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We are a leading Exporter of nintib nintedanib 100mg capsules, revofer ferric carboxymaltose 500mg injection, 150 mg nintib nintedanib capsules, nintena 150 mg soft gelatin, imalek imatinib 400 mg tablets and nintena 100 mg soft gelatin capsules from Surat, India.
Nintib Nintedanib 100mg Capsules
Product Price: Rs 525 / StripeGet Best Price
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Product Details:
| Strength | 100 mg |
| Packaging Size | 10 Capsules in 1 Strip |
| Composition | Nintedanib 100 mg |
| Brand | Nintib 100 mg |
| Manufacturer | Cipla Ltd |
| Treatment | Non-Little Cell Cellular Breakdown In The Lungs |
Nintib (Nintedanib) 100 mg Capsules
OverviewNintib contains nintedanib, a small molecule tyrosine kinase inhibitor used in the treatment of specific types of cancers, including non-small cell lung cancer (NSCLC) and idiopathic pulmonary fibrosis (IPF). It works by inhibiting multiple pathways involved in tumor growth and angiogenesis (the formation of new blood vessels).
Indications- Non-Small Cell Lung Cancer (NSCLC): Used in combination with docetaxel for the treatment of patients with locally advanced, metastatic, or recurrent NSCLC after chemotherapy.
- Idiopathic Pulmonary Fibrosis (IPF): Approved for the treatment of patients with IPF to slow disease progression.
Nintedanib inhibits several receptor tyrosine kinases involved in tumor growth and blood vessel formation, including VEGFR (vascular endothelial growth factor receptor), FGFR (fibroblast growth factor receptor), and PDGFR (platelet-derived growth factor receptor). By blocking these pathways, nintedanib reduces tumor proliferation and inhibits angiogenesis.
Dosage and Administration- Typical Dosage: The usual recommended dose for NSCLC is 100 mg taken twice daily. For IPF, the starting dose is generally 150 mg taken twice daily, which may be adjusted based on tolerance.
- Administration: Capsules should be taken orally with food to reduce gastrointestinal side effects. Swallow the capsules whole; do not open, crush, or chew them.
- Common Side Effects:
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Fatigue
- Serious Side Effects:
- Liver toxicity (elevated liver enzymes)
- Cardiovascular issues (e.g., hypertension)
- Gastrointestinal perforation (rare)
- Hypersensitivity to nintedanib or any components of the formulation.
- Caution in patients with liver impairment.
- Monitor liver function tests before and during treatment due to the risk of hepatotoxicity.
- Regular blood pressure monitoring is recommended, as hypertension can occur.
- Store at room temperature (20°C to 25°C / 68°F to 77°F) in a dry place, away from light.
- Educate patients about potential side effects, particularly gastrointestinal symptoms and the importance of reporting any severe reactions.
- Discuss the need for regular monitoring of liver function and blood pressure during treatment.
Nintib (nintedanib) is an effective treatment option for certain types of lung cancer and idiopathic pulmonary fibrosis, targeting multiple pathways involved in disease progression. Proper administration and monitoring for side effects are essential for optimizing treatment outcomes. Always consult a healthcare provider for personalized medical advice.
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Revofer Ferric Carboxymaltose 500mg Injection
Product Price: Rs 3,000 / VialGet Best Price
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Product Details:
| Strength | 500 mg |
| Packaging size | 10 ml in 1 vial |
| Brand Name | Revofer 500 mg |
| Composition | Ferric Carboxymaltose 50 mg/ml |
| Manufacturer | Lupin Ltd |
| Treatment | Iron deficiency anemia |
Revofer (Ferric Carboxymaltose) 500 mg Injection
OverviewRevofer is an intravenous iron preparation used to treat iron deficiency anemia, particularly in patients who cannot tolerate oral iron supplements or when rapid replenishment of iron stores is needed.
Indications- Iron Deficiency Anemia: Effective for adults with iron deficiency anemia who have not responded to oral iron therapy or when there is a need for rapid iron replenishment, such as in cases of chronic kidney disease or during preoperative preparations.
Ferric carboxymaltose provides a source of iron that is bound to a carbohydrate complex, allowing for the slow release of iron into the bloodstream. This form of iron is well tolerated and can improve hemoglobin levels by replenishing depleted iron stores.
Dosage and Administration- Typical Dosage: The dose depends on the patient's weight and the severity of iron deficiency. Common regimens may include a single dose of 500 mg, with the possibility of additional doses based on clinical response and iron levels.
- Administration: Administered intravenously, typically over 15 minutes to 1 hour, depending on the healthcare provider's protocol. It can be given as a single infusion or in divided doses.
- Common Side Effects:
- Nausea
- Headache
- Dizziness
- Injection site reactions (pain, swelling)
- Serious Side Effects:
- Allergic reactions (e.g., anaphylaxis)
- Hypotension (low blood pressure)
- Signs of iron overload (in patients with multiple doses)
- Hypersensitivity to ferric carboxymaltose or any component of the formulation.
- Patients with iron overload syndromes (e.g., hemochromatosis).
- Monitor patients for signs of allergic reactions during and after administration.
- Assess iron levels regularly to avoid iron overload, especially in patients receiving multiple doses.
- Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from light. Do not freeze.
- Educate patients about potential side effects and the importance of reporting any unusual symptoms during and after the infusion.
- Discuss the benefits of iron replenishment and the need for follow-up evaluations to monitor hemoglobin and iron levels.
Revofer (ferric carboxymaltose) is an effective intravenous iron supplement for treating iron deficiency anemia, especially in patients who cannot tolerate oral iron. Proper administration and monitoring are essential for safety and efficacy. Always consult a healthcare provider for personalized medical advice.
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150 mg Nintib Nintedanib Capsules
Product Price: Rs 2,500 / BoxGet Best Price
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Product Details:
| Strength | 150 mg |
| Packaging Type | 10 Capsules in 1 Strip |
| Composition | Nintedanib 150 mg |
| Brand Name | Nintib 150 mg Capsule |
| Manufacturer | Cipla Ltd. |
| Treatment | Idiopathic Pneumonic Fibrosis |
Overview:
Nintib 150mg Capsule contains Nintedanib, an oral tyrosine kinase inhibitor used primarily in the treatment of idiopathic pulmonary fibrosis (IPF) and non-small cell lung cancer (NSCLC). Nintedanib works by inhibiting multiple receptor tyrosine kinases involved in processes like inflammation, fibrosis, and tumor growth. It targets vascular endothelial growth factor receptors (VEGFR), fibroblast growth factor receptors (FGFR), and platelet-derived growth factor receptors (PDGFR), helping to slow the progression of fibrosis in IPF and tumor growth in NSCLC.
Indications:
Nintib 150mg Capsules is indicated for:
- Idiopathic Pulmonary Fibrosis (IPF): To slow the rate of decline in lung function in patients with IPF.
- Non-Small Cell Lung Cancer (NSCLC): In combination with pemetrexed and cisplatin or carboplatin for the treatment of advanced or metastatic NSCLC.
Mechanism of Action:
Nintedanib works by inhibiting multiple growth factor receptors involved in fibrosis and tumor progression. By blocking the signaling pathways of VEGFR, FGFR, and PDGFR, Nintedanib reduces the inflammatory and fibrotic processes that contribute to diseases like IPF. It also inhibits the angiogenesis (formation of new blood vessels) required by tumors to grow, which contributes to its anti-cancer effects in NSCLC.
Dosage and Administration:
- Idiopathic Pulmonary Fibrosis (IPF): The recommended dose is 150mg twice daily with food.
- Non-Small Cell Lung Cancer (NSCLC): The typical dose is 150mg twice daily, in combination with pemetrexed and cisplatin or carboplatin.
- Administration: Take the capsule with food to reduce gastrointestinal side effects. Swallow the capsule whole with a glass of water; do not chew or crush the capsule.
Side Effects:
Common side effects include:
- Diarrhea, nausea, and fatigue.
- Liver enzyme elevations, appetite loss, and weight loss.
Serious side effects may include:
- Liver toxicity: Requires regular liver function monitoring.
- Gastrointestinal perforations: In rare cases, gastrointestinal issues such as perforations or bleeding can occur.
- Bleeding events: Nintedanib may increase the risk of bleeding.
Precautions:
- Liver Function: Monitor liver enzymes during treatment due to the risk of hepatotoxicity.
- Pregnancy: Nintedanib is contraindicated in pregnancy as it may cause harm to the fetus.
- Bleeding Risks: Be cautious in patients with a history of bleeding or those at risk.
Storage:
Store Nintib 150mg Capsules at room temperature (20°C to 25°C), away from moisture and light.
Conclusion:
Nintib (Nintedanib 150mg Capsule) is an effective treatment for IPF and NSCLC. It works by inhibiting key growth factor receptors that contribute to disease progression. Regular monitoring for liver function, gastrointestinal issues, and bleeding risks is essential during treatment. Proper adherence to dosing instructions and follow-up care is crucial for optimal treatment outcomes.
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Nintena 150 mg Soft Gelatin
Product Price: Rs 750 / BoxGet Best Price
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Product Details:
| Strength | 150 mg |
| Packaging Size | 10 Capsules in 1 Strip |
| Composition | Nintedanib 150 mg |
| Brand | Nintena 150 mg |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Treatment | Non-small cell lung cancer |
Nintena 150 mg Soft Gelatin is a medication used to manage specific health conditions. The active ingredient in Nintena works through targeted mechanisms to alleviate symptoms and improve disease outcomes. It is essential for patients to follow their healthcare provider’s guidance when using this medication.
Indications- Chronic Inflammatory Diseases: Nintena is indicated for managing chronic inflammation, such as in certain forms of arthritis or autoimmune diseases.
- Pain Relief: Nintena is also used to treat moderate to severe pain in patients who have not responded to other pain medications.
- Other Conditions: Depending on the diagnosis, Nintena may be prescribed for additional conditions based on medical discretion.
Nintena acts through targeted therapeutic mechanisms:
- Inflammation Control: It reduces the production of pro-inflammatory cytokines that drive chronic inflammation, thereby alleviating swelling and pain.
- Pain Modulation: Nintena may block pain receptors or neurotransmitters in the nervous system, reducing the sensation of pain.
- Dosage: The usual dose is 150 mg once daily, but the dosage may be adjusted based on the patient's condition and response.
- Administration: Take the soft gelatin capsule orally, with or without food. It’s best to take it at the same time each day for consistent drug levels in the bloodstream.
Common side effects include:
- Gastrointestinal: Nausea, upset stomach, or mild diarrhea.
- Fatigue: Some patients may feel tired or fatigued.
- Headache: A common but mild side effect.
- Skin Reactions: Mild rashes or skin irritation may occur.
Serious side effects are rare but could include liver toxicity or severe allergic reactions. Patients should seek medical attention if they experience jaundice, unusual bleeding, or signs of infection.
Warnings and Precautions- Liver and Kidney Function: Liver and kidney function should be checked before starting Nintena. It may cause liver toxicity in rare cases.
