance of regular blood tests to monitor for neutropenia.
- Encourage patients to inform their healthcare provider about all medications they are taking to avoid potential interactions.
Verzenio (Abemaciclib 150 mg Tablets) is a valuable treatment option for hormone receptor-positive, HER2-negative breast cancer. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized guidance regarding treatment.
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Rucaparib Lucaparib 300 mg Tablets
Product Price: Rs 28,500 / BottleGet Best Price
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Product Details:
| Strength | 300 mg |
| Pack Size | 60 Tablets in 1 Bottle |
| Composition | Rucaparib 300 mg |
| Brand | Lucaparib 300 mg |
| Manufacturer | Lupin |
| Treatment | Prostate cancer |
Rucaparib (Lucaparib) 300 mg Tablets
Overview: Rucaparib, marketed under the brand name Lucaparib, is a PARP (poly ADP-ribose polymerase) inhibitor used primarily in the treatment of certain types of cancer, particularly those associated with BRCA mutations.
Indications:
- Ovarian Cancer: Used for the treatment of patients with recurrent ovarian cancer who have been treated with two or more prior therapies and who have homologous recombination repair (HRR) deficiency, including BRCA mutations.
- Prostate Cancer: May be used for certain patients with metastatic castration-resistant prostate cancer and BRCA mutations.
Mechanism of Action: Rucaparib inhibits the PARP enzyme, which plays a key role in repairing DNA damage. By blocking this enzyme, rucaparib leads to the accumulation of DNA damage in cancer cells, ultimately resulting in cell death, particularly in cells deficient in homologous recombination repair.
Dosage and Administration:
- Recommended Dose: The typical starting dose is 600 mg (300 mg taken twice daily). However, the specific dosage may vary based on individual patient factors and response.
- Administration: Can be taken with or without food, but it’s advisable to take it at the same time each day for consistency.
Side Effects: Common side effects may include:
- Nausea and vomiting
- Fatigue
- Anemia
- Increased liver enzymes
- Diarrhea
Warnings and Precautions:
- Myelodysplastic Syndrome (MDS)/Acute Myeloid Leukemia (AML): There is a risk of MDS or AML in patients receiving rucaparib. Regular monitoring is recommended.
- Liver Function: Liver function tests should be monitored due to potential elevations in liver enzymes.
- Pregnancy and Breastfeeding: Not recommended due to potential risks to the fetus or infant.
Contraindications:
- Hypersensitivity to rucaparib or any of its components.
- Pregnancy and breastfeeding.
Drug Interactions: Rucaparib may interact with other medications. Patients should inform their healthcare provider about all medications and supplements they are taking to avoid potential interactions.
Storage Instructions: Store at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to take the medication as prescribed and to report any side effects, especially signs of anemia (fatigue, pallor).
- Emphasize the importance of regular follow-up appointments and blood tests to monitor liver function and blood counts.
- Discuss potential risks during pregnancy and the importance of effective contraception during treatment.
Rucaparib (Lucaparib) 300 mg Tablets are an important treatment option for certain cancers with specific genetic backgrounds. Proper dosing, monitoring, and patient education are crucial for maximizing therapeutic benefits and minimizing risks. Always consult a healthcare provider for personalized treatment advice.
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