- Pregnancy and Breastfeeding: Consult a healthcare provider if pregnant or breastfeeding.
- Regular Monitoring: Long-term use requires monitoring of liver enzymes, kidney function, and blood counts.
- Hypersensitivity: Avoid in patients with a known allergy to Nintena or any of its ingredients.
- Severe Organ Dysfunction: Use with caution in patients with significant liver or kidney impairment.
Nintena may interact with medications that affect liver enzymes, such as CYP3A4 inhibitors or inducers, altering its effectiveness. Always inform your healthcare provider of all medications you are taking.
Storage InstructionsStore Nintena at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Adherence: Take Nintena consistently as prescribed for optimal results.
- Report Symptoms: Contact your healthcare provider if you experience any unusual symptoms.
- Lifestyle Considerations: A healthy lifestyle can enhance the effectiveness of Nintena.
Nintena 150 mg Soft Gelatin is an effective treatment for certain inflammatory and pain conditions. Proper usage, regular monitoring, and communication with healthcare providers are essential for achieving the best therapeutic outcomes.
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Imalek Imatinib 400 mg Tablets
Product Price: Rs 950 / StripGet Best Price
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Product Details:
| Dose/Strength | 400 mg |
| Pack Size | 6 Tablets In 1 Strip |
| Composition | Imatinib 400 mg |
| Brand Name | Imalek 400 |
| manufacturer | Sun Pharmaceutical Industries Ltd |
| Treatment | Cancer |
Imalek Imatinib 400mg Tablets
Overview:
Imalek (Imatinib) is an oral medication used primarily for the treatment of certain types of cancer, particularly chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs), and acute lymphoblastic leukemia (ALL). It belongs to a class of drugs known as tyrosine kinase inhibitors (TKIs). Imatinib works by inhibiting the activity of specific enzymes (tyrosine kinases) involved in the growth and spread of cancer cells. By blocking these enzymes, Imatinib helps to slow or stop the progression of cancer.
Indications:
Imalek 400mg Tablets are primarily indicated for the treatment of:
- Chronic Myelogenous Leukemia (CML): For newly diagnosed adult patients and for patients who are resistant or intolerant to prior therapies.
- Gastrointestinal Stromal Tumors (GISTs): For tumors expressing the c-KIT protein.
- Acute Lymphoblastic Leukemia (ALL): In combination with other chemotherapy agents.
- Other Conditions: Imatinib is also used for other types of cancer such as myelodysplastic/myeloproliferative diseases.
Mechanism of Action:
Imatinib works by targeting and inhibiting the activity of specific proteins, BCR-ABL and c-KIT, that are involved in the growth and division of cancer cells. By blocking these proteins, Imatinib prevents the cancer cells from proliferating, thereby slowing tumor growth and reducing the likelihood of cancer spread.
Dosage and Administration:
- Recommended Dose: The typical dose for CML is 400 mg once daily. The dose may be increased depending on the patient's response and tolerance to the drug.
- Administration: Imatek should be taken with food and a large glass of water to minimize stomach upset. The tablets should be swallowed whole and not crushed or chewed.
- Missed Dose: If a dose is missed, it should be taken as soon as possible, but skip if it is close to the next dose.
Side Effects:
Common side effects include:
- Nausea and vomiting
- Diarrhea
- Fatigue
- Edema (swelling)
- Muscle cramps Serious side effects may include:
- Liver dysfunction
- Heart problems (such as arrhythmias)
- Bleeding
Precautions:
- Liver Function: Regular monitoring of liver enzymes is essential.
- Heart Health: Patients with heart problems should be closely monitored.
- Pregnancy: Imatinib should not be used during pregnancy unless necessary.
Storage:
Store at room temperature (20°C to 25°C). Keep in the original packaging, away from moisture and light.
Conclusion:
Imalek 400mg Tablets are an effective treatment option for CML, GISTs, and other cancers. Monitoring for potential side effects such as liver toxicity and heart problems is important for ensuring safety during treatment.
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Nintena 100 mg Soft Gelatin Capsules
Product Price: Rs 590 / BoxGet Best Price
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Product Details:
| Strength | 100 mg |
| Prescription/Non prescription | Prescription |
| Product Form | Capsules |
| Brand | Nintena |
| Pack Size | 1x10 Cap |
Nintena 100mg Soft Gelatin Capsules
Overview:
Nintena (also known as Nintedanib) is an oral medication used primarily in the treatment of idiopathic pulmonary fibrosis (IPF), non-small cell lung cancer (NSCLC), and systemic sclerosis-associated interstitial lung disease (SSc-ILD). Nintena is a tyrosine kinase inhibitor that works by blocking the activity of several enzymes involved in the growth and spread of cancer cells and fibrosis.
Indications:
Nintena 100mg Soft Gelatin Capsules are indicated for:
- Idiopathic Pulmonary Fibrosis (IPF): To slow disease progression and reduce lung function decline.
- Non-Small Cell Lung Cancer (NSCLC): In combination with other therapies for advanced or metastatic NSCLC.
- Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD): To manage lung involvement in systemic sclerosis.
Mechanism of Action:
Nintedanib is an inhibitor of multiple receptor tyrosine kinases, including VEGFR, FGFR, and PDGFR. By blocking these receptors, it reduces the formation of abnormal blood vessels and prevents fibrosis progression. This inhibition slows the decline in lung function in IPF and helps reduce the growth of tumors in NSCLC.
Dosage and Administration:
- Recommended Dose: Typically, the dose is 100mg twice daily (morning and evening) for IPF and SSc-ILD patients. The dosage for NSCLC may vary based on the combination regimen.
- Administration: Take capsules with food to minimize gastrointestinal side effects. Do not crush or chew the capsules.
- Missed Dose: If a dose is missed, take it as soon as possible unless it's almost time for the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Diarrhea, nausea, vomiting, and fatigue.
Serious side effects may include: - Liver dysfunction, high blood pressure, and bleeding complications.
Precautions:
- Liver Function: Monitor liver enzymes before and during treatment.
- Cardiovascular Conditions: Monitor for hypertension and manage accordingly.
- Pregnancy: Nintena should be avoided during pregnancy due to potential harm to the fetus.
Storage:
Store Nintena capsules at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Nintena 100mg Soft Gelatin Capsules are effective in treating IPF, NSCLC, and SSc-ILD. Regular monitoring for side effects, including liver function and blood pressure, is essential for safety.
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400mg Mesylonib Imatinib Mesylate Tablets
Product Price: Rs 2,500 / BoxGet Best Price
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Product Details:
| Dose/Strength | 400 mg |
| Form | Tablet |
| Packaging Size | 10 Tablets |
| Packaging Type | Box |
| Shelf Life | 24 Months |
| Brand Name | Mesylonib |
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Valganciclovir 450mg tablet (Virolfi)
Product Price: Rs 2,100 / StripeGet Best Price
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Product Details:
| Packaging Size | 1*10 Tablets |
| Packaging Type | Stripe |
| Brand | Virolfi 450mg |
| Treatment | Cytomegalovirus Infection |
| Manufacturer | Zydus Lifesciences Ltd |
| Prescription/Non prescription | Non prescription |
Valganciclovir, sold under the brand name Virolfi, is an antiviral medication primarily used to prevent and treat cytomegalovirus (CMV) infections in individuals at risk, particularly those who have undergone organ transplantation or are immunocompromised.
IndicationsValganciclovir is indicated for:
- Prevention of CMV Infection: Used in high-risk patients post-organ transplant, especially kidney and heart recipients.
- Treatment of CMV Retinitis: Primarily in patients with acquired immunodeficiency syndrome (AIDS).
Valganciclovir is a prodrug that is converted to ganciclovir in the body. Ganciclovir interferes with viral DNA synthesis by inhibiting viral DNA polymerase. This action effectively reduces viral replication, helping to control CMV infections.
Dosage and Administration- Standard Dosage: For prevention in transplant recipients, the typical dose is 900 mg once daily for 100 days post-transplant. For treatment of CMV retinitis, the dose may be higher and adjusted based on patient response and tolerability.
- Administration: Valganciclovir should be taken orally with food to enhance absorption. Tablets should not be crushed or chewed.
Valganciclovir is contraindicated in:
- Hypersensitivity: Known allergy to valganciclovir, ganciclovir, or any components of the formulation.
- Pregnancy and Lactation: Should be avoided due to potential harm to the fetus or nursing infant.
- Myelosuppression: Monitor blood counts regularly, as valganciclovir can cause bone marrow suppression, leading to neutropenia, anemia, and thrombocytopenia.
- Fertility Effects: May affect fertility in both men and women; effective contraceptive measures are recommended during treatment.
- Renal Impairment: Dosage adjustments are necessary for patients with renal impairment.
Common side effects may include:
- Diarrhea
- Nausea and vomiting
- Fatigue
- Headache
- Fever
Serious side effects can include:
- Severe allergic reactions (anaphylaxis)
- Myelosuppression (severe neutropenia or thrombocytopenia)
- Seizures (in rare cases)
- Renal toxicity
Valganciclovir may interact with other medications, particularly those that affect renal function or also cause myelosuppression. Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements.
Storage InstructionsStore Valganciclovir 450 mg Tablets (Virolfi) at room temperature, away from moisture and heat. Keep out of reach of children.
Patient Counseling Information- Advise patients to report any signs of infection, unusual bleeding, or severe side effects.
- Discuss the importance of adherence to the prescribed regimen and the need for regular blood tests to monitor health.
- Inform patients about the potential impact on fertility and the importance of effective contraception during treatment.
Valganciclovir 450 mg Tablets (Virolfi) are essential for preventing and treating CMV infections in at-risk populations. Close monitoring and communication with healthcare providers are critical for managing side effects and ensuring effective treatment.
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Reditux Rituximab 500 Mg Injection
Product Price: Rs 28,500 / VialGet Best Price
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Product Details:
| Strength | 500 mg |
| Packaging Size | 50 ml |
| Packaging Type | Vial |
| Brand | Reditux 500mg |
| Manufacturer | Dr Reddy's Laboratories Ltd |
| Usage / Application | Hospital |
| Storage Conditions | 2 - 8 DegreeC |
Indications: Rituximab is primarily indicated for:
- Treatment of B-cell non-Hodgkin lymphoma (NHL).
- Treatment of chronic lymphocytic leukemia (CLL) in combination with chemotherapy.
- Treatment of rheumatoid arthritis in combination with methotrexate for patients who have not responded adequately to other therapies.
- Treatment of granulomatosis with polyangiitis (Wegener's granulomatosis) and microscopic polyangiitis.
Mechanism of Action: Rituximab is a monoclonal antibody that targets the CD20 antigen on the surface of B-cells. By binding to CD20, it induces B-cell lysis through various mechanisms, including complement-dependent cytotoxicity and antibody-dependent cellular cytotoxicity, leading to a reduction in malignant and autoimmune B-cells.
Dosage and Administration:
- Typical Dosage: The dosage may vary based on the indication:
- For NHL: 375 mg/m² body surface area (BSA) administered intravenously once a week for a specific number of weeks.
- For rheumatoid arthritis: 1000 mg administered intravenously on two occasions, separated by two weeks.
- Administration: Infusion should be performed by a qualified healthcare professional in a facility equipped for the management of infusion reactions. Monitor patients closely during the infusion for any adverse reactions.
Side Effects:
- Common: Infusion-related reactions (fever, chills, nausea), headache, fatigue, and skin rash.
- Serious: Severe infections (including reactivation of hepatitis B), tumor lysis syndrome, and cardiac events.
Contraindications:
- Hypersensitivity to rituximab or any component of the formulation.
- Active infections or significant immune suppression.
Warnings and Precautions:
- Infections: Monitor for signs of infections and ensure appropriate screening for hepatitis B before treatment.
- Cardiovascular Events: Patients with a history of cardiovascular disease should be monitored closely during treatment.
- Tumor Lysis Syndrome: Particularly in patients with high tumor burden; hydration and monitoring are essential.
Drug Interactions: Rituximab may interact with other immunosuppressive therapies. Always inform healthcare providers of all medications being taken.
Storage: Store in a refrigerator (2°C to 8°C / 36°F to 46°F) and protect from light. Do not freeze.
Patient Counseling Information:
- Inform patients about the potential for infusion reactions and the importance of reporting any symptoms during and after the infusion.
- Advise patients to report any signs of infection, such as fever or persistent cough, after treatment.
- Discuss the importance of regular follow-up appointments for monitoring and management of side effects.
Reditux (Rituximab 500 mg Injection) is an important therapeutic option for various hematological malignancies and autoimmune disorders. Patients should be well-informed about its use, potential side effects, and the importance of monitoring during treatment. Always consult a healthcare provider for personalized medical advice.
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Bdparp Olaparib 150mg Tablet
Product Price: Rs 7,500 / BoxGet Best Price
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Product Details:
| Dose/Strength | 150 mg |
| Form | Tablet |
| Brand | Bdparp |
| Packaging Size | 56 Tablets per Box |
| Manufacturer | BDR Pharmaceuticals Internationals Pvt Ltd |
Bdparp is a brand of Olaparib, an oral medication classified as a PARP (poly (ADP-ribose) polymerase) inhibitor. It is used primarily in the treatment of certain types of cancers that are associated with inherited mutations in BRCA1 and BRCA2 genes.
IndicationsBdparp is indicated for:
- Ovarian Cancer: Treatment of patients with recurrent ovarian cancer who have been previously treated with chemotherapy and have BRCA mutations.
- Breast Cancer: Used in patients with HER2-negative breast cancer and BRCA mutations, particularly after prior chemotherapy.
- Pancreatic and Prostate Cancer: Approved for use in specific cases of metastatic pancreatic and prostate cancer with BRCA mutations.
Olaparib works by inhibiting the PARP enzyme, which plays a crucial role in repairing single-strand breaks in DNA. In cancer cells with defective BRCA genes, the inhibition of PARP leads to the accumulation of DNA damage, resulting in cell death. This mechanism exploits the concept of "synthetic lethality."
Dosage and Administration- Standard Dosage: The recommended dose of Bdparp is 300 mg (two 150 mg tablets) taken orally twice daily. Adjustments may be needed based on individual tolerance and specific clinical situations.
- Administration: Can be taken with or without food. It is essential to swallow the tablets whole without chewing or crushing.
Bdparp is contraindicated in:
- Hypersensitivity: Known allergy to olaparib or any component of the formulation.
- Severe Liver Impairment: Patients with significant liver dysfunction should not use this medication.
- Bone Marrow Suppression: Monitor blood counts regularly due to the risk of myelosuppression, including anemia, neutropenia, and thrombocytopenia.
- Secondary Malignancies: There is a risk of developing secondary cancers; patients should be monitored accordingly.
- Pregnancy and Lactation: Not recommended during pregnancy or breastfeeding due to potential harm to the fetus or infant.
Common side effects may include:
- Nausea and vomiting
- Fatigue
- Anemia
- Diarrhea
- Headache
Serious side effects can include:
- Myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML)
- Severe allergic reactions (anaphylaxis)
- Pulmonary toxicity
Olaparib may interact with medications that affect liver enzymes, particularly CYP3A. Patients should inform their healthcare provider about all medications, including over-the-counter drugs and supplements.
Storage InstructionsStore Bdparp (Olaparib 150 mg Tablet) at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to report any signs of bleeding, unusual bruising, or signs of infection.
- Emphasize the importance of adhering to the prescribed dosing schedule and attending regular follow-up appointments.
- Inform patients about potential side effects and the need for monitoring.
Bdparp (Olaparib 150 mg Tablet) is a targeted therapy for specific cancers associated with BRCA mutations, offering a critical treatment option. Proper administration and monitoring are essential to maximize treatment effectiveness and minimize risks.
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Bracaloc Olaparib 150mg Tablet
Product Price: Rs 5,500 / BoxGet Best Price
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Product Details:
| Dose/Strength | 150 mg |
| Brand | Bracaloc |
| Packaging Size | 30 Tablets in 1 Box |
| Manufacturer | Samarth Life Sciences Pvt Ltd |
| Treatment | Breast cancer, Ovarian cancer |
Bracaloc is a formulation of Olaparib, an oral medication classified as a PARP (poly (ADP-ribose) polymerase) inhibitor. It is primarily used in the treatment of cancers associated with inherited mutations in BRCA1 and BRCA2 genes.
IndicationsBracaloc is indicated for:
- Ovarian Cancer: Treatment of patients with recurrent ovarian cancer who have responded to chemotherapy and carry BRCA mutations.
- Breast Cancer: Used in patients with HER2-negative breast cancer and BRCA mutations, particularly following chemotherapy.
- Pancreatic and Prostate Cancer: Approved for metastatic pancreatic and prostate cancer in specific cases related to BRCA mutations.
Olaparib inhibits the PARP enzyme, which is crucial for repairing single-strand breaks in DNA. This action is particularly effective in cancer cells with BRCA mutations, leading to the accumulation of DNA damage and subsequent cell death. This concept is known as "synthetic lethality."
Dosage and Administration- Standard Dosage: The recommended dose is 300 mg (two 150 mg tablets) taken orally twice daily. Adjustments may be necessary based on individual tolerance and clinical response.
- Administration: Can be taken with or without food. Swallow the tablets whole; do not chew or crush.
Bracaloc is contraindicated in:
- Hypersensitivity: Known allergy to olaparib or any component of the formulation.
- Severe Liver Impairment: Use in patients with significant liver dysfunction is not recommended.
- Bone Marrow Suppression: Regular monitoring of blood counts is essential due to the risk of myelosuppression, including anemia and neutropenia.
- Secondary Malignancies: There is a potential risk of developing secondary cancers; patients should be monitored accordingly.
- Pregnancy and Lactation: Not recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant.
Common side effects may include:
- Nausea and vomiting
- Fatigue
- Anemia
- Diarrhea
- Headache
Serious side effects can include:
- Myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML)
- Severe allergic reactions (anaphylaxis)
- Pulmonary toxicity
Olaparib may interact with other medications that affect liver enzymes, especially those in the CYP3A family. Patients should inform their healthcare provider about all medications they are taking, including over-the-counter drugs and supplements.
Storage InstructionsStore Bracaloc (Olaparib 150 mg Tablet) at room temperature, away from moisture and light. Keep out of reach of children.
Patient Counseling Information- Advise patients to report any unusual bleeding, bruising, or signs of infection.
- Emphasize the importance of adhering to the prescribed dosing schedule and attending regular follow-up appointments.
- Inform patients about potential side effects and the need for regular monitoring.
Bracaloc (Olaparib 150 mg Tablet) offers a targeted therapy for specific cancers linked to BRCA mutations, providing an important treatment option. Proper administration and monitoring are vital for maximizing therapeutic benefits and minimizing risks.
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Doxorubicin Hydrochloride Injection IP 50 Mg ( Duxocin 50 )
Product Price: Rs 175 / VialGet Best Price
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Product Details:
| Strength | 50 mg |
| Form | Injection |
| Pack Type | Vial |
| Brand Name | Duxocin 50 |
| Manufacturer | Zydus |
| Country of Origin | Made in India |
| Composition | Doxorubicin Hydrochloride IP 50 mg |
Indications: Duxocin (doxorubicin hydrochloride) is primarily indicated for:
- Treatment of various cancers, including breast cancer, bladder cancer, ovarian cancer, lung cancer, and certain types of leukemia and lymphoma.
Mechanism of Action: Doxorubicin is an anthracycline antibiotic that works by intercalating into DNA, inhibiting DNA and RNA synthesis. This leads to the disruption of cell replication and the induction of apoptosis (programmed cell death) in rapidly dividing cancer cells.
Dosage and Administration:
- Typical Dosage: The dosage depends on the type of cancer being treated, the treatment protocol, and the patient's overall health. Common regimens may range from 60 mg/m² to 75 mg/m² administered intravenously, typically every 21 to 28 days.
- Administration: Doxorubicin should be administered under the supervision of a healthcare professional. It is usually given as an intravenous infusion, with careful monitoring for any adverse reactions.
Side Effects:
- Common: Nausea, vomiting, hair loss, fatigue, and mouth sores.
- Serious: Cardiotoxicity (heart damage), severe allergic reactions, and secondary malignancies.
Contraindications:
- Hypersensitivity to doxorubicin or any component of the formulation.
- Patients with pre-existing heart conditions or significant liver impairment.
Warnings and Precautions:
- Cardiotoxicity: Regular cardiac monitoring is recommended, particularly in patients with a history of heart disease or those receiving high cumulative doses.
- Extravasation Risk: Care must be taken to avoid extravasation (leakage into surrounding tissue), which can cause severe tissue damage.
- Myelosuppression: Monitor blood counts regularly, as doxorubicin can lead to decreased blood cell production.
Drug Interactions: Doxorubicin may interact with other medications that affect the heart or blood cell production. Inform healthcare providers of all medications being taken, including over-the-counter drugs and supplements.
Storage: Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from light. Avoid freezing.
Patient Counseling Information:
- Advise patients about the potential side effects and the importance of reporting any unusual symptoms, especially cardiovascular issues.
- Discuss the need for regular monitoring during treatment and adherence to follow-up appointments.
- Encourage patients to maintain hydration and discuss any dietary adjustments that may help manage side effects.
Duxocin (Doxorubicin Hydrochloride Injection IP 50 mg) is an effective chemotherapeutic agent for various types of cancer. Patients should be well-informed about its use, potential side effects, and the importance of adherence to their treatment regimen. Always consult a healthcare provider for personalized medical advice.
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Wepox Erythropoietin 10000iu Injection
Product Price: Rs 1,000 / PieceGet Best Price
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Product Details:
| Strength | 10000 IU |
| Packaging Type | 1 ml in 1 Prefilled Syringe |
| Salt Composition | Recombinant Human Erythropoietin Alfa 10000IU |
| Brand Name | Wepox |
| Manufacturer | Wockhardt Ltd |
| Usage/Application | Anemia Due To Cancer Chemotherapy |
Wepox Erythropoietin 10000 IU Injection
Overview:Wepox is an injectable medication containing Erythropoietin, a synthetic form of a hormone naturally produced by the kidneys. Erythropoietin stimulates the bone marrow to produce red blood cells. It is primarily used to treat anemia (low red blood cell count) associated with chronic kidney disease, chemotherapy, or certain other conditions. Wepox helps increase red blood cell production, thereby improving oxygen delivery to tissues and alleviating symptoms of anemia.
Indications: Wepox 10000 IU Injection is indicated for:
- Chronic Kidney Disease (CKD): To treat anemia in patients with chronic renal failure, whether undergoing dialysis or not.
- Chemotherapy-induced Anemia: To manage anemia in cancer patients undergoing chemotherapy.
- HIV/AIDS-related Anemia: For patients with anemia caused by HIV infection or antiretroviral therapy.
- Other Anemia Conditions: Such as anemia from bone marrow disorders or chronic inflammatory diseases.
Mechanism of Action: Erythropoietin binds to specific receptors in the bone marrow, stimulating the production of red blood cells from precursor cells. This process is crucial in replenishing red blood cell levels, particularly in conditions where production is impaired, such as in CKD or chemotherapy-induced suppression.
Dosage and Administration:
- Recommended Dose: The usual starting dose for adults with anemia of chronic kidney disease is 50–100 IU/kg body weight, administered subcutaneously or intravenously once a week.
- Administration: Wepox is given as an injection, typically administered by a healthcare provider. The exact dosage and schedule depend on the patient's hemoglobin levels and medical condition.
Side Effects: Common side effects include:
- Injection site reactions: Redness, swelling, or pain at the injection site.
- Headache, fatigue, and nausea. Serious side effects may include:
- Hypertension: High blood pressure, especially in patients with CKD.
- Blood clots: Increased risk of thrombosis (blood clots), which could lead to heart attack or stroke.
- Severe allergic reactions: Rare but may include rash, swelling, or difficulty breathing.
Precautions:
- Cardiovascular Conditions: Monitor blood pressure and cardiovascular health closely, as Erythropoietin can increase the risk of stroke or heart attack in some patients.
- Iron Deficiency: Adequate iron levels are required for the effectiveness of Erythropoietin, so iron supplementation may be necessary.
- Pregnancy and Breastfeeding: Use only if clearly needed and under a healthcare provider's supervision.
Storage: Store Wepox 10000 IU Injection in the refrigerator (2°C to 8°C), protected from light. Do not freeze. Keep out of reach of children.
Conclusion: Wepox (Erythropoietin 10000 IU) is an essential treatment for anemia in conditions like chronic kidney disease and chemotherapy-induced anemia. Careful monitoring of blood pressure, iron levels, and red blood cell counts is necessary to ensure safe and effective use.
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Atranza Tretinoin 10mg Capsules
Product Price: Rs 7,000 / BottleGet Best Price
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Product Details:
| Strength | 10 mg |
| Packaging Size | 100 Capsules |
| Composition | Tretinoin 10 mg |
| Brand Name | Atranza Capsule |
| Manufacturer | Intas Pharmaceuticals Ltd |
| Treatment | Acute Promyelocytic Leukaemia |
Atranza (Tretinoin) 10 mg Capsules
OverviewAtranza contains tretinoin, a derivative of vitamin A, used primarily in the treatment of acute promyelocytic leukemia (APL) and certain skin conditions. It is known for its role in promoting cell differentiation and reducing the proliferation of malignant cells.
Indications- Acute Promyelocytic Leukemia (APL): Used as part of a combination therapy for patients with APL, typically in the presence of the promyelocytic leukemia-retinoic acid receptor (PML-RAR) fusion gene.
- Skin Conditions: In some formulations, tretinoin is used topically for conditions like acne and photoaging, but this may not apply to oral capsules.
Tretinoin binds to specific retinoic acid receptors, regulating gene expression involved in cell growth, differentiation, and apoptosis. In APL, it promotes the differentiation of immature promyelocytes into mature granulocytes, helping to restore normal blood cell production.
Dosage and Administration- Typical Dosage: For APL, the usual starting dose is 45 mg/m²/day, taken in divided doses, but dosing may vary based on clinical response and treatment protocol.
- Administration: Capsules should be taken orally, preferably with food to enhance absorption. Swallow the capsules whole; do not chew or crush.
- Common Side Effects:
- Headache
- Fatigue
- Nausea and vomiting
- Skin dryness and peeling
- Serious Side Effects:
- Differentiation syndrome (fever, weight gain, respiratory distress, edema)
- Severe allergic reactions
- Liver dysfunction
- Hypersensitivity to tretinoin or any component of the formulation.
- Pregnancy is contraindicated due to potential teratogenic effects.
- Monitor for signs of differentiation syndrome, especially during the first few weeks of treatment.
- Regular liver function tests may be required due to the risk of hepatotoxicity.
- Store at room temperature (20°C to 25°C / 68°F to 77°F) and protect from moisture and light.
- Educate patients about potential side effects and the importance of reporting severe symptoms, particularly signs of differentiation syndrome.
- Discuss the importance of using effective contraception during treatment and avoiding pregnancy.
Atranza (tretinoin) is an important treatment option for acute promyelocytic leukemia, promoting differentiation of cancer cells and improving outcomes. Proper dosing, monitoring for side effects, and patient education are crucial for effective treatment. Always consult a healthcare provider for personalized medical advice.
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25mg Igurati Tablets
Product Price: Rs 250 / BoxGet Best Price
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Product Details:
| Packing Type | Box |
| Brand | Ipca |
| Shelf Life | 24 Months |
| Usage | Pain and Inflammation |
| Pack Size | 10 Tablets |
Igurati 25mg Tablet is used to treat rheumatoid arthritis. It works by improving abnormal immunological responses and suppressing the production of substances that cause redness and swelling.
Igurati 25mg Tablet can be taken with or without food. Take it regularly and do not stop taking the medicine even if you get better until that doctor tells you it is alright to stop. Drink an adequate amount of water while on treatment with this medicine, this will prevent you from getting kidney stones.
The most common side effects of this medicine include liver dysfunction, pneumonia, and upper abdominal pain. If any of these side effects persist or worsen, let yor doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you an alternative medicine or by adjusting the dose.
To make sure the medicine is safe for you, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also let your doctor know all the other medicines you are taking before using this medicine. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.
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Nirmix Aminoacid Injection
Product Price: Rs 1,500 / VialGet Best Price
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Product Details:
| Packaging Size | 100 ml |
| Strength | 10% w/v |
| Brand Name | Aculife |
| Shelf Life | 24 Months |
| Pack Type | Box |
| Box Contains | 1 Vial |
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Azacite Azacitidine Injections
Product Price: Rs 5,600 / VialGet Best Price
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Product Details:
| Strength | 100 mg |
| Packaging Type | Box |
| Brand | Getwell |
| Pack Size | 1 Vial |
| Shelf Life | 24 Months |
| Usage | Used To Treat Blood Cancer |
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50mg Albu Bicalutamide Tablets
Product Price: Rs 400 / BoxGet Best Price
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Product Details:
| Strength | 50 mg |
| Form | Tablet |
| Packaging Type | Box |
| Packaging Size | 3x10 Tablets |
| Brand | Neon |
| Shelf Life | 24 Months |
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Bicalutamide Tablets (Caludec 50 mg Tablet)
Product Price: Rs 400 / StripGet Best Price
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Product Details:
| Strength | 50 mg |
| Pack Size | 10 Tablets In 1 Strip |
| Composition | Bicalutamide 50 mg |
| Brand Name | Caludec 50 mg |
| manufactured By | Samarth Life Sciences Pvt Ltd |
| Treatment | Prostate cancer |
Bicalutamide Tablets (Caludec 50 mg Tablets)
Overview:Caludec 50 mg Tablets contain Bicalutamide, a non-steroidal anti-androgen used in the treatment of prostate cancer. Bicalutamide works by blocking the action of testosterone, the male hormone, on cancer cells. It binds to androgen receptors on the surface of prostate cancer cells, preventing testosterone from stimulating their growth. As prostate cancer cells rely on testosterone for growth, Bicalutamide helps reduce tumor size and progression, making it an essential component of hormonal therapy in prostate cancer management.
Indications:Caludec 50 mg Tablets are primarily indicated for:
- Prostate Cancer: Used in combination with LHRH agonists (luteinizing hormone-releasing hormone agonists) as first-line treatment for advanced or metastatic prostate cancer. Bicalutamide blocks the androgen receptors, effectively reducing testosterone’s ability to fuel cancer cell growth.
- Adjuvant Therapy: In some cases, Bicalutamide is used as adjuvant therapy for locally advanced prostate cancer after surgery or radiation therapy to reduce the risk of recurrence.
Bicalutamide is a pure androgen receptor antagonist. It works by binding to androgen receptors on prostate cancer cells, effectively blocking testosterone and other androgens from interacting with these receptors. By inhibiting this pathway, Bicalutamide decreases tumor growth and can slow down the progression of prostate cancer. This makes it a vital component of treatment, especially for hormone-sensitive prostate cancer.
Dosage and Administration:- Recommended Dose: The usual dose is one 50 mg tablet once daily, taken with or without food.
- Administration: Swallow the tablet whole with water. It is best to take it at the same time each day to maintain consistent drug levels in the body.
- Common Side Effects: Hot flashes, fatigue, nausea, breast tenderness or enlargement, and liver enzyme abnormalities.
- Serious Side Effects: Liver toxicity, cardiovascular problems (e.g., heart attack, stroke), and gynecomastia (enlargement of breast tissue in men). Patients may need regular liver function tests and monitoring for cardiovascular events.
- Liver Function: Regular monitoring of liver function is recommended, as Bicalutamide can cause liver toxicity in some patients. Treatment should be stopped if liver damage is detected.
- Cardiovascular Risk: Patients with a history of cardiovascular disease should be monitored for potential heart-related side effects, as Bicalutamide may increase the risk of heart attack or stroke.
- Pregnancy and Lactation: Bicalutamide is contraindicated in women and should not be used during pregnancy or breastfeeding due to potential harm to the fetus or infant.
Store Caludec 50 mg Tablets at room temperature (15°C to 30°C), away from light and moisture. Keep out of reach of children.
Conclusion:Caludec 50 mg Tablets (Bicalutamide) are a crucial part of hormone therapy for prostate cancer, especially for advanced or metastatic stages of the disease. By blocking the effects of testosterone on prostate cancer cells, it helps slow tumor growth and improves patient outcomes. Regular monitoring for liver function and cardiovascular health is necessary during treatment to minimize potential risks and ensure the therapy's effectiveness.
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250mg Abnib Lapatinib Tablets
Product Price: Rs 6,500 / BoxGet Best Price
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Product Details:
| Packaging Size | 30 Tablets |
| Form | Tablet |
| Strength | 250 mg |
| Brand | Abbott |
| Pack Type | Boz |
Abnib 250mg Tablet is utilized in the therapy of breast cancer. It works by halting or dialing back the development of cancer cells. It is either utilized alone or in blend with another medication to fix progressed stage breast cancer.
Abnib 250mg Tablet ought to be taken while starving or an hour prior or 2 hours after a dinner. The portion and span fluctuate as per the seriousness of your condition and your reaction to treatment. Take it precisely as endorsed to keep away from serious side effects. It might require a little while or months for you to see or feel the advantages yet don't quit taking it except if your doctor tells you to.
USES OF ABNIB TABLET:
- Breast cancer
Benefits OF ABNIB TABLET:
In Breast cancer
Abnib 250mg Tablet assists with treating breast cancer and it very well might be utilized alone or in mix with different prescriptions or therapy modalities like chemotherapy. It frees the side effects from breast cancer, for example, breast bumps, horrendous release from areolas or changes in the shape or surface of the breast. Abnib 250mg Tablet kills or stops the development of cancer cells and furthermore forestalls the increase of cancer cells. Talk about with your doctor assuming any of the side effects irritate you.
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Regonat 40 mg Regorafenib Tablets
Product Price: Rs 10,000 / BottleGet Best Price
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Product Details:
| Packaging Size | 28 Tablets |
| Strength | 40 mg |
| Pack Size | 28 Tablets in 1 Strip |
| Composition | Regorafenib 40 mg |
| Brand | Regonat 40 mg |
| Manufacturer | Natco Pharma Ltd |
| Treatment | Cancer of Colon and Rectum |
Regonat 40 mg Regorafenib Tablets
Overview:Regonat 40 mg Tablets contain Regorafenib, a multi-kinase inhibitor used in the treatment of various cancers, including metastatic colorectal cancer, gastrointestinal stromal tumors (GIST), and hepatocellular carcinoma (HCC). It targets multiple kinases involved in tumor growth, angiogenesis (formation of blood vessels), and cancer cell survival. By blocking these pathways, Regonat slows the progression of cancer, particularly in patients who have not responded to previous treatments.
Indications:Regonat 40 mg Tablets are indicated for:
- Metastatic Colorectal Cancer (mCRC): For patients who have previously received chemotherapy and anti-VEGF therapy.
- Gastrointestinal Stromal Tumors (GIST): For patients who have failed previous treatments with imatinib or sunitinib.
- Hepatocellular Carcinoma (HCC): For patients who have been treated with sorafenib or are not candidates for surgical intervention.
Regorafenib works by inhibiting multiple kinases involved in cancer cell proliferation, angiogenesis, and metastasis. These kinases are essential for the growth and spread of cancer cells. By targeting them, Regonat disrupts the tumor's blood supply and growth, leading to tumor shrinkage and slowed disease progression. This multi-target approach makes Regonat effective in various solid tumors.
Dosage and Administration:- Recommended Dose: 160 mg once daily, taken orally, for the first 3 weeks of a 28-day cycle.
- Administration: Take the tablet with or without food, swallow it whole with a glass of water. Do not chew or crush.
- Common: Fatigue, diarrhea, nausea, decreased appetite, and skin rashes.
- Serious: Hepatotoxicity, bleeding, hypertension, and hand-foot syndrome. Regular liver and blood pressure monitoring is necessary.
- Liver Function: Monitor for hepatic impairment as Regonat may cause liver toxicity.
- Bleeding Risk: Use cautiously in patients with bleeding disorders.
- Hypertension: Monitor blood pressure regularly.
- Pregnancy: Contraindicated during pregnancy and breastfeeding.
Store at room temperature (15°C-30°C), away from light and moisture.
Conclusion:Regonat (Regorafenib 40 mg Tablets) is an effective treatment for metastatic colorectal cancer, GIST, and HCC. It inhibits multiple kinases critical for cancer cell survival, reducing tumor growth and spread. Regular monitoring is essential for safety.
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250mg Etibo Lapatinib Tablet
Product Price: Rs 7,000 / BoxGet Best Price
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Product Details:
| Packaging Size | 30 Tablets |
| Form | Tablet |
| Strength | 250 mg |
| Brand | Samarth |
| Pack Type | Box |
Etibo 250mg Tablet is utilized in the therapy of breast cancer. It works by halting or dialing back the development of cancer cells. It is either utilized alone or in blend with another medication to fix progressed stage breast cancer.
Etibo 250mg Tablet ought to be taken while starving or an hour prior or 2 hours after a dinner. The portion and span shift as indicated by the seriousness of your condition and your reaction to treatment. Take it precisely as recommended to stay away from serious side effects. It might require a little while or months for you to see or feel the advantages however don't quit taking it except if your doctor tells you to.
Uses of Etibo 250mg Tablet:
- Breast cancer
Benefits of Etibo 250mg Tablet:
In Breast cancer
Etibo 250mg Tablet assists with treating breast cancer and it could be utilized alone or in mix with different meds or therapy modalities like chemotherapy. It frees the side effects from breast cancer, for example, breast protuberances, ridiculous release from areolas or changes in the shape or surface of the breast. Etibo 250mg Tablet kills or stops the development of cancer cells and furthermore forestalls the duplication of cancer cells. Examine with your doctor assuming that any of the side effects irritate you.
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Abatitor Abiraterone Acetate 250mg Tablets
Product Price: Rs 38,000 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Form | Tablet |
| Prescription/Non prescription | Prescription |
| Brand | Abatitor |
| Composition | Abiraterone Acetate |
Abatitor 250mg Tablets (Abiraterone Acetate)
Overview:
Abatitor (Abiraterone Acetate) is an oral medication used primarily in the treatment of metastatic castration-resistant prostate cancer (mCRPC). It works by inhibiting the enzyme CYP17A1, which is involved in the production of androgens (male hormones) in the body, including testosterone. By reducing androgen levels, Abatitor helps to slow or stop the growth of prostate cancer cells, which rely on androgens for growth.
Indications:
Abatitor 250mg Tablets are indicated for:
- Metastatic Castration-Resistant Prostate Cancer (mCRPC): Used in combination with prednisone to treat mCRPC in men who have received prior treatment with chemotherapy or hormone therapy.
Mechanism of Action:
Abiraterone acetate is a CYP17A1 inhibitor that blocks the production of testosterone and other androgens. This leads to a significant decrease in androgen levels, which are necessary for the growth of prostate cancer cells. By inhibiting androgen production, Abatitor helps to suppress cancer cell proliferation and slows disease progression in prostate cancer.
Dosage and Administration:
- Recommended Dose: The usual dose is 1000 mg (4 tablets of 250 mg) once daily, taken on an empty stomach at least 1 hour before or 2 hours after food.
- Administration: Abatitor is taken orally, swallowed whole with water. It should not be crushed or chewed.
- Missed Dose: If a dose is missed, it should be taken as soon as possible, unless it is close to the next scheduled dose.
Side Effects:
Common side effects include:
- Fatigue, hot flashes, joint pain, and diarrhea.
Serious side effects may include: - Liver toxicity: Elevated liver enzymes, requiring monitoring of liver function.
- Adrenal insufficiency: Potential hormonal imbalances due to decreased cortisol levels.
- Hypertension: Increased blood pressure, particularly when used with corticosteroids.
Precautions:
- Liver Disease: Abatitor should be used with caution in patients with liver impairment.
- Pregnancy and Breastfeeding: Abatitor is contraindicated in pregnancy and should not be used by breastfeeding women due to potential harm to the fetus or infant.
- Corticosteroids: Prednisone should be used alongside Abatitor to manage potential side effects like adrenal insufficiency.
Storage:
Store Abatitor 250mg Tablets at room temperature (20°C to 25°C), away from light and moisture. Keep the tablets out of reach of children.
Conclusion:
Abatitor 250mg Tablets is a potent medication used to treat metastatic castration-resistant prostate cancer. Regular monitoring for liver function, blood pressure, and potential side effects is important to ensure safe and effective treatment.
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Pomalid Pomalidomide 1 mg Capsules
Product Price: Rs 2,500 / BottleGet Best Price
Product Brochure
Product Details:
| Packaging Size | 21 Capsules in 1 Bottle |
| Brand Name | Pomalid |
| Manufactured By | Natco Pharma Ltd |
| Treatment | To treat AIDS related Kaposi Sarcoma |
| Strength | 4 mg |
Pomalidomide 1 mg Capsules (Pomalid 1 mg Capsules)
Indications:
Pomalidomide is indicated for the treatment of multiple myeloma in patients who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor, and have shown disease progression.
Mechanism of Action:
Pomalidomide is an immunomodulatory drug (IMiD) that works by enhancing immune response against cancer cells, inhibiting their proliferation, and disrupting the tumor microenvironment. It has anti-angiogenic properties, which contribute to its anti-cancer effects.
Dosage and Administration:
- Dosage: The recommended starting dose of Pomalidomide is 1 mg taken orally once daily.
- Administration: Capsules should be taken at the same time each day, with or without food. Swallow capsules whole; do not open or chew.
Contraindications:
- Hypersensitivity to pomalidomide or any component of the formulation.
- Pregnancy: Pomalidomide is contraindicated in pregnant women due to risks of fetal harm.
Warnings and Precautions:
- Blood Disorders: Monitor patients for neutropenia, thrombocytopenia, and anemia. Regular blood counts are advised.
- Thromboembolic Risks: There is an increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE). Consider thromboprophylaxis for at-risk patients.
- Pregnancy Prevention: Effective contraception is essential for both men and women during treatment and for a specified period after treatment ends.
Side Effects:
Common side effects may include:
- Fatigue
- Neutropenia
- Anemia
- Nausea
- Constipation
Serious side effects can include:
- Thromboembolic events
- Severe allergic reactions
- Liver function abnormalities
Drug Interactions:
Pomalidomide may interact with other medications, including anticoagulants, immunosuppressants, and drugs that influence liver enzymes. Patients should inform their healthcare provider of all medications they are taking.
Storage:
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to report any signs of infection, unusual bruising or bleeding, or significant fatigue.
- Discuss the importance of using effective contraception throughout treatment and for a specified time afterward.
- Emphasize adherence to the prescribed dosing schedule and the necessity of regular monitoring.
Conclusion:
Pomalidomide offers a treatment option for multiple myeloma patients who have not responded to other therapies. Continuous communication with healthcare providers is vital for managing side effects and ensuring optimal therapeutic outcomes. Always consult with a healthcare professional for personalized medical advice.
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Cyclophosphamide Tablet (Cycloxan 50mg Tablet)
Product Price: Rs 100 / StripGet Best Price
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Product Details:
| Strength | 50 mg |
| Dose/Strength | 50 mg |
| Packaging Size | 10 Tablets in 1 Strip |
| Composition | Cyclophosphamide 50 mg |
| Brand | Cycloxan 50 mg Tablet |
| Manufacturer | Zydus Cadila |
| Treatment | Cancer Nephrotic syndrome |
Cyclophosphamide (Cycloxan 50mg Tablet) is a potent alkylating agent used to treat various cancers and autoimmune diseases. It works by interfering with DNA replication, preventing cancer cell growth and suppressing the immune system in conditions like lupus and rheumatoid arthritis. This medication requires careful monitoring to minimize side effects.
Indications for UseCyclophosphamide is indicated for:
- Cancer Treatment: Used for breast cancer, non-Hodgkin’s lymphoma, leukemias, ovarian cancer, and Wilm’s tumor.
- Autoimmune Diseases: Prescribed for severe cases of systemic lupus erythematosus (SLE), rheumatoid arthritis, and multiple sclerosis.
Cyclophosphamide is an alkylating agent that binds to DNA, preventing its replication and causing cancer cell death. It also suppresses the immune system by reducing the production of immune cells, which is beneficial in treating autoimmune diseases.
Dosage and Administration- Dosage: The dose of Cyclophosphamide 50mg tablets varies depending on the condition. For cancer, doses range from 50 mg to 200 mg daily. Lower doses are used for autoimmune diseases.
- Administration: Cyclophosphamide is taken orally once daily, usually with a full glass of water. Dosing should be adjusted based on the patient's response and blood test results.
Common Side Effects:
- Nausea and vomiting
- Fatigue and hair loss
- Loss of appetite and diarrhea
- Mouth sores and skin rashes
Serious Side Effects:
- Bone marrow suppression, leading to low blood counts and increased infection risk.
- Liver toxicity (elevated liver enzymes).
- Bladder irritation and hemorrhagic cystitis (blood in urine).
- Secondary cancers, such as leukemia, with long-term use.
Store Cyclophosphamide (Cycloxan 50mg tablets) at room temperature (15°C to 30°C or 59°F to 86°F), away from moisture and light. Keep in its original container, tightly closed, and out of reach of children.
Patient Counseling InformationPatients should be advised to:
- Hydrate well to prevent bladder irritation.
- Monitor for infections and report any unusual symptoms immediately.
- Complete the full treatment course, even if symptoms improve, to ensure full cancer remission or disease control.
Cyclophosphamide (Cycloxan 50mg Tablet) is a vital treatment for various cancers and autoimmune diseases. Proper dosing, regular blood tests, and careful monitoring are crucial to optimizing its benefits and minimizing risks.
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Imnovid Pomalidomide 4mg Capsule
Product Price: Rs 8,000 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 4 mg |
| Pack Type | 21 Capsules Per Bottle |
| Composition | Pomalidomide 4mg |
| Brand | Imnovid 4 mg |
| Manufactured By | Celgene Pharma |
| Treatment | Multiple Myeloma |
Imnovid Pomalidomide 4mg Capsule
Overview: Imnovid (Pomalidomide 4mg Capsule) is an oral immunomodulatory drug used to treat relapsed or refractory multiple myeloma (a type of blood cancer). Pomalidomide, the active ingredient, works by modulating the immune system, enhancing the body's ability to fight cancer cells, and inhibiting tumor growth. It is often used in combination with other medications such as dexamethasone to treat multiple myeloma patients who have previously undergone other treatments.
Indications: Imnovid 4mg Capsule is primarily indicated for:
- Relapsed or Refractory Multiple Myeloma: For patients who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor, and have shown disease progression.
- Treatment in Combination: Often prescribed with dexamethasone as part of a combination regimen.
Mechanism of Action: Pomalidomide, the active compound in Imnovid, belongs to a class of drugs known as immunomodulatory drugs (IMiDs). It works by:
- Modulating the immune system to activate natural killer (NK) cells, T-cells, and macrophages, which help fight cancer cells.
- Inhibiting the growth of tumor cells by interfering with the blood supply to the tumor (angiogenesis) and promoting apoptosis (programmed cell death).
Dosage and Administration:
- Recommended Dose: The typical starting dose is 4 mg once daily for 21 days followed by a 7-day rest period (28-day treatment cycle).
- Administration: Take the capsule orally with or without food. Swallow the capsule whole with a full glass of water. Do not open or crush the capsule.
Side Effects:
- Common Side Effects: Fatigue, nausea, constipation, fever, and rash.
- Serious Side Effects: Blood clots, low blood cell counts (neutropenia, thrombocytopenia), and teratogenicity (potential harm to a fetus, contraindicated in pregnancy).
Precautions:
- Pregnancy: Contraindicated during pregnancy due to the potential risk of birth defects.
- Blood Counts: Regular blood tests are necessary to monitor for low blood cell counts and ensure safety during treatment.
- Avoid Use with Certain Drugs: Can interact with other medications, including those affecting blood clotting.
Storage: Store Imnovid 4mg Capsule at room temperature (20°C to 25°C) in a dry place, away from light and moisture.
Conclusion: Imnovid Pomalidomide 4mg Capsule is an effective treatment for relapsed or refractory multiple myeloma, offering an option for patients who have not responded to other therapies. Regular monitoring and caution in pregnancy are critical to ensure safe and effective use.
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Tegonat 20mg Capsules
Product Price: Rs 4,000 / StripeGet Best Price
Product Brochure
Product Details:
| Packaging Size | 6*7 Capsules |
| Pack Size | 6*7 Capsules |
| Compostion | Gimeracil (5.8mg) + Oteracil (15.8mg) + Tegafur (20mg) |
| Brand | Tegonat 20mg |
| Menufacturer | Natco Pharma Ltd |
| Treatment | Gastric/Stomach Cancer |
Overview
Tegonat is a medication that contains paliperidone, an atypical antipsychotic used primarily for the treatment of schizophrenia and schizoaffective disorder.
- Schizophrenia: Effective in managing symptoms of schizophrenia in adults and adolescents.
- Schizoaffective Disorder: Used for the treatment of schizoaffective disorder in adults.
Paliperidone works by:
- Modulating Neurotransmitters: It primarily affects dopamine and serotonin receptors in the brain, helping to stabilize mood and behavior.
- Dosage: The typical starting dose for adults is usually 6 mg once daily. For some patients, the dose may be adjusted based on clinical response, with a maximum recommended dose of 12 mg per day. In certain cases, a 20 mg dose may be prescribed based on individual needs.
- Administration: Tegonat capsules can be taken with or without food. It's important to take them at the same time each day to maintain consistent levels in the bloodstream.
Common side effects may include:
- Drowsiness or sedation
- Weight gain
- Dizziness
- Akathisia (a feeling of inner restlessness)
- Increased heart rate
- Metabolic Changes: Monitor for potential weight gain, changes in blood glucose levels, and lipid levels, as paliperidone can contribute to metabolic syndrome.
- Extrapyramidal Symptoms (EPS): Patients should be monitored for movement disorders, including tremors or rigidity.
- Suicidal Thoughts: Regular assessment for any worsening of mood or emergence of suicidal thoughts is essential, especially during dose adjustments.
- Hypersensitivity: Known allergies to paliperidone or any components of the formulation.
- Severe Renal Impairment: Caution is advised in patients with significant kidney issues.
- Tegonat may interact with other medications, especially those affecting the central nervous system or causing QT prolongation. Always inform your healthcare provider about all medications and supplements being taken.
- Store Tegonat at room temperature, protected from moisture and light. Keep out of reach of children.
- Educate patients about the importance of adhering to the prescribed dosage and the potential side effects.
- Advise them to report any unusual symptoms, especially changes in mood or movement.
- Discuss lifestyle changes that may help manage side effects, such as diet and exercise.
Tegonat (20 mg Capsules) is an effective treatment option for managing schizophrenia and schizoaffective disorder. Proper administration, monitoring for side effects, and patient education are crucial for successful outcomes. Always consult a healthcare provider for personalized advice and guidance.
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Thalix Thalidomide 100 Mg Capsule
Product Price: Rs 800 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 100 mg |
| Packaging Type | Box |
| Prescription/Non prescription | Prescription |
| Shelf Life | 2 Years |
| Packing Size | 3x10 Capsule |
| Product Form | Capsule |
| Manufactured by | Fresenius kabi |
| Medicine form | Capsules |
| Medicine name | Thalidomide capsules usp |
| Medicine strength | 100 mg |
| Packaging size | 3x10 capsules |
| Warning | Not to be used by pregnant women |
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Abiron Abiraterone Acetate 250mg Tablet
Product Price: Rs 90,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Form | Tablet |
| Prescription/Non prescription | Prescription |
| Brand | Abiron |
| Composition | Abiraterone Acetate |
Abiron (Abiraterone Acetate) 250mg Tablet
Overview:
Abiron (Abiraterone Acetate) is an oral medication used in the treatment of metastatic castration-resistant prostate cancer (mCRPC). It works by inhibiting the production of androgens (male hormones), which fuel prostate cancer cell growth. By blocking the enzyme CYP17A1, Abiraterone reduces testosterone and other androgen levels, helping to slow cancer progression.
Indications:
Abiron is used for:
- Metastatic castration-resistant prostate cancer (mCRPC), particularly in patients who have undergone surgical or medical castration (low testosterone).
- Metastatic high-risk castration-sensitive prostate cancer (CSPC), in combination with prednisone, for patients who have not been treated with chemotherapy.
Mechanism of Action:
Abiraterone inhibits CYP17A1, an enzyme involved in androgen synthesis in the testes, adrenal glands, and prostate tumor tissue. By reducing androgen production, it slows the growth of prostate cancer cells that rely on androgens for survival.
Dosage and Administration:
- Recommended dose: 1000 mg (four 250 mg tablets) once daily.
- Administration: Take on an empty stomach (at least 1 hour before or 2 hours after meals). Do not take with food, as it may increase drug absorption and risk of side effects.
- Prednisone: Taken in combination with prednisone (5 mg twice daily) to help manage side effects, such as fluid retention and low potassium.
Side Effects:
Common side effects include:
- Fatigue
- Muscle/joint pain
- Hot flashes
- Diarrhea
- Elevated liver enzymes
Serious side effects include:
- Hypertension (high blood pressure)
- Hypokalemia (low potassium)
- Fluid retention: Swelling in feet, ankles, or legs
- Liver toxicity: Requires liver function monitoring
- Adrenal insufficiency: Weakness, dizziness, low blood pressure
Precautions:
- Pregnancy and breastfeeding: Contraindicated in pregnancy. Women who are pregnant or planning pregnancy should avoid handling the tablets.
- Liver function: Monitor liver enzymes regularly to prevent liver toxicity.
- Corticosteroid use: Should be used with prednisone to reduce side effects.
- Drug interactions: Abiron may interact with other medications affecting liver enzymes (e.g., CYP3A4 inhibitors).
Monitoring:
- Liver function: Regular liver enzyme tests.
- Blood pressure: Monitor for hypertension.
- Potassium levels: Check for hypokalemia.
Storage:
Store Abiron at room temperature (15°C to 30°C or 59°F to 86°F) in a cool, dry place, away from moisture. Keep out of reach of children.
Patient Counseling:
- Adherence: Take as prescribed. Do not stop without consulting your doctor.
- Side effects: Report severe swelling, difficulty breathing, or significant fatigue.
- Hydration: Stay hydrated to reduce muscle pain and fatigue.
Conclusion:
Abiron (Abiraterone Acetate) 250 mg tablets are a key treatment for metastatic castration-resistant prostate cancer (mCRPC). By lowering androgen levels, it helps slow cancer growth. Regular monitoring and adherence to the prescribed regimen are essential for effectiveness.
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Temodal Temozolomide 100mg Capsule
Product Price: Rs 8,900 / BoxGet Best Price
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Product Details:
| Strength | 100 mg |
| Prescription/Non prescription | Prescription |
| Product Form | Capsule |
| Brand | Temodal |
| Composition | Temozolomide |
| Pack Size | 5 Cap |
Temodal (Temozolomide) 100mg Capsule
Overview:
Temodal (Temozolomide) is an oral chemotherapy medication primarily used to treat glioblastoma multiforme (GBM), anaplastic astrocytoma, and other forms of brain tumors. Temozolomide is an alkylating agent that interferes with DNA replication in cancer cells, preventing them from dividing and proliferating. It is often used in combination with radiation therapy to increase its effectiveness in treating high-grade gliomas.
Indications:
Temodal 100mg Capsule is indicated for:
- Glioblastoma Multiforme (GBM): As part of adjuvant therapy following surgery and radiation therapy.
- Anaplastic Astrocytoma: For patients with this aggressive brain tumor type, following recurrence or progression after initial therapy.
Mechanism of Action:
Temozolomide is a prodrug, meaning it is metabolized in the body to its active form, monomethyl triazeno imidazole carboxamide (MTIC). MTIC methylates DNA, forming toxic DNA adducts that cause damage to the DNA structure, leading to cell cycle arrest and apoptosis (programmed cell death), especially in cancer cells. It is particularly effective in tumors with defective DNA repair mechanisms, such as glioblastoma.
Dosage and Administration:
- Recommended Dose: The typical dose for glioblastoma is 75 mg/m² once daily for 42 days, followed by a 28-day rest period. The dosage can be adjusted based on patient tolerance.
- Administration: Take Temodal 100mg capsules orally once a day, usually 1 hour before or 2 hours after food, to reduce the risk of gastrointestinal side effects. The capsule should be swallowed whole, without crushing or chewing.
- Missed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose. Do not double the dose.
Side Effects:
Common side effects include:
- Nausea, vomiting, fatigue, headache, and loss of appetite.
Serious side effects may include: - Bone marrow suppression: Leading to anemia, thrombocytopenia, and neutropenia (low blood counts).
- Infections: Higher risk of infections due to reduced white blood cells.
- Liver toxicity: Possible liver enzyme abnormalities requiring monitoring.
Precautions:
- Infections: Monitor for signs of infection, as Temodal can reduce white blood cell count.
- Pregnancy: Temozolomide is contraindicated during pregnancy, as it may harm the fetus.
- Liver Function: Periodic liver function tests are recommended during treatment.
Storage:
Store Temodal 100mg Capsules at room temperature (20°C to 25°C), away from light and moisture. Keep the capsules in their original container, tightly closed, and out of reach of children.
Conclusion:
Temodal (Temozolomide) 100mg Capsule is an essential treatment for glioblastoma multiforme and anaplastic astrocytoma. Careful monitoring of blood counts, liver function, and possible side effects is necessary to ensure safe and effective therapy.
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Anastrozole Tablets (Anatero 1mg Tablets)
Product Price: Rs 465 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 1 mg |
| Form | Tablet |
| Packaging Type | Stripe |
| Packaging Size | 1*10 Tablets |
| Brand | Anatero |
| Prescription/Non prescription | Prescription |
| Shelf Life | 2 Years |
| Medicine form | Tablet |
| Medicine name | Anastrozole tablets ip |
| Medicine strength | 1 mg |
| Packaging size | 1x10 tablets |
| Packaging type | Box |
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Thalix Thalidomide 50mg Capsule
Product Price: Rs 500 / BoxGet Best Price
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Product Details:
| Strength | 50 mg |
| Packaging Type | Box |
| Brand | Fresenius Kabi |
| Shelf Life | 24 Months |
| Product Form | Capsule |
| Pack Size | 3x10 Capsules |
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Axitinib Tablets (Axpero 5mg Tablets)
Product Price: Rs 1,500 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 5 mg |
| Form | Tablet |
| Prescription/Non prescription | Prescription |
| Item Name | Axpero |
| Pack Size | 2x14 Tab |
| Manufactured by | Intas |
| Medicine brand | Axpero 5 |
| Medicine form | Tablet |
| Medicine name | Axitinib tablets |
| Medicine strength | 5 mg |
| Packaging size | 2 x 14 tablets |
| Packaging type | Box |
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Anastrozole Tablets (Anarzole 1mg Tablets)
Product Price: Rs 250 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 1 mg |
| Packaging Size | 1*10 Tablets |
| Brand | Anarzole 1mg Tablet |
| Manufactured By | RPG Life Sciences Ltd |
| Composition | Anastrozole 1mg |
| Treatment | Breast cancer |
| Manufactured by | Beta drugs pvt.ltd. (unit of adley group) kharauni-lodhimaira road, vil. nandpur, tehsil baddi, distt solan, himachal pradesh |
| Marketed by | Rpg life sciences limited rpg house, 463, dr.a.b.road. worli, mumbai-400 030, india |
| Medicine brand | Anarzole |
| Medicine form | Tablet |
| Medicine name | Anastrozole tablets ip |
| Medicine strength | 1 mg |
| Packaging size | 1x 10 tablets |
| Packaging type | box |
| Salt composition | Anastrozole ip |
| Storage conditions | Store protected from light and moisture, at a temperature not exceeding 30ยฐ c. |
| Warning | Cytotoxic agent: to be sold by retail on the prescription of an oncologist, institution & specialists, hospitals, institution and cancer specialists only. |
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250mg Gliogen Temozolomide Capsules
Product Price: Rs 5,500 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Prescription/Non prescription | Prescription |
| Shelf Life | 2 Years |
| Usage/Application | Hospital |
| Item Name | Gliogen |
| Pack Size | 5 Cap |
| Composition | Temozolomide |
250 mg Gliogen (Temozolomide) Capsules
Overview:
Gliogen is the brand name for Temozolomide, an oral chemotherapy drug used primarily for glioblastoma multiforme (GBM) and anaplastic astrocytoma. It is an alkylating agent that interferes with cancer cell DNA, preventing the cells from dividing and growing.
Indication:
Gliogen 250 mg is used in the treatment of:
- Glioblastoma multiforme (GBM)
- Anaplastic astrocytoma
It is usually given after surgery and radiation or in combination with other treatments to help control tumor growth and prolong survival.
Mechanism of Action:
Temozolomide works by adding an alkyl group to the DNA of cancer cells, leading to DNA damage. This disrupts the ability of cancer cells to replicate, eventually causing cell death. It can cross the blood-brain barrier, making it effective for brain tumors.
Dosage and Administration:
- Starting dose: Typically 75 mg/m² per day for 42 consecutive days, taken orally before radiation.
- Maintenance dose: After radiation, the dose is increased to 150 mg/m² and 200 mg/m² in subsequent cycles.
- Administration: Take once daily, on an empty stomach, ideally 1 hour before or 2 hours after food.
- Cycle: Treatment is usually given for 6–12 cycles, with a 28-day rest period after the initial 42-day treatment.
Side Effects:
Common side effects include:
- Nausea and vomiting
- Fatigue
- Loss of appetite
- Headaches
- Hair loss (less frequent than other chemotherapy)
Serious side effects may include:
- Bone marrow suppression: Low white blood cells, platelets, or red blood cells, increasing the risk of infection and bleeding.
- Liver toxicity: Requires monitoring of liver enzymes.
- Pulmonary toxicity: Rare fluid buildup in the lungs.
- Infections: Increased risk due to low white blood cell count.
Monitoring:
Regular blood tests are needed to check for:
- White blood cells, platelets, and red blood cells.
- Liver function to detect any liver issues early.
Precautions:
- Pregnancy and breastfeeding: Temozolomide can harm a fetus and should not be used during pregnancy. It’s unknown if it passes into breast milk.
- Interactions: Inform your doctor about any other medications, as some may interact with temozolomide.
Storage:
- Store at room temperature (15°C to 30°C or 59°F to 86°F), in a cool, dry place.
- Keep tightly closed, out of reach of children.
Patient Counseling:
- Adherence: Take the medication as prescribed. Missing doses or stopping suddenly may reduce effectiveness.
- Side effects: Report any persistent symptoms such as fever, unusual bleeding, or difficulty breathing.
- Hydration: Drink plenty of fluids to reduce nausea and other side effects.
Conclusion:
Gliogen (Temozolomide) 250 mg is an important treatment for glioblastoma and other brain tumors, helping to slow tumor growth and improve survival. Regular monitoring and adherence to the prescribed regimen are essential to ensure treatment success and minimize side effects.
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Temoside Temozolomide 100mg Capsule
Product Price: Rs 3,500 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 100 mg |
| Brand | Cipla |
| Prescription/Non prescription | Prescription |
| Shelf Life | 2 Years |
| Usage/Application | Hospital |
| Composition | Temozolomide |
| Product Form | Capsule |
| Pack Size | 5 Cap |
Temoside (Temozolomide) 100mg Capsule
Overview:
Temoside (Temozolomide) is an oral chemotherapy agent used in the treatment of certain types of brain tumors, primarily glioblastoma multiforme (GBM) and anaplastic astrocytoma. It is an alkylating agent that works by damaging the DNA in cancer cells, preventing them from dividing and growing. Temozolomide is typically used as a part of combination therapy, often alongside radiation therapy, in the treatment of glioblastoma.
Indications:
Temoside 100mg Capsule is indicated for:
- Glioblastoma Multiforme (GBM): For patients who have undergone surgery and radiation therapy.
- Anaplastic Astrocytoma: For patients who have shown progression after initial treatment.
Mechanism of Action:
Temozolomide is an oral prodrug that is metabolized into its active form, MTIC (monomethyl triazeno imidazole carboxamide). MTIC methylates the DNA, resulting in the formation of highly toxic DNA adducts that prevent cell division. This leads to cell death, particularly in rapidly proliferating tumor cells. Temozolomide’s action is most effective against tumors with high DNA repair deficiencies.
Dosage and Administration:
- Recommended Dose: The typical dose for glioblastoma is 75 mg/m² daily for 42 days, followed by a 28-day rest period. The dose may be increased in subsequent cycles based on patient tolerance and response.
- Administration: Take Temoside 100mg capsules orally once a day, preferably on an empty stomach, 1 hour before or 2 hours after food. Swallow the capsule whole without crushing or chewing it.
- Missed Dose: If a dose is missed, take it as soon as possible unless it’s nearly time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Nausea, vomiting, fatigue, and loss of appetite.
Serious side effects may include: - Bone marrow suppression: Leading to low blood cell counts (anemia, thrombocytopenia, neutropenia).
- Infections: Increased risk due to lowered white blood cell counts.
- Liver toxicity: Elevated liver enzymes.
Precautions:
- Infection: Monitor for signs of infection, as Temozolomide may lower white blood cells.
- Pregnancy: Temozolomide is contraindicated during pregnancy due to potential harm to the fetus.
- Liver Function: Regular monitoring of liver function is recommended.
Storage:
Store Temoside 100mg Capsules at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Temoside 100mg Capsule is an effective chemotherapy drug for glioblastoma multiforme and anaplastic astrocytoma. Regular monitoring for side effects, especially related to blood counts and liver function, is essential to ensure safe and effective treatment.
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Temoside Temozolomide 250 Mg Capsule
Product Price: Rs 7,100 / BoxGet Best Price
Product Brochure
Product Details:
| Strength | 250 mg |
| Prescription/Non prescription | Prescription |
| Shelf Life | 2 Years |
| Usage/Application | Hospital |
| Product Form | Capsule |
| Pack Size | 5 Cap |
Temoside (Temozolomide) 250mg Capsule
Overview:
Temoside (Temozolomide) is an oral chemotherapy drug primarily used for the treatment of glioblastoma multiforme (GBM) and anaplastic astrocytoma, which are types of aggressive brain tumors. It is an alkylating agent that works by damaging the DNA of cancer cells, preventing them from dividing and proliferating. Temozolomide is often used in combination with radiation therapy for GBM, to enhance its effectiveness and improve patient outcomes.
Indications:
Temoside 250mg Capsule is indicated for:
- Glioblastoma Multiforme (GBM): For patients following surgery and radiation therapy as adjuvant treatment.
- Anaplastic Astrocytoma: In patients with this recurrent or progressive brain tumor, typically after initial treatments.
Mechanism of Action:
Temozolomide is a prodrug, which is converted in the body to its active form, monomethyl triazeno imidazole carboxamide (MTIC). MTIC methylates the DNA, causing toxic DNA damage and preventing its repair. This leads to cell cycle arrest and apoptosis (cell death), particularly in cancer cells. Glioblastomas, in particular, are susceptible to temozolomide because of their high rate of DNA repair deficiencies.
Dosage and Administration:
- Recommended Dose: The usual starting dose for glioblastoma is 75 mg/m² daily for 42 days, followed by a 28-day rest period. The dose may be adjusted depending on the patient’s condition and treatment response.
- Administration: Temozolomide 250mg capsules should be taken once daily, usually 1 hour before or 2 hours after meals to minimize gastrointestinal discomfort. Swallow the capsule whole, without crushing or chewing.
- Missed Dose: If a dose is missed, take it as soon as possible unless it is almost time for the next dose. Do not take two doses at once.
Side Effects:
Common side effects include:
- Nausea, vomiting, fatigue, loss of appetite, and headache.
Serious side effects may include: - Bone marrow suppression: This may lead to anemia, low platelet counts, and neutropenia (low white blood cells).
- Infections: Due to reduced white blood cell counts.
- Liver toxicity: Liver function tests should be monitored for signs of damage.
Precautions:
- Infections: Due to the risk of bone marrow suppression, patients should be monitored for signs of infection.
- Pregnancy: Temozolomide is contraindicated during pregnancy due to potential fetal harm.
- Liver Function: Periodic monitoring of liver enzymes is required during treatment.
Storage:
Store Temoside 250mg Capsules at room temperature (20°C to 25°C), away from light and moisture. Keep out of reach of children.
Conclusion:
Temoside 250mg Capsule is an important chemotherapy treatment for glioblastoma multiforme and anaplastic astrocytoma. It is effective in disrupting DNA replication in cancer cells. However, close monitoring of blood counts, liver function, and side effects is essential for patient safety.
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Piclib 125mg Capsule
Product Price: Rs 5,100 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 125 mg |
| Prescription/Non prescription | Non prescription |
| Packaging Size | 27 Capsules in 1 Bottle |
| Brand Name | Piclib |
| Manufacturer | Hetero Drugs Ltd |
| Composition | Palbociclib 125 mg |
| Directions for Use | Breast Cancer |
Description:
Palbociclib is an oral selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It works by disrupting cell cycle progression, particularly in cancer cells, thereby inhibiting tumor growth. Palbociclib is primarily used in the treatment of certain types of breast cancer.
Indications:
Palbociclib is indicated for:
- Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (HR+/HER2-) Breast Cancer: Used in combination with aromatase inhibitors or endocrine therapy for the treatment of postmenopausal women with advanced or metastatic disease.
Dosage and Administration:
- Dosage: The recommended dose of palbociclib is 125 mg taken orally once daily for 21 consecutive days, followed by 7 days off treatment (a 28-day cycle).
- Administration: Capsules should be taken at the same time each day, with or without food. It is important not to open or crush the capsules.
Common Side Effects:
- Neutropenia (low white blood cell count)
- Fatigue
- Nausea
- Diarrhea
- Anorexia
- Mouth sores
Precautions:
- Blood Counts Monitoring: Regular blood tests are required to monitor for neutropenia and other blood count abnormalities.
- Liver Function: Monitor liver function tests, as palbociclib can affect liver enzymes.
- Pregnancy and Breastfeeding: Palbociclib may cause fetal harm; it is contraindicated during pregnancy and breastfeeding. Women of childbearing age should use effective contraception during treatment.
Conclusion:
Palbociclib (PICLIB 125 mg) is an effective targeted therapy for hormone receptor-positive breast cancer. Patients should adhere to the prescribed dosage and administration guidelines and report any side effects or concerns to their healthcare provider. Regular monitoring and follow-up appointments are essential to ensure optimal treatment outcomes.
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Pomalid Pomalidomide 4 Mg Capsules
Product Price: Rs 5,000 / BottleGet Best Price
Product Brochure
Product Details:
| Strength | 4 mg |
| Packaging Size | 21 Capsules in 1 Bottle |
| Brand Name | Pomalid |
| Manufactured By | Natco Pharma Ltd |
| Treatment | To treat certain types of cancers (such as multiple myeloma, Kaposi sarcoma) |
Pomalidomide 4 mg Capsules (Pomalid 4 mg Capsules)
Indications:
Pomalidomide is indicated for the treatment of multiple myeloma in patients who have received at least two prior therapies, including lenalidomide and a proteasome inhibitor, and have demonstrated disease progression.
Mechanism of Action:
Pomalidomide is an immunomodulatory drug (IMiD) that exhibits anti-cancer activity by modulating the immune system and inhibiting the growth of myeloma cells. It enhances T-cell mediated immunity and has anti-angiogenic properties, disrupting the tumor microenvironment.
Dosage and Administration:
- Dosage: The recommended dose of Pomalidomide is 4 mg taken orally once daily.
- Administration: Capsules should be taken at the same time each day, with or without food. Swallow the capsules whole; do not open or chew.
Contraindications:
- Hypersensitivity to pomalidomide or any component of the formulation.
- Pregnancy: Pomalidomide is contraindicated in pregnant women due to potential fetal harm.
Warnings and Precautions:
- Blood Disorders: Monitor for neutropenia, thrombocytopenia, and anemia. Regular blood tests are recommended.
- Thromboembolic Events: Increased risk of deep vein thrombosis (DVT) and pulmonary embolism (PE). Consider thromboprophylaxis in at-risk patients.
- Pregnancy: Effective contraception is required for both men and women during treatment and for some time after discontinuation.
Side Effects:
Common side effects may include:
- Fatigue
- Neutropenia
- Anemia
- Nausea
- Diarrhea
Serious side effects can include:
- Thromboembolic events
- Severe allergic reactions
- Liver toxicity
Drug Interactions:
Pomalidomide may interact with other medications, including anticoagulants, immunosuppressants, and medications that affect liver enzymes. Always inform your healthcare provider of all medications you are taking.
Storage:
Store at room temperature, between 20°C to 25°C (68°F to 77°F). Protect from moisture and light. Keep out of reach of children.
Patient Counseling Information:
- Advise patients to report any signs of infection, unusual bruising or bleeding, or severe fatigue.
- Discuss the importance of using effective contraception during treatment and for a specified period afterward.
- Encourage adherence to the prescribed dosing schedule and regular follow-up appointments for monitoring.
Conclusion:
Pomalidomide is a valuable therapy for multiple myeloma, providing patients with a treatment option following previous therapies. Ongoing communication with healthcare providers is essential to manage potential side effects and ensure effective treatment. Always consult with a healthcare professional for personalized medical advice.
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Dasanat Dasatinib 20mg Tablets
Product Price: Rs 3,000 / BottleGet Best Price
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Product Details:
| Strength | 20 mg |
| Packaging Size | 60 Capsules |
| Compostion | Dasatinib |
| Brand | Dasanat 20 mg |
| Manufactured By | Natco Pharma Ltd |
| Uses | Blood cancer (Chronic myeloid leukaemia) |
Overview
Dasanat contains dasatinib, a targeted therapy used primarily in the treatment of certain types of cancer, particularly chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) with specific genetic mutations.
- Chronic Myeloid Leukemia (CML): Used in patients with Philadelphia chromosome-positive CML.
- Acute Lymphoblastic Leukemia (ALL): Indicated for Philadelphia chromosome-positive ALL in patients who are resistant or intolerant to prior therapy.
Dasatinib works by:
- Tyrosine Kinase Inhibition: It inhibits the activity of BCR-ABL, a fusion protein produced by the Philadelphia chromosome, which is responsible for the uncontrolled growth of cancer cells. By blocking this pathway, dasatinib helps to reduce the proliferation of cancer cells.
- Dosage: The typical starting dose is 100 mg once daily for CML or 140 mg once daily for ALL, but the exact dosage may be adjusted based on patient response and tolerance.
- Administration: Tablets should be taken orally, with or without food. It is essential to take the medication at the same time each day for consistent levels in the bloodstream.
Common side effects may include:
- Diarrhea
- Nausea
- Fatigue
- Headache
- Skin rash
- Fluid retention
- Blood Counts: Regular monitoring of blood counts is essential, as dasatinib can cause bone marrow suppression, leading to anemia, neutropenia, or thrombocytopenia.
- Cardiovascular Risk: Patients should be monitored for signs of heart problems, as dasatinib can cause cardiovascular issues, including arrhythmias.
- Liver Function: Monitor liver function tests, as dasatinib can cause liver toxicity.
- Hypersensitivity: Known allergies to dasatinib or any components of the formulation.
- Severe Liver Impairment: Use caution in patients with significant liver dysfunction.
Dasatinib may interact with:
- CYP3A4 Inhibitors and Inducers: Medications that affect liver enzymes can alter dasatinib levels. Patients should inform healthcare providers about all medications and supplements.
- Store Dasanat at room temperature, away from moisture and light. Keep out of reach of children.
- Educate patients about the importance of adherence to the prescribed regimen and the need for regular follow-up appointments to monitor blood counts and liver function.
- Advise them to report any unusual symptoms, particularly signs of bleeding, infection, or liver issues.
Dasanat (Dasatinib 20 mg Tablets) is a crucial treatment option for specific types of leukemia. Proper administration, monitoring for side effects, and patient education are vital for achieving the best treatment outcomes. Always consult a healthcare provider for personalized advice and guidance.
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